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Prev  Next       Max= 4949

rid		ANTI-Cancer/IllnessPRO-Cancer/Illness

Prod	,2DG,2-DeoxyGlucose3BP,3-bromopyruvate5-ALA,5-Aminolevulinic acid5-FU,5-fluorouracil5-HTP,5-Hydroxytryptophanacet,acetaminophenacetaz,acetazolamideALC,Acetyl-l-carnitineAco,Acoschimperoside P, 2’-acetateAdag,AdagrasibTFdiG,Aflavin-3,3′-digallateATAGJ,Ai-Tong-An-Gao-JiAjoene,Ajoene (compound of Garlic)Akk,AkkermansiaAL,Allicin (mainly Garlic)almon,almonertinibAV,Aloe veraaLinA,alpha Linolenic acidALA,Alpha-Lipoic-AcidAlum,AluminumAMQ,AmodiaquineAnd,AndrographisACNs,AnthocyaninsantiOx,Anti-oxidantsAnzaroot,Anzaroot, Astragalus fasciculifolius BiossApi,Apigenin (mainly Parsley)AG,ArctigeninAroma,AromatherapyATO,Arsenic trioxideART/DHA,ArtemisininAP,Ascorbyl PalmitateAsh,Ashwagandha(Withaferin A)ASA,Aspirin -acetylsalicylic acidASTX,AstaxanthinAS,AstragalusATV,AtorvastatinAur,AuranofinBM,Bacopa monnieriBa,BaicaleinBA,Baicalinbemp,bempedoic acidBaP,benzo(a)pyreneBBM,BerbamineBBR,BerberinebetaCar,beta-carotene(VitA)B-Gluc,beta-glucansBetA,Betulinic acidBEV,Bevacizumab (brand Avastin)Bical,BicalutamideHCO3,BicarbonateBif,BifidobacteriumBCA,Biochanin ABP,Black phosphorusborn,borneolBor,BoronBTZ,BortezomibBos,Boswellia (frankincense)BML,BromelainBJ,Brucea javanicaBRU,brusatolBrut,BruteridinBF,BufalinBA,ButyrateCA,Caffeic acidCaff,CaffeineCalc,CalciumCRMs,Calorie Restriction MimeticsCPT,CamptothecinCBC,CannabichromeneCBD,CannabidiolCBDA,cannabidiolic acidcapec,capecitabineCAP,Capsaicincarbop,carboplatinCA,Carnosic acidCarno,CarnosineCAR,CarvacrolCats,Cat’s ClawCatechins,CatechinsCela,CelastrolCEL,CelecoxibCET,cetuximabCDT,chemodynamic therapyChemo,ChemotherapyChit,chitosanCGA,Chlorogenic acidCHL,ChlorophyllinCHOC,ChocolateChol,CholineCHr,ChrysinCin,CinnamonCisplatin,CisplatinCitrate,Citric AcidCoQ10,Coenzyme Q10Cu,Copper and Cu NanoParticlexCroc,CrocetinCuc,CucurbitacinCUR,CurcuminCUSP9,CUSP9CP,CyclopamineCBC/D,Cynanbungeigenin C (CBC) and D (CBD)Cyste,CysteamineDL,D-limoneneDand,Dandelion RootDAS,DasatinibDFE,Date Fruit ExtractDeg,DeguelinAnamu,dibenzyl trisulphide(DTS) from AnamuDCA,DichloroacetateDAP,Dichloroacetophenone(2,2-)Dicl,DiclofenacdietF,diet Fermented FoodsdietFMD,diet FMD Fasting Mimicking DietdietKeto,diet KetogenicdietMet,diet Methionine-Restricted DietdietP,diet Plant baseddietSTF,diet Short Term FastingdietMed,dietMediterraneanDHCA,Dihydrocaffeic AcidDSMO,Dimethyl SulfoxideDipy,DipyridamoleDSF,Disulfiramdocx,DocetaxelDHA,Docosahexaenoic AciddoxoR,doxorubicinEch,EchinaceaEGCG,EGCG (Epigallocatechin Gallate)EPA,eicosapentaenoic acidEP,Electrical PulsesEA,Ellagic acidRF,EMFEMD,EmodinMS-275,entinostatEPI,epirubicinerastin,erastinEst,EstrogenEDTA,ethylene diamine tetraacetic acidEDM,EvodiamineEx,ExerciseFenb,FenbendazoleFA,Ferulic acidFer,ferumoxytolFIS,FisetinFlav,flavonoidsFLS,Flickering Light StimulationFA,Folic AcidForm,FormononetinF,FucoidanGala,GalantamineGA,Gallic acidGallo,GalloflavinGamB,Gambogic AcidGABA,Gamma-aminobutyric acidGAR,GarcinolGB,gefitinib, erlotinibGEM,Gemcitabine (Gemzar)GEN,Genistein (soy isoflavone)Ger,GermacranolideGE,GermaniumGI,Ginger/6-Shogaol/GingerolGb,Ginkgo bilobaGins,GinsengGlaB,Glabrescione BGluc,GlucoseGlucDep,glucose deprivationGSH,GlutathioneGoldNP,Gold NanoParticlesGos,GossypolGe,Grapeseed extractGra,GraviolaHne,Helleborus niger extracts – Christmas RoseHibSad,Hibiscus sabdariffaHOO,High-Ozonide OilHNK,HonokiolHops,Hops (Humulus lupulus)HRT,Hormone replacement therapyHup,Huperzine A/Huperzia serrataH2,Hydrogen GasH2S,hydrogen sulfideHCQ,hydroxychloroquineHCAs,Hydroxycinnamic-acidHCA,HydroxyCitric AcidHTyr,HydroxytyrosolHT,HydroxyTyrosolHP,HyperosideHPT,HyperthermiaIMA,imatinibimmuno,immunotherapyI3C,Indole-3-carbinolInA,Inoscavin AIns,InositolIP,Inulin Prebioticiod,iodineIP6,IP6 (Inosital 1,2,3,4,5,6-hexakisphosphate)lpi,ipilimumabCPT-11,irinotecanFe,IronisoFl,isoflavonesitraC,itraconazoleIVM,IvermectinJG,JugloneKaempF,KaempferolL-A,L-AlinineL-Orn,L-ornithineLA,LactobacillusLF,LactoferrinLae,Laetrile B17 Amygdalinlamb,lambertianic acidLapC,LapacholLap,LapatinibLas,LasiodinLEC,LecithinLE,Licoricelign,lignansLip,Lipoic acidLDN,low dose naltrexoneLut,LuteinLT,LuteolinLyco,LycopeneMg,MagnesiumMFrot,Magnetic Field RotatingMF,Magnetic FieldsMNPs,magnetic nanoparticlesMAG,MagnololMatr,MatrineMCT,MCToilmeben,mebendazoleMEL,MelatoninMel,MelitidinMET,MetforminMTX,methotrexateMeJa,Methyl JasmonateM-Blu,Methylene blueMGO,MethylglyoxalMeSA,methylseleninic acidMSM,MethylsulfonylmethanemetroC,metronomic chemoMT,MistletoeMCP,Modified Citrus PectinMoringa,Moringa oleiferaMushCha,Mushroom ChagamushLions,Mushroom Lion’s ManeMushMait,Mushroom MaitakeMushPL,Mushroom Phellinus. linteusMushReishi,Mushroom ReishiMushShi,Mushroom Shiitake, AHCCmushTT,mushroom Turkey TailMyr,MyricetinMyrrh,MyrrhNAC,N-Acetyl-CysteineNarG,NaringinNRF,nelfinavir/ViraceptNCL,Niclosamide (Niclocide)NAD,nicotinamide adenine dinucleotideNimb,NimbolideNIV,nivolumabNos,NoscapineOctr,octreotideOleic Acid,Oleic AcidOLEC,OleocanthalOLE,OleuropeinOlive Oil,Olive OilOLST,OrlistatOA,Oroxylin AOA,Oroxylin-AOsi,OsimertinibOXA,OxaliplatinOAA,oxaloacetateOxy,Oxygen, HyperbaricPA,Pachymic acidPacT,PaclitaxelPap,papainPart,ParthenolidePawPaw,Paw PawPem,pembrolizumabP,PeppermintPer,PerillapH-AT,pH-Alkalization TherapyPEITC,Phenethyl isothiocyanatePB,PhenylbutyratePS,PhosphatidylserinePDT,Photodynamic TherapyPFB,Physalin F & BPI,PiperinePL,PiperlonguminePIT,PitavastatinPlum,PlumbaginPEG,polyethylene glycolK+,PotassiumPreB,PrebioticPACs,ProanthocyanidinsProBio,probioticsPBG,Propolis -bee gluePG,Propyl gallatePTS,PterostilbenePurp,PurpuronePhen,PXD, phenoxodiolQC,QuercetinRF,Radio FrequencyRad,Radiotherapy/RadiationRalox,raloxifenRAPA,RapamycinRSL3,Ras-selective lethal 3RSQ,ResiquimodRES,ResveratrolRiv,RivastigmineRosA,Rosmarinic acidRT,RutinSAMe,S-adenosyl-L-methionineSB,Saccharomyces boulardiiSY,Safflower yellowSS,Saikosaponin B1 and DSal,salinomycinSM,Salvia miltiorrhizaSage,Salvia officinalisSANG,SanguinarineSco,ScoulerineSelenate,SelenateSel,SeleniteSe,SeleniumSeMet,selenomethioninesericin,sericin5HT,Serotonin, 5-hydroxytryptamineSesame,Sesame seeds and OilShank,ShankhpushpiSK,ShikoninFulvicA,Shilajit/Fulvic AcidGSL,Siegesbeckia glabrescensSilicon,Silicic AcidSNP,Silver-NanoParticlesSIL,Silymarin (Milk Thistle) silibininSIM,SimvastatinSDT,SonoDynamic Therapy UltraSoundSRF,Sorafenib (brand name Nexavar)Sper,SpermidineSqu,Squalenestatins,statinsSulfas,SulfasalazineSFN,Sulforaphane (mainly Broccoli)SNT,sunitinibSuD,Sutherlandioside DTam,tamoxifenTaur,TaurineTMZ,temozolomideTF,TheaflavinTb,TheobromineTV,Thymol-Thymus vulgarisTQ,ThymoquinoneTC,Tinospora CordifoliaTiO2,Titanium DioxideTomatine,TomatineTACE,Transarterial ChemoembolizationTras,TrastuzumabTSA,Trichostatin ATrip,triptolideTu,TulsiTTT,Tumor Treating FieldsUkrain,Ukrainurea,ureaUro,UrolithinUA,Ursolic acidVem,verapamilVitA,RetA,Vitamin A, Retinoic AcidVitB1/Thiamine,Vitamin B1/ThiamineVitB12,Vitamin B12VitB2,Vitamin B2,RiboflavinVitB3,Vitamin B3,NiacinVitB5,Vitamin B5,Pantothenic AcidVitB6,Vitamin B6,pyridoxineVitC,Vitamin C (Ascorbic Acid)VitD3,Vitamin D3VitE,Vitamin EVitK2,Vitamin K2VitK3,VitK3,menadioneSAHA,VorinostatWBV,Whole Body VibrationWog,WogoninWor,Woreninewortm,wortmanninXyl,XylitolZeax,ZeaxanthinZeo,ZeoliteZER,ZerumboneZ,ZincZO,Zinc Oxideβ�Ele,β�ElemeneGLA,γ-linolenic acid (Borage Oil)γ-Toc,γ-Tocotrienol	Syn1	,2DG,2-DeoxyGlucose3BP,3-bromopyruvate5-ALA,5-Aminolevulinic acid5-FU,5-fluorouracil5-HTP,5-Hydroxytryptophanacet,acetaminophenacetaz,acetazolamideALC,Acetyl-l-carnitineAco,Acoschimperoside P, 2’-acetateAdag,AdagrasibTFdiG,Aflavin-3,3′-digallateATAGJ,Ai-Tong-An-Gao-JiAjoene,Ajoene (compound of Garlic)Akk,AkkermansiaAL,Allicin (mainly Garlic)almon,almonertinibAV,Aloe veraaLinA,alpha Linolenic acidALA,Alpha-Lipoic-AcidAlum,AluminumAMQ,AmodiaquineAnd,AndrographisACNs,AnthocyaninsantiOx,Anti-oxidantsAnzaroot,Anzaroot, Astragalus fasciculifolius BiossApi,Apigenin (mainly Parsley)AG,ArctigeninAroma,AromatherapyATO,Arsenic trioxideART/DHA,ArtemisininAP,Ascorbyl PalmitateAsh,Ashwagandha(Withaferin A)ASA,Aspirin -acetylsalicylic acidASTX,AstaxanthinAS,AstragalusATV,AtorvastatinAur,AuranofinBM,Bacopa monnieriBa,BaicaleinBA,Baicalinbemp,bempedoic acidBaP,benzo(a)pyreneBBM,BerbamineBBR,BerberinebetaCar,beta-carotene(VitA)B-Gluc,beta-glucansBetA,Betulinic acidBEV,Bevacizumab (brand Avastin)Bical,BicalutamideHCO3,BicarbonateBif,BifidobacteriumBCA,Biochanin ABP,Black phosphorusborn,borneolBor,BoronBTZ,BortezomibBos,Boswellia (frankincense)BML,BromelainBJ,Brucea javanicaBRU,brusatolBrut,BruteridinBF,BufalinBA,ButyrateCA,Caffeic acidCaff,CaffeineCalc,CalciumCRMs,Calorie Restriction MimeticsCPT,CamptothecinCBC,CannabichromeneCBD,CannabidiolCBDA,cannabidiolic acidcapec,capecitabineCAP,Capsaicincarbop,carboplatinCA,Carnosic acidCarno,CarnosineCAR,CarvacrolCats,Cat’s ClawCatechins,CatechinsCela,CelastrolCEL,CelecoxibCET,cetuximabCDT,chemodynamic therapyChemo,ChemotherapyChit,chitosanCGA,Chlorogenic acidCHL,ChlorophyllinCHOC,ChocolateChol,CholineCHr,ChrysinCin,CinnamonCisplatin,CisplatinCitrate,Citric AcidCoQ10,Coenzyme Q10Cu,Copper and Cu NanoParticlexCroc,CrocetinCuc,CucurbitacinCUR,CurcuminCUSP9,CUSP9CP,CyclopamineCBC/D,Cynanbungeigenin C (CBC) and D (CBD)Cyste,CysteamineDL,D-limoneneDand,Dandelion RootDAS,DasatinibDFE,Date Fruit ExtractDeg,DeguelinAnamu,dibenzyl trisulphide(DTS) from AnamuDCA,DichloroacetateDAP,Dichloroacetophenone(2,2-)Dicl,DiclofenacdietF,diet Fermented FoodsdietFMD,diet FMD Fasting Mimicking DietdietKeto,diet KetogenicdietMet,diet Methionine-Restricted DietdietP,diet Plant baseddietSTF,diet Short Term FastingdietMed,dietMediterraneanDHCA,Dihydrocaffeic AcidDSMO,Dimethyl SulfoxideDipy,DipyridamoleDSF,Disulfiramdocx,DocetaxelDHA,Docosahexaenoic AciddoxoR,doxorubicinEch,EchinaceaEGCG,EGCG (Epigallocatechin Gallate)EPA,eicosapentaenoic acidEP,Electrical PulsesEA,Ellagic acidRF,EMFEMD,EmodinMS-275,entinostatEPI,epirubicinerastin,erastinEst,EstrogenEDTA,ethylene diamine tetraacetic acidEDM,EvodiamineEx,ExerciseFenb,FenbendazoleFA,Ferulic acidFer,ferumoxytolFIS,FisetinFlav,flavonoidsFLS,Flickering Light StimulationFA,Folic AcidForm,FormononetinF,FucoidanGala,GalantamineGA,Gallic acidGallo,GalloflavinGamB,Gambogic AcidGABA,Gamma-aminobutyric acidGAR,GarcinolGB,gefitinib, erlotinibGEM,Gemcitabine (Gemzar)GEN,Genistein (soy isoflavone)Ger,GermacranolideGE,GermaniumGI,Ginger/6-Shogaol/GingerolGb,Ginkgo bilobaGins,GinsengGlaB,Glabrescione BGluc,GlucoseGlucDep,glucose deprivationGSH,GlutathioneGoldNP,Gold NanoParticlesGos,GossypolGe,Grapeseed extractGra,GraviolaHne,Helleborus niger extracts – Christmas RoseHibSad,Hibiscus sabdariffaHOO,High-Ozonide OilHNK,HonokiolHops,Hops (Humulus lupulus)HRT,Hormone replacement therapyHup,Huperzine A/Huperzia serrataH2,Hydrogen GasH2S,hydrogen sulfideHCQ,hydroxychloroquineHCAs,Hydroxycinnamic-acidHCA,HydroxyCitric AcidHTyr,HydroxytyrosolHT,HydroxyTyrosolHP,HyperosideHPT,HyperthermiaIMA,imatinibimmuno,immunotherapyI3C,Indole-3-carbinolInA,Inoscavin AIns,InositolIP,Inulin Prebioticiod,iodineIP6,IP6 (Inosital 1,2,3,4,5,6-hexakisphosphate)lpi,ipilimumabCPT-11,irinotecanFe,IronisoFl,isoflavonesitraC,itraconazoleIVM,IvermectinJG,JugloneKaempF,KaempferolL-A,L-AlinineL-Orn,L-ornithineLA,LactobacillusLF,LactoferrinLae,Laetrile B17 Amygdalinlamb,lambertianic acidLapC,LapacholLap,LapatinibLas,LasiodinLEC,LecithinLE,Licoricelign,lignansLip,Lipoic acidLDN,low dose naltrexoneLut,LuteinLT,LuteolinLyco,LycopeneMg,MagnesiumMFrot,Magnetic Field RotatingMF,Magnetic FieldsMNPs,magnetic nanoparticlesMAG,MagnololMatr,MatrineMCT,MCToilmeben,mebendazoleMEL,MelatoninMel,MelitidinMET,MetforminMTX,methotrexateMeJa,Methyl JasmonateM-Blu,Methylene blueMGO,MethylglyoxalMeSA,methylseleninic acidMSM,MethylsulfonylmethanemetroC,metronomic chemoMT,MistletoeMCP,Modified Citrus PectinMoringa,Moringa oleiferaMushCha,Mushroom ChagamushLions,Mushroom Lion’s ManeMushMait,Mushroom MaitakeMushPL,Mushroom Phellinus. linteusMushReishi,Mushroom ReishiMushShi,Mushroom Shiitake, AHCCmushTT,mushroom Turkey TailMyr,MyricetinMyrrh,MyrrhNAC,N-Acetyl-CysteineNarG,NaringinNRF,nelfinavir/ViraceptNCL,Niclosamide (Niclocide)NAD,nicotinamide adenine dinucleotideNimb,NimbolideNIV,nivolumabNos,NoscapineOctr,octreotideOleic Acid,Oleic AcidOLEC,OleocanthalOLE,OleuropeinOlive Oil,Olive