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Natural Product : Sesame, Sesame seeds and Oil
Sesame (particularly sesame seeds and sesame oil) has been studied for its potential neuroprotective effects, including relevance to Alzheimer’s disease (AD)
-Sesame seeds are rich in sesamin, sesamol, and sesaminol, lignans with strong antioxidant properties.
-Sesamol has been shown to inhibit pro-inflammatory cytokines like TNF-α, IL-1β, and IL-6, and suppress NF-κB signaling
-may inhibit acetylcholinesterase (AChE)
-Sesamol may help inhibit Aβ aggregation
Mechanism Effect
↓ ROS (Oxidative stress) Protects neurons from oxidative damage
↓ NF-κB Reduces neuroinflammation
↓ AChE Increases acetylcholine levels
↓ Aβ aggregation Limits amyloid plaque formation
↑ BDNF Supports neurogenesis
Nutritional Richness
-Healthy fats: High in monounsaturated and polyunsaturated fats (especially omega-6)
-Protein: A good plant-based protein source
-Minerals: Rich in calcium, magnesium, iron, zinc, selenium, and copper
-Vitamins: Contains B vitamins (especially B1, B3, B6), vitamin E
-High in calories and fats—consume in moderation
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