NF-kB Cancer Research Results

NF-kB, Nuclear factor kappa B: Click to Expand ⟱
Source: HalifaxProj(inhibit)
Type:
NF-kB signaling
Nuclear factor kappa B (NF-κB) is a transcription factor that plays a crucial role in regulating immune response, inflammation, cell proliferation, and survival.
NF-κB is often found to be constitutively active in many types of cancer cells. This persistent activation can promote tumorigenesis by enhancing cell survival, proliferation, and metastasis.
Scientific Papers found: Click to Expand⟱
2434- 2DG,    Inhibition of Key Glycolytic Enzyme Hexokinase 2 Ameliorates Psoriasiform Inflammation in vitro and in vivo
- in-vitro, PSA, NA - in-vivo, PSA, NA
HK2↓, NF-kB↓, NLRP3↓,
5463- AF,    Will Auranofin Become a Golden New Treatment Against COVID-19?
- Review, Covid, NA
IL6↓, NF-kB↓, ATF2↓, TrxR↓, ROS↑, Apoptosis↑, IL6↓, Dose↑,
5470- AF,    Exploring a Therapeutic Gold Mine: The Antifungal Potential of the Gold-Based Antirheumatic Drug Auranofin
- Review, Var, NA
TrxR↓, other↝, IL6↑, IL8↑, NK cell⇅, COX2/PTGS2↓, NOS2↓, NRF2↑, Prx↑, Half-Life↑, Dose↝, ROS↑, NF-kB↓,
5468- AF,    The gold complex auranofin: new perspectives for cancer therapy
- Review, Var, NA
TrxR↓, ROS↑, eff↑, Apoptosis↑, TumCG↓, TumCP↓, Akt↓, NF-kB↓, DNAdam↑, eff↝, eff↓, PI3K↓, Akt↓, mTOR↓, Hif1a↓, VEGF↓, Casp3↑, CSCs↓, ATP↓, Glycolysis↓, eff↑, eff↑, MMP↓, AIF↑, toxicity↓,
1334- AG,    Astragalus membranaceus: A Review of Its Antitumor Effects on Non-Small Cell Lung Cancer
- Review, NA, NA
TumCP↓, Apoptosis↑, NF-kB↓, p50↓, cycD1/CCND1↓, Bcl-xL↓, ChemoSen↑, angioG↓, ChemoSen↑,
5444- AG,    A Systematic Review of Phytochemistry, Pharmacology and Pharmacokinetics on Astragali Radix: Implications for Astragali Radix as a Personalized Medicine
- Review, Var, NA
*Imm↑, *antiOx↑, *Inflam↓, AntiTum↑, eff↑, chemoP↑, Dose↝, TumCMig↓, TumCP↓, Akt↓, GSK‐3β↓, MMP2↓, MMP9↓, EMT↓, PI3K↓, Akt↓, NF-kB↓, Inflam↓, TGF-β1↓, TNF-α↓, IL6↓, Fas↓, FasL↓, NOTCH1↓, JNK↓, TumCG↓,
5431- AG,    Advances in research on the anti-tumor mechanism of Astragalus polysaccharides
- Review, Var, NA
AntiTum↑, TumCG↓, TumCI↓, Apoptosis↑, Imm↑, Bcl-2↓, BAX↑, Wnt↓, β-catenin/ZEB1↓, TumCG↓, miR-133a-3p↑, JNK↓, Fas↑, P53↑, P21↑, NOTCH1↓, NOTCH3↓, TumCP↓, TumCCA↑, GPx4↓, xCT/SLC7A11↓, AMPK↑, Beclin-1/ATG6↑, NF-kB↓, EMT↓, Vim↓, TumMeta↓, VEGF↓, EGFR↓, eff↑, eff↑, MMP↓, P-gp/ABCB1↓, MMP9↓, ChemoSen↑, SIRT1↓, SREBP1/SREBF1↓, TumAuto↑, PI3K↓, mTOR↓, Casp3↑, Casp9↑, CD133↓, CD44↓, CSCs↓, QoL↑,
1594- AgNPs,  Citrate,    Silver Citrate Nanoparticles Inhibit PMA-Induced TNFα Expression via Deactivation of NF-κB Activity in Human Cancer Cell-Lines, MCF-7
- in-vitro, BC, MCF7
TNF-α↓, NF-kB↓, antiOx↑, TumCP↓,
334- AgNPs,    Silver-Based Nanoparticles Induce Apoptosis in Human Colon Cancer Cells Mediated Through P53
- in-vitro, Colon, HCT116
Bax:Bcl2↑, P53↑, P21↑, Casp3↑, Casp8↑, Casp9↑, Akt↓, NF-kB↓, DNAdam↑, TumCCA↑,
400- AgNPs,  MF,    Polyvinyl Alcohol Capped Silver Nanostructures for Fortified Apoptotic Potential Against Human Laryngeal Carcinoma Cells Hep-2 Using Extremely-Low Frequency Electromagnetic Field
- in-vitro, Laryn, HEp2
TumCP↓, Casp3↑, P53↑, Beclin-1/ATG6↑, TumAuto↑, GSR↑, ROS↑, MDA↑, ROS↑, SIRT1↑, Ca+2↑, Endon↑, DNAdam↑, Apoptosis↑, NF-kB↓,
389- AgNPs,  Citrate,    Silver Citrate Nanoparticles Inhibit PMA-Induced TNFα Expression via Deactivation of NF-κB Activity in Human Cancer Cell-Lines, MCF-7
- in-vitro, BC, MCF7
TNF-α↓, NF-kB↓,
379- AgNPs,    Effects of green-synthesized silver nanoparticles on lung cancer cells in vitro and grown as xenograft tumors in vivo
- in-vivo, Lung, H1299
NF-kB↓, Bcl-2↓, Casp3↑, survivin↑, TumCG↓,
5356- AL,    Therapeutic role of allicin in gastrointestinal cancers: mechanisms and safety aspects
- Review, GC, NA
Apoptosis↑, TumCP↓, MAPK↓, PI3K↓, Akt↓, NF-kB↓, AntiCan↑, ChemoSen↑, TumCCA↑, Apoptosis↑, BioAv↑, selectivity↑, TGF-β↓, ROS↑, DNAdam↑, p‑P53↑, P21↑, cycD1/CCND1↓, cycE/CCNE↓, CDK4↓, CDK6↓, MMP↓, NF-kB↑, BAX↑, Bcl-2↓, ER Stress↑, Casp↑, AIF↑, Fas↑, Casp8↑, Cyt‑c↑, cl‑PARP↑, Ca+2↑, *NRF2↑, *chemoP↑, *GutMicro↑, CycB/CCNB1↑, H2S↑, HIF-1↓, RadioS↑,
253- AL,    Allicin inhibits invasion and migration of breast cancer cells through the suppression of VCAM-1: Regulation of association between p65 and ER-α
- in-vitro, BC, MDA-MB-231
TumCMig↓, ERK↓, VCAM-1↓, NF-kB↓,
2668- AL,  Rad,    Allicin enhances the radiosensitivity of colorectal cancer cells via inhibition of NF-κB signaling pathway
- in-vitro, CRC, HCT116
RadioS↑, NF-kB↓,
3547- ALA,    Potential Therapeutic Effects of Lipoic Acid on Memory Deficits Related to Aging and Neurodegeneration
- Review, AD, NA - Review, Park, NA
*memory↑, *neuroP↑, *motorD↑, *VitC↑, *VitE↑, *GSH↑, *SOD↑, *Catalase↑, *GPx↑, *5HT↑, *lipid-P↓, *IronCh↑, *AChE↓, *Inflam↓, *GlucoseCon↑, *GLUT3↑, *GLUT4↑, NF-kB↓, *IGF-1↑, *IL1β↓, *TNF-α↓, *cognitive↑, *ChAT↑, *HO-1↑, *NQO1↑,
278- ALA,    The Multifaceted Role of Alpha-Lipoic Acid in Cancer Prevention, Occurrence, and Treatment