OilOLST,OrlistatOA,Oroxylin AOA,Oroxylin-AOsi,OsimertinibOXA,OxaliplatinOAA,oxaloacetateOxy,Oxygen, HyperbaricPA,Pachymic acidPacT,PaclitaxelPap,papainPart,ParthenolidePawPaw,Paw PawPem,pembrolizumabP,PeppermintPer,PerillapH-AT,pH-Alkalization TherapyPEITC,Phenethyl isothiocyanatePB,PhenylbutyratePS,PhosphatidylserinePDT,Photodynamic TherapyPFB,Physalin F & BPI,PiperinePL,PiperlonguminePIT,PitavastatinPlum,PlumbaginPEG,polyethylene glycolK+,PotassiumPreB,PrebioticPACs,ProanthocyanidinsProBio,probioticsPBG,Propolis -bee gluePG,Propyl gallatePTS,PterostilbenePurp,PurpuronePhen,PXD, phenoxodiolQC,QuercetinRF,Radio FrequencyRad,Radiotherapy/RadiationRalox,raloxifenRAPA,RapamycinRSL3,Ras-selective lethal 3RSQ,ResiquimodRES,ResveratrolRiv,RivastigmineRosA,Rosmarinic acidRT,RutinSAMe,S-adenosyl-L-methionineSB,Saccharomyces boulardiiSY,Safflower yellowSS,Saikosaponin B1 and DSal,salinomycinSM,Salvia miltiorrhizaSage,Salvia officinalisSANG,SanguinarineSco,ScoulerineSelenate,SelenateSel,SeleniteSe,SeleniumSeMet,selenomethioninesericin,sericin5HT,Serotonin, 5-hydroxytryptamineSesame,Sesame seeds and OilShank,ShankhpushpiSK,ShikoninFulvicA,Shilajit/Fulvic AcidGSL,Siegesbeckia glabrescensSilicon,Silicic AcidSNP,Silver-NanoParticlesSIL,Silymarin (Milk Thistle) silibininSIM,SimvastatinSDT,SonoDynamic Therapy UltraSoundSRF,Sorafenib (brand name Nexavar)Sper,SpermidineSqu,Squalenestatins,statinsSulfas,SulfasalazineSFN,Sulforaphane (mainly Broccoli)SNT,sunitinibSuD,Sutherlandioside DTam,tamoxifenTaur,TaurineTMZ,temozolomideTF,TheaflavinTb,TheobromineTV,Thymol-Thymus vulgarisTQ,ThymoquinoneTC,Tinospora CordifoliaTiO2,Titanium DioxideTomatine,TomatineTACE,Transarterial ChemoembolizationTras,TrastuzumabTSA,Trichostatin ATrip,triptolideTu,TulsiTTT,Tumor Treating FieldsUkrain,Ukrainurea,ureaUro,UrolithinUA,Ursolic acidVem,verapamilVitA,RetA,Vitamin A, Retinoic AcidVitB1/Thiamine,Vitamin B1/ThiamineVitB12,Vitamin B12VitB2,Vitamin B2,RiboflavinVitB3,Vitamin B3,NiacinVitB5,Vitamin B5,Pantothenic AcidVitB6,Vitamin B6,pyridoxineVitC,Vitamin C (Ascorbic Acid)VitD3,Vitamin D3VitE,Vitamin EVitK2,Vitamin K2VitK3,VitK3,menadioneSAHA,VorinostatWBV,Whole Body VibrationWog,WogoninWor,Woreninewortm,wortmanninXyl,XylitolZeax,ZeaxanthinZeo,ZeoliteZER,ZerumboneZ,ZincZO,Zinc Oxideβ�Ele,β�ElemeneGLA,γ-linolenic acid (Borage Oil)γ-Toc,γ-Tocotrienol
Syn2	,2DG,2-DeoxyGlucose3BP,3-bromopyruvate5-ALA,5-Aminolevulinic acid5-FU,5-fluorouracil5-HTP,5-Hydroxytryptophanacet,acetaminophenacetaz,acetazolamideALC,Acetyl-l-carnitineAco,Acoschimperoside P, 2’-acetateAdag,AdagrasibTFdiG,Aflavin-3,3′-digallateATAGJ,Ai-Tong-An-Gao-JiAjoene,Ajoene (compound of Garlic)Akk,AkkermansiaAL,Allicin (mainly Garlic)almon,almonertinibAV,Aloe veraaLinA,alpha Linolenic acidALA,Alpha-Lipoic-AcidAlum,AluminumAMQ,AmodiaquineAnd,AndrographisACNs,AnthocyaninsantiOx,Anti-oxidantsAnzaroot,Anzaroot, Astragalus fasciculifolius BiossApi,Apigenin (mainly Parsley)AG,ArctigeninAroma,AromatherapyATO,Arsenic trioxideART/DHA,ArtemisininAP,Ascorbyl PalmitateAsh,Ashwagandha(Withaferin A)ASA,Aspirin -acetylsalicylic acidASTX,AstaxanthinAS,AstragalusATV,AtorvastatinAur,AuranofinBM,Bacopa monnieriBa,BaicaleinBA,Baicalinbemp,bempedoic acidBaP,benzo(a)pyreneBBM,BerbamineBBR,BerberinebetaCar,beta-carotene(VitA)B-Gluc,beta-glucansBetA,Betulinic acidBEV,Bevacizumab (brand Avastin)Bical,BicalutamideHCO3,BicarbonateBif,BifidobacteriumBCA,Biochanin ABP,Black phosphorusborn,borneolBor,BoronBTZ,BortezomibBos,Boswellia (frankincense)BML,BromelainBJ,Brucea javanicaBRU,brusatolBrut,BruteridinBF,BufalinBA,ButyrateCA,Caffeic acidCaff,CaffeineCalc,CalciumCRMs,Calorie Restriction MimeticsCPT,CamptothecinCBC,CannabichromeneCBD,CannabidiolCBDA,cannabidiolic acidcapec,capecitabineCAP,Capsaicincarbop,carboplatinCA,Carnosic acidCarno,CarnosineCAR,CarvacrolCats,Cat’s ClawCatechins,CatechinsCela,CelastrolCEL,CelecoxibCET,cetuximabCDT,chemodynamic therapyChemo,ChemotherapyChit,chitosanCGA,Chlorogenic acidCHL,ChlorophyllinCHOC,ChocolateChol,CholineCHr,ChrysinCin,CinnamonCisplatin,CisplatinCitrate,Citric AcidCoQ10,Coenzyme Q10Cu,Copper and Cu NanoParticlexCroc,CrocetinCuc,CucurbitacinCUR,CurcuminCUSP9,CUSP9CP,CyclopamineCBC/D,Cynanbungeigenin C (CBC) and D (CBD)Cyste,CysteamineDL,D-limoneneDand,Dandelion RootDAS,DasatinibDFE,Date Fruit ExtractDeg,DeguelinAnamu,dibenzyl trisulphide(DTS) from AnamuDCA,DichloroacetateDAP,Dichloroacetophenone(2,2-)Dicl,DiclofenacdietF,diet Fermented FoodsdietFMD,diet FMD Fasting Mimicking DietdietKeto,diet KetogenicdietMet,diet Methionine-Restricted DietdietP,diet Plant baseddietSTF,diet Short Term FastingdietMed,dietMediterraneanDHCA,Dihydrocaffeic AcidDSMO,Dimethyl SulfoxideDipy,DipyridamoleDSF,Disulfiramdocx,DocetaxelDHA,Docosahexaenoic AciddoxoR,doxorubicinEch,EchinaceaEGCG,EGCG (Epigallocatechin Gallate)EPA,eicosapentaenoic acidEP,Electrical PulsesEA,Ellagic acidRF,EMFEMD,EmodinMS-275,entinostatEPI,epirubicinerastin,erastinEst,EstrogenEDTA,ethylene diamine tetraacetic acidEDM,EvodiamineEx,ExerciseFenb,FenbendazoleFA,Ferulic acidFer,ferumoxytolFIS,FisetinFlav,flavonoidsFLS,Flickering Light StimulationFA,Folic AcidForm,FormononetinF,FucoidanGala,GalantamineGA,Gallic acidGallo,GalloflavinGamB,Gambogic AcidGABA,Gamma-aminobutyric acidGAR,GarcinolGB,gefitinib, erlotinibGEM,Gemcitabine (Gemzar)GEN,Genistein (soy isoflavone)Ger,GermacranolideGE,GermaniumGI,Ginger/6-Shogaol/GingerolGb,Ginkgo bilobaGins,GinsengGlaB,Glabrescione BGluc,GlucoseGlucDep,glucose deprivationGSH,GlutathioneGoldNP,Gold NanoParticlesGos,GossypolGe,Grapeseed extractGra,GraviolaHne,Helleborus niger extracts – Christmas RoseHibSad,Hibiscus sabdariffaHOO,High-Ozonide OilHNK,HonokiolHops,Hops (Humulus lupulus)HRT,Hormone replacement therapyHup,Huperzine A/Huperzia serrataH2,Hydrogen GasH2S,hydrogen sulfideHCQ,hydroxychloroquineHCAs,Hydroxycinnamic-acidHCA,HydroxyCitric AcidHTyr,HydroxytyrosolHT,HydroxyTyrosolHP,HyperosideHPT,HyperthermiaIMA,imatinibimmuno,immunotherapyI3C,Indole-3-carbinolInA,Inoscavin AIns,InositolIP,Inulin Prebioticiod,iodineIP6,IP6 (Inosital 1,2,3,4,5,6-hexakisphosphate)lpi,ipilimumabCPT-11,irinotecanFe,IronisoFl,isoflavonesitraC,itraconazoleIVM,IvermectinJG,JugloneKaempF,KaempferolL-A,L-AlinineL-Orn,L-ornithineLA,LactobacillusLF,LactoferrinLae,Laetrile B17 Amygdalinlamb,lambertianic acidLapC,LapacholLap,LapatinibLas,LasiodinLEC,LecithinLE,Licoricelign,lignansLip,Lipoic acidLDN,low dose naltrexoneLut,LuteinLT,LuteolinLyco,LycopeneMg,MagnesiumMFrot,Magnetic Field RotatingMF,Magnetic FieldsMNPs,magnetic nanoparticlesMAG,MagnololMatr,MatrineMCT,MCToilmeben,mebendazoleMEL,MelatoninMel,MelitidinMET,MetforminMTX,methotrexateMeJa,Methyl JasmonateM-Blu,Methylene blueMGO,MethylglyoxalMeSA,methylseleninic acidMSM,MethylsulfonylmethanemetroC,metronomic chemoMT,MistletoeMCP,Modified Citrus PectinMoringa,Moringa oleiferaMushCha,Mushroom ChagamushLions,Mushroom Lion’s ManeMushMait,Mushroom MaitakeMushPL,Mushroom Phellinus. linteusMushReishi,Mushroom ReishiMushShi,Mushroom Shiitake, AHCCmushTT,mushroom Turkey TailMyr,MyricetinMyrrh,MyrrhNAC,N-Acetyl-CysteineNarG,NaringinNRF,nelfinavir/ViraceptNCL,Niclosamide (Niclocide)NAD,nicotinamide adenine dinucleotideNimb,NimbolideNIV,nivolumabNos,NoscapineOctr,octreotideOleic Acid,Oleic AcidOLEC,OleocanthalOLE,OleuropeinOlive Oil,Olive OilOLST,OrlistatOA,Oroxylin AOA,Oroxylin-AOsi,OsimertinibOXA,OxaliplatinOAA,oxaloacetateOxy,Oxygen, HyperbaricPA,Pachymic acidPacT,PaclitaxelPap,papainPart,ParthenolidePawPaw,Paw PawPem,pembrolizumabP,PeppermintPer,PerillapH-AT,pH-Alkalization TherapyPEITC,Phenethyl isothiocyanatePB,PhenylbutyratePS,PhosphatidylserinePDT,Photodynamic TherapyPFB,Physalin F & BPI,PiperinePL,PiperlonguminePIT,PitavastatinPlum,PlumbaginPEG,polyethylene glycolK+,PotassiumPreB,PrebioticPACs,ProanthocyanidinsProBio,probioticsPBG,Propolis -bee gluePG,Propyl gallatePTS,PterostilbenePurp,PurpuronePhen,PXD, phenoxodiolQC,QuercetinRF,Radio FrequencyRad,Radiotherapy/RadiationRalox,raloxifenRAPA,RapamycinRSL3,Ras-selective lethal 3RSQ,ResiquimodRES,ResveratrolRiv,RivastigmineRosA,Rosmarinic acidRT,RutinSAMe,S-adenosyl-L-methionineSB,Saccharomyces boulardiiSY,Safflower yellowSS,Saikosaponin B1 and DSal,salinomycinSM,Salvia miltiorrhizaSage,Salvia officinalisSANG,SanguinarineSco,ScoulerineSelenate,SelenateSel,SeleniteSe,SeleniumSeMet,selenomethioninesericin,sericin5HT,Serotonin, 5-hydroxytryptamineSesame,Sesame seeds and OilShank,ShankhpushpiSK,ShikoninFulvicA,Shilajit/Fulvic AcidGSL,Siegesbeckia glabrescensSilicon,Silicic AcidSNP,Silver-NanoParticlesSIL,Silymarin (Milk Thistle) silibininSIM,SimvastatinSDT,SonoDynamic Therapy UltraSoundSRF,Sorafenib (brand name Nexavar)Sper,SpermidineSqu,Squalenestatins,statinsSulfas,SulfasalazineSFN,Sulforaphane (mainly Broccoli)SNT,sunitinibSuD,Sutherlandioside DTam,tamoxifenTaur,TaurineTMZ,temozolomideTF,TheaflavinTb,TheobromineTV,Thymol-Thymus vulgarisTQ,ThymoquinoneTC,Tinospora CordifoliaTiO2,Titanium DioxideTomatine,TomatineTACE,Transarterial ChemoembolizationTras,TrastuzumabTSA,Trichostatin ATrip,triptolideTu,TulsiTTT,Tumor Treating FieldsUkrain,Ukrainurea,ureaUro,UrolithinUA,Ursolic acidVem,verapamilVitA,RetA,Vitamin A, Retinoic AcidVitB1/Thiamine,Vitamin B1/ThiamineVitB12,Vitamin B12VitB2,Vitamin B2,RiboflavinVitB3,Vitamin B3,NiacinVitB5,Vitamin B5,Pantothenic AcidVitB6,Vitamin B6,pyridoxineVitC,Vitamin C (Ascorbic Acid)VitD3,Vitamin D3VitE,Vitamin EVitK2,Vitamin K2VitK3,VitK3,menadioneSAHA,VorinostatWBV,Whole Body VibrationWog,WogoninWor,Woreninewortm,wortmanninXyl,XylitolZeax,ZeaxanthinZeo,ZeoliteZER,ZerumboneZ,ZincZO,Zinc Oxideβ�Ele,β�ElemeneGLA,γ-linolenic acid (Borage Oil)γ-Toc,γ-Tocotrienol	Syn3	,2DG,2-DeoxyGlucose3BP,3-bromopyruvate5-ALA,5-Aminolevulinic acid5-FU,5-fluorouracil5-HTP,5-Hydroxytryptophanacet,acetaminophenacetaz,acetazolamideALC,Acetyl-l-carnitineAco,Acoschimperoside P, 2’-acetateAdag,AdagrasibTFdiG,Aflavin-3,3′-digallateATAGJ,Ai-Tong-An-Gao-JiAjoene,Ajoene (compound of Garlic)Akk,AkkermansiaAL,Allicin (mainly Garlic)almon,almonertinibAV,Aloe veraaLinA,alpha Linolenic acidALA,Alpha-Lipoic-AcidAlum,AluminumAMQ,AmodiaquineAnd,AndrographisACNs,AnthocyaninsantiOx,Anti-oxidantsAnzaroot,Anzaroot, Astragalus fasciculifolius BiossApi,Apigenin (mainly Parsley)AG,ArctigeninAroma,AromatherapyATO,Arsenic trioxideART/DHA,ArtemisininAP,Ascorbyl PalmitateAsh,Ashwagandha(Withaferin A)ASA,Aspirin -acetylsalicylic acidASTX,AstaxanthinAS,AstragalusATV,AtorvastatinAur,AuranofinBM,Bacopa monnieriBa,BaicaleinBA,Baicalinbemp,bempedoic acidBaP,benzo(a)pyreneBBM,BerbamineBBR,BerberinebetaCar,beta-carotene(VitA)B-Gluc,beta-glucansBetA,Betulinic acidBEV,Bevacizumab (brand Avastin)Bical,BicalutamideHCO3,BicarbonateBif,BifidobacteriumBCA,Biochanin ABP,Black phosphorusborn,borneolBor,BoronBTZ,BortezomibBos,Boswellia (frankincense)BML,BromelainBJ,Brucea javanicaBRU,brusatolBrut,BruteridinBF,BufalinBA,ButyrateCA,Caffeic acidCaff,CaffeineCalc,CalciumCRMs,Calorie Restriction MimeticsCPT,CamptothecinCBC,CannabichromeneCBD,CannabidiolCBDA,cannabidiolic acidcapec,capecitabineCAP,Capsaicincarbop,carboplatinCA,Carnosic acidCarno,CarnosineCAR,CarvacrolCats,Cat’s ClawCatechins,CatechinsCela,CelastrolCEL,CelecoxibCET,cetuximabCDT,chemodynamic therapyChemo,ChemotherapyChit,chitosanCGA,Chlorogenic acidCHL,ChlorophyllinCHOC,ChocolateChol,CholineCHr,ChrysinCin,CinnamonCisplatin,CisplatinCitrate,Citric AcidCoQ10,Coenzyme Q10Cu,Copper and Cu NanoParticlexCroc,CrocetinCuc,CucurbitacinCUR,CurcuminCUSP9,CUSP9CP,CyclopamineCBC/D,Cynanbungeigenin C (CBC) and D (CBD)Cyste,CysteamineDL,D-limoneneDand,Dandelion RootDAS,DasatinibDFE,Date Fruit ExtractDeg,DeguelinAnamu,dibenzyl trisulphide(DTS) from AnamuDCA,DichloroacetateDAP,Dichloroacetophenone(2,2-)Dicl,DiclofenacdietF,diet Fermented FoodsdietFMD,diet FMD Fasting Mimicking DietdietKeto,diet KetogenicdietMet,diet Methionine-Restricted DietdietP,diet Plant baseddietSTF,diet Short Term FastingdietMed,dietMediterraneanDHCA,Dihydrocaffeic AcidDSMO,Dimethyl SulfoxideDipy,DipyridamoleDSF,Disulfiramdocx,DocetaxelDHA,Docosahexaenoic AciddoxoR,doxorubicinEch,EchinaceaEGCG,EGCG (Epigallocatechin Gallate)EPA,eicosapentaenoic acidEP,Electrical PulsesEA,Ellagic acidRF,EMFEMD,EmodinMS-275,entinostatEPI,epirubicinerastin,erastinEst,EstrogenEDTA,ethylene diamine tetraacetic acidEDM,EvodiamineEx,ExerciseFenb,FenbendazoleFA,Ferulic acidFer,ferumoxytolFIS,FisetinFlav,flavonoidsFLS,Flickering