MTA2 Cancer Research Results

MTA2, PID, Metastasis Associated 1 Family Member 2: Click to Expand ⟱
Source:
Type:
Scientific Papers found: Click to Expand⟱
8845- DIM,  I3C,    3,3′-Diindolylmethane and indole-3-carbinol: potential therapeutic molecules for cancer chemoprevention and treatment via regulating cellular signaling pathways
- Review, Var, NA
*BioAv↝, *BioAv↓, *BioAv↓, *AntiAg↑, *ROS↓, *AntiThr↑, *Stroke↓, *CYP1A1↑, *CYP1A2↑, *GSTs↑, *NQO1↑, AntiTum↑, AntiCan↑, TumAuto↓, Let-7↑, miR-34a↑, TumCMig↓, Apoptosis↑, MMP↓, mtDam↑, ROS↑, TumCCA↑, other↝, PSA↓, Dose↝, MMP2↓, MMP3↓, MMP9↓, EGFR↓, RAS↓, PI3K↓, Akt↓, mTOR↓, CDK4↓, cycD1/CCND1↓, P21↑, MDM2↓, TumCP↓, NF-kB↓, RANKL↓, PUMA↓, Wnt↓, MTA2↓, EZH2↓, AhR↓, PTEN↑, NOTCH1↓, IRAK1↓, p27/CDKN1B↓, CDKN1C/p57↓, CDC25↓, EGFR↓, Zeb1↓, FOXM1↓, SOX4↓, E-cadherin↑, uPA↓, uPAR↓,
8851- DIM,    3,3’-Diindolylmethane and its derivatives: nature-inspired strategies tackling drug resistant tumors by regulation of signal transduction, transcription factors and microRNAs
- Review, Var, NA
Apoptosis↑, NF-kB↓, Akt↓, Wnt↓, PI3K↓, mTOR↓, PSA↓, Let-7↓, miR-34a↓, EZH2↓, NOTCH1↓, AR↓, E-cadherin↑, Zeb1↓, Vim↓, Slug↓, EMT↓, MTA2↓, NF-kB↓, IRAK1↓, EGFR↓, SOX4↓, FOXM1↓, p27/CDKN1B↓, AhR↓, EZH2↓, Wnt↓, PUMA↓, AEG1↑, ROS↑, PPARα↑, CycB/CCNB1↑,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

ROS↑, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

CDC25↓, 1,   mtDam↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 2,   MDM2↓, 1,   PUMA↓, 2,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 2,   EGFR↓, 3,   mTOR↓, 2,   PI3K↓, 2,   PTEN↑, 1,   RAS↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

EZH2↓, 3,   FOXM1↓, 2,   miR-34a↓, 1,   miR-34a↑, 1,   MTA2↓, 2,   other↝, 1,   SOX4↓, 2,  

Autophagy & Lysosomes(tgid=9) ⓘ

TumAuto↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK4↓, 1,   CDKN1C/p57↓, 1,   CycB/CCNB1↑, 1,   cycD1/CCND1↓, 1,   P21↑, 1,   p27/CDKN1B↓, 2,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Let-7↓, 1,   Let-7↑, 1,   NOTCH1↓, 2,   TumCP↓, 1,   Wnt↓, 3,  

Migration(tgid=13) ⓘ

AEG1↑, 1,   E-cadherin↑, 2,   EMT↓, 1,   MMP2↓, 1,   MMP3↓, 1,   MMP9↓, 1,   Slug↓, 1,   TumCMig↓, 1,   uPA↓, 1,   uPAR↓, 1,   Vim↓, 1,   Zeb1↓, 2,  

Barriers & Transport(tgid=15) ⓘ

MMP↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

IRAK1↓, 2,   NF-kB↓, 3,   PSA↓, 2,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AhR↓, 1,   AhR↓, 1,   AR↓, 1,   PPARα↑, 1,   RANKL↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 1,   EGFR↓, 3,   EZH2↓, 3,   FOXM1↓, 2,   PSA↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiTum↑, 1,  
Total Targets: 61

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

GSTs↑, 1,   NQO1↑, 1,   ROS↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2,   BioAv↝, 1,   CYP1A1↑, 1,   CYP1A2↑, 1,  

Functional Outcomes(tgid=23) ⓘ

Stroke↓, 1,  
Total Targets: 10

Scientific Paper Hit Count for: MTA2, PID, Metastasis Associated 1 Family Member 2
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:1895  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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