- Review, NA, NA
ROS↑, NRF2↑, Inflam↓, frataxin↑, *BioAv↓, ChemoSen↑, Hif1a↓, eff↑, FAK↓, ITGB1↓, MMP2↓, MMP9↓, EMT↓, Snail↓, Vim↓, Zeb1↓, P53↑, MGMT↓, Mcl-1↓, Bcl-xL↓, Bcl-2↓, survivin↓, Casp3↑, Casp9↑, BAX↑, p‑Akt↓, GSK‐3β↓, *antiOx↑, *ROS↓, selectivity↑, angioG↓, MMPs↓, NF-kB↓, ITGB3↓, NADPH↓,
272- ALA,    Evidence that α-lipoic acid inhibits NF-κB activation independent of its antioxidant function
- in-vitro, NA, HUVECs
NF-kB↓,
1078- And,    Andrographolide inhibits breast cancer through suppressing COX-2 expression and angiogenesis via inactivation of p300 signaling and VEGF pathway
- in-vitro, BC, MDA-MB-231 - in-vitro, Nor, HUVECs - in-vivo, BC, MCF7 - in-vitro, BC, T47D - in-vitro, BC, BT549 - in-vitro, BC, MDA-MB-361
TumCP↓, COX2/PTGS2↓, *angioG↓, Cyt‑c↑, CREB2↓, cFos↓, NF-kB↓, HATs↓, cl‑Casp3↑, cl‑Casp9↑, Bax:Bcl2↑, Apoptosis↑, *toxicity↓,
6393- ANE,    Anethole in cancer therapy: Mechanisms, synergistic potential, and clinical challenges
- Review, Var, NA
AntiCan↑, Apoptosis↑, TumCCA↑, TumCP↓, angioG↓, NF-kB↓, PI3K↓, Akt↓, mTOR↓, Casp↓, ChemoSen↑,
6394- ANE,    Anethole blocks both early and late cellular responses transduced by tumor necrosis factor: effect on NF-kappaB, AP-1, JNK, MAPKK and apoptosis
TNF-α↓, NF-kB↓, Casp↑, tumCV↓,
6396- ANE,  FEO,    Anethole Inhibits the Proliferation of Human Prostate Cancer Cells via Induction of Cell Cycle Arrest and Apoptosis
- in-vitro, Pca, PC3
TumCP↓, TumCG↓, TumCMig↓, CSCs↓, ROS↑, MPT↑, Casp3↑, Casp9↑, DNAdam↑, cl‑PARP↑, Bax:Bcl2↑, TumCCA↑, cycD1/CCND1↓, CDK4↓, cMyc↓, P21↑, p27/CDKN1B↑, NF-kB↓, eff↑,
6397- ANE,  Cisplatin,    Synergistic Effect of Anethole and Platinum Drug Cisplatin against Oral Cancer Cell Growth and Migration by Inhibiting MAPKase, Beta-Catenin, and NF-κB Pathways
- in-vitro, SCC, Ca9-22
AntiCan↑, ChemoSen↑, TumCP↓, MMP↓, ROS↑, MAPK↓, β-catenin/ZEB1↓, NF-kB↓, EMT↓, Casp↑,
6401- ANE,    Anethole and Its Role in Chronic Diseases
- Review, Var, NA - Review, PSA, NA
*BioAv↝, *other↝, eff↓, TNF-α↓, IL10↑, CXCR4↓, MMP2↓, MMP9↓, TIMP1↑, NF-kB↓, AP-1↓, STAT↓, JNK↓, ERK↓, MAPK↓, PI3K↓, Akt↓, JAK↓, *AntiDiabetic↓, *neuroP↑, *Imm↑, chemoP↑, *AntiThr↑, *AntiAg↑, *antiOx↑, *SOD↑, *GSH↑, *Wound Healing↑, chemoPv↑, *GSTs↑, *NF-kB↓,
7907- Api,  IVT,    Anticancer Potential of Apigenin and Isovitexin with Focus on Oncogenic Metabolism in Cancer Stem Cells
- Review, Var, NA
ChemoSen↑, CSCs↓, Wnt↓, β-catenin/ZEB1↓, PI3K↓, MMP↓, TumMeta↓, MAPK↓, VEGF↓, MMP9↓, TGF-β↓, Inflam↓, COX2/PTGS2↓, IL6↓, NF-kB↓, TumCCA↑, P53↑, cycD1/CCND1↓, BAX↑, Casp↓, Bcl-2↓, CD133↓, Nanog↓, SOX2↓, Akt↓, TumCP↓, TumCMig↓, YAP/TEAD↓, CCN2/CTGF↓, CCN1/CYR61↓, SIRT3↓, SIRT6↓, PCNA↓, DNMT1↓, miR-34a↑,
1095- Api,    Apigenin inhibits epithelial-mesenchymal transition of human colon cancer cells through NF-κB/Snail signaling pathway
- Analysis, Colon, NA
Snail↓, EMT↓, NF-kB↓,
581- Api,  Cisplatin,    The natural flavonoid apigenin sensitizes human CD44+ prostate cancer stem cells to cisplatin therapy
- in-vitro, Pca, CD44+
Bcl-2↓, survivin↓, Casp8↑, P53↑, Sharpin↓, APAF1↑, p‑Akt↓, NF-kB↓, P21↑, Cyc↓, CDK2↓, CDK4/6↓, Snail↓, ChemoSen↑,
589- Api,  5-FU,    Interactions between dietary flavonoids apigenin or luteolin and chemotherapeutic drugs to potentiate anti-proliferative effect on human pancreatic cancer cells, in vitro
- in-vitro, PC, Bxpc-3
GSK‐3β↓, NF-kB↓,
211- Api,    Suppression of NF-κB and NF-κB-Regulated Gene Expression by Apigenin through IκBα and IKK Pathway in TRAMP Mice
- in-vivo, Pca, NA
IKKα↓, NF-kB↓, cycD1/CCND1↓, COX2/PTGS2↓, Bcl-2↓, Bcl-xL↓, VEGF↓, PCNA↓, BAX↑,
171- Api,    Apigenin in cancer therapy: anti-cancer effects and mechanisms of action
- Review, Var, NA
PI3K/Akt↓, NF-kB↓, CK2↓, FOXO↓, MAPK↝, ERK↓, p‑JAK↓, Wnt/(β-catenin)↓, ROS↑, CDC25↓, p‑STAT↓, DNAdam↑,
240- Api,    The flavonoid apigenin reduces prostate cancer CD44(+) stem cell survival and migration through PI3K/Akt/NF-κB signaling
- in-vitro, Pca, PC3 - in-vitro, Pca, CD44+
P21↑, p27/CDKN1B↑, Casp3↑, Casp8↑, Slug↓, Snail↓, NF-kB↓, PI3K↓, Akt↓,
237- Api,    Apigenin blocks IKKα activation and suppresses prostate cancer progression
- in-vivo, Pca, PC3 - in-vivo, Pca, 22Rv1 - in-vivo, Pca, LNCaP - in-vivo, Pca, DU145
IKKα↓, NF-kB↓,
416- Api,    In Vitro and In Vivo Anti-tumoral Effects of the Flavonoid Apigenin in Malignant Mesothelioma
- vitro+vivo, NA, NA
Bax:Bcl2↑, P53↑, ROS↑, Casp9↑, Casp8↑, cl‑PARP1↑, p‑ERK⇅, p‑JNK↓, p‑p38↑, p‑Akt↓, cJun↓, NF-kB↓, EGFR↓, TumCCA↑,
2639- Api,    Plant flavone apigenin: An emerging anticancer agent
- Review, Var, NA
*antiOx↑, *Inflam↓, AntiCan↑, ChemoSen↑, BioEnh↑, chemoPv↑, IL6↓, STAT3↓, NF-kB↓, IL8↓, eff↝, Akt↓, PI3K↓, HER2/EBBR2↓, cycD1/CCND1↓, CycD3↓, p27/CDKN1B↑, FOXO3↑, STAT3↓, MMP2↓, MMP9↓, VEGF↓, Twist↓, MMP↓, ROS↑, NADPH↑, NRF2↓, SOD↓, COX2/PTGS2↓, p38↑, Telomerase↓, HDAC↓, HDAC1↓, HDAC3↓, Hif1a↓, angioG↓, uPA↓, Ca+2↑, Bax:Bcl2↑, Cyt‑c↑, Casp9↑, Casp12↑, Casp3↑, cl‑PARP↑, E-cadherin↑, β-catenin/ZEB1↓, cMyc↓, CDK4↓, CDK2↓, CDK6↓, IGF-1↓, CK2↓, CSCs↓, FAK↓, Gli↓, GLUT1↓,