Light StimulationFA,Folic AcidForm,FormononetinF,FucoidanGala,GalantamineGA,Gallic acidGallo,GalloflavinGamB,Gambogic AcidGABA,Gamma-aminobutyric acidGAR,GarcinolGB,gefitinib, erlotinibGEM,Gemcitabine (Gemzar)GEN,Genistein (soy isoflavone)Ger,GermacranolideGE,GermaniumGI,Ginger/6-Shogaol/GingerolGb,Ginkgo bilobaGins,GinsengGlaB,Glabrescione BGluc,GlucoseGlucDep,glucose deprivationGSH,GlutathioneGoldNP,Gold NanoParticlesGos,GossypolGe,Grapeseed extractGra,GraviolaHne,Helleborus niger extracts – Christmas RoseHibSad,Hibiscus sabdariffaHOO,High-Ozonide OilHNK,HonokiolHops,Hops (Humulus lupulus)HRT,Hormone replacement therapyHup,Huperzine A/Huperzia serrataH2,Hydrogen GasH2S,hydrogen sulfideHCQ,hydroxychloroquineHCAs,Hydroxycinnamic-acidHCA,HydroxyCitric AcidHTyr,HydroxytyrosolHT,HydroxyTyrosolHP,HyperosideHPT,HyperthermiaIMA,imatinibimmuno,immunotherapyI3C,Indole-3-carbinolInA,Inoscavin AIns,InositolIP,Inulin Prebioticiod,iodineIP6,IP6 (Inosital 1,2,3,4,5,6-hexakisphosphate)lpi,ipilimumabCPT-11,irinotecanFe,IronisoFl,isoflavonesitraC,itraconazoleIVM,IvermectinJG,JugloneKaempF,KaempferolL-A,L-AlinineL-Orn,L-ornithineLA,LactobacillusLF,LactoferrinLae,Laetrile B17 Amygdalinlamb,lambertianic acidLapC,LapacholLap,LapatinibLas,LasiodinLEC,LecithinLE,Licoricelign,lignansLip,Lipoic acidLDN,low dose naltrexoneLut,LuteinLT,LuteolinLyco,LycopeneMg,MagnesiumMFrot,Magnetic Field RotatingMF,Magnetic FieldsMNPs,magnetic nanoparticlesMAG,MagnololMatr,MatrineMCT,MCToilmeben,mebendazoleMEL,MelatoninMel,MelitidinMET,MetforminMTX,methotrexateMeJa,Methyl JasmonateM-Blu,Methylene blueMGO,MethylglyoxalMeSA,methylseleninic acidMSM,MethylsulfonylmethanemetroC,metronomic chemoMT,MistletoeMCP,Modified Citrus PectinMoringa,Moringa oleiferaMushCha,Mushroom ChagamushLions,Mushroom Lion’s ManeMushMait,Mushroom MaitakeMushPL,Mushroom Phellinus. linteusMushReishi,Mushroom ReishiMushShi,Mushroom Shiitake, AHCCmushTT,mushroom Turkey TailMyr,MyricetinMyrrh,MyrrhNAC,N-Acetyl-CysteineNarG,NaringinNRF,nelfinavir/ViraceptNCL,Niclosamide (Niclocide)NAD,nicotinamide adenine dinucleotideNimb,NimbolideNIV,nivolumabNos,NoscapineOctr,octreotideOleic Acid,Oleic AcidOLEC,OleocanthalOLE,OleuropeinOlive Oil,Olive OilOLST,OrlistatOA,Oroxylin AOA,Oroxylin-AOsi,OsimertinibOXA,OxaliplatinOAA,oxaloacetateOxy,Oxygen, HyperbaricPA,Pachymic acidPacT,PaclitaxelPap,papainPart,ParthenolidePawPaw,Paw PawPem,pembrolizumabP,PeppermintPer,PerillapH-AT,pH-Alkalization TherapyPEITC,Phenethyl isothiocyanatePB,PhenylbutyratePS,PhosphatidylserinePDT,Photodynamic TherapyPFB,Physalin F & BPI,PiperinePL,PiperlonguminePIT,PitavastatinPlum,PlumbaginPEG,polyethylene glycolK+,PotassiumPreB,PrebioticPACs,ProanthocyanidinsProBio,probioticsPBG,Propolis -bee gluePG,Propyl gallatePTS,PterostilbenePurp,PurpuronePhen,PXD, phenoxodiolQC,QuercetinRF,Radio FrequencyRad,Radiotherapy/RadiationRalox,raloxifenRAPA,RapamycinRSL3,Ras-selective lethal 3RSQ,ResiquimodRES,ResveratrolRiv,RivastigmineRosA,Rosmarinic acidRT,RutinSAMe,S-adenosyl-L-methionineSB,Saccharomyces boulardiiSY,Safflower yellowSS,Saikosaponin B1 and DSal,salinomycinSM,Salvia miltiorrhizaSage,Salvia officinalisSANG,SanguinarineSco,ScoulerineSelenate,SelenateSel,SeleniteSe,SeleniumSeMet,selenomethioninesericin,sericin5HT,Serotonin, 5-hydroxytryptamineSesame,Sesame seeds and OilShank,ShankhpushpiSK,ShikoninFulvicA,Shilajit/Fulvic AcidGSL,Siegesbeckia glabrescensSilicon,Silicic AcidSNP,Silver-NanoParticlesSIL,Silymarin (Milk Thistle) silibininSIM,SimvastatinSDT,SonoDynamic Therapy UltraSoundSRF,Sorafenib (brand name Nexavar)Sper,SpermidineSqu,Squalenestatins,statinsSulfas,SulfasalazineSFN,Sulforaphane (mainly Broccoli)SNT,sunitinibSuD,Sutherlandioside DTam,tamoxifenTaur,TaurineTMZ,temozolomideTF,TheaflavinTb,TheobromineTV,Thymol-Thymus vulgarisTQ,ThymoquinoneTC,Tinospora CordifoliaTiO2,Titanium DioxideTomatine,TomatineTACE,Transarterial ChemoembolizationTras,TrastuzumabTSA,Trichostatin ATrip,triptolideTu,TulsiTTT,Tumor Treating FieldsUkrain,Ukrainurea,ureaUro,UrolithinUA,Ursolic acidVem,verapamilVitA,RetA,Vitamin A, Retinoic AcidVitB1/Thiamine,Vitamin B1/ThiamineVitB12,Vitamin B12VitB2,Vitamin B2,RiboflavinVitB3,Vitamin B3,NiacinVitB5,Vitamin B5,Pantothenic AcidVitB6,Vitamin B6,pyridoxineVitC,Vitamin C (Ascorbic Acid)VitD3,Vitamin D3VitE,Vitamin EVitK2,Vitamin K2VitK3,VitK3,menadioneSAHA,VorinostatWBV,Whole Body VibrationWog,WogoninWor,Woreninewortm,wortmanninXyl,XylitolZeax,ZeaxanthinZeo,ZeoliteZER,ZerumboneZ,ZincZO,Zinc Oxideβ�Ele,β�ElemeneGLA,γ-linolenic acid (Borage Oil)γ-Toc,γ-Tocotrienol	Syn4	,2DG,2-DeoxyGlucose3BP,3-bromopyruvate5-ALA,5-Aminolevulinic acid5-FU,5-fluorouracil5-HTP,5-Hydroxytryptophanacet,acetaminophenacetaz,acetazolamideALC,Acetyl-l-carnitineAco,Acoschimperoside P, 2’-acetateAdag,AdagrasibTFdiG,Aflavin-3,3′-digallateATAGJ,Ai-Tong-An-Gao-JiAjoene,Ajoene (compound of Garlic)Akk,AkkermansiaAL,Allicin (mainly Garlic)almon,almonertinibAV,Aloe veraaLinA,alpha Linolenic acidALA,Alpha-Lipoic-AcidAlum,AluminumAMQ,AmodiaquineAnd,AndrographisACNs,AnthocyaninsantiOx,Anti-oxidantsAnzaroot,Anzaroot, Astragalus fasciculifolius BiossApi,Apigenin (mainly Parsley)AG,ArctigeninAroma,AromatherapyATO,Arsenic trioxideART/DHA,ArtemisininAP,Ascorbyl PalmitateAsh,Ashwagandha(Withaferin A)ASA,Aspirin -acetylsalicylic acidASTX,AstaxanthinAS,AstragalusATV,AtorvastatinAur,AuranofinBM,Bacopa monnieriBa,BaicaleinBA,Baicalinbemp,bempedoic acidBaP,benzo(a)pyreneBBM,BerbamineBBR,BerberinebetaCar,beta-carotene(VitA)B-Gluc,beta-glucansBetA,Betulinic acidBEV,Bevacizumab (brand Avastin)Bical,BicalutamideHCO3,BicarbonateBif,BifidobacteriumBCA,Biochanin ABP,Black phosphorusborn,borneolBor,BoronBTZ,BortezomibBos,Boswellia (frankincense)BML,BromelainBJ,Brucea javanicaBRU,brusatolBrut,BruteridinBF,BufalinBA,ButyrateCA,Caffeic acidCaff,CaffeineCalc,CalciumCRMs,Calorie Restriction MimeticsCPT,CamptothecinCBC,CannabichromeneCBD,CannabidiolCBDA,cannabidiolic acidcapec,capecitabineCAP,Capsaicincarbop,carboplatinCA,Carnosic acidCarno,CarnosineCAR,CarvacrolCats,Cat’s ClawCatechins,CatechinsCela,CelastrolCEL,CelecoxibCET,cetuximabCDT,chemodynamic therapyChemo,ChemotherapyChit,chitosanCGA,Chlorogenic acidCHL,ChlorophyllinCHOC,ChocolateChol,CholineCHr,ChrysinCin,CinnamonCisplatin,CisplatinCitrate,Citric AcidCoQ10,Coenzyme Q10Cu,Copper and Cu NanoParticlexCroc,CrocetinCuc,CucurbitacinCUR,CurcuminCUSP9,CUSP9CP,CyclopamineCBC/D,Cynanbungeigenin C (CBC) and D (CBD)Cyste,CysteamineDL,D-limoneneDand,Dandelion RootDAS,DasatinibDFE,Date Fruit ExtractDeg,DeguelinAnamu,dibenzyl trisulphide(DTS) from AnamuDCA,DichloroacetateDAP,Dichloroacetophenone(2,2-)Dicl,DiclofenacdietF,diet Fermented FoodsdietFMD,diet FMD Fasting Mimicking DietdietKeto,diet KetogenicdietMet,diet Methionine-Restricted DietdietP,diet Plant baseddietSTF,diet Short Term FastingdietMed,dietMediterraneanDHCA,Dihydrocaffeic AcidDSMO,Dimethyl SulfoxideDipy,DipyridamoleDSF,Disulfiramdocx,DocetaxelDHA,Docosahexaenoic AciddoxoR,doxorubicinEch,EchinaceaEGCG,EGCG (Epigallocatechin Gallate)EPA,eicosapentaenoic acidEP,Electrical PulsesEA,Ellagic acidRF,EMFEMD,EmodinMS-275,entinostatEPI,epirubicinerastin,erastinEst,EstrogenEDTA,ethylene diamine tetraacetic acidEDM,EvodiamineEx,ExerciseFenb,FenbendazoleFA,Ferulic acidFer,ferumoxytolFIS,FisetinFlav,flavonoidsFLS,Flickering Light StimulationFA,Folic AcidForm,FormononetinF,FucoidanGala,GalantamineGA,Gallic acidGallo,GalloflavinGamB,Gambogic AcidGABA,Gamma-aminobutyric acidGAR,GarcinolGB,gefitinib, erlotinibGEM,Gemcitabine (Gemzar)GEN,Genistein (soy isoflavone)Ger,GermacranolideGE,GermaniumGI,Ginger/6-Shogaol/GingerolGb,Ginkgo bilobaGins,GinsengGlaB,Glabrescione BGluc,GlucoseGlucDep,glucose deprivationGSH,GlutathioneGoldNP,Gold NanoParticlesGos,GossypolGe,Grapeseed extractGra,GraviolaHne,Helleborus niger extracts – Christmas RoseHibSad,Hibiscus sabdariffaHOO,High-Ozonide OilHNK,HonokiolHops,Hops (Humulus lupulus)HRT,Hormone replacement therapyHup,Huperzine A/Huperzia serrataH2,Hydrogen GasH2S,hydrogen sulfideHCQ,hydroxychloroquineHCAs,Hydroxycinnamic-acidHCA,HydroxyCitric AcidHTyr,HydroxytyrosolHT,HydroxyTyrosolHP,HyperosideHPT,HyperthermiaIMA,imatinibimmuno,immunotherapyI3C,Indole-3-carbinolInA,Inoscavin AIns,InositolIP,Inulin Prebioticiod,iodineIP6,IP6 (Inosital 1,2,3,4,5,6-hexakisphosphate)lpi,ipilimumabCPT-11,irinotecanFe,IronisoFl,isoflavonesitraC,itraconazoleIVM,IvermectinJG,JugloneKaempF,KaempferolL-A,L-AlinineL-Orn,L-ornithineLA,LactobacillusLF,LactoferrinLae,Laetrile B17 Amygdalinlamb,lambertianic acidLapC,LapacholLap,LapatinibLas,LasiodinLEC,LecithinLE,Licoricelign,lignansLip,Lipoic acidLDN,low dose naltrexoneLut,LuteinLT,LuteolinLyco,LycopeneMg,MagnesiumMFrot,Magnetic Field RotatingMF,Magnetic FieldsMNPs,magnetic nanoparticlesMAG,MagnololMatr,MatrineMCT,MCToilmeben,mebendazoleMEL,MelatoninMel,MelitidinMET,MetforminMTX,methotrexateMeJa,Methyl JasmonateM-Blu,Methylene blueMGO,MethylglyoxalMeSA,methylseleninic acidMSM,MethylsulfonylmethanemetroC,metronomic chemoMT,MistletoeMCP,Modified Citrus PectinMoringa,Moringa oleiferaMushCha,Mushroom ChagamushLions,Mushroom Lion’s ManeMushMait,Mushroom MaitakeMushPL,Mushroom Phellinus. linteusMushReishi,Mushroom ReishiMushShi,Mushroom Shiitake, AHCCmushTT,mushroom Turkey TailMyr,MyricetinMyrrh,MyrrhNAC,N-Acetyl-CysteineNarG,NaringinNRF,nelfinavir/ViraceptNCL,Niclosamide (Niclocide)NAD,nicotinamide adenine dinucleotideNimb,NimbolideNIV,nivolumabNos,NoscapineOctr,octreotideOleic Acid,Oleic AcidOLEC,OleocanthalOLE,OleuropeinOlive Oil,Olive OilOLST,OrlistatOA,Oroxylin AOA,Oroxylin-AOsi,OsimertinibOXA,OxaliplatinOAA,oxaloacetateOxy,Oxygen, HyperbaricPA,Pachymic acidPacT,PaclitaxelPap,papainPart,ParthenolidePawPaw,Paw PawPem,pembrolizumabP,PeppermintPer,PerillapH-AT,pH-Alkalization TherapyPEITC,Phenethyl isothiocyanatePB,PhenylbutyratePS,PhosphatidylserinePDT,Photodynamic TherapyPFB,Physalin F & BPI,PiperinePL,PiperlonguminePIT,PitavastatinPlum,PlumbaginPEG,polyethylene glycolK+,PotassiumPreB,PrebioticPACs,ProanthocyanidinsProBio,probioticsPBG,Propolis -bee gluePG,Propyl gallatePTS,PterostilbenePurp,PurpuronePhen,PXD, phenoxodiolQC,QuercetinRF,Radio FrequencyRad,Radiotherapy/RadiationRalox,raloxifenRAPA,RapamycinRSL3,Ras-selective lethal 3RSQ,ResiquimodRES,ResveratrolRiv,RivastigmineRosA,Rosmarinic acidRT,RutinSAMe,S-adenosyl-L-methionineSB,Saccharomyces boulardiiSY,Safflower yellowSS,Saikosaponin B1 and DSal,salinomycinSM,Salvia miltiorrhizaSage,Salvia officinalisSANG,SanguinarineSco,ScoulerineSelenate,SelenateSel,SeleniteSe,SeleniumSeMet,selenomethioninesericin,sericin5HT,Serotonin, 5-hydroxytryptamineSesame,Sesame seeds and OilShank,ShankhpushpiSK,ShikoninFulvicA,Shilajit/Fulvic AcidGSL,Siegesbeckia glabrescensSilicon,Silicic AcidSNP,Silver-NanoParticlesSIL,Silymarin (Milk Thistle) silibininSIM,SimvastatinSDT,SonoDynamic Therapy UltraSoundSRF,Sorafenib (brand name Nexavar)Sper,SpermidineSqu,Squalenestatins,statinsSulfas,SulfasalazineSFN,Sulforaphane (mainly Broccoli)SNT,sunitinibSuD,Sutherlandioside DTam,tamoxifenTaur,TaurineTMZ,temozolomideTF,TheaflavinTb,TheobromineTV,Thymol-Thymus vulgarisTQ,ThymoquinoneTC,Tinospora CordifoliaTiO2,Titanium DioxideTomatine,TomatineTACE,Transarterial ChemoembolizationTras,TrastuzumabTSA,Trichostatin ATrip,triptolideTu,TulsiTTT,Tumor Treating FieldsUkrain,Ukrainurea,ureaUro,UrolithinUA,Ursolic acidVem,verapamilVitA,RetA,Vitamin A, Retinoic AcidVitB1/Thiamine,Vitamin B1/ThiamineVitB12,Vitamin B12VitB2,Vitamin B2,RiboflavinVitB3,Vitamin B3,NiacinVitB5,Vitamin B5,Pantothenic AcidVitB6,Vitamin B6,pyridoxineVitC,Vitamin C (Ascorbic Acid)VitD3,Vitamin D3VitE,Vitamin EVitK2,Vitamin K2VitK3,VitK3,menadioneSAHA,VorinostatWBV,Whole Body VibrationWog,WogoninWor,Woreninewortm,wortmanninXyl,XylitolZeax,ZeaxanthinZeo,ZeoliteZER,ZerumboneZ,ZincZO,Zinc Oxideβ�Ele,β�ElemeneGLA,γ-linolenic acid (Borage Oil)γ-Toc,γ-Tocotrienol

Curcumin, a polyphenolic compound derived from Curcuma longa, exhibits significant therapeutic potential in cancer management. This review explores curcumin’s mechanisms of action, the challenges related to its bioavailability, and its enhancement through modern technology and approaches. Curcumin demonstrates strong antioxidant and anti-inflammatory properties, contributing to its ability to neutralize free radicals and inhibit inflammatory mediators. Its anticancer effects are mediated by in ...

