Coenzyme Q10 (CoQ10), also known as ubiquinone, is a fat-soluble antioxidant and a critical component of the mitochondrial electron transport chain, essential for ATP production. Its potential role in Alzheimer’s disease (AD) and cancer has been increasingly studied, mainly due to its effects on oxidative stress, mitochondrial function, and cellular energy metabolism.
Two types: ubiquinone(standard) vs ubiquinol(more bioavailable)
-high content in beef heart
-Acts as an antioxidant, reducing ROS
-Some preclinical studies suggest CoQ10 may reduce Aβ-induced neurotoxicity
-CoQ10 is sometimes used with chemotherapy to reduce cardiotoxicity (especially with doxorubicin).
-Essential for ATP (energy) production.
-CoQ10 levels may drop by 25–40% in people taking statins.
-May support mitochondrial function in neurodegenerative diseases, including Alzheimer’s and Parkinson’s