2319- Api,    Apigenin sensitizes radiotherapy of mouse subcutaneous glioma through attenuations of cell stemness and DNA damage repair by inhibiting NF-κB/HIF-1α-mediated glycolysis
- in-vitro, GBM, NA
Glycolysis↓, NF-kB↓, p65↓, Hif1a↓, GLUT1↓, GLUT3↓, PKM2↓, RadioS↑, TumVol↓, TumW↓,
1149- Api,    Apigenin inhibits colonic inflammation and tumorigenesis by suppressing STAT3-NF-κB signaling
- vitro+vivo, IBD, NA
COX2/PTGS2↓, MPO↓, NF-kB↓, STAT3↓, Inflam↓,
1547- Api,    Apigenin: Molecular Mechanisms and Therapeutic Potential against Cancer Spreading
- Review, NA, NA
angioG↓, EMT↓, CSCs↓, TumCCA↑, Dose∅, ROS↑, MMP↓, Catalase↓, GSH↓, PI3K↓, Akt↓, NF-kB↓, OCT4↓, Nanog↓, SIRT3↓, SIRT6↓, eff↑, eff↑, Cyt‑c↑, Bax:Bcl2↑, p‑GSK‐3β↓, FOXO3↑, p‑STAT3↓, MMP2↓, MMP9↓, COX2/PTGS2↓, MMPs↓, NRF2↓, HDAC↓, Telomerase↓, eff↑, eff↑, eff↑, eff↑, eff↑, XIAP↓, survivin↓, CK2↓, HSP90↓, Hif1a↓, FAK↓, EMT↓,
1560- Api,    Apigenin as an anticancer agent
- Review, NA, NA
Apoptosis↑, Casp3∅, Casp8∅, TNF-α∅, Cyt‑c↑, MMP2↓, MMP9↓, Snail↓, Slug↓, NF-kB↓, p50↓, PI3K↓, Akt↓, p‑Akt↓,
1564- Api,    Apigenin-induced prostate cancer cell death is initiated by reactive oxygen species and p53 activation
- in-vitro, Pca, 22Rv1 - in-vivo, NA, NA
MDM2↓, NF-kB↓, p65↓, P21↑, ROS↑, GSH↓, MMP↓, Cyt‑c↑, Apoptosis↑, P53↑, eff↓, Bcl-xL↓, Bcl-2↓, BAX↑, Casp↑, TumCG↓, TumVol↓, TumW↓,
3382- ART/DHA,    Repurposing Artemisinin and its Derivatives as Anticancer Drugs: A Chance or Challenge?
- Review, Var, NA
AntiCan↑, toxicity↑, Ferroptosis↑, ROS↑, TumCCA↑, BioAv↝, eff↝, Half-Life↓, Ferritin↓, GPx4↓, NADPH↓, GSH↓, BAX↑, Cyt‑c↑, cl‑Casp3↑, VEGF↓, IL8↓, COX2/PTGS2↓, MMP9↓, E-cadherin↑, MMP2↓, NF-kB↓, p16↑, CDK4↓, cycD1/CCND1↓, p62↓, LC3II↑, EMT↓, CSCs↓, Wnt↓, β-catenin/ZEB1↓, uPA↓, TumAuto↑, angioG↓, ChemoSen↑,
3391- ART/DHA,    Antitumor Activity of Artemisinin and Its Derivatives: From a Well-Known Antimalarial Agent to a Potential Anticancer Drug
- Review, Var, NA
TumCP↓, TumMeta↓, angioG↓, TumVol↓, BioAv↓, Half-Life↓, BioAv↑, eff↑, eff↓, ROS↑, selectivity↑, TumCCA↑, survivin↓, BAX↑, Casp3↓, Casp8↑, Casp9↑, CDC25↓, CycB/CCNB1↓, NF-kB↓, cycD1/CCND1↓, cycE/CCNE↓, E2Fs↓, P21↑, p27/CDKN1B↑, ADP:ATP↑, MDM2↓, VEGF↓, IL8↓, COX2/PTGS2↓, MMP9↓, ER Stress↓, cMyc↓, GRP78/BiP↑, DNAdam↑, AP-1↓, MMP2↓, PKCδ↓, Raf↓, ERK↓, JNK↓, PCNA↓, CDK2↓, CDK4↓, TOP2↓, uPA↓, MMP7↓, TIMP2↑, Cdc42↑, E-cadherin↑,
556- ART/DHA,    Artemisinins as a novel anti-cancer therapy: Targeting a global cancer pandemic through drug repurposing
- Review, NA, NA
IL6↓, IL1↓, TNF-α↓, TGF-β↓, NF-kB↓, MIP2↓, PGE2↓, NO↓, Hif1a↓, VEGFR2/KDR/Flk1↓, VEGF↓, MMP2↓, TIMP2↑, ITGB1↑, NCAM↑, p‑ATM↑, p‑ATR↑, p‑CHK1↑, p‑Chk2↑, Wnt/(β-catenin)↓, PI3K↓, Akt↓, ERK↓, cMyc↓, mTOR↓, survivin↓, cMET↓, EGFR↓, cycD1/CCND1↓, cycE1↓, CDK4/6↓, p16↑, p27/CDKN1B↑, Apoptosis↑, TumAuto↑, Ferroptosis↑, oncosis↑, TumCCA↑, ROS↑, DNAdam↑, RAD51↓, HR↓,
558- ART/DHA,    Artemisinin and Its Synthetic Derivatives as a Possible Therapy for Cancer
- Review, NA, NA
ROS↑, oncosis↑, Apoptosis↑, LysoPr↑, TumAuto↑, Wnt/(β-catenin)↑, AMP↓, NF-kB↓, Myc↓, CREBBP↓, mTOR↓, E-cadherin↑,
5136- ART/DHA,    Dihydroartemisinin targets VEGFR2 via the NF-κB pathway in endothelial cells to inhibit angiogenesis
- in-vitro, Var, NA
angioG↓, TumCP↓, TumCMig↓, NF-kB↓,
5134- ART/DHA,    Dihydroartemisinin induces autophagy by suppressing NF-κB activation
- in-vitro, Var, NA
TumAuto↑, NF-kB↓, ChemoSen↑,
2324- ART/DHA,    Research Progress of Warburg Effect in Hepatocellular Carcinoma
- Review, Var, NA
PKM2↓, GLUT1↓, Glycolysis↓, Akt↓, mTOR↓, Hif1a↓, HK2↓, LDH↓, NF-kB↓,
1142- Ash,    Ashwagandha-Induced Programmed Cell Death in the Treatment of Breast Cancer
- Review, BC, MCF7 - NA, BC, MDA-MB-231 - NA, Nor, HMEC
Apoptosis↑, ROS↑, DNAdam↑, OXPHOS↓, *ROS∅, Bcl-2↓, XIAP↓, survivin↓, DR5↑, IKKα↓, NF-kB↓, selectivity↑, *ROS∅, eff↓, Paraptosis↑,
5396- Ash,    Withania Somnifera (Ashwagandha) and Withaferin A: Potential in Integrative Oncology
- Review, Var, NA
selectivity↑, ROS↑, Apoptosis↑, ChemoSen↑, RadioS↑, NF-kB↓, ER-α36↓, P53↑, *ROS∅, γH2AX↑, DNAdam↑, MMP↓, XIAP↓, IAP1↓, survivin↓, SOD↓, Dose↝, IL6↓, TNF-α↓, COX2/PTGS2↓, p‑Akt↓, NOTCH1↓, FOXO↑, Casp↑, MMP2↓, CSCs↓, *ROS↓, *SOD2↑, chemoP↑, ChemoSen↑, RadioS↑,
3174- Ash,    Withaferin A Acts as a Novel Regulator of Liver X Receptor-α in HCC
- in-vitro, HCC, HepG2 - in-vitro, HCC, Hep3B - in-vitro, HCC, HUH7
NF-kB↓, angioG↓, Inflam↓, TumCP↓, TumCMig↓, TumCI↓, Sp1/3/4↓, VEGF↓, angioG↓, uPA↓, PDGF↓, MCP1/CCL2↓, ICAM-1↓, *NRF2↑, *hepatoP↑,
3155- Ash,    Overview of the anticancer activity of withaferin A, an active constituent of the Indian ginseng Withania somnifera
- Review, Var, NA
Half-Life↝, Inflam↓, antiOx↓, angioG↓, ROS↑, BAX↑, Bak↑, E6↓, E7↓, P53↑, Casp3↑, cl‑PARP↑, STAT3↓, eff↑, HSP90↓, TGF-β↓, TNF-α↓, EMT↑, mTOR↓, NOTCH1↓, p‑Akt↓, NF-kB↓, Dose↝,

