Th17 Cancer Research Results

Th17, T helper 17 (Th17) cells: Click to Expand ⟱

Source:

Type:

Th17 cells are a distinct subset of CD4+ T helper cells characterized by their production of interleukin-17 (IL-17) family cytokines (most notably IL-17A and IL-17F), as well as other effector molecules like IL-21 and IL-22. These cells play a key role in mediating inflammatory responses and defending against extracellular pathogens, particularly fungi and bacteria.

Th17 cells have been reported to exhibit both pro-tumor and anti-tumor properties:
– Anti-Tumor Effects: In some contexts, the pro-inflammatory cytokines produced by Th17 cells can enhance anti-tumor immunity by recruiting and activating other immune cells (e.g., cytotoxic T lymphocytes and natural killer cells).
– Pro-Tumor Effects: Conversely, chronic inflammation driven by Th17 cells may promote tumor progression by encouraging angiogenesis, suppressing effective anti-tumor immune responses, or by directly supporting tumor cell survival and metastasis.

Scientific Papers found: Click to Expand⟱

1197-

MAG,

Magnolol as STAT3 inhibitor for treating multiple sclerosis by restricting Th17 cells

in-vivo,

MS,

mice

Weight↑, Th17↓, STAT3↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

STAT3↓, 1,

Immune & Inflammatory Signaling(tgid=16) ⓘ

Th17↓, 1,

Functional Outcomes(tgid=23) ⓘ

Weight↑, 1,
Total Targets: 3

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: Th17, T helper 17 (Th17) cells

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells