OR13G1 Cancer Research Results

OR13G1, OR1-37, Olfactory Receptor Family 13 Subfamily G Member 1: Click to Expand ⟱
Source:
Type:

OR13G1 (Olfactory Receptor Family 13 Subfamily G Member 1) — Seven-transmembrane G-protein-coupled olfactory receptor involved in odorant recognition and G-protein-mediated signal transduction. Olfactory receptors can also be ectopically expressed in non-olfactory tissues, including some cancers.

Typical modulation in cancer: Insufficient evidence for a universal direction. Ectopic olfactory-receptor expression can influence proliferation, migration, intracellular Ca2+, cAMP, and other signaling pathways, but OR13G1-specific cancer evidence is limited.

Typical mechanistic relationship: Ligand binding → OR13G1 activation → heterotrimeric G-protein signaling → downstream second-messenger pathways.
Scientific Papers found: Click to Expand⟱
9044- PatchO,    Patchouli oil and its main component patchouli alcohol inhibit colorectal cancer by activating ectopic olfactory receptor
- vitro+vivo, CRC, HCT116
OS↑, TumCG↓, Inflam↓, AMPK↑, Ferroptosis↑, OR13G1?, CaMKII ?, TumPF↓, TumCMig↓, Tumccf↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 1,  

Cell Death(tgid=5) ⓘ

Ferroptosis↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

CaMKII ?, 1,   OR13G1?, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

TumCG↓, 1,  

Migration(tgid=13) ⓘ

TumCMig↓, 1,   TumPF↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Inflam↓, 1,  

Clinical Biomarkers(tgid=22) ⓘ

Tumccf↓, 1,  

Functional Outcomes(tgid=23) ⓘ

OS↑, 1,  
Total Targets: 10

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: OR13G1, OR1-37, Olfactory Receptor Family 13 Subfamily G Member 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:1915  State#:%  Dir#:0
  wNotes=0  sortOrder:rid,rpid

 

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