Showing Research Papers: 1 to 50 of 645
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 645

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

AApath↓, 1,   AKR1B10↓, 1,   AntiBio↓, 1,   ASAP2↓, 1,   BMP7/OP1↓, 1,   CCN1/CYR61↓, 1,   CDK7↓, 1,   compII↓, 1,   compV↓, 1,   CTSK↓, 1,   CUL1↝, 1,   CUL5↝, 1,   CX43/GJA1↓, 1,   CXCR3↓, 1,   DDIT4↑, 1,   ERCC3↑, 1,   HES1↓, 1,   HLA-I/II↑, 1,   IL7↓, 1,   IQGAP3↓, 1,   IRes↓, 1,   IRF1↑, 1,   LRIG1↑, 1,   miR-107↑, 2,   miR-134↑, 1,   miR-224↓, 2,   miR-422a↑, 2,   miR-590-3p↑, 1,   MMP16↓, 3,   MTA1↓, 1,   MYCN↓, 1,   NA↑, 3,   NAT↓, 1,   NOD1↓, 1,   O-Glc↓, 1,   PA↑, 1,   PLA2↓, 1,   PRKCQ/PKCθ↓, 1,   PSEN1/PS1↓, 1,   PTN↓, 1,   SERPINH1/HSP47↓, 1,   XRCC1↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 3,   antiOx↑, 19,   antiOx⇅, 1,   ARE↓, 1,   ATF3↓, 1,   ATF3↑, 3,   Catalase↓, 7,   Catalase↑, 4,   compI↓, 2,   Copper↓, 1,   CYP1A1↓, 3,   CYP1A1↑, 2,   CYP2E1↑, 1,   Fenton↑, 1,   Ferroptosis↓, 1,   Ferroptosis↑, 12,   frataxin↑, 1,   GCLM↓, 1,   GPx↓, 1,   GPx↑, 7,   GPx1↓, 1,   GPx4↓, 9,   GSH↓, 36,   GSH↑, 9,   GSH/GSSG↓, 2,   GSR↓, 4,   GSR↑, 3,   ox-GSSG↑, 1,   GSTA1↓, 1,   GSTA1↑, 2,   GSTP1/GSTπ↑, 1,   GSTs↓, 5,   GSTs↑, 4,   GSTs↝, 1,   H2O2↑, 6,   HK1↓, 1,   HO-1↓, 11,   HO-1↑, 26,   HO-1↝, 1,   HO-2↓, 1,   ICD↑, 1,   Iron↑, 3,   i-Iron↑, 1,   Keap1↓, 1,   Keap1↑, 1,   ox-Keap1↓, 1,   rd-Keap1↑, 1,   lipid-P?, 1,   lipid-P↓, 10,   lipid-P↑, 12,   MAD↓, 1,   MDA↓, 3,   MDA↑, 5,   MPO↓, 3,   NADH↓, 1,   NOX4↑, 1,   NQO1↓, 3,   NQO1↑, 6,   NRF2↓, 26,   NRF2↑, 36,   NRF2↝, 2,   NRF2∅, 1,   p‑NRF2↓, 1,   OXPHOS↓, 5,   PAO↑, 1,   Prx↓, 1,   Prx↑, 1,   Prx4↑, 1,   PrxII↓, 1,   PYCR1↓, 1,   ROS?, 1,   ROS↓, 42,   ROS↑, 263,   ROS⇅, 9,   ROS↝, 1,   ROS∅, 1,   i-ROS↓, 1,   i-ROS↑, 3,   mt-ROS↑, 5,   SIRT3↓, 3,   SIRT3↑, 5,   SOD?, 1,   SOD↓, 11,   SOD↑, 11,   SOD1↓, 1,   SOD1↑, 1,   SOD2↓, 6,   SOD2↑, 2,   TAC↓, 2,   TBARS↑, 1,   Thiols↓, 3,   i-Thiols↓, 1,   TKT↝, 1,   Trx↓, 2,   Trx1↑, 1,   TrxR↓, 12,   TrxR1↓, 3,   VitC↓, 1,   VitE↓, 1,   xCT/SLC7A11↓, 3,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   FTH1↓, 1,   IronCh↑, 3,   IronCh∅, 1,   Tf↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ADP:ATP↑, 1,   AIF↑, 13,   ATP↓, 18,   mt-ATP↓, 1,   Bfl-1↓, 1,   BOK↑, 1,   CDC2↓, 8,   CDC2↑, 1,   CDC25↓, 9,   compIII↓, 1,   EGF↓, 6,   ETC↓, 2,   FGFR1↓, 2,   Insulin↓, 1,   MEK↓, 7,   p‑MEK↓, 2,   mitResp↓, 3,   mitResp↑, 2,   MKK4↓, 1,   MKK7↓, 1,   MKP5↑, 1,   MMP↓, 122,   MMP↝, 1,   MPT↑, 4,   mtDam↑, 20,   OCR↓, 7,   OCR↑, 1,   p‑p42↓, 1,   Raf↓, 7,   p‑Raf↓, 1,   c-Raf↓, 1,   SDH↑, 1,   XIAP?, 1,   XIAP↓, 50,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 3,   ACC↓, 1,   ACC↑, 4,   ACLY↓, 1,   ACSL4↑, 1,   AKT1↓, 2,   ALAT↓, 4,   ALAT↝, 1,   ALDOA↓, 1,   AMP↓, 2,   AMPK↓, 1,   AMPK↑, 32,   p‑AMPK↑, 2,   ANXA7↑, 2,   ATG7↑, 2,   CAIX/CA9↓, 1,   CAIX/CA9↑, 1,   cAMP↓, 1,   CholSyn↓, 1,   cMyc↓, 54,   cMyc↑, 2,   p‑cMyc↑, 1,   CREB↓, 4,   CYP3A4↓, 1,   ECAR↓, 2,   ECAR↝, 1,   ENO1↓, 1,   FAO↑, 1,   FASN↓, 9,   FASN↑, 1,   G6PD↓, 2,   GAPDH↓, 1,   GLS↓, 1,   glucose↝, 1,   GlucoseCon↓, 11,   Glycolysis↓, 34,   H2S↑, 1,   HK2↓, 23,   IR↓, 1,   lactateProd↓, 11,   lactateProd↑, 1,   LDH↓, 10,   LDH↑, 2,   LDH↝, 3,   i-LDH↓, 1,   LDHA↓, 13,   LDL↓, 2,   lipoGen↓, 1,   MCT4↓, 2,   NADPH↓, 3,   NADPH↑, 4,   PCK1↓, 1,   PDH↑, 1,   PDH↝, 1,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 7,   PDK3↑, 1,   PFK↓, 5,   PFK1↓, 2,   PI3K/Akt↓, 8,   PI3k/Akt/mTOR↓, 1,   PKM2↓, 19,   PPARα↓, 2,   PPARα↝, 1,   cl‑PPARα↓, 1,   PPARγ↓, 4,   PPARγ↑, 10,   Pyruv↓, 1,   R5P↝, 1,   SCD1↓, 1,   SIRT1↓, 11,   SIRT1↑, 15,   SIRT2↓, 1,   SREBP1/SREBF1↓, 2,   SREBP2↓, 2,   SSAT↑, 1,   STK11/LKB1↑, 1,   TCA↓, 1,   TS↓, 1,   Warburg↓, 9,  

Cell Death(tgid=5) ⓘ

AhR↓, 1,   AhR↑, 1,   Akt↓, 205,   Akt↑, 9,   p‑Akt↓, 48,   p‑Akt↑, 1,   APAF1↑, 8,   Apoptosis?, 3,   Apoptosis↓, 6,   Apoptosis↑, 248,   m-Apoptosis↑, 1,   mt-Apoptosis↑, 3,   ASK1↑, 1,   ATF2↓, 5,   BAD↓, 5,   BAD↑, 12,   Bak↑, 12,   BAX↓, 3,   BAX↑, 133,   BAX⇅, 1,   BAX↝, 2,   Bax:Bcl2↑, 39,   Bcl-2↓, 156,   Bcl-2↑, 4,   Bcl-2↝, 1,   Bcl-xL↓, 58,   BID↓, 2,   BID↑, 7,   BIM↑, 9,   Casp↓, 3,   Casp↑, 41,   Casp∅, 1,   cl‑Casp↑, 2,   Casp1↓, 2,   Casp1↑, 1,   Casp10↑, 2,   Casp12?, 1,   Casp12↑, 1,   Casp12↝, 1,   cl‑Casp12↑, 1,   Casp2↑, 1,   Casp3↓, 5,   Casp3↑, 159,   Casp3↝, 1,   Casp3∅, 1,   cl‑Casp3↑, 29,   proCasp3↑, 1,   Casp6↑, 3,   Casp7↑, 16,   cl‑Casp7↑, 3,   Casp8↑, 47,   Casp8∅, 2,   cl‑Casp8↑, 6,   pro‑Casp8↑, 1,   Casp9↓, 3,   Casp9↑, 99,   p‑Casp9↑, 1,   cl‑Casp9↑, 15,   proCasp9↓, 1,   CBP↓, 3,   cFLIP↓, 7,   Chk2↓, 2,   Chk2↑, 1,   p‑Chk2↑, 1,   CK2↓, 5,   Cyt‑c↓, 3,   Cyt‑c↑, 95,   Cyt‑c↝, 1,   Diablo↑, 12,   DR4↑, 14,   DR5↑, 35,   Endon↑, 2,   FADD↑, 4,   Fas↓, 3,   Fas↑, 22,   FasL↓, 2,   FasL↑, 7,   FasL⇅, 1,   Ferroptosis↓, 1,   Ferroptosis↑, 12,   GSDME↑, 1,   HEY1↓, 1,   HGF/c-Met↓, 3,   hTERT/TERT↓, 15,   IAP1↓, 21,   IAP2/BIRC3↓, 12,   IAP2/BIRC3↑, 1,   iNOS↓, 31,   iNOS↑, 1,   JNK↓, 14,   JNK↑, 27,   p‑JNK↓, 7,   p‑JNK↑, 4,   JWA↑, 1,   MAPK↓, 60,   MAPK↑, 15,   MAPK↝, 1,   p‑MAPK↓, 2,   Mcl-1?, 1,   Mcl-1↓, 29,   Mcl-1↑, 2,   MCT1↓, 2,   MDM2↓, 12,   MDM2↑, 2,   p‑MDM2↓, 1,   MKP1↓, 1,   MKP2↓, 1,   MOMP↑, 2,   Myc↓, 10,   Myc↑, 1,   NAIP↓, 1,   Necroptosis↑, 4,   necrosis↑, 3,   NICD↓, 1,   NOXA↑, 5,   oncosis↑, 2,   p27/CDKN1B↓, 5,   p27/CDKN1B↑, 41,   p38↓, 9,   p38↑, 23,   p‑p38↓, 3,   p‑p38↑, 5,   Paraptosis↑, 2,   Proteasome?, 1,   Proteasome↓, 3,   PUMA↑, 7,   Pyro↑, 1,   RIP1↓, 1,   RIP1↑, 2,   Set9↑, 1,   survivin↓, 76,   survivin↑, 1,   Telomerase↓, 17,   TNFR 1↓, 1,   TNFR 1↑, 2,   TRAIL↑, 8,   TRAIL⇅, 1,   TRAILR↑, 6,   TumCD?, 1,   TumCD↓, 1,   TumCD↑, 16,   TumCD∅, 1,   YAP/TEAD↓, 3,  