PMID	year	Title	Author	Link
PMC11275093	2024	The Bright Side of Curcumin: A Narrative Review of Its Therapeutic Potential in Cancer Management	Andrea Amaroli	https://pmc.ncbi.nlm.nih.gov/articles/PMC11275093/	Link

Model	Illness	Cell Line	Dosage	IC50	Notes
NAin-vitroin-vivovitro+vivoHumanAnalysisReviewex-vivoCase ReportTrialStudy	0-Reserved,ReseACC,Adenoid Cysadrenal,AdrenalALS,AmyotrophicAML,Acute MyeloBC,Breast CanceBCC,Basal Cell Bladder,BladderBrCC,Bronchial CardioV,CardiovCCA,Bile Duct CCerv,Cervical CChon,ChondrosarCLL,Chronic LymColon,Colon CanCRC,Colorectal EC,Endometrial Endo,EndometrioEOC,Epithelial ESCC,OesophageafibroS,FibrosarGall,GallbladdeGBM,GlioblastomGC,Gastric AdenGI,GastrointestHCC,HepatocelluHepat,HepatomaHNSCC,Head and Kidney,Kidney (Laryn,LaryngealLiver,Liver CanLung,Lung Cancelymphoma,LymphoMB,MedulloblastMelanoma,MelanoMG,Malignant GlMM,Malignant MeNA,Not Availablneuroblastoma,NNMSC,Non MelanoNor,Normal HealNPC,NasopharyngNSCLC,Non-smallOral,OralOS,OsteosarcomaOvarian,OvarianPC,Pancreatic CPca,Prostate CaPerC,PeritonealRCC,Renal cell RPE,Retinal Pigsarcoma,SarcomaSCC,Squamous CeSchw,SchwannomaTesti,TesticulaThyroid,ThyroidTLS,Tumor LysisTong,TongueUEC,Uterine EndVar,Various CanAD,Alzheimer's AKI,Acute KidneAlcohol,AlcoholAMD,Age-RelatedArthritis,Arthrasthmatic,AsthmAutism,AutismBPH,Benign ProsCF,Cystic FibroCKD,Chronic KidCol,ColitisCovid,CovidCSCs,Cancer SteDiabetic,DiabetHD,Huntingtonâ€Heart,Heart DisIBD,InflammatorInf,InfectionLiverDam,Liver Mal,MalariaMS,Multiple SclObesity,ObesityostP,OsteoporosPark,Parkinson'PSA,PsoriasisSepsis,SepsisStroke,CerebralUTI,Urinary TraVit,VitiligoWounds,Wounds	1-,Nor1321N1 ,Nor143B,OS2-,Var22Rv1,Pca253J,Bladder3T3,Nor402,lymphoma4T1,BC5637,Bladder769-P,RCC786-O,Kidney8505C,ThyroidA172,GBMA2058,MelanomaA2780S,MelanomaA375,MelanomaA431,MelanomaA498,RCCA549,LungACC-M,adrenalACHN,KidneyAGS,GCALVA-41,PcaAMGM,GBMAMJ13,AMLAML12 ,LiverAN3CA,EndoAPL NB4,AMLARPE-19,NAAsPC-1,PCAU-565,BCB16-BL6,MelanomB16-F10,MelanomBcap37,BCBCPAP,ThyroidBEAS-2B,NorBel-7402,LiverBel7,lymphomaBGC-823,GCBPH1,PCBT20,BCBT474,BCBT549,BCBV2,NorBxpc-3,PCC2C12,NorC33A,CervC3H10T1/2,NAC4-2B,PcaC6,GBMC8161,MelanomaCa9-22,SCCCaco-2,ColonCAF,VarCaki-1,KidneyCAL-62,ThyroidCAL27,SCCCAL33,HNSCCCAL51,BCCalu-1,LungCalu-6,LungCaOV3,OvarianCapan1,PCCC531,CRCCCD-18Co,NorCCD19,NorCCD841,NorCCl233,LungCD133+,PCCD24+,PcaCD44+,PCCEM,0-ReservedCNE1,NPCCNE2,NPCCOLO205,CRCCOLO357,PCcolon26,ColonCRL-7891,LungCT26,ColonCV1,NorCX-1,CRCD407,RPEDAOY,GCDIPG,GBMDLD1,CRCDMS114,LungDU145,PcaE0771,BCE18,NorEAhy926,LungEC9706,ESCCEca109,ESCCECV304,NorEL4,NorEMN21,EndoEMN8,EndoEMT6,BCES-2,OvarianESA+,PCF344,VarF9,TestiFaDu,LarynFaO,HepatFF95,NorFHC,NorFTC-133,ThyroidFTC-133,ThyroidG361,MelanomaGBC-SD,GallGBM,GBMGBM115,GBMGBM8401,GBMGCSCs,GCGES-1,NorGL-15,GBMGL26,GBMglial,NorGM05757 ,NorGP-293,NorH1299,LungH146,LungH157,LungH1650,LungH1792 ,LungH1975,LungH2009,LungH2030,LungH226,SCCH23,LungH2452,MMH292,LungH295R,adrenalH385,LungH4,NorH446,LungH460,LungH4IIE,LiverH6c7,NorH720,BrCCH727,BrCCH9c2 ,NorHaCaT,NorHBE4-E6/E7,NorHBL ,lymphomaHBL-100,NorHBMECs,NorHC11,NorHCC-38,BCHCC1937,BCHCC827,LungHCC9810,HCCHCCLM3,HCCHCE-2,NorHCEC 1CT,NorHCT116,CRCHCT15,ColonHCT8,CRCHDFa,NorHEC1B,ECHEI-OC1,NorHEI193,NorHEK293,NorHeLa,CervHEp2,LarynHep3B,LiverHepaRG ,NorHepG2,LiverHepG3,LiverhESC,NorHet-1A,NorhFOB1.19,NorHGC27,GCHK-2,NorHL-60,AMLHL7702,NorHMC1,0-ReservedHMC3,MelanomaHMEC,NorHMrSV5 ,NorHMVEC-dLy,NorHN30,HNSCCHN5 ,HNSCCHN8,neuroblastoHNK,NAHNPSC,NorHO-8910,OvarianHONE1,NPCHPAECs,NorHPDE-6,NorHPNE,NorHs294T,MelanomaHS587T,BCHS68,NorHs683,GBMHs766t,PCHSC-T6,NorHSC2,OralHSC3,OralHSC4,SCCHT-29,CRCHT1080,IBDHT22,NorHT29,ColonHTB-22,BladderHTB-35,CervHTB94,ChonHTC15,LiverhTERT-HPNE,NorHTH-83,ThyroidHU02,NorHuCCT1,CCAHuH28,CCAHUH7,LiverHuT78,lymphomaHUVECs,NorIB3-1,CFIGROV1,OvarianIHH4,ThyroidIMR32,GBMIMR90,NAIOSE364,NorIPEC-J2,NorISH,ECJ82,BladderJB6,NorJCA-1,PcaJK,0-ReservedJPL119,lymphomaJurkat,AMLK1,ThyroidK562,AMLKAIMRC1,BCKB,OralKG-1 ,AMLKGN,OvarianKLE,EndoKON,neuroblastoKP2,PCKYSE-30,ESCCKYSE-510,ESCCKYSE150,SCCKYSE170,ESCCKYSE450,SCCL02,NorL132,LungL428,lymphomaL929,NorLAPC-4,PcaLGR5,NALL/2 (LLC1),LunLLC1,LungLM8,OSLN-18,GBMLN229,GBMLNCaP,PcaLNM35,LungLoVo,CRCLS1034,CRCLS174T,CRCLU99,LungM059K,GBMM146L,ADMBT-2,BladderMC38,ColonMCF-7 ,BCMCF10 ,NorMCF12A,NorMDA-MB-231,BCMDA-MB-361,BCMDA-MB-435,BCMDA-MB-453,BCMDA-MB-468,BCMDAH-2774,OvariMEF,NormESC,NorMeT5A,NorMG63,OSMGC803,BCMH-S,NorMHCC-97H,HCCMIA PaCa-2,PCMIHA,NorMKN-28,GCMKN45,GCMM.1S,MelanomaMPC5,NorMRC-5,NorMS-1,PCMSTO-211H,MMN9,NorNA,NANCI-H441,LungNCI-H929 ,MelanNCI-N87,GCNCIH1299,LungNCIH23,LungNCM460,NorNG108-15,NorNHEKn ,NorNIH-3T3,NANOZ,GallNRK52E,NorOS-RC-2,NAOV-MZ-6,OvarianOV1369,OvarianOV1946,OvarianOV7 ,OvarianOV90,OvarianOVCAR-3,OvarianPA1,OvarianPanc02,PCPANC1,PCPanCSC,PCPATU-8988,PCPC12,NorPC3,PcaPC9,LungpCSCs ,PcaPECs,NAPEL,lymphomaPHEO ,adrenalPLB-985,AMLPNT1A,NorPrEC,NAPrEC,PcaPWR-1E,NorQGY-7703,HCCRAW264.7,NorRCC4 ,RCCREN,RCCRKO,CRCRM-1,PcaRPE-1,NorRPMI-7951,MelanRPMI-8226,MelanRT112,BladderRT4,BladderRWPE-1,NorS180,sarcomaSALTO,BCSaOS2,OSSCC-154,SCCSCC15 ,SCCSCC25,TongSCC25,SCCSCC4,SCCSCC9,TongSCM1,GCSGC-7901,GCSH-SY5Y,neuroblSiHa,CervSK-HEP-1,adrenaSK-LU-1,LungSK-MEL-28,MelanSK-N-BE,neuroblSK-N-SH,neuroblSkBr3,BCSKM-1,AMLSkMC,NorSKOV3,OvarianSMMC-7721 cell,SNB19,GBMSNU-407,CRCSNU1041,GISNU1076,GISNU16,GCSNU5,GCSNU620,GCSUM159,BCSUNE-1,NPCSV-HUC-1,NorSVGp12,NorSW-620,CRCSW1353,ChonSW48,ColonSW480,ColonSW780 ,BladderT24,CRCT47D,BCT84,ColonT98G,GBMTca8113,TongTCAM-2,TestiTCCSUP,BladderTCO1 ,0-ReserveTCO2,0-ReservedTE1,ESCCTF1,AMLTHESCs ,NorTHP1,AMLTIG-1,NorTK6,lymphomaTM4,NorTMK-1,GCTOV-21G,OvarianTPC-1,ThyroidTRAMP-C1,PcaTSCCa,TongTSGH8301,BladdeTT,ThyroidTUBO,BCTW01,NPCTW06,NPCU118MG,GBMU1285,SCCU251,GBMU266,MelanomaU2OS,OSU343,GBMU373MG,GBMU87MG,GBMU937,lymphomaUM-SCC-1,HNSCCUM-SCC-10B,HNSCUM-SCC-6,HNSCCUMUC3,BladderUTSCC15 ,HNSCCUW-BCC1,NMSCWalker256,BCWI38,NAWM35,MelanomaWM983B,MelanomaWPMY-1,NorWRL68,NorY79,RPEYAMC,NorYD10B,SCCYPEN-1,PcaZR-75-1,BCNA
NAin-vitroin-vivovitro+vivoHumanAnalysisReviewex-vivoCase ReportTrialStudy	0-Reserved,ReseACC,Adenoid Cysadrenal,AdrenalALS,AmyotrophicAML,Acute MyeloBC,Breast CanceBCC,Basal Cell Bladder,BladderBrCC,Bronchial CardioV,CardiovCCA,Bile Duct CCerv,Cervical CChon,ChondrosarCLL,Chronic LymColon,Colon CanCRC,Colorectal EC,Endometrial Endo,EndometrioEOC,Epithelial ESCC,OesophageafibroS,FibrosarGall,GallbladdeGBM,GlioblastomGC,Gastric AdenGI,GastrointestHCC,HepatocelluHepat,HepatomaHNSCC,Head and Kidney,Kidney (Laryn,LaryngealLiver,Liver CanLung,Lung Cancelymphoma,LymphoMB,MedulloblastMelanoma,MelanoMG,Malignant GlMM,Malignant MeNA,Not Availablneuroblastoma,NNMSC,Non MelanoNor,Normal HealNPC,NasopharyngNSCLC,Non-smallOral,OralOS,OsteosarcomaOvarian,OvarianPC,Pancreatic CPca,Prostate CaPerC,PeritonealRCC,Renal cell RPE,Retinal Pigsarcoma,SarcomaSCC,Squamous CeSchw,SchwannomaTesti,TesticulaThyroid,ThyroidTLS,Tumor LysisTong,TongueUEC,Uterine EndVar,Various CanAD,Alzheimer's AKI,Acute KidneAlcohol,AlcoholAMD,Age-RelatedArthritis,Arthrasthmatic,AsthmAutism,AutismBPH,Benign ProsCF,Cystic FibroCKD,Chronic KidCol,ColitisCovid,CovidCSCs,Cancer SteDiabetic,DiabetHD,Huntingtonâ€Heart,Heart DisIBD,InflammatorInf,InfectionLiverDam,Liver Mal,MalariaMS,Multiple SclObesity,ObesityostP,OsteoporosPark,Parkinson'PSA,PsoriasisSepsis,SepsisStroke,CerebralUTI,Urinary TraVit,VitiligoWounds,WoundsNA	1-,Nor1321N1 ,Nor143B,OS2-,Var22Rv1,Pca253J,Bladder3T3,Nor402,lymphoma4T1,BC5637,Bladder769-P,RCC786-O,Kidney8505C,ThyroidA172,GBMA2058,MelanomaA2780S,MelanomaA375,MelanomaA431,MelanomaA498,RCCA549,LungACC-M,adrenalACHN,KidneyAGS,GCALVA-41,PcaAMGM,GBMAMJ13,AMLAML12 ,LiverAN3CA,EndoAPL NB4,AMLARPE-19,NAAsPC-1,PCAU-565,BCB16-BL6,MelanomB16-F10,MelanomBcap37,BCBCPAP,ThyroidBEAS-2B,NorBel-7402,LiverBel7,lymphomaBGC-823,GCBPH1,PCBT20,BCBT474,BCBT549,BCBV2,NorBxpc-3,PCC2C12,NorC33A,CervC3H10T1/2,NAC4-2B,PcaC6,GBMC8161,MelanomaCa9-22,SCCCaco-2,ColonCAF,VarCaki-1,KidneyCAL-62,ThyroidCAL27,SCCCAL33,HNSCCCAL51,BCCalu-1,LungCalu-6,LungCaOV3,OvarianCapan1,PCCC531,CRCCCD-18Co,NorCCD19,NorCCD841,NorCCl233,LungCD133+,PCCD24+,PcaCD44+,PCCEM,0-ReservedCNE1,NPCCNE2,NPCCOLO205,CRCCOLO357,PCcolon26,ColonCRL-7891,LungCT26,ColonCV1,NorCX-1,CRCD407,RPEDAOY,GCDIPG,GBMDLD1,CRCDMS114,LungDU145,PcaE0771,BCE18,NorEAhy926,LungEC9706,ESCCEca109,ESCCECV304,NorEL4,NorEMN21,EndoEMN8,EndoEMT6,BCES-2,OvarianESA+,PCF344,VarF9,TestiFaDu,LarynFaO,HepatFF95,NorFHC,NorFTC-133,ThyroidFTC-133,ThyroidG361,MelanomaGBC-SD,GallGBM,GBMGBM115,GBMGBM8401,GBMGCSCs,GCGES-1,NorGL-15,GBMGL26,GBMglial,NorGM05757 ,NorGP-293,NorH1299,LungH146,LungH157,LungH1650,LungH1792 ,LungH1975,LungH2009,LungH2030,LungH226,SCCH23,LungH2452,MMH292,LungH295R,adrenalH385,LungH4,NorH446,LungH460,LungH4IIE,LiverH6c7,NorH720,BrCCH727,BrCCH9c2 ,NorHaCaT,NorHBE4-E6/E7,NorHBL ,lymphomaHBL-100,NorHBMECs,NorHC11,NorHCC-38,BCHCC1937,BCHCC827,LungHCC9810,HCCHCCLM3,HCCHCE-2,NorHCEC 1CT,NorHCT116,CRCHCT15,ColonHCT8,CRCHDFa,NorHEC1B,ECHEI-OC1,NorHEI193,NorHEK293,NorHeLa,CervHEp2,LarynHep3B,LiverHepaRG ,NorHepG2,LiverHepG3,LiverhESC,NorHet-1A,NorhFOB1.19,NorHGC27,GCHK-2,NorHL-60,AMLHL7702,NorHMC1,0-ReservedHMC3,MelanomaHMEC,NorHMrSV5 ,NorHMVEC-dLy,NorHN30,HNSCCHN5 ,HNSCCHN8,neuroblastoHNK,NAHNPSC,NorHO-8910,OvarianHONE1,NPCHPAECs,NorHPDE-6,NorHPNE,NorHs294T,MelanomaHS587T,BCHS68,NorHs683,GBMHs766t,PCHSC-T6,NorHSC2,OralHSC3,OralHSC4,SCCHT-29,CRCHT1080,IBDHT22,NorHT29,ColonHTB-22,BladderHTB-35,CervHTB94,ChonHTC15,LiverhTERT-HPNE,NorHTH-83,ThyroidHU02,NorHuCCT1,CCAHuH28,CCAHUH7,LiverHuT78,lymphomaHUVECs,NorIB3-1,CFIGROV1,OvarianIHH4,ThyroidIMR32,GBMIMR90,NAIOSE364,NorIPEC-J2,NorISH,ECJ82,BladderJB6,NorJCA-1,PcaJK,0-ReservedJPL119,lymphomaJurkat,AMLK1,ThyroidK562,AMLKAIMRC1,BCKB,OralKG-1 ,AMLKGN,OvarianKLE,EndoKON,neuroblastoKP2,PCKYSE-30,ESCCKYSE-510,ESCCKYSE150,SCCKYSE170,ESCCKYSE450,SCCL02,NorL132,LungL428,lymphomaL929,NorLAPC-4,PcaLGR5,NALL/2 (LLC1),LunLLC1,LungLM8,OSLN-18,GBMLN229,GBMLNCaP,PcaLNM35,LungLoVo,CRCLS1034,CRCLS174T,CRCLU99,LungM059K,GBMM146L,ADMBT-2,BladderMC38,ColonMCF-7 ,BCMCF10 ,NorMCF12A,NorMDA-MB-231,BCMDA-MB-361,BCMDA-MB-435,BCMDA-MB-453,BCMDA-MB-468,BCMDAH-2774,OvariMEF,NormESC,NorMeT5A,NorMG63,OSMGC803,BCMH-S,NorMHCC-97H,HCCMIA PaCa-2,PCMIHA,NorMKN-28,GCMKN45,GCMM.1S,MelanomaMPC5,NorMRC-5,NorMS-1,PCMSTO-211H,MMN9,NorNA,NANCI-H441,LungNCI-H929 ,MelanNCI-N87,GCNCIH1299,LungNCIH23,LungNCM460,NorNG108-15,NorNHEKn ,NorNIH-3T3,NANOZ,GallNRK52E,NorOS-RC-2,NAOV-MZ-6,OvarianOV1369,OvarianOV1946,OvarianOV7 ,OvarianOV90,OvarianOVCAR-3,OvarianPA1,OvarianPanc02,PCPANC1,PCPanCSC,PCPATU-8988,PCPC12,NorPC3,PcaPC9,LungpCSCs ,PcaPECs,NAPEL,lymphomaPHEO ,adrenalPLB-985,AMLPNT1A,NorPrEC,NAPrEC,PcaPWR-1E,NorQGY-7703,HCCRAW264.7,NorRCC4 ,RCCREN,RCCRKO,CRCRM-1,PcaRPE-1,NorRPMI-7951,MelanRPMI-8226,MelanRT112,BladderRT4,BladderRWPE-1,NorS180,sarcomaSALTO,BCSaOS2,OSSCC-154,SCCSCC15 ,SCCSCC25,TongSCC25,SCCSCC4,SCCSCC9,TongSCM1,GCSGC-7901,GCSH-SY5Y,neuroblSiHa,CervSK-HEP-1,adrenaSK-LU-1,LungSK-MEL-28,MelanSK-N-BE,neuroblSK-N-SH,neuroblSkBr3,BCSKM-1,AMLSkMC,NorSKOV3,OvarianSMMC-7721 cell,SNB19,GBMSNU-407,CRCSNU1041,GISNU1076,GISNU16,GCSNU5,GCSNU620,GCSUM159,BCSUNE-1,NPCSV-HUC-1,NorSVGp12,NorSW-620,CRCSW1353,ChonSW48,ColonSW480,ColonSW780 ,BladderT24,CRCT47D,BCT84,ColonT98G,GBMTca8113,TongTCAM-2,TestiTCCSUP,BladderTCO1 ,0-ReserveTCO2,0-ReservedTE1,ESCCTF1,AMLTHESCs ,NorTHP1,AMLTIG-1,NorTK6,lymphomaTM4,NorTMK-1,GCTOV-21G,OvarianTPC-1,ThyroidTRAMP-C1,PcaTSCCa,TongTSGH8301,BladdeTT,ThyroidTUBO,BCTW01,NPCTW06,NPCU118MG,GBMU1285,SCCU251,GBMU266,MelanomaU2OS,OSU343,GBMU373MG,GBMU87MG,GBMU937,lymphomaUM-SCC-1,HNSCCUM-SCC-10B,HNSCUM-SCC-6,HNSCCUMUC3,BladderUTSCC15 ,HNSCCUW-BCC1,NMSCWalker256,BCWI38,NAWM35,MelanomaWM983B,MelanomaWPMY-1,NorWRL68,NorY79,RPEYAMC,NorYD10B,SCCYPEN-1,PcaZR-75-1,BCNA
NAin-vitroin-vivovitro+vivoHumanAnalysisReviewex-vivoCase ReportTrialStudy	0-Reserved,ReseACC,Adenoid Cysadrenal,AdrenalALS,AmyotrophicAML,Acute MyeloBC,Breast CanceBCC,Basal Cell Bladder,BladderBrCC,Bronchial CardioV,CardiovCCA,Bile Duct CCerv,Cervical CChon,ChondrosarCLL,Chronic LymColon,Colon CanCRC,Colorectal EC,Endometrial Endo,EndometrioEOC,Epithelial ESCC,OesophageafibroS,FibrosarGall,GallbladdeGBM,GlioblastomGC,Gastric AdenGI,GastrointestHCC,HepatocelluHepat,HepatomaHNSCC,Head and Kidney,Kidney (Laryn,LaryngealLiver,Liver CanLung,Lung Cancelymphoma,LymphoMB,MedulloblastMelanoma,MelanoMG,Malignant GlMM,Malignant MeNA,Not Availablneuroblastoma,NNMSC,Non MelanoNor,Normal HealNPC,NasopharyngNSCLC,Non-smallOral,OralOS,OsteosarcomaOvarian,OvarianPC,Pancreatic CPca,Prostate CaPerC,PeritonealRCC,Renal cell RPE,Retinal Pigsarcoma,SarcomaSCC,Squamous CeSchw,SchwannomaTesti,TesticulaThyroid,ThyroidTLS,Tumor LysisTong,TongueUEC,Uterine EndVar,Various CanAD,Alzheimer's AKI,Acute KidneAlcohol,AlcoholAMD,Age-RelatedArthritis,Arthrasthmatic,AsthmAutism,AutismBPH,Benign ProsCF,Cystic FibroCKD,Chronic KidCol,ColitisCovid,CovidCSCs,Cancer SteDiabetic,DiabetHD,Huntingtonâ€Heart,Heart DisIBD,InflammatorInf,InfectionLiverDam,Liver Mal,MalariaMS,Multiple SclObesity,ObesityostP,OsteoporosPark,Parkinson'PSA,PsoriasisSepsis,SepsisStroke,CerebralUTI,Urinary TraVit,VitiligoWounds,WoundsNA	1-,Nor1321N1 ,Nor143B,OS2-,Var22Rv1,Pca253J,Bladder3T3,Nor402,lymphoma4T1,BC5637,Bladder769-P,RCC786-O,Kidney8505C,ThyroidA172,GBMA2058,MelanomaA2780S,MelanomaA375,MelanomaA431,MelanomaA498,RCCA549,LungACC-M,adrenalACHN,KidneyAGS,GCALVA-41,PcaAMGM,GBMAMJ13,AMLAML12 ,LiverAN3CA,EndoAPL NB4,AMLARPE-19,NAAsPC-1,PCAU-565,BCB16-BL6,MelanomB16-F10,MelanomBcap37,BCBCPAP,ThyroidBEAS-2B,NorBel-7402,LiverBel7,lymphomaBGC-823,GCBPH1,PCBT20,BCBT474,BCBT549,BCBV2,NorBxpc-3,PCC2C12,NorC33A,CervC3H10T1/2,NAC4-2B,PcaC6,GBMC8161,MelanomaCa9-22,SCCCaco-2,ColonCAF,VarCaki-1,KidneyCAL-62,ThyroidCAL27,SCCCAL33,HNSCCCAL51,BCCalu-1,LungCalu-6,LungCaOV3,OvarianCapan1,PCCC531,CRCCCD-18Co,NorCCD19,NorCCD841,NorCCl233,LungCD133+,PCCD24+,PcaCD44+,PCCEM,0-ReservedCNE1,NPCCNE2,NPCCOLO205,CRCCOLO357,PCcolon26,ColonCRL-7891,LungCT26,ColonCV1,NorCX-1,CRCD407,RPEDAOY,GCDIPG,GBMDLD1,CRCDMS114,LungDU145,PcaE0771,BCE18,NorEAhy926,LungEC9706,ESCCEca109,ESCCECV304,NorEL4,NorEMN21,EndoEMN8,EndoEMT6,BCES-2,OvarianESA+,PCF344,VarF9,TestiFaDu,LarynFaO,HepatFF95,NorFHC,NorFTC-133,ThyroidFTC-133,ThyroidG361,MelanomaGBC-SD,GallGBM,GBMGBM115,GBMGBM8401,GBMGCSCs,GCGES-1,NorGL-15,GBMGL26,GBMglial,NorGM05757 ,NorGP-293,NorH1299,LungH146,LungH157,LungH1650,LungH1792 ,LungH1975,LungH2009,LungH2030,LungH226,SCCH23,LungH2452,MMH292,LungH295R,adrenalH385,LungH4,NorH446,LungH460,LungH4IIE,LiverH6c7,NorH720,BrCCH727,BrCCH9c2 ,NorHaCaT,NorHBE4-E6/E7,NorHBL ,lymphomaHBL-100,NorHBMECs,NorHC11,NorHCC-38,BCHCC1937,BCHCC827,LungHCC9810,HCCHCCLM3,HCCHCE-2,NorHCEC 1CT,NorHCT116,CRCHCT15,ColonHCT8,CRCHDFa,NorHEC1B,ECHEI-OC1,NorHEI193,NorHEK293,NorHeLa,CervHEp2,LarynHep3B,LiverHepaRG ,NorHepG2,LiverHepG3,LiverhESC,NorHet-1A,NorhFOB1.19,NorHGC27,GCHK-2,NorHL-60,AMLHL7702,NorHMC1,0-ReservedHMC3,MelanomaHMEC,NorHMrSV5 ,NorHMVEC-dLy,NorHN30,HNSCCHN5 ,HNSCCHN8,neuroblastoHNK,NAHNPSC,NorHO-8910,OvarianHONE1,NPCHPAECs,NorHPDE-6,NorHPNE,NorHs294T,MelanomaHS587T,BCHS68,NorHs683,GBMHs766t,PCHSC-T6,NorHSC2,OralHSC3,OralHSC4,SCCHT-29,CRCHT1080,IBDHT22,NorHT29,ColonHTB-22,BladderHTB-35,CervHTB94,ChonHTC15,LiverhTERT-HPNE,NorHTH-83,ThyroidHU02,NorHuCCT1,CCAHuH28,CCAHUH7,LiverHuT78,lymphomaHUVECs,NorIB3-1,CFIGROV1,OvarianIHH4,ThyroidIMR32,GBMIMR90,NAIOSE364,NorIPEC-J2,NorISH,ECJ82,BladderJB6,NorJCA-1,PcaJK,0-ReservedJPL119,lymphomaJurkat,AMLK1,ThyroidK562,AMLKAIMRC1,BCKB,OralKG-1 ,AMLKGN,OvarianKLE,EndoKON,neuroblastoKP2,PCKYSE-30,ESCCKYSE-510,ESCCKYSE150,SCCKYSE170,ESCCKYSE450,SCCL02,NorL132,LungL428,lymphomaL929,NorLAPC-4,PcaLGR5,NALL/2 (LLC1),LunLLC1,LungLM8,OSLN-18,GBMLN229,GBMLNCaP,PcaLNM35,LungLoVo,CRCLS1034,CRCLS174T,CRCLU99,LungM059K,GBMM146L,ADMBT-2,BladderMC38,ColonMCF-7 ,BCMCF10 ,NorMCF12A,NorMDA-MB-231,BCMDA-MB-361,BCMDA-MB-435,BCMDA-MB-453,BCMDA-MB-468,BCMDAH-2774,OvariMEF,NormESC,NorMeT5A,NorMG63,OSMGC803,BCMH-S,NorMHCC-97H,HCCMIA PaCa-2,PCMIHA,NorMKN-28,GCMKN45,GCMM.1S,MelanomaMPC5,NorMRC-5,NorMS-1,PCMSTO-211H,MMN9,NorNA,NANCI-H441,LungNCI-H929 ,MelanNCI-N87,GCNCIH1299,LungNCIH23,LungNCM460,NorNG108-15,NorNHEKn ,NorNIH-3T3,NANOZ,GallNRK52E,NorOS-RC-2,NAOV-MZ-6,OvarianOV1369,OvarianOV1946,OvarianOV7 ,OvarianOV90,OvarianOVCAR-3,OvarianPA1,OvarianPanc02,PCPANC1,PCPanCSC,PCPATU-8988,PCPC12,NorPC3,PcaPC9,LungpCSCs ,PcaPECs,NAPEL,lymphomaPHEO ,adrenalPLB-985,AMLPNT1A,NorPrEC,NAPrEC,PcaPWR-1E,NorQGY-7703,HCCRAW264.7,NorRCC4 ,RCCREN,RCCRKO,CRCRM-1,PcaRPE-1,NorRPMI-7951,MelanRPMI-8226,MelanRT112,BladderRT4,BladderRWPE-1,NorS180,sarcomaSALTO,BCSaOS2,OSSCC-154,SCCSCC15 ,SCCSCC25,TongSCC25,SCCSCC4,SCCSCC9,TongSCM1,GCSGC-7901,GCSH-SY5Y,neuroblSiHa,CervSK-HEP-1,adrenaSK-LU-1,LungSK-MEL-28,MelanSK-N-BE,neuroblSK-N-SH,neuroblSkBr3,BCSKM-1,AMLSkMC,NorSKOV3,OvarianSMMC-7721 cell,SNB19,GBMSNU-407,CRCSNU1041,GISNU1076,GISNU16,GCSNU5,GCSNU620,GCSUM159,BCSUNE-1,NPCSV-HUC-1,NorSVGp12,NorSW-620,CRCSW1353,ChonSW48,ColonSW480,ColonSW780 ,BladderT24,CRCT47D,BCT84,ColonT98G,GBMTca8113,TongTCAM-2,TestiTCCSUP,BladderTCO1 ,0-ReserveTCO2,0-ReservedTE1,ESCCTF1,AMLTHESCs ,NorTHP1,AMLTIG-1,NorTK6,lymphomaTM4,NorTMK-1,GCTOV-21G,OvarianTPC-1,ThyroidTRAMP-C1,PcaTSCCa,TongTSGH8301,BladdeTT,ThyroidTUBO,BCTW01,NPCTW06,NPCU118MG,GBMU1285,SCCU251,GBMU266,MelanomaU2OS,OSU343,GBMU373MG,GBMU87MG,GBMU937,lymphomaUM-SCC-1,HNSCCUM-SCC-10B,HNSCUM-SCC-6,HNSCCUMUC3,BladderUTSCC15 ,HNSCCUW-BCC1,NMSCWalker256,BCWI38,NAWM35,MelanomaWM983B,MelanomaWPMY-1,NorWRL68,NorY79,RPEYAMC,NorYD10B,SCCYPEN-1,PcaZR-75-1,BCNA

App	Con	Target/Pathway	State	Eff	Note
CancerNormNorm	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅	Curcumin demonstrates strong antioxidant and anti-inflammatory properties, contributing to its ability to neutralize free radicals and inhibit inflammatory mediators
CancerNormNorm	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormNorm	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅	Its anticancer effects are mediated by inducing apoptosis, inhibiting cell proliferation, and interfering with tumor growth pathways in various colon, pancreatic, and breast cancers
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅	application is limited by its poor bioavailability due to its rapid metabolism and low absorption.
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅	curcumin-loaded hydrogels and nanoparticles, have shown promise in improving curcumin bioavailability and therapeutic efficacy.
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅	Studies have demonstrated that curcumin can suppress the proliferation of cancer cells by interfering with the cell cycle [21,22]
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅	Curcumin enhances the expression of pro-apoptotic proteins such as Bax, Bak, PUMA, Bim, and Noxa and death receptors such as TRAIL-R1/DR4 and TRAIL-R2/DR5
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅	curcumin decreases the levels of anti-apoptotic proteins like Bcl-2, Bcl-XL, survin, and XIAP
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅	This shift in the balance of apoptotic regulators facilitates the release of cytochrome c from mitochondria [33,35] and activates caspases
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅	Curcumin suppresses the activity of key transcription factors like NF-κB, STAT3, and AP-1 and interferes with critical signal transduction pathways such as PI3K/Akt/mTOR and MAPK/ERK.
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅	curcumin inhibits angiogenesis and metastasis by downregulating VEGF, VEGFR2, and matrix metalloproteinases (MMPs).
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅	Epigenetic modifications through the inhibition of DNA methyltransferases (DNMTs) and histone deacetylases (HDACs) further contribute to its anticancer properties.
