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Omega-3 fatty acid found in cold-water fish and some supplements.
– DHA is a major structural component of cell membranes in the brain, retina, and other tissues and plays a critical role in neural function and development.
Role in Cancer
Anti-Inflammatory Effects: – A reduction in chronic inflammation
Modulation of Cell Proliferation and Apoptosis
–Omega-3 fatty acids appear to influence cell cycle regulation and apoptosis (programmed cell death). By enhancing apoptosis and inhibiting proliferation, these agents may limit the growth of cancer cells.
Alteration of Membrane Composition and Signaling
–May affect processes such as angiogenesis (formation of new blood vessels), cell adhesion, and metastasis in cancer cells.
Impact on Oxidative Stress
–Although omega-3 fatty acids are prone to oxidation, their metabolites can have antioxidant properties. Balancing oxidation and antioxidant defenses is important in preventing oxidative stress—a known contributor to DNA damage and cancer development.
Anti-Angiogenic Effects
– Some studies have shown that EPA and DHA can inhibit angiogenesis.