TumCMig Cancer Research Results

TumCMig, Tumor cell migration: Click to Expand ⟱
Source:
Type:
Tumor cell migration is a critical process in cancer progression and metastasis, which is the spread of cancer cells from the primary tumor to distant sites in the body.
Scientific Papers found: Click to Expand⟱
6465- 1,8-Cin,    Eucalyptol targets PI3K/Akt/mTOR pathway to inhibit skin cancer metastasis
- vitro+vivo, Melanoma, NA
TumMeta↓, TumCMig↓, TumCI↓, Vim↓, Snail↓, Slug↓, Twist↓, E-cadherin↓, EMT↓, MMP2↓, MMP9↓, PI3K↓, Akt↓, mTOR↓,
7857- 3BP,    A Mechanism of Isoorientin-Induced Apoptosis and Migration Inhibition in Gastric Cancer AGS Cells
- in-vitro, NA, AGS
tumCV↓, selectivity↑, *toxicity↓, Apoptosis↑, ROS↑, eff↓, TumCCA↑, p‑Akt↓, p‑GSK‐3β↓, β-catenin/ZEB1↓, TumCMig↓, Twist↓, N-cadherin↑, β-catenin/ZEB1↓, E-cadherin↑,
5465- AF,    The Thioredoxin Reductase Inhibitor Auranofin Suppresses Pulmonary Metastasis of Osteosarcoma, But Not Local Progression
- in-vitro, OS, NA
TrxR↓, ROS↑, TumCMig↓,
1333- AG,    Astragalus polysaccharide inhibits breast cancer cell migration and invasion by regulating epithelial-mesenchymal transition via the Wnt/β-catenin signaling pathway
- in-vitro, BC, NA
TumCMig↓, TumCI↓, Ki-67↓, TumCP↓, Snail↓, Vim↓, E-cadherin↑, Wnt↓, β-catenin/ZEB1↓,
5444- AG,    A Systematic Review of Phytochemistry, Pharmacology and Pharmacokinetics on Astragali Radix: Implications for Astragali Radix as a Personalized Medicine
- Review, Var, NA
*Imm↑, *antiOx↑, *Inflam↓, AntiTum↑, eff↑, chemoP↑, Dose↝, TumCMig↓, TumCP↓, Akt↓, GSK‐3β↓, MMP2↓, MMP9↓, EMT↓, PI3K↓, Akt↓, NF-kB↓, Inflam↓, TGF-β1↓, TNF-α↓, IL6↓, Fas↓, FasL↓, NOTCH1↓, JNK↓, TumCG↓,
5433- AG,    Mechanisms of astragalus polysaccharide enhancing STM2457 therapeutic efficacy in m6A-mediated OSCC treatment
- vitro+vivo, OS, NA
other↓, TumCP↓, TumCMig↓, TumCI↓, EMT↓, E-cadherin↑, N-cadherin↓, TumCG↓,
5438- AG,    Mechanisms of astragalus polysaccharide enhancing STM2457 therapeutic efficacy in mA-mediated OSCC treatment
- vitro+vivo, NA, NA
TumCP↓, TumCMig↓, TumCI↓, EMT↓, E-cadherin↑, N-cadherin↓,
4416- AgNPs,    Efficacy of curcumin-synthesized silver nanoparticles on MCF-7 breast cancer cells
- in-vitro, BC, MCF7
TumCMig↓, Apoptosis↑, BAX↑, P53↑, Bcl-2↓,
4555- AgNPs,    Silver nanoparticles from Dendropanax morbifera Léveille inhibit cell migration, induce apoptosis, and increase generation of reactive oxygen species in A549 lung cancer cells
- in-vitro, Lung, A549 - in-vitro, Liver, HepG2
*Bacteria↓, tumCV↓, selectivity↑, ROS↑, Apoptosis↑, TumCMig↓, AntiCan↑,
5147- AgNPs,    Size dependent anti-invasiveness of silver nanoparticles in lung cancer cells
- in-vitro, Lung, A549
TumCMig↓, TumCI↓, ROS↑, p‑NF-kB↑, selectivity↑, eff↝,
338- AgNPs,    Biogenic silver nanoparticles: In vitro and in vivo antitumor activity in bladder cancer
- vitro+vivo, Bladder, 5637
TumCD↑, Apoptosis↑, TumCMig↓, TumCP↓,
359- AgNPs,    Anti-cancer & anti-metastasis properties of bioorganic-capped silver nanoparticles fabricated from Juniperus chinensis extract against lung cancer cells
- in-vitro, Lung, A549 - in-vitro, Nor, HEK293
Casp3↑, Casp9↑, P53↑, ROS↑, MMP2↓, MMP9↓, TumCCA↑, *toxicity↓, TumCMig↓, TumCI↓,
5343- Ajoene,    The garlic compound ajoene covalently binds vimentin, disrupts the vimentin network and exerts anti-metastatic activity in cancer cells
- in-vitro, Cerv, HeLa - in-vitro, BC, MDA-MB-231
Vim↑, TumCI↓, TumCMig↓, TumMeta↓, Vim↓, other↝,
253- AL,    Allicin inhibits invasion and migration of breast cancer cells through the suppression of VCAM-1: Regulation of association between p65 and ER-α
- in-vitro, BC, MDA-MB-231
TumCMig↓, ERK↓, VCAM-1↓, NF-kB↓,
2660- AL,    Allicin: A review of its important pharmacological activities
- Review, AD, NA - Review, Var, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, AntiCan↑, *antiOx↑, *cardioP↑, *hepatoP↑, *BBB↑, *Half-Life↝, *H2S↑, *BP↓, *neuroP↑, *cognitive↑, *neuroP↑, *ROS↓, *GutMicro↑, *LDH↓, *ROS↓, *lipid-P↓, *antiOx↑, *other↑, *PI3K↓, *Akt↓, *NF-kB↓, *NO↓, *iNOS↓, *PGE2↓, *COX2/PTGS2↓, *IL6↓, *TNF-α↓, *MPO↓, *eff↑, *NRF2↑, *Keap1↓, *TBARS↓, *creat↓, *LDH↓, *AST↓, *ALAT↓, *MDA↓, *SOD↑, *GSH↑, *GSTs↑, *memory↑, chemoP↑, IL8↓, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Casp12↑, p38↑, Fas↑, P53↑, P21↑, CHK1↓, CycB/CCNB1↓, GSH↓, ROS↑, TumCCA↑, Hif1a↓, Bcl-2↓, VEGF↓, TumCMig↓, STAT3↓, VEGFR2/KDR/Flk1↓, p‑FAK↓,
3442- ALA,    α‑lipoic acid modulates prostate cancer cell growth and bone cell differentiation
- in-vitro, Pca, 22Rv1 - in-vitro, Pca, C4-2B - in-vitro, Nor, 3T3