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅	curcumin-loaded nanoparticles showed significant cytotoxicity in the SCC25, MDA-MB-231, and A549 cell lines, with a decrease in tumor cell proliferation, an increase in ROS, and an increase in apoptosis.	Δ cell
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓NA	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓NA	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓NA	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅
CancerNormCancer	-DTCSh	0-unsued,0-unsued?12LOX,12â€�lipoxygenase↑14-3-3 proteins,14-3-3 proteins↑4-HNE,4‑Hydroxynonenal↑4E-BP1,eukaryotic translation in↓5HT,Serotonin↑5LO,5-lipoxygenase (5-LO)↑67LR,67-kDa laminin receptor↑6PGD,6-phosphogluconate dehydrog↑ABC,ABC transporter↑ABCG2,ATP-binding cassette sub-f↑ABL1,Tyrosine-protein kinase ABL↑Ac-histone H3,Acetylated Histone↓ACAA1,Acetyl-CoA Acyltransferase⇅ACC,Acetyl-CoA Carboxylase↑ACC-α,Acetyl-CoA Carboxylase al↑ACC1,acetylâ€�CoA carboxylase 1↑Acetyl-CoA,Acetyl-CoA?Ach,Acetylcholine↓AChE,acetylcholinesterase↑ACLY,ATP citrate lyase↑ACOX1,Acyl-CoA Oxidase 1↑ACSL1,Acyl-CoA Synthetase Long-C↑ACSL4,Acyl-CoA Synthetase Long-C↑ACSL5,(Acyl-CoA Synthetase Long ↑ACSS2,Acyl-CoA Synthetase Short ↑ACTA2,Actin Alpha Cardiac Muscle↑ACVR1B,activin A receptor, type ⇅ADAM10,A Disintegrin And Metallo↓ADAM17,A Disintegrin and Metallo↑adiP,adiponectin↓ADP:ATP,ADP/ATP ratio↑AEG1,Astrocyte Elevated Gene-1↑AEP,Asparagine Endopeptidase↑AFP,α-fetal protein↑AGEs,Advanced Glycation End Prod↑AGRN,agrin↑AhR,aryl hydrocarbon receptor↑AIF,Apoptosis-Inducing Factor↑AIM2,Absent In Melanoma 2↓AKR1C2,Aldo-keto reductase famil↑Akt,PKB-Protein kinase B↑AKT1,v-akt murine thymoma viral ↑Akt2,RAC-beta serine/threonine-p↑ALAT,ALT, alanine aminotransfera↑Albumin,Albumin↓ALC,absolute lymphocyte count↑ALDH,Aldehyde Dehydrogenase↑ALDH1A1,Aldehyde Dehydrogenase 1↑ALDOA,Aldolase A↑ALDOAiso2,fructose-bisphosphate ↑Alix/AIP‑1,Alix (ALG‑2–int↑ALK,anaplastic lymphoma receptor↑ALP,Alkaline Phosphatase↑AMACR,alpha-methylacyl-CoA racem↑AminoA,Amino Acids↑AMP,Adenosine Monophosphate↑AMPK,adenosine monophosphate-act↓AMPKα,AMP-activated protein kin↓angioG,angiogenesis↑angioS,angiostatin↓annexin II,ANXA2↑AntiAg,Antiplatelet aggregation?AntiAge,Anti-aging↓AntiCan,Anticancer Effect?AntiDiabetic,AntiDiabetic?AntiFungal,AntiFungal?antiNeop,antineoplastic↓antiOx,anti-oxidant activities↑AntiThr,antithrombotic?AntiTum,AntiTumor?AntiViral,AntiViral?ANXA7,annexin A7↓AP-1,Activator protein 1↑APA,autophagosome accumulation↑APAF1,Apoptotic Protease Activat↓APC,adenomatous polyposis coli↓Apoptosis,Apoptosis↓APP,amyloid precursor protein↑Appetite,Appetite?AQPs,Aquaporins↑AR,androgen receptor↑AR-FL,full-length androgen recep↑AR-V7,androgen receptor splice v↑ARE,antioxidant responsive eleme?ARE/EpRE,electrophile response e?ARG,Arginases ARG1/2↑ARID1A,AT rich interactive domaiâ†�ARID1B,AT rich interactive domai⇅ARID2,AT rich interactive domain↓ARNT,aryl hydrocarbon receptor n↑ASC,Apoptosis-associated Speck-l⇅ascitic,ascitic fluid↑ASCT2,ASCT2 glutamine transporte↑ASK1,Apoptosis Signal-regulating↑aSmase,Acid Sphingomyelinase↓AST,Aspartate Aminotransferase↑ASXL1,additional sex combs like ↓ATF2,Activating Transcription Fa↑ATF3,Activating Transcription Fa↑ATF4,Activating Transcription Fa↑ATF6,Activating Transcription Fa↑ATFs,activating transcription fa↑ATG3,Autophagy-related 3↑ATG5,Autophagy-related 5↑ATG7,ATG7⇅ATM,similar to Serine-protein ki↓ATP,Adenosine triphosphate⇅ATP:AMP,ATP:AMP ratioâ†�ATPase,ATPase (Vâ€�ATPase)?ATR,Ataxia-Telangiectasia and Ra↑ATRX,alpha thalassemia/mental re↓autolysosome,autolysosome?autoS,autoschizis?AVOs,Acidic vesicular organelles↓AXIN1,Axis inhibition protein 1↓Axin2,Axis Inhibition Protein 2↑AXL,Anexelekto↑Aβ,Aβ aggregation↑B2M,beta-2-microglobulin⇅BACE,β-site APP-cleaving enzyme↑BACH1,BTB and CNC homology 1↑Bacteria,Effect on Bacteria?BAD,BCL2 associated agonist of c↑Bak,BAK or BAK1↓BAP1,BRCA1 associated protein-1 ↓BAX,Apoptosis regulator BAX↓Bax:Bcl2,Bax:Bcl2 ratio↓BBB,Blood-Brain Barrier∅BCAP,B cell adaptor for phosphat↑BChE,butyrylcholinesterase↑Bcl-2,B-cell CLL/lymphoma 2↑Bcl-xL,Bcl-xL↑BCOR,BCL6 co-repressor↓BCR,Breakpoint Cluster Region?BCR-ABL,BCR-ABL↑BDNF,brain-derived neurotrophic ↓Beclin-1,Beclin-1 (BECN1 gene)↓Bfl-1,Bfl-1 (A1)↑BG,Blood Glucose?BID,BH3 interacting-domain death↓Bil,Bilirubin?BIM,BIM protein (BCL-2 Interacti↓BioAv,bioavailability?BioEnh,bioenhancer?BloodF,Blood Flow?BMAL1,ARNTL⇅BMD,bone mineral density↓BMI1,B cell-specific Moloney mur↑BMP2,Bone Morphogenetic Protein ↑BMP3,Bone Morphogenetic Protein ↓BMPs,Bone morphogenetic protein⇅BNIP3,BCL2/adenovirus E1B intera↑BNP,Brain Natriuretic Peptide↑BOK,Bcl-2-related ovarian killer↓BOLD,Blood-Oxygen-Level-Dependen↓Bone Healing,Bone Healing?BowelM,Regular Bowel Movement?BP,Blood Pressure?BRAF,v-raf murine sarcoma viral ↑BrainVol,Hippocampal Volume↓BRCA1,BReast CAncer gene 1↓BRCA2,BReast CAncer gene 2↓breath,breathing ability?BRG1,Brahma-related gene 1↓Brk/PTK6,Breast Tumor Kinase/Pro↑BTG3,B-cell translocation gene 3↓BUN,blood urea nitrogen↑CA,Carbonic anhydrases↑Ca+2,Calcium Ion Ca+2↑CA125,CA125↑CA19-9,CA 19-9?cachexia,cachexia↑CAFs/TAFs,cancer/tumor-associate↑CAIX,Carbonic Anhydrase IX↑cal2,calpain-2↓Calcium,Calcium mineralization↑CaMKII ,Calcium/Calmodulin-depe↑cAMP,cyclic adenosine monophosph⇅carcinogenesis,carcinogenesis↑CARD11,caspase recruitment domai↑cardioP,cardioProtective∅CardioT,Cardiotoxicity↑CarnA,Carnitine Acyltransferase↑Cartilage,Cartilage↓Casp,caspase?Casp1,Caspase-1↑Casp10,cysteine-aspartic proteas↓Casp12,Caspase-12?Casp2,caspase-2↓Casp3,CPP32, Cysteinyl aspartate↓Casp6,Caspase-6↑Casp7,Caspase-7?Casp8,CASP8, caspase 8, apoptosi?Casp9,Caspase-9↓Catalase,Catalase?Cav1,Caveolin-1?CBL,Casitas B-lineage Lymphoma?CBP,CREB-binding protein↑CC(CDKs/cyclins),Cell cycle (CDK↑CC/Apoptosis,Cell Cycle / Apopto?CCDC150,CCDC150, Coiled-coil dom↑CCL20,Chemokine [C-C motif] liga↑CCR7,C-C chemokine receptor type↑CD11b,CD11b↑CD133,prominin-1↑CD14,CD14↑CD24,CD24?CD25+,IL-2Rα interleukin-2 rec↑CD31,platelet endothelial cell a↑CD34,CD34 transmembrane phosphog↑CD38,CD38 protein↑CD4+,CD4+ T Cells?CD44,CD44↑CD69,CD69?CD8+,CD8+ T cell?CDC16,Cell Division Cycle 16?cDC2,type 2 conventional dendrit?CDC2,cell division cycle 2?CDC25,Cell Division Cycle 25↑Cdc42,Cdc42cdc2↑CDC7,Cell Division Cycle 7↑CDC73,cell division cycle 73, Pa?CDH1,cadherin 1, type 1, E-cadhe↓CDK1,Cyclin-dependent kinase 1↑CDK1/2/5/9,Cyclin-dependent kina↑CDK2,Cyclin-dependent kinase 2↑CDK4,Cyclin-dependent kinase 4↑CDK4/6,CDK4/6↑CDK5,Cyclin-dependent kinase 5↑CDK6,Cyclin-dependent kinase 6↑CDK8,cyclinâ€�dependent kinase 8↑CDKN1C,cyclin-dependent kinase (↓CDKN2A,cyclin-dependent kinase i↓CDX2,Caudal-type homeobox 2↑CEA,Carcinoembryonic antigen↑CEBPA,CCAAT/enhancer binding pro↓CEBPB,CCAAT/enhancerâ€�binding p↑cellD,cell Death?CellMemb,Cellular Membrane alter?cellSen,cellular senescence⇅CentClus,Centrosome clustering↑Ceru,ceruloplasmin↑cFLIP,cellular FLICE-like inhibi↑cFos,cellular Fos↑cGAS–STING,GMP-AMP synthase (c?ChAT,Choline acetyltransferase?ChemChap,chemical chaperones?chemoP,ChemoProtective∅chemoR,chemoresistance↑ChemoSen,chemo-sensitization↓ChemoSideEff,Side Effects of Che↑CHIP,Clonal Hematopoiesis of Ind?CHK1,Checkpoint Kinase 1↑Chk2,Checkpoint Kinase 2↓Chl,chloride↑Choline,Choline↑cholinesterase,cholinesterase↓CholMet,Cholesterol metabolites↑CholSyn,Cholesterol synthesis↑CHOP,GADD153↑ChrMod,Chromatin modification?CIC,capicua homolog (Drosophila)↓CIP2A,Cancerous Inhibitor of Pro↑circ-PRKCA,circular RNA PRKCA↑citrate,citrate levels↓cJun,cellular Transcription fact↑CK2,Casein Kinase 2↑CLDN1,claudin-1↑CLDN2,claudin-2↑CLDN3,claudin‑3↑CLDN5,Claudin-5↑CLOCK,Circadian Locomotor Output↑CLP,bone marrow common lymphoid ↓cMET,cellular hepatocyte growth ↑cMYB,c-MYB↑cMyc,cellular-MYC oncogene↑Cofilin,Cofilin⇅cognitive,cognitive?COL1,Collagen I↑COL1A1,Collagen Type I Alpha 1 C↑COL2A1,COL2A1↑COL3A1,collagen3a↑COL4,Collagen IV alpha chain↑COL9A3,COL9A3↓COMP,Cartilage Oligomeric Matrix↑compI,mitochondrial complex-I⇅compIII,Mitochondrial complex II↑COMT,catechol-O-methyl transfera?Copper,Copper↑CoQ10,coenzyme Q10↓cortisol,cortisol↑COX1,COX-1↑COX2,cycloocygenase-2 (Cox-2) mR↑cPLA2,cytosolic phospholipase A2↑CPT1A,Carnitine Palmitoyltransfe↑CR3,Complement Receptor Type 3⇅creat,creatinine↑CREB,cAMP Response Element Bindi↑CREB2,cAMP response elementâ€�bi⇅CREBBP,CREB binding protein⇅CRLF2,cytokine receptor-like fac↑CRM,Calorie restriction mimetics∅CRM1,Nuclear exporter CRM1↑CRP,C-reactive protein↑CRT,calreticulin↑CSCs,Cancer Stem Cells↑CSCsMark,Cancer Stem Cell Marker↑CSF1R,colony stimulating factor ↑CSR1,Cellular stress response 1?cSrc,cellular Proto-oncogene tyr↑CT-I,Chymotrypsin-like (CT-l) ac↑CTC,Circulating-Tumour-Cells↑CTGF,Connective Tissue Growth Fa↑CTLA-4,Cytotoxic T-Lymphocyte An↑CTNNB1,catenin (cadherin-associa↑CTR1,Copper Transporter 1↑CTSZ,Cathepsin Z?CUL4B,Cullin 4B↑Cupro,Cuproptosis∅CXCc,CXC chemokine family↑CXCL1,CXCL1↑CXCL12,SDF–1↑CXCL9,CXCL9↑CXCR2,CXCR2↑CXCR4,Chemokine Receptor Type 4↑Cyc,Cyclin?cycA1/CCNA1,cyclin A1↑CycB/CCNB1,Cyclin B↑cycD1/CCND1,cyclin D1 pathway↑CycD3,Cyclin D3↑cycE/CCNE,Cyclin E↑cycE1,cyclin E1(CCNE1)↑cycF,CCNF cyclin F↑CYFRA21-1,cytokeratin 19 fragmen↑CYLD,cylindromatosis (turban tum↓CYP11A1,CYP11A1↑CYP17A1,cytochrome P450 CYP17A1↑CYP19,aromatase↑CYP1A1,Cytochrome P450 1A1↑CYP1A2,CYP1A2?CYP1B1,Cytochrome P450 Family 1 ↑CYP27B1,CYP27B1↓CYP2A3/CYP2A6,CYP2A3/CYP2A6↑CYP2C6,CYP2C6?CYP2C9,CYP2C9?CYP2D1,CYP2D1?CYP2E1,cytochrome P450 2E1 (CYP2↑CYP3A2,CYP3A2?CYP3A4,CYP3A4↑Cyt‑c,cyt-c Release into Cytos↓cytoP,cytoprotection?cytoP450,cytochrome P450 (CYP)↑DAXX,death-domain associated pro↓DCells,dendritic Cells↓Dcr,Disturbed circadian rhythms↑decorin,decorin↓DFF45,DNA Fragmentation Factor 4?DGAT1,Diacylglycerol O-acyltrans↑DHCR24,24-Dehydrocholesterol Red⇅DHT,dihydrotestosterone level↑Diablo,Diablo↓Diff,differentiation↓DJ-1,DJ-1↑DLC1,deleted in liver cancer 1↓DLEU1,Deleted in Lymphocytic Leu↑DNA-PK,DNA-dependent protein kin↑DNAdam,DNA damage↑DNAdamC,DNA damage control?DNArepair,DNA repair?DNMT1,DNA (cytosine-5-)-methyltr↑DNMT3A,DNA (cytosine-5-)-methylt↓DNMT3B,Maintenance DNA Methyltra↑DNMTs,DNA methyltransferase↑Dose,Dosage∅DPPH,2,2-diphenyl-1-picrylhydraz?DR4,Death Receptor 4↓DR5,Death receptor 5↑DYRK1A,Dual-specificity tyrosine?E-cadherin,E-cadherin↓E-sel,E-selectin↑E2Fs,E2F family of transcription↑E6,E6↑E7,E7↑ECAR,Extracellular Acidification↑ECM/TCF,Endothelial cell migrati↑EF-1α,elongation factor 1 alpha↑EFEMP,EGF-containing fibulin-lik⇅eff,efficacy∅EGF,Epidermal Growth Factor expr?EGFR,Epidermal Growth Factor Rec↑EGR1,Early Growth Response 1⇅EGR4,Early Growth Response 4⇅eIF2α,Eukaryotic translation in?EIF4E,eukaryotic translation ini↑Eifp,Elevated interstitial fluid↑Elvol3,ELOVL fatty acid elongase?EM,epithelial markers↓EMMPRIN,Extracellular Matrix Met↑EMT,Epithelial-Mesenchymal Trans↑Endoglin,CD105↑Endon,endonuclease⇅ENO1,α-Enolase↑ENO2,Enolase 2↑eNOS,endothelial Nitric Oxide Sy⇅ENOX,enolase↑ENOX2,NADH oxidases↑EP2,Prostaglandin E2 receptor 2↑EP300,E1A binding protein p300↑EP4,Prostaglandin E2 receptor 4↑EpCAM,epithelial Cell Adhesion M↑EphB4,tyrosine kinase EphB4↑EPR,enhanced permeability and re↑ER Stress,endoplasmic reticulum ?ER-α36,estrogen receptor alpha ↑ER(estro),Estrogen receptor↑ERCC1,Excision Repair Cross Comp↑ERK,ERK signaling↑ERK5,extracellular signal-regula↑ERStress,Endoplasmic reticulum s↑ERα/ESR1,Estrogen Receptor alph⇅ERβ,Estrogen receptor beta also↓Estro,Estrogen↑EstroRS/ERS,Estrogen receptor si↑ETC,Electron Transport Chain?EZH2,enhancer of zeste homolog 2↑F-actin,fibrous actin↑FABP4,Fatty acid-binding protein↑FADD,FADD↑FAK,FAK signaling↑FAM123B,family with sequence sim↑FAM72A,FAM72A↑FAO,Fatty Acid Oxidation↑Fap1,PTPN13↑Fas,Fas Death receptor↑fascin,fascin↑FasL,Fas ligand⇅FASN,Fatty acid synthase↑FBI-1,FBI‑1 (Pokemon/ZBTB7A)↑FBP1,fructose-1,6-bisphosphatase↓FBPase,Fructose-1,6-Bisphosphata↓FBXW7,F-box and WD repeat domain↓FDG,F-FDG∅Fenton,Fenton Reaction↑Ferritin,SF serum Ferritin↑Ferroptosis,Ferroptosis?FGF,Fibroblast growth factors↑FGF21,FGF21⇅FGFR1,Fibroblast Growth Factor R↑FGFR2,fibroblast growth factor r↑FGFR3,fibroblast growth factor r↑Fibronectin,Fibronectin↑Fibrosis,Fibrosis↑FKBP5,FK506 binding protein 