Kinase & Signal Transduction(tgid=6) ⓘ

CaMKII ↓, 2,   cSrc↓, 4,   EF-1α↓, 1,   FOXD3↑, 2,   HCAR2↑, 1,   HER2/EBBR2↓, 16,   p‑HER2/EBBR2↓, 1,   p70S6↓, 2,   PAK↓, 1,   RET↓, 1,   RTK-RAS↓, 1,   SOX9?, 1,   SOX9↑, 2,   Sp1/3/4↓, 23,   Sp1/3/4↑, 1,   TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

cJun↓, 14,   cJun↑, 5,   p‑cJun↓, 1,   p‑cJun↑, 1,   EZH2↓, 5,   H3↓, 3,   H3↑, 2,   p‑H3↓, 1,   ac‑H3↑, 2,   H4↓, 1,   H4↑, 2,   ac‑H4↑, 1,   ac‑H4∅, 1,   HATs↓, 10,   HATs↑, 2,   HATs⇅, 1,   Matr↓, 1,   miR-21↓, 7,   miR-21↑, 1,   miR-218↑, 1,   miR-27a-3p↓, 1,   other↓, 6,   other↑, 3,   other↝, 10,   other∅, 1,   PCAF↓, 1,   PhotoS↑, 3,   pRB↓, 2,   pRB↑, 2,   p‑pRB↓, 5,   sonoS↑, 1,   TLE1↓, 1,   tumCV↓, 59,   tumCV∅, 1,   YMcells↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 22,   cl‑CHOP/DDIT3↑, 1,   eIF2α↓, 2,   eIF2α↑, 5,   p‑eIF2α↑, 2,   ER Stress↓, 2,   ER Stress↑, 39,   GRP78/BiP↓, 2,   GRP78/BiP↑, 11,   HSF1↓, 2,   HSP27↓, 6,   HSP27↝, 1,   HSP70/HSPA5↓, 6,   HSP70/HSPA5↑, 2,   HSP70/HSPA5↝, 1,   HSP90↓, 18,   HSPs↓, 1,   IRE1↑, 3,   PERK↑, 6,   p‑PERK↑, 1,   UPR↑, 4,   XBP-1↓, 1,   XBP-1↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 5,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 15,   BNIP3↑, 4,   LC3‑Ⅱ/LC3‑Ⅰ↑, 2,   LC3B↓, 1,   LC3B-II↑, 2,   LC3I↑, 1,   LC3II↓, 1,   LC3II↑, 16,   LC3s↑, 1,   p62↓, 6,   p62↑, 1,   SESN2↑, 1,   TumAuto↑, 46,   TumAuto↝, 1,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 3,   p‑ATM↑, 1,   p‑ATR↑, 1,   BRCA1↓, 1,   BRCA1↑, 1,   BRCA1↝, 1,   BRCA2↑, 1,   CHK1↓, 2,   CHK1↑, 1,   p‑CHK1↑, 2,   CYP1B1↑, 1,   DFF45↓, 2,   DFF45↑, 3,   DNAdam↓, 4,   DNAdam↑, 58,   DNArepair↓, 2,   DNArepair↑, 1,   DNMT1↓, 15,   DNMT3A↓, 3,   DNMT3B↓, 2,   DNMTs↓, 10,   DNMTs⇅, 1,   GADD45A↑, 2,   HR↓, 1,   MGMT↓, 1,   p16↑, 7,   P53?, 3,   P53↓, 6,   P53↑, 125,   P53↝, 3,   p‑P53↓, 1,   p‑P53↑, 3,   p53 Wildtype↑, 1,   p73↑, 1,   PARP↓, 8,   PARP↑, 18,   PARP↝, 1,   cl‑PARP↑, 72,   cl‑PARP1↑, 2,   PCNA↓, 34,   RAD51↓, 1,   SIRT6↓, 2,   SIRT6↑, 1,   TP53↓, 1,   TP53↑, 2,   UHRF1↓, 1,   γH2AX↓, 1,   γH2AX↑, 7,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 14,   CDK1↑, 3,   p‑CDK1↓, 1,   CDK2↓, 48,   CDK2↑, 2,   CDK4↓, 60,   CDK4↑, 1,   Cyc↓, 3,   cycA1/CCNA1↓, 10,   cycA1/CCNA1↑, 2,   CycB/CCNB1↓, 24,   CycB/CCNB1↑, 4,   cycD1/CCND1↓, 116,   cycD1/CCND1↑, 2,   cycD1/CCND1↝, 1,   CycD3↓, 3,   cycE/CCNE↓, 24,   cycE/CCNE↑, 2,   cycE1↓, 1,   E2Fs↓, 7,   mitA↑, 1,   p19↑, 1,   P21?, 1,   P21↓, 8,   P21↑, 85,   P21↝, 1,   RB1↓, 1,   RB1↑, 3,   p‑RB1↓, 6,   Securin↓, 2,   TFAP2A↓, 1,   TumCCA?, 2,   TumCCA↓, 11,   TumCCA↑, 199,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 12,   ALDH1A1↓, 3,   Axin2↑, 1,   BMI1↓, 1,   CD133↓, 10,   CD133↑, 1,   CD24↓, 3,   CD34↓, 3,   CD44↓, 18,   CDK8↓, 2,   CEBPB↓, 1,   cFos↓, 16,   cFos↑, 1,   CIP2A↓, 2,   cMET↓, 6,   p‑cMET↑, 1,   cMYB↓, 1,   CREB2↓, 1,   CREBBP↓, 1,   CSCs?, 1,   CSCs↓, 64,   CTNNB1↓, 1,   CTSB↓, 1,   CTSD↓, 1,   Diff↓, 1,   Diff↑, 4,   EIF4E↓, 1,   EMT↓, 96,   EMT↑, 2,   EP2↓, 1,   EpCAM↓, 3,   ERK↓, 78,   ERK↑, 6,   p‑ERK↓, 20,   p‑ERK↑, 1,   p‑ERK⇅, 1,   FGF↓, 3,   FGF↑, 1,   FLT3↓, 1,   FOXM1↓, 3,   FOXO↓, 2,   FOXO↑, 6,   FOXO1↓, 4,   FOXO1↑, 2,   FOXO3↓, 6,   FOXO3↑, 9,   FOXO3↝, 1,   p‑FOXO3↓, 1,   Gli↓, 1,   Gli1↓, 8,   GSK‐3β↓, 17,   GSK‐3β↑, 7,   p‑GSK‐3β↓, 6,   p‑GSK‐3β↑, 1,   HDAC↓, 29,   HDAC⇅, 1,   HDAC1↓, 7,   HDAC10↓, 1,   HDAC10↑, 1,   HDAC2↓, 3,   HDAC3↓, 6,   HDAC4↓, 1,   HDAC8↓, 5,   HH↓, 12,   HMGCR↓, 1,   HOXB-AS1↓, 1,   HRAS↓, 2,   IGF-1↓, 9,   IGF-1R↓, 4,   IGFBP1↑, 1,   IGFBP3↑, 2,   IGFR↓, 3,   Jun↓, 2,   p‑Jun↓, 1,   Let-7↑, 6,   LRP6↓, 1,   p‑MAP2K1/MEK1↓, 1,   miR-34a↑, 7,   miR-448↑, 1,   mTOR↓, 91,   p‑mTOR↓, 10,   mTORC1↓, 9,   mTORC2↓, 4,   n-MYC↓, 1,   Nanog↓, 9,   Nestin↓, 3,   NOTCH↓, 27,   NOTCH1↓, 18,   NOTCH1↑, 2,   NOTCH1↝, 1,   NOTCH3↓, 3,   NRAS↓, 1,   OCT4↓, 9,   p300↓, 4,   P70S6K↓, 4,   p‑P70S6K↓, 1,   P90RSK↓, 2,   PI3K↓, 152,   PI3K↑, 1,   p‑PI3K↓, 9,   PIAS-3↑, 1,   PTCH1↓, 5,   PTEN↓, 3,   PTEN↑, 34,   p‑PTEN↓, 1,   RAS?, 1,   RAS↓, 19,   RAS↑, 1,   SCF↓, 1,   Shh↓, 11,   SHP1↓, 1,   SHP1↑, 2,   Smo↓, 5,   SOX2↓, 7,   Src↓, 4,   p‑Src↓, 1,   STAT↓, 10,   p‑STAT↓, 1,   STAT1↓, 3,   p‑STAT1↓, 1,   STAT3↓, 105,   STAT3↑, 4,   p‑STAT3↓, 19,   STAT4↓, 1,   STAT5↓, 2,   STAT6↓, 2,   p‑STAT6↓, 1,   Sufu↓, 1,   SUZ12↓, 1,   TAZ↓, 1,   TCF↓, 2,   TCF↑, 1,   TCF-4↓, 3,   TK1↓, 1,   TOP1↓, 13,   TOP2↓, 7,   TOP2↑, 2,   TumCG↓, 102,   TumCG↑, 1,   Wnt?, 1,   Wnt↓, 69,   Wnt↑, 1,   Wnt/(β-catenin)↓, 7,   Wnt/(β-catenin)↑, 1,   ZFX↓, 1,  