tumCV↓, TumCMig↓, TumCI↓, ROS↑, Hif1a↑, JNK↑, Casp↑, TumCCA↑, Apoptosis↑, selectivity↑,
295- ALA,    α-Lipoic acid suppresses migration and invasion via downregulation of cell surface β1-integrin expression in bladder cancer cells
- in-vitro, Bladder, T24/HTB-9
ITGB1↓, TumCMig↓, ERK↓, Akt↓,
297- ALA,    Insights on the Use of α-Lipoic Acid for Therapeutic Purposes
- Review, BC, SkBr3 - Review, neuroblastoma, SK-N-SH - Review, AD, NA
PDH↑, TumCG↓, ROS↑, AMPK↑, EGR4↓, Half-Life↓, BioAv↝, *GSH↑, *IronCh↑, *ROS↓, *antiOx↑, *neuroP↑, *Ach↑, *lipid-P↓, *IL1β↓, *IL6↓, TumCP↓, FDG↓, Apoptosis↑, AMPK↑, mTOR↓, EGFR↓, TumCI↓, TumCMig↓, *memory↑, *BioAv↑, *BioAv↝, *other↓, *other↝, *Half-Life↓, *BioAv↑, *ChAT↑, *GlucoseCon↑,
276- ALA,    Alpha lipoic acid diminishes migration and invasion in hepatocellular carcinoma cells through an AMPK-p53 axis
- in-vitro, HCC, HepG2 - in-vitro, HCC, Hep3B
P53↑, EMT↓, AMPK↑, cycD1/CCND1↓, TumCMig↓,
1124- ALA,    Alpha lipoic acid inhibits proliferation and epithelial mesenchymal transition of thyroid cancer cells
- in-vitro, Thyroid, BCPAP - in-vitro, Thyroid, HTH-83 - in-vitro, Thyroid, CAL-62 - in-vitro, Thyroid, FTC-133 - in-vivo, NA, NA
TumCP↓, AMPK↑, mTOR↓, TumCMig↓, TumCI↓, EMT↓, E-cadherin↑, β-catenin/ZEB1↓, Vim↓, Snail↓, Twist↓, TGF-β↓, p‑SMAD2↓, TumCG↓,
7394- Amla,    Emblica officinalis extract downregulates pro-angiogenic molecules via upregulation of cellular and exosomal miR-375 in human ovarian cancer cells
- vitro+vivo, Ovarian, NA
antiNeop↑, TumCP↓, TumCMig↓, TumCI↓, TumCG↓, miR-375↑, IGFR↓, Snail↓, E-cadherin↑,
553- Anamu,    The anti-inflammatory and analgesic effects of a crude extract of Petiveria alliacea L. (Phytolaccaceae)
- in-vivo, NA, NA
TumCMig↓,
6594- Anamu,    Dibenzyl trisulfide induces caspase-independent death and lysosomal membrane permeabilization of triple-negative breast cancer cells
- in-vitro, BC, HCC1806/CRL-2335 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-468
TumCP↓, TumCMig↓, Bak↑, GADD45A↑, LTA/TNF-β↑, lysoMP↑, P450↓, cl‑PARP↑, Dose↝,
6602- Anamu,    Dibenzyl Trisulfide Inhibits the Proliferation and Metastasis of Nsclc Via Suppressing Jak/Stat3 Signal Pathway
- vitro+vivo, NSCLC, H1299 - in-vitro, NSCLC, A549
TumCP↓, TumCMig↓, TumCI↓, Apoptosis↑, BAX↑, Bcl-2↓, EMT↓, p‑STAT3↓, TumCG↓,
1157- And,    Andrographolide suppresses the migratory ability of human glioblastoma multiforme cells by targeting ERK1/2-mediated matrix metalloproteinase-2 expression
- in-vitro, GBM, GBM8401 - in-vitro, GBM, U251
TumCI↓, TumCMig↓, MMP2↓, ERK↝,
1093- And,    Andrographolide attenuates epithelial‐mesenchymal transition induced by TGF‐β1 in alveolar epithelial cells
- in-vitro, Lung, A549
TGF-β↓, TumCMig↓, MMP2↓, MMP9↓, ECM/TCF↓, p‑SMAD2↓, p‑SMAD3↓, SMAD4↓, p‑ERK↓, ROS↓, NOX4↓, SOD2↑, SIRT1↑, FOXO3↑,
6396- ANE,  FEO,    Anethole Inhibits the Proliferation of Human Prostate Cancer Cells via Induction of Cell Cycle Arrest and Apoptosis
- in-vitro, Pca, PC3
TumCP↓, TumCG↓, TumCMig↓, CSCs↓, ROS↑, MPT↑, Casp3↑, Casp9↑, DNAdam↑, cl‑PARP↑, Bax:Bcl2↑, TumCCA↑, cycD1/CCND1↓, CDK4↓, cMyc↓, P21↑, p27/CDKN1B↑, NF-kB↓, eff↑,
7907- Api,  IVT,    Anticancer Potential of Apigenin and Isovitexin with Focus on Oncogenic Metabolism in Cancer Stem Cells
- Review, Var, NA
ChemoSen↑, CSCs↓, Wnt↓, β-catenin/ZEB1↓, PI3K↓, MMP↓, TumMeta↓, MAPK↓, VEGF↓, MMP9↓, TGF-β↓, Inflam↓, COX2/PTGS2↓, IL6↓, NF-kB↓, TumCCA↑, P53↑, cycD1/CCND1↓, BAX↑, Casp↓, Bcl-2↓, CD133↓, Nanog↓, SOX2↓, Akt↓, TumCP↓, TumCMig↓, YAP/TEAD↓, CCN2/CTGF↓, CCN1/CYR61↓, SIRT3↓, SIRT6↓, PCNA↓, DNMT1↓, miR-34a↑,
172- Api,    Apigenin suppresses colorectal cancer cell proliferation, migration and invasion via inhibition of the Wnt/β-catenin signaling pathway
- in-vitro, CRC, SW480 - in-vitro, CRC, HTC15
Wnt/(β-catenin)↓, TCF↓, LEF1↓, TumCP↓, TumCMig↓, TumCI↓,
174- Api,    Downregulation of NEDD9 by apigenin suppresses migration, invasion, and metastasis of colorectal cancer cells
- in-vitro, CRC, SW480 - in-vitro, CRC, DLD1
NEDD9↓, TumCMig↓, TumCI↓,
2632- Api,    Apigenin inhibits migration and induces apoptosis of human endometrial carcinoma Ishikawa cells via PI3K-AKT-GSK-3β pathway and endoplasmic reticulum stress
- in-vitro, EC, NA
TumCP↓, TumCCA↑, Apoptosis↑, Bcl-2↓, BAX↑, Bak↑, Casp↑, ER Stress↑, Ca+2↑, ATF4↑, CHOP/DDIT3↑, ROS↑, MMP↓, TumCMig↓, TumCI↓, eff↑, P53↑, P21↑, Cyt‑c↑, Casp9↑, Casp3↑, Bcl-xL↓,
2641- Api,    Apigenin inhibits HGF-promoted invasive growth and metastasis involving blocking PI3K/Akt pathway and beta 4 integrin function in MDA-MB-231 breast cancer cells
- in-vitro, BC, MDA-MB-231