51↑FLRT2,FLRT2 gene?FLT3,fms-related tyrosine kinase↑FLT4,Fms-related tyrosine kinase↑FOSB,FOSB↓FOSL1,FOSL1 (FRA-1)↑FOXD3,FOXD3↓FOXL2,forkhead box L2↑FOXM1,FOXM1 transcription factor↑FOXO,Forkhead box O↓FOXO1,Forkhead box O1↓FOXO3,Forkhead Box O3↓FOXO4,Forkhead box O 4↓FOXP3,forkhead box P3↑FoxP3+,Forkhead box P3+↑frataxin,frataxin↓FTH1,ferritin heavy chain↑FTL,ferritin light chain↑FTO,Fat mass and obesity-associa↑FUBP1,far upstream element (FUSE↑Furin,Furin↑G6PD,Glucose-6-phosphate dehydro↑G9a,G9a↑GABA,γ-aminobutyric acid↑GADD34,Growth Arrest and DNA Dam↑GADD45A,Growth Arrest and DNA Da↓Galectin-9,Galectin-9⇅GAPDH,Glyceraldehyde-3-phosphate↑GATA1,GATA binding protein 1 (gl⇅GATA2,GATA binding protein 2↑GATA3,GATA binding protein 3?GCLC,Glutamate-Cysteine Ligase, ⇅GCLM,Glutamate-Cysteine Ligase M↑GDF15,Growth differentiation fac↑GDH,Glutamate dehydrogenase↑GFR,glomerular filtration rate↓GIT1,GIT-1 gene?Gli,GLI↑Gli1,glioma-associated oncogene ↑GLI2,GLI2?GLI3,GLI3?GLO-I,glyoxalase I↑GLS,glutaminase↑glucoNG,gluconeogenesis↑glucose,glucose↑GlucoseCon,Glucose Consumption↑glut,glutamine↑GLUT1,Glucose Transporter 1↑GLUT2,Glucose Transporter 2â†�GLUT3,GLUT3↑GLUT4,Glucose Transporter 4↑GlutaM,Glutaminolysis↑GlutMet,Glutamine metabolism↑glyC,glycogen↑Glycolysis,Glycolysis↑GM-CSF,Granulocyte-macrophage co↑GNA11/Gαq,guanine nucleotide bi↑GNAQ,guanine nucleotide binding ↑GNAS,GNAS complex locus↑GNLY,Granulysin⇅GnT-V,N-acetylglucosaminyltransf↑GP1BB,glycoprotein Ib beta subun↑GPI,Glucose-6-Phosphate Isomeras↑GPx,Glutathione peroxidases↑GPx1,Glutathione Peroxidase↑GPx3,Glutathione Peroxidase 3↓GPx4,Glutathione Peroxidase 4↑GPx8,Glutathione Peroxidase 8↑GR,glucocorticoid receptors⇅GranA,granzyme A⇅GranB,Granzyme B⇅GREM1,Gremlin1↑GRP58,GRP58/ERp57↑GRP78/BiP,HSPA5↑GRP94,Glucose-Regulated Protein ↑GS3Kβ,Glycogen Synthase Kinase ⇅GSDMC,Gasdermin C↑GSDMD,gasdermin D↓GSDME,gasdermin E↓GSDME-N,Nâ€�terminal domain of G↓GSH,Glutathione↑GSH/GSSG,GSH/GSSG ratio↑GSKâ€�3β,Glycogen synthase kina⇅GSR,Glutathione Reductase↑GSS,Glutathione Synthetase↑GSSG,oxidized glutathione↓GSTA1,Glutathione S-Transferase ↑GSTP1/GSTÏ€,Glutathione S-transf↑GSTs,Glutathione S-transferases↑GSTZ1,Glutathione S-transferase ⇅GTPBP4,GTP-binding protein 4↑GutMicro,Gut Microbiotaâ†�H19,H19 long non-coding RNA (lnc↑H2O2,Hydrogen peroxide (H2O2)↑H2S,hydrogen sulfide⇅H3,Histone 3↑H3F3A,H3F3A↑H3K18,Histone 3 Lysine 18↑H3K27ac,histone H3 lysine 27 ace↑H4,Histone 4↑Half-Life,Half-Life∅HATs,histone acetyltransferases↑HbA1c,hemoglobin A1c↑HCAR1,Hydroxycarboxylic acid rec↑HDAC,Histone deacetylases↑HDAC1,Histone Deacetylase 1↑HDAC10,HDAC10↑HDAC11,Histone Deacetylase 11⇅HDAC2,Histone Deacetylase 2↑HDAC3,Histone Deacetylase 3↑HDAC4,Histone deacetylases↑HDAC6,HDAC6↑HDAC8,Histone deacetylase 8↑HDL,HDL cholesterol↓Hear,Hearing↓HEC1,highly expressed in cancer ↑HemoG,Hemoglobin↓heparanase,heparan sulfate degra↑hepatoP,L,hepatoprotective↓HER2/EBBR2,Human epidermal growt↑HEY1,Hairy/enhancer-of-split rel↑HGF/c-Met,met proto-oncogene (he↑HH,Hedgehog signaling↑HIF-1,HIF-1 signaling↑Hif1a,HIF1α/HIF1a↑HIF2a,Hypoxia-Inducible Factor 2↑Hippo,Hippo signaling pathway↓HIST1H3B,histone cluster 1, H3j,⇅Histones,Histones?HK1,Hexokinase 1↑HK2,Hexokinase 2↑HLA,Human Leukocyte Antigen (HLA↓HMG-CoA,3â€�hydroxy-3â€�methylgl↑HMGB1,High Mobility Group Box 1↑HMGCR,3-hydroxy-3-methylglutaryl↑HMTs,Histone methyltransferases ↑HNE,4-hydroxynonenal (HNE)↑HNF1A,HNF1 homeobox A↓hnRNPA1,Heterogeneous nuclear ri↑HO-1,HMOX1↑HO-2,HO-2↑homoC,homocysteine↑HR,Homologous recombination⇅HRAS,v-Ha-ras Harvey rat sarcoma↑HRI,Heme-regulated eIF2α kinase⇅hs-CRP,High-sensitivity C-reacti↑Hsc70,Heat Shock Cognate Protein↑HSD17B4,hydroxysteroid 17-beta d↑HSD3B,HSD3B↑HSF1,Heat Shock Factor 1↑HSP27,Heat shock protein 27↑HSP70/HSPA5,heat shock proteins ↑HSP72,Heat Shock Protein 72↑HSP90,HSP90↑HSPs,Heat shock proteins↑hTERT/TERT,human telomerase reve↑hyperG,hyperglycemia↑Hypoxia,Hypoxia↑IAP1,cIAP1, cellular Inhibitor o↑IAP2,cIAP2, cellular Inhibitor o↑ICAD,inhibitor of caspase-activa⇅ICAM-1,Intercellular Adhesion Mo↑ICD,immunogenic cell death (ICD)↓Id1,Inhibitor of DNA binding 1(I↑IDE,Insulin-Degrading Enzyme↓IDH1,isocitrate dehydrogenase 1 ↑IDH2,isocitrate dehydrogenase 2 ↑IDO,indoleamine 2,3-dioxygenase↑IDO1,indoleamine 2, 3-dioxygenas↑IFN-γ,Interferon-γ?IGF-1,insulin-like growth factor↑IGF-1R,insulin-like growth facto↑IGF-2,Insulin-like growth factor↑IGFBP1,Insulin-like Growth Facto↓IGFBP3,Insulin-Like Growth Facto↓IGFBP7,Insulin-like Growth Facto↓IGFR,Insulin-like Growth Factor ↑Igs,immunoglobulins (IgG and IgM⇅Ikaros,Ikaros↓IKKα,IκB kinase alpha)↑IL1,Interleukin-1↑IL10,Interleukin-10↑IL12,Interleukin-12↓IL17,Interleukin-17↑IL18,Interleukin 18↑IL1α,interleukin-1 alpha↑IL1β,interleukin-1 beta↑IL2,Interleukin-2⇅IL22,Interleukin-22↑IL23,Interleukin 23↑IL28,Interleukin-28↑IL33,Interleukin-33↑IL4,interleukin 4↑IL5,Interleukin-5⇅IL6,Interleukin-6↑IL8,Interleukin-8↑IL9,Interleukin-9⇅IM,interstitial markers↑Imm,immunostimulatory↓IMPDH1,inosine monophosphate deh↑IMPDH2,inosine monophosphate deh↑importin α/β,importin α/β (k↑Inf,Infection↑INF-γ,interferon gamma↓Inflam,inflammation↑iNOS,Inducible nitric oxide synt↑INR,International Normalized Rat?Insulin,Insulin↑IP-10/CXCL-10,Interferon-γ(IFN)⇅IR,Insulin Receptor pathway↑IRAK4,interleukin-1 receptor-ass↑IRE1,Inositol-Requiring Enzyme 1↑IRF3,Interferon Regulatory Facto↓Iron,Iron↑IronCh,Iron Chelator?IRP1,Iron regulatory protein 1↑ITGA1,Integrin Subunit Alpha 1↑ITGA11,Integrin α11↑ITGA5,Integrin alpha 5↑ITGB1,Integrin beta-1↑ITGB3,integrin β3↑ITGB4,Integrin Subunit Beta 4↑ITGB6,Integrin Subunit Beta 6↑IκB,IκB kinase(α)↓JAK,Janus kinases↑JAK1,Janus kinase 1↑JAK2,Janus kinase 2↑JAK3,Janus kinase 3↑JAML,Junctional Adhesion Molecul⇅JNK,c-Jun N-terminal kinase (JNK↑Jun,Jun↑JWA,JWA protein or JWA gene↓K17,Keratin 17↑KCNQ1OT1,KCNQ1OT1↑KDM5C,lysine (K)-specific demeth↓KDM6A,lysine (K)-specific demeth↓KDR/FLK-1,Kinase insert Domain-C↑Keap1,Kelch-like ECH-associated ↓KeyT,Keytones∅Ki-67,Ki-67 protein↑KIF2C,Kinesin Family Member 2C↑KISS1,KISS1↓KIT,KIT↑KLF2,Krüppel-like factor 2↓KLF4,Kruppel-like factor 4↓KLF5,Krüppel-like factor 5↑KRAS,v-Ki-ras2 Kirsten rat sarco↑L-sel,L‑selectin/CD62L↓lact/pyru,lactate/pyruvate ratio↑lactateProd,lactate production↑LAMA5,laminin alpha 5↑LAMB3,Laminin subunit beta-3↑LAMP1,Lysosome-Associated Membra↑LAMP2,Lysosome-Associated Membra↑LAMs,Laminins↑LAR,lactate receptor↑LAT,L-Type Amino Acid Transporte↑LATgene,linker for activation of↓LC3‑Ⅱ/LC3‑Ⅰ,ratio of LC3↑LC3A,Microtubule-associated prot↑LC3B,microtubule-associated prot↑LC3B-II,LC3B-II↑LC3I,Lysosomal-associated membra↓LC3II,Microtubule-associated pro↑LC3s,Autophagosome Proteins↑LDH,Lactate Dehydrogenase↑LDHA,Lactate dehydrogenase A↑LDHB,Lactate dehydrogenase B↑LDL,LDL-cholesterol↑LEF1,Lymphoid enhancer-binding f↑Let-7,Let-7↓LGR5,Leucine-rich repeat-contain↑LIF,leukemia inhibitory factor↑lipid-P,lipid peroxidation↑lipidDe,Lipid Deposition↑lipidLev,Lipid Levels↑lipoGen,lipogenesis↑LOX1,Lectin-like oxidized low-de↑LPS,LPS↑LRP1,Low-Density Lipoprotein Rec↓LRP6,Low-density lipoprotein rec↑LymphAG,Lymphangiogenesis↑lysoM,Lysosome Membrane Integritâ†�lysoMP,lysosomal membrane permea↑LysoPr,lysosomal proteolysis↑lysosome,lysosome/lysosomal↑M1,M1 macrophages↓M2 MC,M2 macrophage conversion↑Macrophages,Macrophages⇅MAD,MAD proteins↓Mag,Magnesium↓MALAT1,Metastasis Associated Lun↑MAOA,Monoamine Oxidase A↑MAOB,Monoamine oxidase B↑MAP2K1/MEK1,mitogen-activated pr↑MAP3K1,mitogen-activated protein↓MAPK,mitogen-activated protein k↑MARK4,Microtubule Affinity-Regul↑Maspin,SERPINB5↓Matr,matriptase↑MATs,Methionine Adenosyltransfer↑MBD2,Methyl-CpG binding domain p↑Mcl-1,myeloid cell leukemia 1↑MCM2,Minichromosome Maintenance ↑MCP1,CCL2,monocyte chemotactic p↑MCT1,Multiple Copies in T-cell m↑MCT4,Monocarboxylate Transporter↑MCU,mitochondrial calcium unipor↑MDA,Serum malondialdehyde↑MDM2,Double Minute 2 homolog↑MDMX,MDM4↑MDR1,Multidrug Resistance 1↑MDSCs,Myeloid-derived suppressor↑MeCP2,Methyl-CpG-Binding Protein↑MED12,mediator complex subunit 1↑MEG3,Maternally Expressed Gene 3↓MEK,Mitogen-Activated Protein Ki↑memory,memory?MEN1,multiple endocrine neoplasi↑MET,mesenchymal-epithelial-trans↑Mets,Metallothioneins↓MGMT,O^6^-methylguanine-DNA meth↓MGO,Methylglyoxal↑Mich,Michael addition reaction.∅MIF,Macrophage Migration Inhibit↑MIP-1β,Macrophage Inflammatory ↑MIP‑1α,CCL3?MIP2,Macrophage Inflammatory Pro⇅miR-101,miR-101↓miR-125b,miR-125b↑miR-126,miR-126↓miR-127-5p,miR-127-5p↓MiR-1275,MiR-1275↑miR-129-5p,miR-129-5p↓miR-130a,miR-130a microRNA↑miR-133a-3p,miR-133a-3p↓miR-139-5p,miR-139-5p↓miR-141,miR-141⇅miR-142-3p,miR-142-3p microRNA?miR-143,miR-143↓miR-145,miR-145↓miR-148a,Micro RNA 148a↓miR-15,miR-15↓miR-155,miR-155↑miR-17,miR-17↑miR-192-5p,miR-192-5p↓miR-194,miR-194↓miR-19b,MicroRNA-19↑miR-20,miR-20↑miR-200b,miR-200b↓miR-200c,miR-200c↓miR-203,miR-203?miR-205,microRNA 205⇅miR-206,miR-206↓miR-21,miR-21↑miR-210,miR-210↑miR-215-5p,miR-215-5p↓miR-218,miR-218?miR-22,miR-22↓miR-221,miR-221↑miR-25-5p,miR-25-5p↑miR-27a-3p,miR-27a-3p↑miR-29b,miR-29b↓miR-301a-3p,miR-301a-3p↑miR-30a-5p,miR-30a-5p↓miR-320a,miR-320a↓miR-330-5p,miR-330-5p↓miR-340,miR-340↓miR-34a,mir-34 precursor family↓miR-34b-5p,miR-34b-5p↓miR-384,miR-384↓miR-409-3p,miR-409-3p↓miR-429,miR-429↓miR-448,microRNA 448↓miR-485,miR-485↓miR-486,miR-486↓miR-491,miR-491↓miR-497,miR-497↓miR-548ah-5p,miR-548ah-5p⇅miR-7641,miR-7641⇅miR-99,miR-99↓miRâ€�222,miRâ€�222↑MitoP,Mitophagy?mitResp,mitochondrial respiratio↓MKI67,MKI67 (coding for the prot↑MKK4,Mitogen-Activated Protein K⇅MKP1,MAP kinase phosphatase 1↑MKP2,MAP kinase phosphatase 2↑MKP5,MKP5↓MLH1,mutL homolog 1, colon cance↓MLKL,Mixed Lineage Kinase Domain↓MLL2,myeloid/lymphoid or mixed-l↓MLL3,myeloid/lymphoid or mixed-l↓MLPH,Melanophilin↓MMP,ΔΨm, mitochondrial membran↓MMP-10,Matrix Metalloproteinase-↑MMP1,Matrix metalloproteinases↑MMP1:TIMP1,MMP1:TIMP1 ratio↑MMP11,matrix metalloproteinase 1↑MMP13,MMP13↑MMP14,MMP14↑MMP17,Metalloproteinase 17↑MMP2,metalloproteinase-2↑MMP3,Matrix metalloproteinase-3↑MMP7,metalloproteinase-7↑MMP9,MMP9↑MMP9:TIMP1,MMP-9/TIMP-1 ratio↑MMPs,Matrix metalloproteinases↑MOB1,MOB Kinase Activator 1↑monoA,monoamines?Mood,Behaviour↓Mortalin,mtHsp70↑motorD,motor function?mPGES-1,Microsomal prostaglandin↑MPL,myeloproliferative leukemia ↑MPO,myeloperoxidase (MPO)↑MPOD,Macular Pigment Optical Den↓MPT,mitochondrial permeability t⇅MRGPRF,Mas-related G-protein cou↑MRP,Multidrug Resistance-Associa↑MRP1,Multidrug Resistance Protei↑MSCmark,MSC markers?MSCs,mesenchymal stem cells?MSH2,mutS homolog 2, colon cance↓MSH6,mutS homolog 6 (E. coli)↓MSI,Microsatellite Instability↓Mst1,Mammalian Ste20-like kinase↓mtDam,mitochondrial damage?mTOR,mammalian target of rapamyc↑mTORC1,mammalian target of rapam↑mTORC2,mammalian target of rapam↑MUC1,Mucin 1↑MUC1-C,MUC1-C↑MUC4,mucin, a high-molecular-wei↑Myc,v-myc avian myelocytomatosis↑MyD88,Myeloid differentiation fa↑N-cadherin,N-cadherin↑n-MYC,n-MYC Oncogene↑NA,NA?NAD,Nicotinamide adenine dinucle↓NADH,Nicotinamide Adenine Dinucl↑NADH:NAD,NADH:NAD+ ratio↑NADHdeh,NADH dehydrogenases⇅NADPH,Nicotinamide adenine dinuc↑NADPH/NADP+,NADPH/NADP+ ratio↑NAF1,Neutrophil-activating facto↑NAIP,Neuronal Apoptosis Inhibito⇅Nanog,human hNanog protein coded↑NBR2,long noncoding RNA neighbor↑NCAM,Neural Cell Adhesion Molecu↑NCOA4,Nuclear Receptor Coactivat?NCOR1,nuclear receptor co-repres?NDRG1,N-myc Downstream Regulated↓Necroptosis,Necroptosis⇅necrosis,necrosis?NEDD9,Neural precursor cell expr↑NEP,Neprilysin↓Nestin,Nestin↑Netrins,Netrins↑neuroG,neurogenesis?Neurog1,Neurogenin 1↑neuroP,neuroprotective↓NeuroT,neurotensin↑Neut,neutrophils↑NF-kB,Nuclear factor kappa B↑NF1,neurofibromin 1↓NF2,neurofibromin 2 (merlin)↓NFAM1,Neural Factor Activating M↑NFAT,nuclear factor of activated↑NFE2L2,nuclear factor (erythroid↑NGF,Nerve Growth Factor↓NH3,ammonia↑NHE1,Na+/H+ exchanger isoform 1↑NHE3,Sodium/Hydrogen Exchanger 3⇅NICD,Notch Intracellular Domain↑NK cell,NK cell activity?NKD2,Naked cuticle homolog 2↓NKG2D,natural killer group 2, me⇅NKX3.1,Homeobox protein Nkx-3.1↓NLRP3,NOD-like receptor pyrin do↑NM23,NM23↓NNMT,Nicotinamide N-methyltransf↑NO,Nitric Oxide↑NOS2,nitric oxide synthase 2↑NOTCH,↑NOTCH1,Notch homolog 1, transloc⇅NOTCH2,Notch homolog 2 (Drosophi⇅NOTCH3,Notch homolog 3↑NOX,NADPH