Migration(tgid=13) ⓘ

5LO↓, 10,   AEG1↓, 1,   Akt2↓, 3,   AntiAg?, 1,   AP-1↓, 31,   AP-1↝, 1,   ATPase↓, 2,   AXL↓, 1,   BACH1↓, 1,   CA↓, 2,   Ca+2↓, 1,   Ca+2↑, 28,   Ca+2↝, 3,   i-Ca+2↑, 1,   CC(CDKs/cyclins)↓, 1,   CCN2/CTGF↓, 3,   CD11b↓, 1,   CD31/PECAM-1↓, 9,   Cdc42↓, 1,   Cdc42↑, 1,   CDK4/6↓, 3,   CEA↓, 2,   CLDN1↓, 1,   CLDN2↓, 1,   Cofilin↓, 1,   COL1↓, 1,   COL3A1↓, 1,   CXCL12↓, 1,   DLC1↑, 1,   E-cadherin↓, 5,   E-cadherin↑, 53,   EFEMP↓, 1,   ER-α36↓, 3,   F-actin↓, 1,   FAK↓, 25,   p‑FAK↓, 3,   p‑FAK↑, 1,   fascin↓, 1,   Fibronectin↓, 3,   FTO↓, 1,   GLI2↓, 3,   HLA↑, 1,   ITGA5↓, 2,   ITGB1↓, 6,   ITGB1↑, 1,   ITGB3↓, 1,   ITGB6↓, 1,   Ki-67↓, 30,   KRAS↓, 1,   LAMs↓, 4,   LEF1↓, 2,   LRP1↓, 1,   LysoPr↑, 1,   MALAT1↓, 4,   MET↓, 2,   MET↑, 1,   p‑MET↓, 1,   miR-133a-3p↑, 1,   miR-139-5p↑, 2,   miR-155↓, 4,   miR-19b↓, 1,   miR-200b↑, 2,   miR-200c↑, 2,   miR-203↑, 1,   miR-29b↓, 1,   miR-29b↑, 1,   miR-340↓, 2,   miR-384↑, 2,   MMP-10↓, 1,   MMP1↓, 10,   MMP13↓, 4,   MMP2↓, 120,   MMP3↓, 9,   MMP7↓, 18,   MMP9↓, 153,   MMP9↑, 3,   MMPs↓, 43,   MUC1-C↓, 1,   MUC4↓, 7,   N-cadherin↓, 31,   NCAM↑, 1,   NEDD9↓, 1,   p44↓, 1,   p‑p44↓, 1,   PAI-1/SERPINE1↓, 1,   PAK1↓, 1,   PDGF↓, 10,   PKA↓, 1,   PKCδ↓, 12,   Rac1↓, 3,   RAGE↓, 2,   RECK↑, 2,   Rho↓, 6,   Rho↑, 1,   Rho↝, 1,   RIP3↑, 2,   ROCK1↓, 5,   ROCK1↑, 2,   Sharpin↓, 1,   Slug↓, 11,   Smad1↑, 1,   p‑SMAD2↓, 1,   SMAD3↓, 2,   SMAD3↑, 1,   p‑SMAD3↓, 1,   SMAD4↓, 1,   Snail↓, 31,   SOX4↓, 1,   SOX4↑, 1,   SPARC↓, 1,   SPARC↑, 1,   STAC2↓, 1,   talin↓, 1,   TET1↓, 1,   TET1↑, 1,   TGF-β↓, 27,   TGF-β↑, 2,   TGF-β1↓, 1,   TIMP1↓, 4,   TIMP1↑, 10,   TIMP2↓, 3,   TIMP2↑, 11,   Treg lymp↓, 1,   TRIB3↑, 1,   TSP-1↑, 3,   TumCA↓, 5,   TumCI↓, 106,   TumCI↑, 1,   TumCMig↓, 95,   TumCMig↑, 2,   TumCP?, 2,   TumCP↓, 180,   TumCP↑, 2,   TumMeta↓, 91,   TumMeta↑, 6,   TumPF↓, 1,   Twist↓, 23,   Tyro3↓, 1,   uPA↓, 36,   uPAR↓, 5,   VCAM-1↓, 3,   VEGFR1↓, 3,   Vim↓, 45,   Vim↑, 1,   Zeb1↓, 12,   ZEB2↓, 1,   ZEB2↑, 1,   ZO-1↑, 3,   α-SMA↓, 3,   α-tubulin↓, 2,   β-catenin/ZEB1↓, 75,   β-catenin/ZEB1↑, 1,   p‑β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 132,   angioG↑, 2,   ATF4↓, 1,   ATF4↑, 9,   ATF4↝, 1,   ECM/TCF↓, 1,   EGFR↓, 58,   EGFR↑, 1,   p‑EGFR↓, 5,   EGR1↑, 1,   Endoglin↑, 1,   eNOS↓, 2,   eNOS↑, 1,   EPR↑, 3,   HIF-1↓, 10,   Hif1a↓, 75,   Hif1a↝, 1,   LOX1↓, 2,   miR-210↓, 1,   miR-34b-5p↑, 1,   NO↓, 9,   NO↑, 3,   NO↝, 1,   PDGFR-BB↓, 1,   PDGFR-BB↑, 1,   p‑PDGFR-BB↓, 1,   PHDs↓, 1,   VEGF↓, 158,   VEGF↑, 1,   VEGFR2/KDR/Flk1↓, 17,   p‑VEGFR2/KDR/Flk1↓, 1,   ZBTB10↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 11,   CTR1↑, 1,   GLUT1↓, 19,   GLUT1↑, 1,   GLUT3↓, 2,   GLUT3↑, 1,   GLUT4↓, 6,   NHE1↓, 2,   P-gp/ABCB1↓, 19,   SLC12A5↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

ASC↓, 1,   CB2 / CNR2↑, 1,   CD4+↓, 2,   CD4+↑, 3,   COX1↓, 7,   COX1↑, 1,   COX2/PTGS2↓, 179,   COX2/PTGS2↑, 1,   COX2/PTGS2↝, 1,   CRP↓, 2,   CXCc↓, 1,   CXCL1↓, 1,   CXCR2↓, 2,   CXCR4↓, 24,   FOXP3↓, 2,   GM-CSF↓, 2,   HCAR1↓, 1,   HCAR2↑, 1,   HMGB1↓, 5,   ICAM-1↓, 14,   IFN-γ↓, 4,   IFN-γ↑, 2,   IKKα↓, 29,   IKKα↑, 3,   p‑IKKα↓, 7,   IL1↓, 12,   IL1↑, 1,   IL10↓, 6,   IL10↑, 4,   IL12↓, 5,   IL12↑, 1,   IL17↓, 2,   IL18↓, 3,   IL1α↓, 1,   IL1β↓, 35,   IL1β↑, 1,   IL2↓, 7,   IL2↑, 6,   IL22↓, 1,   IL23↓, 1,   IL4↓, 4,   IL4↑, 2,   IL5↓, 1,   IL6↓, 83,   IL6↑, 1,   IL8↓, 18,   IL8↑, 2,   Imm↑, 15,   Imm↝, 1,   Inflam↓, 70,   Inflam↝, 1,   IRAK4↓, 1,   IκB↓, 4,   IκB↑, 4,   p‑IκB↓, 5,   p‑IκB↑, 2,   JAK↓, 13,   p‑JAK↓, 1,   JAK1↓, 7,   JAK1↑, 1,   JAK2↓, 17,   M1↓, 1,   MCP1/CCL2↓, 8,   MDSCs↓, 1,   MIP2↓, 2,   mPGES-1↓, 1,   MyD88↓, 1,   MyD88↑, 1,   NF-kB↓, 643,   NF-kB↑, 4,   p‑NF-kB↓, 8,   p‑NF-kB↑, 1,   NK cell↑, 5,   NK cell⇅, 1,   p50↓, 8,   p65↓, 26,   p65↑, 1,   p‑p65↓, 4,   p‑p65↑, 1,   ac‑p65↓, 1,   ac‑p65↑, 2,   PD-1↓, 3,   PD-L1↓, 10,   PD-L1↑, 1,   PGE1↓, 1,   PGE2↓, 31,   PSA↓, 9,   PSA∅, 1,   RANTES↓, 1,   SOCS-3↑, 1,   SOCS1↑, 2,   T-Cell↑, 2,   Th1 response↑, 1,   TLR2↓, 2,   TLR4↓, 14,   TLR4↑, 1,   TNF-α↓, 84,   TNF-α↑, 6,   TNF-α∅, 1,   TRAF1↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

pH↓, 1,   pH↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 2,   AChE↓, 1,   ADAM10↓, 1,   BChE↓, 1,  