TumCMig↓, TumCI↓, ITGB4↓,
2593- Api,    Apigenin promotes apoptosis of 4T1 cells through PI3K/AKT/Nrf2 pathway and improves tumor immune microenvironment in vivo
- in-vivo, BC, 4T1
TumCP↓, TumCMig↓, TumCI↓, Apoptosis↑, MMP↑, ROS↑, p‑PI3K↓, PI3K↓, Akt↓, NRF2↓, AntiTum↑, OS↑,
1548- Api,    A comprehensive view on the apigenin impact on colorectal cancer: Focusing on cellular and molecular mechanisms
- Review, Colon, NA
*BioAv↓, *Half-Life∅, selectivity↑, *toxicity↓, Wnt/(β-catenin)↓, P53↑, P21↑, PI3K↓, Akt↓, mTOR↓, TumCCA↑, TumCI↓, TumCMig↓, STAT3↓, PKM2↓, EMT↓, cl‑PARP↑, Casp3↑, Bax:Bcl2↑, VEGF↓, Hif1a↓, Dose∅, GLUT1↓, GlucoseCon↓,
1565- Api,    Apigenin-7-glucoside induces apoptosis and ROS accumulation in lung cancer cells, and inhibits PI3K/Akt/mTOR pathway
- in-vitro, Lung, A549 - in-vitro, Nor, BEAS-2B - in-vitro, Lung, H1975
TumCP↓, Apoptosis↑, TumCMig↓, TumCI↓, Cyt‑c↑, MDA↑, GSH↓, ROS↑, PI3K↓, Akt↓, mTOR↓,
1545- Api,    The Potential Role of Apigenin in Cancer Prevention and Treatment
- Review, NA, NA
TNF-α↓, IL6↓, IL1α↓, P53↑, Bcl-xL↓, Bcl-2↓, BAX↑, Hif1a↓, VEGF↓, TumCCA↑, DNAdam↑, Apoptosis↑, CycB/CCNB1↓, cycA1/CCNA1↓, CDK1↓, PI3K↓, Akt↓, mTOR↓, IKKα↓, ERK↓, p‑Akt↓, p‑P70S6K↓, p‑S6↓, p‑ERK↓, p‑P90RSK↑, STAT3↓, MMP2↓, MMP9↓, TumCP↓, TumCMig↓, TumCI↓, Wnt/(β-catenin)↓,
3396- ART/DHA,    Progress on the study of the anticancer effects of artesunate
- Review, Var, NA
TumCP↓, TumCI↓, TumCMig↓, Apoptosis↑, Diff↑, TumAuto↑, angioG↓, TumCCA↑, ROS↑, AMPK↑, mTOR↑, ChemoSen↑, Tf↑, Ferroptosis↑, Ferritin↓, lipid-P↑, CDK1↑, CDK2↑, CDK4↑, CDK6↑, SIRT1↑, COX2/PTGS2↓, IL1β↓, survivin↓, DNAdam↑, RadioS↑,
574- ART/DHA,    Dihydroartemisinin suppresses glioma proliferation and invasion via inhibition of the ADAM17 pathway
TumCP↓, TumCMig↓, TumCI↓, MMP17↓, p‑EGFR↓, p‑Akt↓,
570- ART/DHA,    Artemisinin and its derivatives can significantly inhibit lung tumorigenesis and tumor metastasis through Wnt/β-catenin signaling
- vitro+vivo, NSCLC, A549 - vitro+vivo, NSCLC, H1299
TumCCA↑, CSCs↓, TumCI↓, TumCMig↓, TumCG↓, Wnt/(β-catenin)↓, Nanog↓, SOX2↓, OCT4↓, N-cadherin↓, Vim↓, E-cadherin↑,
5136- ART/DHA,    Dihydroartemisinin targets VEGFR2 via the NF-κB pathway in endothelial cells to inhibit angiogenesis
- in-vitro, Var, NA
angioG↓, TumCP↓, TumCMig↓, NF-kB↓,
2578- ART/DHA,  RES,    Synergic effects of artemisinin and resveratrol in cancer cells
- in-vitro, Liver, HepG2 - in-vitro, Cerv, HeLa
Dose↝, TumCMig↓, Apoptosis↑, necrosis↑, ROS↑, eff↑,
5415- ASA,    The Anti-Metastatic Role of Aspirin in Cancer: A Systematic Review
- Review, Var, NA
TumMeta↓, COX1↓, TXA2↓, AntiAg↑, EMT↓, TumCMig↓, TumCI↓, AMPK↑, cMyc↓, PGE2↓, Dose↑, RadioS↑, PD-L1↓, E-cadherin↑, EMT↓, Slug↓, Vim↓, Twist↓, MMP2↓, MMP9↓, other↑,
5398- Ash,    Withaferin-A inhibits colorectal cancer growth and metastasis by targeting the HSP90/HIF-1α/EMT axis
- in-vitro, CRC, HCT116 - in-vitro, CRC, SW48
TumCG↓, TumCMig↓, TumCI↓, HSP90↓, Hif1a↓, EMT↓,
3174- Ash,    Withaferin A Acts as a Novel Regulator of Liver X Receptor-α in HCC
- in-vitro, HCC, HepG2 - in-vitro, HCC, Hep3B - in-vitro, HCC, HUH7
NF-kB↓, angioG↓, Inflam↓, TumCP↓, TumCMig↓, TumCI↓, Sp1/3/4↓, VEGF↓, angioG↓, uPA↓, PDGF↓, MCP1/CCL2↓, ICAM-1↓, *NRF2↑, *hepatoP↑,
1362- Ash,  GEM,    Synergistic Inhibition of Pancreatic Cancer Cell Growth and Migration by Gemcitabine and Withaferin A
- in-vitro, PC, PANC1 - in-vitro, PC, Hs766t
ChemoSen↑, ROS↑, Apoptosis↑, TumCMig↓, F-actin↓, YMcells↓, NF-kB↓,
1181- Ash,    Withaferin A inhibits Epithelial to Mesenchymal Transition in Non-Small Cell Lung Cancer Cells
- in-vitro, Lung, A549 - in-vitro, Lung, H1299
TumCMig↓, TumCI↓, EMT↓, p‑SMAD2↓, p‑SMAD3↓, p‑NF-kB↓,
1179- Ash,    Withaferin-A Inhibits Colon Cancer Cell Growth by Blocking STAT3 Transcriptional Activity
- in-vitro, CRC, HCT116 - in-vivo, NA, NA
TumCP↓, TumCMig↓, STAT3↓, TumVol↓, TumW↓,
1173- Ash,    Withaferin A inhibits proliferation of human endometrial cancer cells via transforming growth factor-β (TGF-β) signalling
- in-vitro, EC, K1 - in-vitro, Nor, THESCs
TumCP↓, *toxicity↓, Apoptosis↑, TumCCA↑, TumCMig↓, TumCI↓, p‑SMAD2↓, TGF-β↓, *toxicity↓,
5172- Ash,    Withaferin-A suppress AKT induced tumor growth in colorectal cancer cells
Akt↓, TumCP↓, TumCMig↓, TumCI↓, EMT↓, Snail↓, Slug↓, β-catenin/ZEB1↓, Vim↓, angioG↓,
4811- ASTX,    Astaxanthin reduces MMP expressions, suppresses cancer cell migrations, and triggers apoptotic caspases of in vitro and in vivo models in melanoma
- vitro+vivo, Melanoma, A375 - vitro+vivo, Melanoma, A2058
ROS↓, MMPs↓, TumCMig↓, TumMeta↓, TumCCA↑, antiOx↑, MMP1↓, MMP2↓, MMP9↓,

