Urea Cancer Research Results

Urea, Urea: Click to Expand ⟱
Source:
Type: Biomarker

Urea is the principal nitrogenous waste product formed in the liver through the urea cycle from ammonia generated during amino-acid metabolism. It is transported in blood and excreted mainly by the kidneys. Urea is a metabolite and clinical biomarker, not a molecular signalling target. Its direction is context-dependent: increased serum urea may indicate renal impairment, dehydration, protein catabolism, or treatment toxicity, while reduced urea may reflect impaired hepatic synthesis, malnutrition, or altered nitrogen metabolism. Reference.



Scientific Papers found: Click to Expand⟱
8453- OM,    Origanum majorana Attenuates Nephrotoxicity of Cisplatin Anticancer Drug through Ameliorating Oxidative Stress
- in-vivo, Nor, NA
Dose↝, creat↓, Urea↓, uricA↓, BUN↓, MDA↓, GSH↑, SOD↑, Catalase↑, RenoP↑, *ROS↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

Catalase↑, 1,   GSH↑, 1,   MDA↓, 1,   SOD↑, 1,   uricA↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

BUN↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

creat↓, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

RenoP↑, 1,  
Total Targets: 10

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

ROS↓, 1,  
Total Targets: 1

Scientific Paper Hit Count for: Urea, Urea
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:1535  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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