oxidase↑NOX4,NADPH oxidase 4↑NOXA,Phorbol-12-myristate-13-ace↓NPC1L1,Niemann–Pick C1-Like 1⇅NPM1,nucleophosmin 1 (nucleolar ↑NPY,Neuropeptide Y⇅NQO1,NAD(P)H quinone dehydrogena↑NQO2,N-ribosyldihydronicotinamid?NRAS,neuroblastoma RAS viral (v-↑Nrf1,Nuclear factor erythroid 2-⇅NRF2,nuclear factor erythroid 2-↑NSE,Neuron-specific enolase↑NTRK,NTRK↑nucleolin,nucleolin↑OAA,oxaloacetate∅OATPs,Organic Anion Transporting⇅OATs,Organic Anion Transporters?Obesity,Obesity↑OCN,Osteocalcin↑OCR,Oxygen consumption rate↓OCT4,Octamer-binding transcripti↑oncosis,Oncosis?OPG,Osteoprotegerin↑OPN,Osteopontin↑OS,overall survival?OSI,oxidative stress index?OSM,oncostatin⇅other,other?OV6,OV6↑OXPHOS,Oxidative phosphorylation↑P-gp,permeability-glycoprotein↑p16,protein 16↓p19,p19/CDKN2D↓P21,P21↓p27,p27kip1↓P2X7,purinoceptor 7↑p300,p300↑p38,p38↑p42,p42 MAPK↑p44,p44/ERK1↑P450,cytochrome P450 (CYP) famil↑p50,p50↑P53,P53-Guardian of the Genome↑p53 Wildtype,p53 Wildtype↓p62,p62/sequestosome 1 (SQSTM1)↑p65,RelA↑p66Shc,p66Shc⇅p70S6,phospho-S6↑P70S6K,p70 S6 kinase↑p73,p73↓p85S6K,isoform of S6 kinase↑P90RSK,90 kDa Ribosomal S6 Kinas↑Pain,Pain?PAK,p21-activated kinases↑PAK1,↑PAO,PAO gene↑PAR-2,Protease-activated recepto↑Paraptosis,Paraptosis↓PARK2,PARKIN↓PARP,poly ADP-ribose polymerase ↑PARP1,Poly [ADP-ribose] polymera↑PARP16,ARTD15↑pax,paxillin↑PAX5,paired box 5↓PBRM1,polybromo 1↓PCAF,p300/CBP-associated factor↑PCBP1,Poly(rC) Binding Protein 1↑PCK1,phosphoenolpyruvate carboxy⇅PCLAF,Proliferating Cell Nuclear↑PCNA,Proliferating Cell Nuclear ↑PD-1,Programmed Death-1↑PD-L1,Programmed Death-Ligand 1↑PD-L2,Programmed Death-Ligand 2↑PDCD4,PDCD4 Programmed Cell Deat↓PDE4,Phosphodiesterase 4↑PDGF,Platelet-derived growth fac↑PDGFR-BB,Platelet-Derived Growth↑PDGFRA,platelet-derived growth f↑PDH,mitochondrial pyruvate dehyd↓PDHA1,Pyruvate Dehydrogenase E1 ↓PDHB,pyruvate dehydrogenase E1 b↓PDI,Protein Disulfide Isomerase↑PDK1,Pyruvate dehydrogenase kina↑PDK3,Pyruvate Dehydrogenase Kina↑PDKs,pyruvate dehydrogenase kina↑PDT+,PDT+cells↑Perforin,Perforin⇅PERK,protein kinase-like ER kina↑PFK,Phosphofructokinase↑PFK1,Phosphofructokinase-1↑PFK2,PFK2↑PFKFB2,6-Phosphofructo-2-Kinase/↑PFKL,Phosphofructokinase, Liver↑PFKM,Phosphofructokinase, Muscle↑PFKP,Phosphofructokinase, Platel↑PGAM1,Phosphoglycerate mutase 1↑PGC-1α,Peroxisome proliferator-↑PGC1A,PPARγ Coactivator 1-alpha↑PGD2,prostaglandin D2⇅PGE1,Prostaglandin E1?PGE2,Prostaglandin E2↑PGK1,Phosphoglycerate kinase 1↑PGM1,Phosphoglucomutase 1↑pH,↓PHDs,Prolyl Hydroxylases↓PHF6,PHD finger protein 6↓PhotoS,PhotoSensitzer?PI3K,Phosphatidylinositide-3-Kin↑PI3K/Akt,PI3K/Akt signaling↑PI3k/Akt/mTOR,Phosphoinositide 3↑PI3K/mTOR/ETS2,PI3K/mTOR/ETS2 pa↑PIAS-3,Protein Inhibitor of Acti↓Piezo1,Piezo1↑PIK3CA,phosphoinositide-3-kinase↑PIK3R1,PIK3R1/p85S6 Phosphatidyl↑Pin1,Peptidyl-prolyl cis-trans i↑PINK1,PTEN-induced kinase 1↓PIP3,Phosphatidylinositol (3,4,5↑PIR,Phosphoinositide-interacting↑Pirin,Pirin↑PKA,protein kinase A↑PKCδ,Protein Kinase C delta⇅PKL,liver isoform of pyruvate ki?PKM1,pyruvate kinase muscle isof?PKM2,Pyruvate Kinase, Muscle 2↑PKM2:PKM1,PKM2/PKM1 ratio↑PLC,perlecan?PleEff,pleural effusion↑PLEKHM3,PLEKHM3↑PLIN1,Perilipin 1?POLD1,POLD1↑polyA,polyamine↑PONs,paraoxonase↑Poor perfusion,Poor perfusion?PP2A,serine/threonine phosphatas↓PPARα,Peroxisome Proliferator-A⇅PPARγ,Peroxisome proliferator-a↑PPP,pentose phosphate pathway↑PPP2R1A,protein phosphatase 2 (f↓PR,Progesterone receptor↓PRAS40,proline-rich Akt substrat↑pRB,retinoblastoma protein↓PRC2,Polycomb repressive complex↑PRDM1,PR domain containing 1, wi↓PRKCG,Protein Kinase C Gamma↑PRNP,Prion Protein (PRioN Protei↑proApCas,proapoptotic cascade↓PRODH,proline dehydrogenase↓proline,proline↑Prot,Protein Levels?Proteasome,Proteasome↑Prx,Peroxiredoxin↑Prx3,peroxiredoxin-3↑Prx4,Peroxiredoxin 4↑Prx6,Peroxiredoxin 6⇅PrxI,Peroxiredoxin I↑PrxII,Peroxiredoxin II↑pS2/TFF1,pS2/TFF1↓PSA,prostate-specific antigen↑PSD95,Postsynaptic density prote↓PSMB5,proteasome subunit beta ty↑PTCH1,12-transmembrane cell surf↓PTCH2,PTCH2↓PTEN,phosphatase and tensin homo↓PTP1B,protein tyrosine phosphata↑PTPN11,protein tyrosine phosphat↑PTPN6,SHP1/Protein Tyrosine Phos↓PUMA,p53 upregulated modulator o↓PYCR1,Pyrroline-5-Carboxylate Re↑Pyro,Pyroptosis?Pyruv,Pyruvate↑QoL,Quality of Life↓R5P,ribose-5-phosphate↑RAAS,Renin-Angiotensin-Aldostero?Rac1,Ras-related C3 botulinum to↑RAD51,RAD51?radioP,RadioProtective↓RadioS,RadioSensitizer↓Raf,RAF kinases↑RAGE,Receptor for advanced glyca↑RANKL,Receptor Activator of Nucl↑RANTES,CCL5↑RARα,RARα (NR1B1)↑RARβ,RARβ (NR1B2)↓RARγ,RARγ (NR1B3)↑RAS,RAS↑RB1,retinoblastoma 1 gene↓RBM3,RNA-binding motif protein 3↑RECK,Reversion Inducing Cysteine↓REL,V-rel avian reticuloendothel↑Remission,Remission?RenoP,K,Renoprotection↓RET,Rearranged during Transfecti?RHBDD1,Rhomboid Domain Containin↑Rho,Rho GTPases?RIP1,Receptor-Interacting Protei↑RIP3,Receptorâ€�Interacting Prot↓Risk,Risk/Opp. Chemopreventive?RKIP,Raf Kinase Inhibitor Protei↓RNF43,ring finger protein 43?RNR,Ribonucleotide Reductase↑RNS,reactive nitrogen species?ROCK1,Rho-associated coiled-coil↑ROMO1,Reactive Oxygen Species Mo?ROS,Reactive Oxygen Species?RPM,radical pair mechanism?RPS6KA1,ribosomal protein S6 kin↑RPSA,Ribosomal Protein SA↑RSK,Ribosomal S6 Kinase↑RTK-RAS,RTK-RAS↑RUNX1,runt-related transcription?RUNX2,Runt-related transcription↑S6,ribosomal protein S6↑S6K,S6 kinase↑SA,Sialic acid↑SA of VW,Structural abnormalitie?SAL,specific acetylation level?SAM-e,S-adenosylmethionine⇅SAPK,stress-activated protein ki?SAT1,Spermidine/Spermine N1-Acet↑SCD1,Stearoyl-CoA Desaturase 1↑SCF,Stem Cell Factor?SD,Stable Disease?SDC1,Syndecan-1 (SDC-1)↓SDH,Succinate dehydrogenase/Comp?SE-cad,Selenocysteine-containing?Securin,PTTG1↑selectivity,selectivity∅selenoP,selenoproteins⇅selm,selenium↓Sema3A/PlexinA1,Sema3A/PlexinA1⇅Sepsis,Sepsis↑serineP,serine protease↑SESN2,Sestrin 2↓Set9,SETD7 (SET domain containin⇅SETBP1,SET binding protein 1?SETD2,SET domain containing 2?SF3B1,splicing factor 3b, subuni?sFasL,soluble Fas Ligand↑SFRP5,Secreted Frizzled-Related ↓SGLTs,Sodium-Glucose Cotransport↑SHARP,SHARP1/BHLHE41⇅Sharpin,SHANK-associated RH doma↑SHBG,Sex Hormone-Binding Globuli↑Shc,Shc signaling proteins?Shh,sonic hedgehog↑SHP1,Src Homology region 2 domai↓SIRT1,Sirtuin 1 protein?SIRT2,Sirtuin 2↓SIRT3,Sirtuin 3↓SIRT6,Sirtuin 6↓SK,Sphingosine kinases↑SLC12A5,SLC12A5↑SLC25A1,CIC↑Sleep,Sleep Quality?Slug,transcription factor Slug↑Smad1,Smad1⇅SMAD2,SMAD family member 2?SMAD3,SMAD3↑SMAD4,SMAD family member 4↓SMAD5,SMAD5⇅Smad7,Smad7?SMARCA4,SWI/SNF related, matrix ↓SMARCB1,SWI/SNF related, matrix ↓SMCT1,SLC5A8↓SMG1,Suppressor of Morphogenetic↓Smo,G-protein-coupled receptor-l↑Snail,Snail↑SNCG,SNCG gene↑SOCS-3,Suppressor of Cytokine Si↓SOCS1,suppressor of cytokine sig↓SOD,superoxide dismutase↑SOD1,superoxide dismutase 1⇅SOD2,MnSOD⇅sonoP,sonoporation↓sonoS,sonosensitizer∅SOX2,SOX2↑SOX4,SRYâ€�box transcription fac↑SOX9,SRY (sex determining region↑Sp1/3/4,Specificity Protein↑SPARC,secreted protein acidic an⇅SPOP,speckle-type POZ protein?SPP1,Secreted phosphoprotein 1?Src,Src kinase↑SRD5A1,SRD5A1↑SREBF2,Sterol Regulatory Element↑SREBP1,sterol regulatory element↑SREBP2,Sterol Regulatory Element↑SRSF2,SRSF2 serine/arginine-rich?SSAT,Spermidine/Spermine N1-Acet?SSBP1,single-stranded DNA bindin⇅STAC2,SH3 and cysteine-rich doma↑STAG2,stromal antigen 2↓StAR,Steroidogenic Acute Regulat↑STAT,Signal transducer and activ↑STAT1,Signal transducer and acti↓STAT2,Signal Transducer and Acti↓STAT3,Signal transducer and acti↑STAT4,Signal transducer and acti↓STAT5,Signal transducer and acti↑STAT6,Signal Transducer and Acti↑STEAP3,Six Transmembrane Epithel↑STEP,STriatal-Enriched protein t↑STK11,serine/threonine kinase 11↓Strength,physical strength?Sufu,Sufu gene↓survivin,BIRC5↑SUZ12,Suppressor of zeste 12↑SVCT-2,Sodium-dependent Vitamin ↑SXR,PXR-Steroid and Xenobiotic R↑Symptoms,Symptoms?T-cadherin,T-cadherin/CDH13↑T-Cell,T lymphocytes↓T-SOD,tissue superoxide dismutas⇅TAC,total antioxidant capacity↓talin,talin↑TAMS,tumor-associated macrophage↑TANs,tumor-associated neutrophil↑TAp63α,TAp63α↓TarDef DNArep,Target deficient D?TAS,Tumor Angiogenesis Score↑TASc,Tumor Angiogenesis Score↑tau,tau?TAZ,Transcriptional Coactivator ↑TBARS,Thiobarbituric Acid Reacti↑TBX15,T-box transcription factor?TCA,Tricarboxylic Acid Cycle⇅TCF,T-cell factor (Tcf) family↑TCF-4,Transcription Factor 4⇅Telomerase,Telomerase↑testos,testosterone↑TET1,Ten-Eleven Translocation 1↓TET2,tet oncogene family member ↓TET3,Ten-Eleven Translocation me⇅Tf,Transferrin↑TFAP2A,Transcription Factor AP-2⇅TFEB,Transcription Factor EB↑TfR1/CD71,Transferrin receptor p↑TGF-β,transforming growth facto↑TGF-β1,Transforming Growth Fact↑TGFβR1,transforming growth fact↑Th1 response,T helper response↓Th17,T helper 17 (Th17) cells⇅Th2,Type 2 helper cell↑THBS2,thrombospondin 2 gene↑Thiols,Thiols↑TILs,tumor-infiltrating lymphocy↓TIM-3,T-cell immunoglobulin and ↑TIMP1,Tissue Inhibitor of Metall↑TIMP2,Tissue Inhibitor of Metall⇅TIMP3,tissue inhibitor of metall?TJ,Tight junctions⇅TKT,transketolase↑TLE1,Transducin-Like Enhancer of↑TLR1,Toll-Like Receptor 1⇅TLR2,Toll-Like Receptor 2⇅TLR4,Toll-like receptor 4?TLS,Tumor lysis syndrome?TNC,tenascin-C↑TNF-α,TNF-α↑TNF-β,Tumor Necrosis Factor-bet↑TNFAIP3,tumor necrosis factor, a↓TNFR 1,Tumor necrosis factor rec⇅TOP1,Topoisomerase I↑TOP2,Topoisomerase II↑TOPflash,TOPflash∅TOS,total oxidant status↑toxicity,toxicity?TP53,tumor protein p53↓TPI,Triosephosphate Isomerase↑TPM4,Tropomyosin 4↑TRAF7,TNF receptor-associated fa⇅TRAIL,tumor necrosis factor-relaâ†�TRAILR,tumor necrosis factor-relâ†�Trans Reg,Transcriptional regulaâ†�Treg lymp,Treg lymphocytes↑TregCell,Treg cells↑TREM-1,triggering receptor expre↑TRIB3,tribbles homolog 3↑TRIF,Toll/IL-1 receptor domain-c⇅TrkB,Tropomyosin receptor kinase↑Trop2,Trop2↑TRPC1,Transient Receptor Potenti↑TRPM7,transient receptor potenti↑TRPV1,transient receptor potenti⇅Trx,Thioredoxin↑Trx1,Thioredoxin 1↑Trx2,thioredoxin 2↑TrxR,Thioredoxin Reductase↑TrxR1,thioredoxin reductase 1↑TrxR2,thioredoxin reductase-mito↑trypsin,trypsin↑TS,thymidylate synthase↑TSC1,tuberous sclerosis 1↓TSC2,tuberous sclerosis complex ↓TSHR,thyroid stimulating hormone↓TSP-1,Thrombospondin-1↓TumAuto,Tumor autophagy↓TumCA,Tumor Cell adhesion↑TumCCA,Tumor cell cycle arrest↓TumCD,Tumor Cell Death↓TumCG,Tumor cell growth↑TumCI,Tumor Cell invasion↑TumCM/A,Tumor cell metabolism/ac↑TumCMig,Tumor cell migration↑TumCP,Tumor Cell proliferation↑tumCV,Cell Viability↑TumMeta,Cancer Metastasis↑TumN,Tumor necrosis↓TumPF,Tumor-promoting fibroblast↑TumPInf,Tumor-promoting inflamma↑TumVol,Tumor Volume↑TumW,Tumor Weight↑TUNEL,Terminal deoxynucleotidyl ⇅Twist,Twist↑TXA2,thromboxane A2↑TXNIP,TBP-2↓Tyro3,Tyro3↑tyrosinase,tyrosinase↑U2AF1,U2 small nuclear RNA auxil↑UBE2C,Ubiquitin-conjugating enzy↑UCP1,mitochondrial uncoupling pr↑UCPs,uncoupling proteins?UHRF1,Ubiquitin-like with PHD an↑uPA,Urokinase plasminogen activa↑uPAR,Urokinase-type plasminogen ↑UPR,Unfolded Protein Response↑uricA,uric acid↑UrinaryC,urinary continence↓UroPA,Urokinase plasminogen acti↑USF1,Upstream transcription fact↑VCAM-1,Vascular cell adhesion pr↑VDAC1,Voltage-Dependent Anion Ch?VDR,Vitamin D receptor↓VEGF,Vascular endothelial growth↑VEGFR2,Vascular Endothelial Grow↑VGCC,Voltage-gated calcium chann↑VHL,von Hippel-Lindau tumor supp↓Vim,Vimentin↑vinculin,vinculin⇅VitC,Vitamin C levels?VitD,Vitamin D↓VitE,Vitamin E (trolox)?VM,vasculogenic mimicry↑Warburg,Warburg Effect↑Weight,Weight↓Wmax,Wmax↓Wnt,Wingless-related integration↑Wnt/(β-catenin),Wnt/(β-catenin↑Wound Healing,Wound Healing?WT1,Wilms tumor 1↑XBP-1,X-box binding protein 1↑xCT,SLC7A11↑XIAP,X-linked inhibitor of apopt↑XIST,X-inactive specific transcr↓XO,xanthine oxidase↑YAP/TEAD,YAP/TEAD activity↑YMcells,YOUNG’S MODULUS cancer↓ZBTB10,ZBTB transcription Factor↓Zeb1,Zinc finger E-box-binding h↑ZEB2,Zinc Finger E-Box Binding H↑ZFX,Zinc Finger X-linked↑ZO-1,Zonula occludens-1↓α-SMA,α-smooth muscle actin↑α-tubulin,α-tubulin↑β-Amyloid,β-Amyloid Fibrils↑β-catenin/ZEB1,β-catenin/ZEB1↑β-Endo,β-Endorphin↓β-oxidation,Beta Oxidation?β-TRCP,beta-transducin repeat-c↑γH2AX,gamma-H2AX↑γδ T-cell activity,γδ T-cell↓NA	,NAp‑,cl‑pro,pe-,excircâproâ€ac‑i-,inm-,momt-,mpol-,ox-,ord-,rc-,ce	?↓↑⇅â†�?∅

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