Showing Research Papers: 1 to 50 of 538
Page 1 of 11 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 538

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

ABCG1↓, 1,   AKR1B10↓, 1,   AKT3↓, 1,   ATG13↑, 2,   ATG16L1↑, 1,   CCN1/CYR61↓, 1,   CD155↓, 1,   CD47↓, 1,   compV↓, 1,   CUL1↝, 1,   CUL5↝, 1,   CX43/GJA1↓, 1,   CXCR3↓, 1,   ERCC3↑, 1,   FGFR4/CD334↓, 1,   GALNT10↓, 1,   HES1↓, 1,   HLA-I/II↑, 1,   HSP60/HSPD1↓, 1,   HTRA↓, 1,   Ingr↝, 1,   IQGAP3↓, 1,   JHDM1D-AS1↓, 1,   LATS1↓, 1,   miR-107↑, 1,   miR-122-5p↑, 1,   miR-124-3p↓, 1,   miR-224↓, 1,   miR-375↑, 1,   miR-422a↑, 1,   miR-542↓, 1,   miR-590-3p↑, 1,   MMP16↓, 1,   MTA1↓, 1,   NA↑, 2,   NA?, 1,   NAT↓, 1,   NFKBIZ/IκBζ↓, 1,   NR3C2/MR↑, 2,   O-Glc↓, 1,   OGFr↑, 2,   PFS↑, 1,   PTN↓, 1,   RUBCN↓, 1,   SBF2-AS1↓, 1,   SERPINH1/HSP47↓, 1,   SGK1↓, 1,   SUV39H↓, 1,   THEM4/CTMP↑, 1,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,   ULK1/ATG1↑, 1,   URGCP/URG4↓, 1,   WDR72↓, 1,   WEE1↑, 1,   XRCC1↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