Protein Aggregation(tgid=19) ⓘ

NLRP3↓, 7,   XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 24,   CDK6↓, 21,   CDK6↑, 1,   CYP19↓, 1,   ER(estro)↓, 2,   ERα/ESR1↓, 1,   ERβ/ESR2↑, 1,   EstroRS/ERS↓, 1,   GR↑, 1,   RANKL↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 2,   BioAv↓, 57,   BioAv↑, 58,   BioAv↝, 18,   BioAv∅, 1,   BioEnh?, 1,   BioEnh↑, 5,   ChemoSen↓, 4,   ChemoSen↑, 181,   ChemoSen⇅, 1,   ChemoSen↝, 1,   CYP1A2↓, 1,   CYP1A2↑, 1,   CYP2A3/CYP2A6↓, 1,   Dose?, 4,   Dose↓, 1,   Dose↑, 10,   Dose⇅, 1,   Dose↝, 49,   Dose∅, 11,   DrugR↓, 1,   eff↓, 38,   eff↑, 172,   eff↝, 8,   eff∅, 2,   Half-Life↓, 19,   Half-Life↑, 4,   Half-Life↝, 15,   Half-Life∅, 2,   MDR1↓, 8,   MRP1/ABCC1↓, 4,   P450↓, 7,   P450↝, 1,   RadioS↑, 78,   selectivity↑, 73,   TET2↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 4,   ALAT↝, 1,   ALC∅, 1,   ALP↓, 2,   ALP↝, 1,   AR↓, 24,   ascitic↓, 2,   AST↓, 4,   AST↝, 1,   BMPs↑, 2,   BRCA1↓, 1,   BRCA1↑, 1,   BRCA1↝, 1,   CA125↓, 1,   CEA↓, 2,   CRP↓, 2,   CYFRA21-1↓, 1,   E6↓, 4,   E7↓, 4,   EGFR↓, 58,   EGFR↑, 1,   p‑EGFR↓, 5,   ERα/ESR1↓, 1,   EstroRS/ERS↓, 1,   EZH2↓, 5,   Ferritin↓, 1,   FOXM1↓, 3,   GutMicro↑, 7,   GutMicro↝, 1,   HER2/EBBR2↓, 16,   p‑HER2/EBBR2↓, 1,   hTERT/TERT↓, 15,   IL6↓, 83,   IL6↑, 1,   Ki-67↓, 30,   KRAS↓, 1,   LDH↓, 10,   LDH↑, 2,   LDH↝, 3,   i-LDH↓, 1,   Myc↓, 10,   Myc↑, 1,   NOS2↓, 3,   NSE↓, 1,   PD-L1↓, 10,   PD-L1↑, 1,   PSA↓, 9,   PSA∅, 1,   RAGE↓, 2,   SUZ12↓, 1,   TP53↓, 1,   TP53↑, 2,   TRIB3↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↓, 3,   AntiCan↑, 58,   AntiCan∅, 1,   AntiDiabetic↑, 1,   antiNeop↑, 4,   AntiTum↓, 1,   AntiTum↑, 22,   cachexia↓, 2,   cardioP↑, 12,   CardioT↑, 1,   chemoP↑, 36,   chemoPv↑, 23,   ChemoSideEff↓, 9,   cognitive↑, 2,   hepatoP↓, 1,   hepatoP↑, 11,   NDRG1↑, 1,   neuroP↓, 1,   neuroP↑, 11,   NP/CIPN↓, 1,   Obesity↓, 1,   OS↑, 13,   Pain↓, 1,   QoL↑, 6,   radioP↑, 6,   Remission↑, 2,   RenoP↑, 8,   Risk↓, 14,   toxicity↓, 18,   toxicity↑, 4,   toxicity↝, 8,   toxicity∅, 5,   TumVol↓, 28,   TumVol∅, 1,   TumW↓, 14,   TumW∅, 1,   Weight↑, 1,   Weight∅, 2,   Wound Healing↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,   CD8+↑, 2,   Diar↓, 1,   Sepsis↓, 3,  
Total Targets: 1169

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

15-LOX/ALOX15↓, 1,   ACE/ACE1↓, 1,   ACE2↓, 1,   AntiBio↑, 7,   CYP2D6↓, 1,   diuretic↑, 1,   H+/K+-ATPase↓, 1,   IRes↝, 1,   Stroke↓, 4,   β-HEX↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx?, 1,   antiOx↓, 4,   antiOx↑, 89,   Bil↓, 1,   Catalase↓, 1,   Catalase↑, 32,   Ferroptosis↓, 2,   GPx↓, 1,   GPx↑, 24,   GPx1↑, 2,   GPx4↑, 1,   GSH↓, 1,   GSH↑, 38,   GSR↓, 1,   GSR↑, 4,   GSTA1↑, 2,   GSTs↑, 14,   H2O2↓, 3,   HDL↓, 1,   HNE↓, 1,   HO-1↓, 1,   HO-1↑, 18,   Iron∅, 1,   Keap1↑, 1,   Keap1↝, 1,   ox-Keap1↑, 1,   lipid-P↓, 26,   MDA↓, 16,   MDA↑, 1,   MFN2↑, 1,   MPO↓, 3,   MPO↑, 1,   NOX4↓, 1,   NQO1↑, 6,   Nrf1↑, 1,   NRF2↓, 1,   NRF2↑, 33,   Prx↑, 1,   RNS↓, 2,   ROS?, 1,   ROS↓, 89,   ROS↑, 2,   ROS∅, 3,   mt-ROS?, 1,   SIRT3↑, 1,   SOD↓, 1,   SOD↑, 36,   SOD1↑, 3,   SOD2↑, 3,   TAC↑, 4,   VitC↑, 1,   VitE↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 3,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↓, 2,   ATP↑, 3,   DRP1/DNM1L↓, 1,   Insulin↑, 1,   MEK↓, 1,   MMP↑, 3,   PGC-1α↑, 1,   PGC-1α↝, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 1,   12LOX↑, 1,   ALAT?, 1,   ALAT↓, 9,   AMPK↑, 5,   p‑AMPK↑, 1,   BUN↓, 1,   p‑cMyc↑, 1,   CREB↑, 1,   p‑CREB↑, 1,   cytoP450↓, 1,   glucose↓, 3,   GlucoseCon↑, 3,   GLUT2↑, 1,   H2S↑, 1,   LDH↓, 4,   LDH↑, 1,   LDHA↑, 1,   LDL↓, 3,   lipidLev↓, 2,   NAD↑, 1,   NADPH↓, 1,   NADPH↑, 1,   PPARα↑, 2,   PPARγ↓, 1,   PPARγ↑, 1,   p‑PPARγ↓, 1,   SIRT1↑, 4,   SREBP1/SREBF1↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 3,   Akt↑, 1,   Apoptosis↓, 2,   ATF2↑, 1,   BAX↓, 3,   Bcl-2↑, 1,   Casp1↓, 1,   Casp3?, 1,   Casp3↓, 8,   Casp9↓, 2,   Fas↓, 1,   Ferroptosis↓, 2,   iNOS↓, 11,   JNK↓, 2,   MAPK↓, 3,   MAPK↑, 1,   p38↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 4,   other↓, 1,   other↑, 1,   other↝, 5,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   ER Stress↓, 1,   HSP70/HSPA5↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 1,   LC3II↑, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 2,   p16↓, 1,   P53↓, 2,   PARP1↓, 1,   PCNA↓, 2,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 1,   cycD1/CCND1↓, 1,   cycE/CCNE↓, 1,   P21↓, 1,   RB1↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↓, 1,   ERK↑, 3,   FOXO3↑, 1,   GSK‐3β↓, 2,   GSK‐3β↑, 1,   HDAC↓, 2,   HDAC3↓, 1,   HH↓, 1,   IGF-1↑, 2,   p300↓, 1,   PDGFRB↓, 1,   PI3K↓, 3,   STAT↓, 1,   STAT3↓, 2,   STAT3↑, 1,   VGSC↓, 1,  

