DYRK1B Cancer Research Results

DYRK1B, MIRK,Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1B: Click to Expand ⟱
Source:
Type:
Scientific Papers found: Click to Expand⟱
8648- MBZ,    Mebendazole as a Candidate for Drug Repurposing in Oncology: An Extensive Review of Current Literature
- Review, Var, NA
angioG↓, MMPs↓, MDR1↓, TubPol↓, RadioS?, ChemoSen?, TumCG↓, TumMeta?, OS↑, BioAv↓, BioAv↑, BBB↑, mitA↑, HH↓, Shh↓, Synergy↑, Gli1↓, PTCH2↓, XIAP↓, cl‑PARP↑, Casp3↑, BRAF↓, MEK↓, SYN1↑, Cyt‑c↑, TumVol↓, VEGFR2/KDR/Flk1↓, VEGF↓, VCAM-1↓, DYRK1B↓, QoL↑, Dose↝,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Cell Death(tgid=5) ⓘ

Casp3↑, 1,   Cyt‑c↑, 1,   XIAP↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

BRAF↓, 1,   DYRK1B↓, 1,   MEK↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

cl‑PARP↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

mitA↑, 1,   TubPol↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Gli1↓, 1,   HH↓, 1,   PTCH2↓, 1,   Shh↓, 1,   TumCG↓, 1,  

Migration(tgid=13) ⓘ

MMPs↓, 1,   TumMeta?, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   VCAM-1↓, 1,   VEGF↓, 1,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

SYN1↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 1,   ChemoSen?, 1,   Dose↝, 1,   MDR1↓, 1,   RadioS?, 1,   Synergy↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

BRAF↓, 1,  

Functional Outcomes(tgid=23) ⓘ

OS↑, 1,   QoL↑, 1,   TumVol↓, 1,  
Total Targets: 33

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: DYRK1B, MIRK,Dual Specificity Tyrosine Phosphorylation Regulated Kinase 1B
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:1881  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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