4-HNE↑, 1,   antiOx↓, 3,   antiOx↑, 5,   ARE↓, 1,   ATF3↑, 2,   Catalase↓, 2,   compI↓, 2,   CYP1A1↓, 2,   CYP1A1↑, 1,   CYP2E1↑, 1,   ENOX2↓, 1,   Ferroptosis↑, 15,   GPx↓, 1,   GPx↑, 1,   GPx1↓, 1,   GPx4↓, 8,   GSH↓, 20,   GSH↑, 3,   i-GSH↓, 1,   GSR↓, 1,   GSTP1/GSTπ↓, 1,   GSTs↑, 1,   H2O2↓, 2,   H2O2↑, 4,   HK1↓, 2,   HO-1↓, 6,   HO-1↑, 5,   Iron↑, 4,   i-Iron↑, 1,   Keap1↓, 1,   lipid-P↓, 4,   lipid-P↑, 6,   lipid-P↝, 1,   MDA↓, 1,   MDA↑, 6,   i-MDA↑, 1,   NADH↓, 1,   NOX4↓, 1,   NRF2↓, 14,   NRF2↑, 9,   p‑NRF2↑, 1,   OXPHOS↓, 3,   OXPHOS↑, 2,   p66Shc↓, 1,   PARK2↑, 2,   ROS?, 1,   ROS↓, 27,   ROS↑, 147,   ROS⇅, 1,   ROS↝, 3,   ROS∅, 1,   i-ROS↑, 1,   mt-ROS↑, 3,   SIRT3↓, 1,   SIRT3↑, 1,   SOD↓, 6,   SOD1↓, 1,   SOD2↓, 3,   SOD2↑, 1,   TAC↓, 2,   Trx↓, 2,   ox-Trx1↑, 1,   TrxR↓, 3,   TrxR1↓, 3,   VDAC1↓, 1,   xCT/SLC7A11↓, 3,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   Ferritin↑, 1,   FTH1↓, 2,   IronCh↑, 1,   NCOA4↑, 1,   STEAP3↓, 1,   Tf↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ABL1↓, 1,   AIF↑, 4,   ATP↓, 16,   i-ATP↓, 1,   CDC2↓, 3,   CDC25↓, 3,   compIII↓, 1,   EGF↓, 4,   ETC↓, 3,   FGFR1↓, 2,   MEK↓, 4,   p‑MEK↓, 3,   mitResp↑, 1,   MMP↓, 61,   MMP↑, 1,   MMP↝, 1,   MMP∅, 1,   MPT↑, 4,   mtDam↑, 15,   OCR↓, 7,   OCR↑, 1,   PGC-1α↑, 1,   PINK1↑, 2,   Raf↓, 4,   c-Raf↓, 1,   XIAP↓, 13,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 2,   Ac-histone H3↑, 1,   ACC↓, 2,   ACLY↓, 1,   ACSL4↑, 1,   AKT1↓, 3,   ALAT↓, 3,   ALDOA↓, 1,   AMPK↓, 1,   AMPK↑, 16,   AMPK↝, 1,   p‑AMPK↑, 6,   ATG7↑, 2,   Cav1↓, 1,   cMyc↓, 25,   CREB↓, 1,   CYP3A4↓, 1,   ECAR↓, 6,   ENO1↓, 1,   FASN↓, 5,   FDG↓, 1,   G6PD↓, 1,   GlucoseCon↓, 10,   Glycolysis↓, 27,   Glycolysis↑, 1,   Histones↑, 1,   ac‑Histones↑, 1,   HK2↓, 12,   HMG-CoA↓, 1,   IDH1↑, 1,   IR↓, 2,   lactateProd↓, 13,   LDH↓, 3,   LDH↑, 1,   LDHA↓, 9,   LDHA∅, 1,   LDL↓, 1,   lipidLev↓, 1,   lipoGen↓, 2,   NADPH↓, 1,   PDH↑, 2,   PDH∅, 1,   PDHB↓, 1,   PDK1 / PDPK1↓, 7,   p‑PDK1 / PDPK1↓, 1,   PFK↓, 3,   PFKFB2↓, 1,   PGK1↓, 2,   PGM1↓, 1,   PI3K/Akt↓, 5,   PI3k/Akt/mTOR↓, 1,   PKM2↓, 18,   PKM2∅, 1,   PPARα↝, 1,   PPARγ↑, 2,   Pyruv↓, 1,   RARα↓, 1,   RARβ↑, 1,   RARγ↑, 1,   p‑S6↓, 1,   p‑S6K↓, 1,   SCD1↓, 1,   SIRT1↓, 6,   SIRT1↑, 3,   SREBP1/SREBF1↓, 5,   TCA↓, 1,   TumCM/A↑, 1,   Warburg↓, 2,  

Cell Death(tgid=5) ⓘ

AhR↑, 1,   Akt↓, 104,   Akt↑, 1,   p‑Akt↓, 44,   APAF1↑, 5,   Apoptosis↓, 9,   Apoptosis↑, 229,   mt-Apoptosis↑, 2,   ATF2↓, 2,   BAD↓, 1,   BAD↑, 6,   Bak↑, 5,   BAX↓, 1,   BAX↑, 80,   BAX⇅, 1,   Bax:Bcl2↑, 18,   Bcl-2↓, 94,   Bcl-xL↓, 10,   BID↑, 1,   BIM↑, 1,   Casp↓, 2,   Casp↑, 15,   Casp↝, 1,   cl‑Casp↑, 1,   Casp1↓, 1,   Casp1↑, 2,   cl‑Casp1↑, 1,   Casp10∅, 1,   Casp12↑, 2,   cl‑Casp12↑, 1,   Casp2↑, 2,   Casp3↓, 1,   Casp3↑, 78,   cl‑Casp3↑, 29,   Casp7↑, 9,   cl‑Casp7↑, 1,   Casp8↑, 17,   Casp8∅, 1,   cl‑Casp8↑, 4,   proCasp8↑, 1,   Casp9↑, 39,   cl‑Casp9↑, 11,   CBP↓, 1,   cFLIP↓, 4,   Chk2↑, 2,   CK2↓, 3,   Cyt‑c↓, 2,   Cyt‑c↑, 31,   DR4↑, 3,   DR4∅, 1,   DR5↑, 8,   DR5∅, 1,   Endon↑, 1,   FADD↑, 1,   FADD∅, 1,   Fas↓, 2,   Fas↑, 9,   FasL↓, 1,   FasL↑, 1,   Ferroptosis↑, 15,   GRP58↓, 1,   GSDMD↑, 2,   hTERT/TERT↓, 3,   IAP1↓, 3,   IAP2/BIRC3↓, 2,   iNOS↓, 7,   JNK↓, 3,   JNK↑, 9,   p‑JNK↓, 1,   p‑JNK↑, 1,   p‑JNK↝, 1,   lysoMP↑, 2,   MAPK↓, 17,   MAPK↑, 7,   p‑MAPK↓, 1,   p‑MAPK↑, 1,   Mcl-1↓, 6,   Mcl-1↑, 1,   MDM2↓, 5,   MDM2↑, 1,   MOMP↓, 2,   MOMP↑, 2,   Myc↓, 2,   Myc↑, 1,   Necroptosis↑, 2,   necrosis↑, 3,   NOXA↑, 3,   p27/CDKN1B↓, 1,   p27/CDKN1B↑, 12,   p38↓, 4,   p38↑, 9,   p‑p38↓, 3,   p‑p38↑, 4,   p‑p38↝, 1,   Proteasome↓, 1,   PUMA↑, 4,   Pyro↑, 2,   RIP1↓, 2,   survivin↓, 24,   Telomerase↓, 5,   TRAIL⇅, 1,   TRAILR↑, 1,   TRPV1↑, 3,   TumCD?, 1,   TumCD↓, 1,   TumCD↑, 11,   TumCD∅, 1,   YAP/TEAD↓, 5,   β-TRCP↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

AMPKα↓, 1,   p‑CaMKII ↓, 1,   EF-1α↓, 1,   FOXD3↑, 1,   HER2/EBBR2↓, 5,   miR-25-5p↓, 1,   p‑p70S6↓, 1,   Sp1/3/4↓, 13,   TSC2↑, 2,   p‑TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ChrMod↝, 1,   cJun↓, 5,   cJun↑, 1,   EZH2↓, 2,   H3↓, 1,   H3↑, 1,   ac‑H3↓, 1,   H4↑, 1,   ac‑H4↓, 1,   HATs↓, 2,   HATs↑, 3,   Matr↓, 1,   miR-143↑, 1,   miR-145↑, 1,   miR-192-5p↑, 1,   miR-205↑, 1,   miR-21↓, 4,   miR-30a-5p↑, 1,   other↓, 2,   other↑, 2,   other↝, 8,   p‑pRB↓, 1,   TLE1↓, 1,   tumCV↓, 81,   YMcells↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 12,   cl‑CHOP/DDIT3↑, 1,   eIF2α↓, 1,   eIF2α↑, 5,   p‑eIF2α↑, 1,   ER Stress↑, 20,   GRP78/BiP?, 1,   GRP78/BiP↓, 2,   GRP78/BiP↑, 7,   HSP70/HSPA5↓, 2,   HSP70/HSPA5↑, 1,   HSP90↓, 9,   IRE1↑, 1,   PERK↑, 7,   p‑PERK↑, 1,   UPR↑, 3,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG3↑, 1,   ATG5↑, 2,   Beclin-1/ATG6↓, 4,   Beclin-1/ATG6↑, 3,   BNIP3↑, 2,   LAMP2↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 3,   LC3B↓, 1,   LC3B-II↓, 1,   LC3B-II↑, 1,   LC3I↑, 1,   LC3II↓, 2,   LC3II↑, 4,   LC3s↓, 1,   p62↓, 2,   p62↑, 3,   p‑p62↑, 1,   SESN2↑, 1,   TumAuto↑, 31,   TumAuto⇅, 1,   TumAuto↝, 1,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 2,   ATR↑, 2,   BRCA1↓, 2,   BRCA1↑, 2,   BRCA2↑, 1,   CHK1↓, 1,   CHK1↑, 2,   p‑CHK1↑, 1,   CYP1B1↓, 1,   DNA-PK↑, 1,   DNAdam↓, 1,   DNAdam↑, 34,   DNArepair↓, 2,   DNMT1↓, 4,   DNMT1↑, 1,   DNMTs↓, 1,   GADD45A↑, 3,   MGMT↓, 1,   NKX3.1↑, 1,   P53?, 1,   P53↓, 1,   P53↑, 52,   P53↝, 2,   P53∅, 1,   p‑P53↑, 3,   ac‑P53↑, 1,   i-P53↓, 1,   p73↑, 1,   PARP↓, 3,   PARP↑, 6,   p‑PARP↑, 2,   cl‑PARP↓, 1,   cl‑PARP↑, 36,   cl‑PARP1↑, 2,   PCLAF↓, 1,   PCNA↓, 17,   PCNA↑, 1,   RAD51↓, 1,   SIRT6↓, 1,   TP53↑, 1,   γH2AX↑, 7,   γH2AX↝, 1,   p‑γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 6,   CDK1↑, 1,   p‑CDK1↓, 1,   CDK2↓, 18,   CDK2↑, 2,   CDK4↓, 25,   CDK4↑, 3,   CDK4∅, 1,   Cyc↓, 2,   cycA1/CCNA1↓, 8,   cycA1/CCNA1↑, 1,   CycB/CCNB1↓, 13,   cycD1/CCND1↓, 50,   cycD1/CCND1↑, 2,   cycD1/CCND1∅, 1,   CycD3↓, 1,   cycE/CCNE↓, 14,   E2Fs↓, 1,   P21?, 1,   P21↓, 2,   P21↑, 33,   RB1↑, 2,   p‑RB1↓, 2,   Securin↓, 1,   TFAP2A↓, 1,   TumCCA?, 1,   TumCCA↓, 6,   TumCCA↑, 141,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

4E-BP1↓, 2,   p‑4E-BP1↓, 2,   ALDH↓, 6,   ALDH1A1↓, 1,   AXIN1↑, 1,   BMI1↓, 2,   CD133↓, 10,   CD24↓, 3,   CD44↓, 11,   cFos↓, 5,   cMET↓, 1,   p‑cMET↑, 2,   CSCs↓, 31,   CTNNB1↓, 1,   CTSB↓, 1,   CTSD↓, 1,   Diff↓, 1,   Diff↑, 2,   EMT↓, 114,   EpCAM↓, 2,   ERK↓, 34,   ERK↑, 5,   ERK↝, 1,   p‑ERK↓, 21,   p‑ERK⇅, 1,   p‑ERK↝, 1,   ERK5↑, 1,   FGF↓, 3,   FGF↑, 1,   FGFR2↓, 1,   FOXM1↓, 5,   FOXO↑, 1,   FOXO1↓, 1,   FOXO3↓, 1,   FOXO3↑, 4,   Gli↓, 1,   Gli1↓, 9,   GREM1↓, 1,   GSK‐3β↓, 6,   GSK‐3β↑, 1,   GSK‐3β↝, 1,   p‑GSK‐3β↓, 1,   HDAC↓, 11,   HDAC1↓, 5,   HDAC2↓, 1,   HDAC3↓, 2,   HDAC4↓, 1,   HDAC6↓, 2,   HDAC8↓, 1,   HH↓, 7,   HRAS↓, 1,   IGF-1↓, 4,   IGFBP3↑, 2,   IGFR↓, 1,   p‑IGFR↓, 1,   Jun↓, 1,   Let-7↑, 1,   LRP6↓, 4,   p‑LRP6↓, 2,   p‑MAP2K1/MEK1↓, 1,   MCM2↓, 1,   miR-34a↑, 5,   miR-99↑, 1,   MSCmark↓, 1,   Mst1↑, 1,   mTOR↓, 46,   mTOR↑, 3,   mTOR↝, 1,   p‑mTOR↓, 16,   mTORC1↓, 3,   mTORC2↓, 2,   mTORC2↑, 1,   Nanog↓, 8,   Nestin↓, 3,   NOTCH↓, 7,   NOTCH1↓, 6,   NOTCH1↝, 1,   NOTCH3↓, 2,   NRAS↓, 1,   OCT4↓, 8,   p300↓, 2,   P70S6K↓, 5,   p‑P70S6K↓, 1,   p‑P90RSK↑, 1,   PI3K↓, 71,   PI3K↑, 1,   p‑PI3K↓, 13,   PTCH1↓, 3,   PTCH2↓, 1,   PTEN↑, 11,   RAS↓, 6,   RAS↑, 1,   Shh↓, 5,   Smo↓, 5,   SOX2↓, 8,   Src↓, 4,   STAT↓, 2,   p‑STAT↓, 1,   STAT3↓, 46,   STAT3↑, 2,   p‑STAT3↓, 10,   p‑STAT3↑, 3,   i-STAT3↓, 1,   STAT5↓, 1,   STAT6↓, 1,   Sufu↓, 1,   TAZ↓, 2,   TCF↓, 1,   TCF-4↓, 1,   TOP1↓, 3,   TOP2↓, 1,   TOP2↑, 1,   TOPflash↓, 1,   TRPM7↓, 2,   TumCG?, 1,   TumCG↓, 98,   TumCG↑, 4,   tyrosinase↓, 2,   Wnt↓, 26,   Wnt/(β-catenin)↓, 6,   ZFX↓, 1,  

