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Acoschimperoside P, 2’-acetate is isolated from the leaves of Vallaris glabra.
Acoschimperoside P, 2′-acetate is a natural glycoside with promising anticancer potential based on early-stage research that indicates possible induction of apoptosis, cell cycle arrest, and modulation of key signaling pathways (e.g., MAPK/ERK and PI3K/Akt). However, its pathways of action and overall clinical utility remain exploratory.
Strong cytotoxicity against human pancreatic and human prostate cancer.
Acoschimperoside is a naturally occurring glycoside that has gained interest due to its potential therapeutic properties, including anticancer effects. Glycosides are compounds in which a sugar molecule (glycone) is linked to a non-sugar moiety (aglycone). In the case of acoschimperoside, the specific sugar–aglycone combination contributes to its bioactivity.
• As a glycoside, acoschimperoside consists of a sugar moiety attached to a non-carbohydrate component. This structural motif is common among many plant-derived compounds that exhibit various pharmacological activities.
The sugar portion can influence the solubility, bioavailability, and even the targeting mechanism of the molecule within biological systems. The aglycone, on the other hand, frequently contributes to the molecule’s direct bioactivity, such as modulating signaling pathways involved in cell survival, apoptosis, or inflammation.
Similar glycosides have been studied for their effects on pathways like apoptosis (programmed cell death), cell cycle regulation, and inhibition of survival pathways (such as PI3K/AKT/mTOR and NF‑κB signaling).