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Cannabidiol (CBD) is a cannabinoid compound found in cannabis plants.
Cannabidiol (CBD) is a non-psychoactive phytocannabinoid derived from Cannabis sativa that has drawn interest for its potential anticancer properties.
Pathways:
-Mitochondrial dysfunction, with loss of membrane potential leading to the release of cytochrome c and activation of caspase cascades
-Receptor-Mediated Signaling (CB Receptors and Beyond)
-Can increase reactive oxygen species (ROS)
-Can induce ER stress, which activates the unfolded protein response.
-Suppress key survival and proliferation signaling cascades such as the PI3K/Akt/mTOR pathway.
-Impair angiogenesis