Migration(tgid=13) ⓘ

5LO↓, 1,   AntiAg↑, 2,   AP-1↓, 2,   AP-1↝, 1,   CA↓, 1,   Ca+2↑, 22,   i-Ca+2↓, 1,   i-Ca+2↑, 1,   cal2↑, 1,   CCAT1↓, 1,   CCN2/CTGF↓, 2,   CD31/PECAM-1↓, 3,   CDK4/6↓, 1,   CDKN1C/p57↑, 1,   CLDN1↓, 2,   CLDN2↓, 1,   p‑Cofilin↑, 2,   COL1A1↓, 1,   COL3A1↓, 1,   CXCL12↓, 1,   E-cadherin↓, 6,   E-cadherin↑, 67,   EM↑, 1,   ER-α36↓, 2,   F-actin↓, 4,   FAK↓, 16,   p‑FAK↓, 4,   Fibronectin↓, 2,   FTO↓, 1,   FTO↑, 1,   Galectin-9↓, 1,   GLI2↓, 2,   ITGB1↓, 4,   ITGB4↓, 1,   ITGB6↓, 1,   Ki-67↓, 19,   KRAS↓, 2,   LEF1↓, 2,   LRP1↓, 1,   MALAT1↓, 1,   MET↓, 2,   MET↑, 2,   p‑MET↓, 1,   miR-130a↓, 2,   miR-139-5p↑, 2,   miR-148a↓, 1,   miR-155↓, 1,   miR-19b↓, 1,   miR-203↑, 1,   miR-206↑, 1,   miR-340↓, 1,   miR-384↑, 1,   MMP-10↓, 1,   MMP1↓, 5,   MMP13↓, 3,   MMP14↓, 1,   MMP17↓, 1,   MMP2?, 1,   MMP2↓, 93,   MMP2↝, 1,   MMP3↓, 7,   MMP7↓, 8,   MMP9?, 1,   MMP9↓, 99,   MMP9↝, 1,   MMPs↓, 25,   N-cadherin?, 1,   N-cadherin↓, 42,   N-cadherin↑, 1,   NCAM↓, 1,   NEDD9↓, 4,   PAI-1/SERPINE1↓, 1,   PAK1↓, 1,   pax↓, 1,   p‑pax↓, 1,   PDGF↓, 3,   PKA↓, 3,   PKCδ↓, 5,   PKCδ↑, 1,   PTK2B / PYK2↓, 1,   Rac1↓, 2,   RHBDD1↓, 1,   Rho↓, 4,   Rho↑, 1,   RIP3↓, 1,   ROCK1↓, 1,   ROCK1↑, 1,   Slug↓, 19,   Smad1↓, 3,   Smad1↑, 1,   SMAD2↓, 3,   p‑SMAD2↓, 12,   SMAD3↓, 7,   p‑SMAD3↓, 10,   SMAD4↓, 2,   SMAD4↑, 1,   Snail↓, 32,   SOX4↓, 1,   T-cadherin↑, 1,   TET1↑, 2,   TGF-β↓, 19,   TGF-β↑, 1,   TGF-β1↓, 4,   THBS1↓, 1,   TIMP1↓, 3,   TIMP1↑, 9,   TIMP2↓, 3,   TIMP2↑, 7,   TIMP3↑, 2,   Treg lymp↓, 1,   TRIB3↑, 1,   TSC1↑, 1,   TSP-1↑, 2,   TumCA↓, 11,   TumCA↑, 1,   TumCI?, 1,   TumCI↓, 310,   TumCMig↓, 543,   TumCP?, 2,   TumCP↓, 251,   TumMeta↓, 55,   TumMeta↑, 1,   Twist↓, 15,   TXNIP↑, 1,   uPA↓, 13,   uPAR↓, 2,   VCAM-1↓, 2,   VEGFR1↓, 1,   Vim↓, 48,   Vim↑, 1,   vinculin↓, 1,   Zeb1↓, 15,   Zeb1↑, 1,   ZEB2↓, 3,   ZO-1↓, 1,   ZO-1↑, 5,   α-SMA↓, 3,   α-SMA↑, 1,   α-tubulin↓, 1,   α-tubulin↑, 2,   ac‑α-tubulin↑, 1,   β-catenin/ZEB1↓, 49,   β-catenin/ZEB1↑, 3,   cl‑β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 71,   angioG↑, 1,   ATF4↑, 5,   ECM/TCF↓, 1,   EGFR↓, 24,   p‑EGFR↓, 2,   EGR1↓, 1,   EGR4↓, 1,   EPR↑, 2,   HIF-1↓, 5,   Hif1a↓, 43,   Hif1a↑, 2,   Hif1a↝, 1,   LOX1↓, 1,   NO↓, 2,   TAMS↓, 2,   TXA2↓, 1,   VEGF↓, 62,   VEGF↑, 1,   VEGFR2/KDR/Flk1↓, 8,  

Barriers & Transport(tgid=15) ⓘ

AQPs↓, 3,   BBB↑, 2,   GLUT1↓, 7,   GLUT1∅, 1,   GLUT3↓, 1,   GLUT3∅, 1,   NHE1↓, 1,   P-gp/ABCB1↓, 8,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

