TumCM/A Cancer Research Results

TumCM/A, Tumor cell metabolism/acidosis: Click to Expand ⟱
Source: HalifaxProj(normalize)
Type:
Acidosis in the Tumor Microenvironment
Lactic Acidosis: The increased glycolytic activity in tumors leads to the accumulation of lactic acid, resulting in a lower pH in the tumor microenvironment. This lactic acidosis can have several effects on tumor behavior and the surrounding tissue.
Scientific Papers found: Click to Expand⟱
9254- ISO, IH,    Isorhamnetin: what is the in vitro evidence for its antitumor potential and beyond?
- Review, Var, NA
MMP2↓, MMP9↓, MAPK↓, STAT3↓, Akt↓, mTOR↓, MEK↓, ERK↓, TumCP↓, TumCM/A↓, LDH↓, EMT↓, Casp3↑, Cyt‑c↑, BAX↑, cl‑Casp3↑, cl‑PARP↑, TumCCA?, AMPK↑, ROS↑, COX2/PTGS2↓, *cardioP↑, *hepatoP↑, *neuroP↑, *RenoP↑, *AntiViral↑, *antiCG↑, *AntiAg↑, *AntiThr↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

ROS↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 1,   TumCM/A↓, 1,  

Cell Death(tgid=5) ⓘ

BAX↑, 1,   Casp3↑, 1,   cl‑Casp3↑, 1,   Cyt‑c↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   ERK↓, 1,   MAPK↓, 1,   MEK↓, 1,   mTOR↓, 1,   STAT3↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

cl‑PARP↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA?, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

TumCP↓, 1,  

Migration(tgid=13) ⓘ

EMT↓, 1,   MMP2↓, 1,   MMP9↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,  

Clinical Biomarkers(tgid=22) ⓘ

LDH↓, 1,  
Total Targets: 21

Pathway results for Effect on Normal Cells:


Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,  

Functional Outcomes(tgid=23) ⓘ

antiCG↑, 1,   cardioP↑, 1,   hepatoP↑, 1,   neuroP↑, 1,   RenoP↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 1,  
Total Targets: 8

Scientific Paper Hit Count for: TumCM/A, Tumor cell metabolism/acidosis
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:325  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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