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pid
Abbr
Name
Type
Features

Acetaminophen: The most common name in the United States.
Paracetamol: The name used in most of the world.
APAP: A common abbreviation used in biochemical and pharmacological studies.

Pathways:
-Cytochrome P450 Metabolism: NAPQI (N-acetyl-p-benzoquinone imine)
-Excess NAPQI depletes glutathione, a key antioxidant. The absence of sufficient glutathione leads to elevated oxidative stress.
-NF-κB Activation:
-Direct DNA Damage:

Excess results in increased oxidative stress, mitochondrial dysfunction, and ultimately hepatocellular damage (liver injury)




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