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pid
Abbr	5HT
Name	Serotonin, 5-hydroxytryptamine
Type
Features

Natural Product : 5HT, Serotonin, 5-hydroxytryptamine

5-HT (5-hydroxytryptamine), commonly known as serotonin, plays a significant role in Alzheimer’s disease (AD). Its dysfunction is associated with both the cognitive and neuropsychiatric symptoms of AD.
-Serotonin is a neurotransmitter involved in: Mood regulation, Sleep, Cognition, Appetite
-Decreased serotonin levels are seen in the brains of AD patients.
-Serotonin may reduce Aβ production via certain receptor pathways (e.g., 5-HT4 activation).

Natural Serotonin Enhancers
-5-HTP	                        Direct precursor to serotonin
-Curcumin	                MAO-A inhibitor (prevent serotonin breakdown)
-Resveratrol	                Inhibits MAO (prevent serotonin breakdown)
-Tryptophan	                Amino acid precursor to serotonin
-Saffron (crocin)	        Inhibits serotonin reuptake	↑ Synaptic 5-HT
-Green tea (L-theanine)
-Ginkgo biloba
-Omega-3 fatty acids	        Enhances serotonin release 
-Vitamin B6, B12, Folate	Cofactors in serotonin synthesis

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