Migration(tgid=13) ⓘ

5LO↓, 4,   5LO↝, 1,   AntiAg↑, 10,   Ca+2↝, 2,   CEA↓, 1,   Ki-67↓, 1,   MMP13↓, 1,   MMP9↓, 1,   PAI-1/SERPINE1↓, 1,   PKCδ↑, 1,   p‑Rac1↓, 1,   Rho↓, 1,   TIMP1↓, 1,   TumCP↓, 1,   TXNIP↓, 1,   VCAM-1↓, 1,   ZO-1↑, 1,   α-SMA↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 2,   angioG↑, 1,   ATF4↓, 1,   Hif1a↓, 2,   NO↓, 7,   NO↑, 2,   PDGFR-BB↓, 1,   VEGF↓, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 7,   GLUT3↑, 2,   GLUT4↑, 3,   P-gp/ABCB1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 2,   COX2/PTGS2↓, 22,   COX2/PTGS2↑, 1,   CRP↓, 3,   IFN-γ↓, 3,   IKKα↑, 1,   IL1↓, 4,   IL10↓, 3,   IL10↑, 1,   IL12↓, 1,   IL17↓, 1,   IL18↓, 3,   IL1β↓, 15,   IL2↓, 3,   IL23↓, 1,   IL4↓, 1,   IL6↓, 22,   IL6↑, 1,   IL8↓, 6,   Imm↑, 4,   INF-γ↓, 1,   Inflam↓, 88,   Inflam↑, 3,   IκB?, 1,   pol-M2 MC↑, 1,   MCP1/CCL2↓, 1,   MyD88↓, 1,   NF-kB↓, 14,   NF-kB↑, 1,   PGE2↓, 7,   TLR2↓, 3,   TLR4↓, 4,   TNF-α↓, 27,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 2,   AChE↓, 8,   BDNF↑, 6,   ChAT↑, 1,   GABA↑, 2,   GABA↝, 1,   MAOA↓, 2,   NGF↑, 2,   tau↓, 1,   p‑tau↓, 2,   TrkB↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 6,   BACE/β-secretase↓, 1,   NLRP3↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

GR↓, 1,   TSHR↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 33,   BioAv↑, 30,   BioAv⇅, 1,   BioAv↝, 19,   BioEnh↑, 2,   Dose↑, 1,   Dose↝, 10,   Dose∅, 1,   eff↑, 13,   Half-Life↓, 1,   Half-Life↑, 1,   Half-Life↝, 7,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT?, 1,   ALAT↓, 9,   ALP↓, 3,   AST↓, 10,   Bil↓, 1,   BMD↑, 1,   BP↓, 1,   CEA↓, 1,   creat↓, 1,   CRP↓, 3,   GutMicro↑, 8,   IL6↓, 22,   IL6↑, 1,   Ki-67↓, 1,   LDH↓, 4,   LDH↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   antiAll↑, 1,   AntiArt↑, 5,   AntiCan↓, 1,   AntiCan↑, 10,   antiCG↑, 1,   antiD↓, 1,   AntiDiabetic↓, 1,   AntiDiabetic↑, 14,   antiPs↑, 1,   AntiTum↓, 1,   AntiTum↑, 1,   cardioP↑, 23,   cardioP⇅, 1,   chemoP↑, 6,   chemoPv↑, 8,   cognitive↓, 1,   cognitive↑, 11,   hepatoP↑, 31,   memory?, 1,   memory↑, 11,   motorD↑, 2,   neuroP?, 1,   neuroP↑, 57,   Obesity↓, 4,   OS↑, 1,   Pain↓, 4,   radioP↑, 9,   RenoP↑, 10,   Risk↓, 1,   toxicity↓, 24,   toxicity↑, 2,   toxicity↝, 5,   toxicity∅, 4,   Wound Healing↑, 4,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↓, 1,   AntiFungal↑, 2,   AntiViral↑, 6,   Bacteria↓, 15,   Bacteria↑, 1,   Diar↓, 2,   IRF3↓, 1,   Sepsis↓, 2,  
Total Targets: 307

Scientific Paper Hit Count for: NF-kB, Nuclear factor kappa B
52 Curcumin
26 Thymoquinone
23 Fisetin
18 EGCG (Epigallocatechin Gallate)
18 Resveratrol
17 Propolis -bee glue
15 Apigenin (mainly Parsley)
15 Garcinol
14 Betulinic acid
14 Sulforaphane (mainly Broccoli)
13 Ashwagandha(Withaferin A)
13 Eugenol
13 Lycopene
12 Baicalein
11 Quercetin
11 Luteolin
10 Boswellia (frankincense)
10 Honokiol
10 Shikonin
8 Phenethyl isothiocyanate
7 Cisplatin
7 Artemisinin
7 Caffeic Acid Phenethyl Ester (CAPE)
7 Disulfiram
7 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
7 Nimbolide
6 Radiotherapy/Radiation
6 Berberine
6 Chrysin
6 Deguelin
6 Emodin
6 Hyperoside
6 Kaempferol
6 Magnolol
6 Parthenolide
6 Pterostilbene
6 Silymarin (Milk Thistle) silibinin
5 Silver-NanoParticles
5 Anethole/trans-Anethole
5 Caffeic acid
5 Capsaicin
5 Celastrol
5 Crocetin
5 Copper and Cu NanoParticles
5 Ellagic acid
5 Gambogic Acid
5 Graviola
5 Indole-3-carbinol
5 Isoliquiritigenin
5 Rosmarinic acid
5 Selenite (Sodium)
4 Docetaxel
4 Beta-Caryophyllene
4 Hydroxycinnamic-acid
4 Cynaropicrin
4 Paclitaxel/Taxol
4 Hibiscus sabdariffa
4 HydroxyTyrosol
4 Inositol
4 isoorientin
4 Piperlongumine
4 Vitamin K2
3 Auranofin
3 Astragalus
3 Citric Acid
3 Allicin (mainly Garlic)
3 Alpha-Lipoic-Acid
3 Gemcitabine (Gemzar)
3 Bromelain
3 Chemotherapy
3 Cinnamon
3 Ginger/6-Shogaol/Gingerol
3 Dandelion Root
3 Piperine
3 Formononetin
3 lambertianic acid
3 Licochalcone A
3 Licorice
3 Lutein
3 Oleuropein
3 Sulfasalazine
3 Ursolic acid
3 Urolithin
2 Isovitexin
2 immunotherapy
2 Berbamine
2 Brucea javanica
2 brusatol
2 Zinc
2 Cat’s Claw
2 Celecoxib
2 Centella asiatica / Gotu kola → asiaticoside
2 Chlorogenic acid
2 Chocolate
2 Photodynamic Therapy
2 CUSP9
2 Docosahexaenoic Acid
2 Ginkgo biloba-EGb 761
2 Eurycomanone
2 Evodiamine
2 Genistein (soy isoflavone)
2 Geraniol
2 Grapeseed extract
2 Hydrogen Gas
2 Inulin Prebiotic
2 Ivermectin
2 Naringin
2 Niclosamide (Niclocide)
2 Marjoram (Origanum majorana)
2 xanthohumol
2 Plumbagin
2 Psoralidin
2 salinomycin
2 Vitamin C (Ascorbic Acid)
1 2-DeoxyGlucose
1 Magnetic Fields
1 Andrographis
1 Fennel Oil/Foeniculum vulgare
1 5-fluorouracil
1 Astaxanthin
1 Arctigenin
1 beta-glucans
1 Baicalin
1 Biochanin A
1 Bufalin/Huachansu
1 borneol
1 Bruteridin(bergamot juice)
1 α-Bisabolol / Chamomile oil
1 Butyrate
1 Carvacrol
1 Carnosine
1 Chlorophyllin
1 Cynara scolymus/Globe Artichoke/Artichoke Extract
1 Oxygen, Hyperbaric
1 methylseleninic acid
1 Cyclopamine
1 Diclofenac
1 Dipyridamole
1 eicosapentaenoic acid
1 Ferulic acid
1 Bortezomib
1 Flaxseed/Linseed
1 Ginkgolic acids
1 Ginkgo biloba
1 Ginkgolide B
1 Ginkgetin
1 Gossypol/AT-101
1 Proanthocyanidins
1 isoflavones
1 isoquercitrin
1 tumor necrosis factor-related apoptosis-inducing ligand
1 Lasiodin
1 Lactoferrin/Talactoferrin
1 Lemongrass Extract/Citral
1 SDG/lignans
1 Linalool
1 Melatonin
1 Methyl salicylate / Sweet Birch oil
1 Moringa oleifera
1 Neem
1 Oroxylin A
1 Orlistat
1 Phenylbutyrate
1 Propyl gallate
1 temozolomide
1 Polyphenols
1 Perilla
1 Rutin
1 buckwheat sprouts
1 Salvia officinalis
1 Sanguinarine
1 Aflavin-3,3′-digallate
1 Tomatine
1 Turmerones
1 Vitexin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:214  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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