ASC↑, 1,   B2M↓, 1,   CD25+↓, 1,   CD25+↑, 1,   CD4+↓, 1,   CD4+↑, 2,   COX1↓, 1,   COX2/PTGS2↓, 33,   COX2/PTGS2↑, 1,   COX2/PTGS2↝, 1,   CXCc↓, 1,   CXCR4↓, 9,   FOXP3↑, 1,   FoxP3+↓, 1,   HMGB1↓, 3,   ICAM-1↓, 5,   IFN-γ↓, 1,   IFN-γ↑, 1,   IKKα↓, 5,   IKKα↑, 1,   IKKα↝, 1,   p‑IKKα↓, 1,   IL1↓, 3,   IL10↓, 1,   IL17↓, 1,   IL18↓, 4,   IL1α↓, 1,   IL1β↓, 10,   IL2↓, 2,   IL4↓, 1,   IL6↓, 16,   IL6↑, 1,   IL8↓, 4,   Imm↑, 7,   Imm↝, 1,   Inflam↓, 23,   Inflam↝, 1,   IRAK4↓, 1,   p‑IκB↓, 1,   p‑IκB↑, 1,   JAK↓, 4,   JAK↝, 1,   JAK2↓, 8,   p‑JAK2↓, 1,   LIF↑, 1,   LTA/TNF-β↑, 1,   M2 MC↓, 1,   MCP1/CCL2↓, 1,   NF-kB↓, 92,   NF-kB↑, 4,   NF-kB↝, 1,   p‑NF-kB↓, 3,   p‑NF-kB↑, 1,   NK cell↑, 1,   p65↓, 7,   p‑p65↓, 1,   PD-1↓, 2,   PD-L1↓, 8,   PD-L1↑, 3,   PD-L2↓, 1,   PGE2↓, 11,   PSA↓, 6,   T-Cell↑, 2,   TILs↑, 1,   TLR2↓, 1,   TLR4↓, 6,   TNF-α↓, 17,   TNF-α↑, 3,  

Cellular Microenvironment(tgid=17) ⓘ

pH↑, 1,   TIM-3↓, 1,  

Protein Aggregation(tgid=19) ⓘ

NLRP3↓, 7,   NLRP3↑, 1,   PP2A↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 7,   AR↑, 1,   CDK6↓, 8,   CDK6↑, 3,   CDK6∅, 1,   ERβ/ESR2↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 3,   BioAv↓, 17,   BioAv↑, 21,   BioAv↝, 4,   BioEnh?, 1,   BioEnh↑, 1,   ChemoSen↓, 1,   ChemoSen↑, 84,   CYP1A2↑, 1,   CYP2A3/CYP2A6↓, 1,   Dose?, 2,   Dose↓, 5,   Dose↑, 2,   Dose↝, 37,   Dose∅, 5,   eff↓, 22,   eff↑, 83,   eff↝, 6,   Half-Life↓, 4,   Half-Life↑, 1,   Half-Life↝, 5,   P450↓, 2,   RadioS↑, 24,   selectivity?, 1,   selectivity↑, 69,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 1,   ALAT↓, 3,   ALP↓, 1,   AR↓, 7,   AR↑, 1,   AST↓, 3,   B2M↓, 1,   BMD↑, 1,   BMPs↑, 2,   BRCA1↓, 2,   BRCA1↑, 2,   EGFR↓, 24,   p‑EGFR↓, 2,   EZH2↓, 2,   Ferritin↓, 1,   Ferritin↑, 1,   FOXM1↓, 5,   GutMicro↑, 3,   HER2/EBBR2↓, 5,   hTERT/TERT↓, 3,   IL6↓, 16,   IL6↑, 1,   Ki-67↓, 19,   KRAS↓, 2,   LDH↓, 3,   LDH↑, 1,   Maspin↑, 1,   Myc↓, 2,   Myc↑, 1,   PD-L1↓, 8,   PD-L1↑, 3,   PSA↓, 6,   TP53↑, 1,   TRIB3↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↓, 2,   AntiCan↑, 35,   AntiCan∅, 1,   AntiDiabetic↑, 2,   antiNeop↑, 2,   AntiTum↓, 1,   AntiTum↑, 22,   cardioP↑, 3,   CardioT↓, 1,   chemoP↓, 1,   chemoP↑, 18,   chemoPv↑, 11,   ChemoSideEff↓, 1,   hepatoP↑, 4,   NDRG1↑, 1,   neuroP↑, 3,   NP/CIPN↓, 1,   Obesity↓, 1,   OS↑, 13,   Pin1↓, 1,   PRAS40↓, 1,   PRAS40↑, 1,   QoL↑, 2,   radioP↑, 5,   RenoP↑, 2,   Risk↓, 9,   toxicity?, 1,   toxicity↓, 11,   toxicity↑, 2,   toxicity↝, 2,   toxicity∅, 2,   TumVol↓, 30,   TumVol↑, 1,   TumW↓, 12,   Weight∅, 2,   Wound Healing↓, 3,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

CD8+↑, 5,   Sepsis↓, 1,  
Total Targets: 945

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 5,   compII↑, 1,   diuretic↑, 1,   Ingr↝, 1,   Stroke↓, 2,   TPH1↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 4,   antiOx↑, 54,   Bil↓, 1,   Catalase↑, 15,   GPx↑, 14,   GPx1↑, 2,   GSH↑, 14,   GSR↑, 2,   GSTs↑, 6,   H2O2↓, 1,   HDL↓, 1,   HDL↑, 3,   HO-1↓, 1,   HO-1↑, 6,   Keap1↓, 2,   Keap1↑, 1,   lipid-P↓, 15,   MDA↓, 8,   MPO↓, 4,   NADH↓, 1,   NQO1↑, 1,   NRF2↑, 16,   RNS↓, 2,   ROS?, 1,   ROS↓, 38,   ROS↑, 1,   SAM-e↑, 1,   SIRT3↑, 1,   SOD↑, 15,   SOD1↑, 4,   SOD2↑, 1,   TAC↑, 2,   TBARS↓, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↑, 1,   ATP↝, 1,   compIII↑, 1,   MMP↑, 1,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 6,   BUN↓, 1,   glucose↓, 3,   glucose↑, 1,   glucose↝, 2,   GlucoseCon↑, 1,   GLUT2↑, 1,   H2S↑, 1,   HMG-CoA↓, 1,   LDH↓, 5,   LDL↓, 5,   NAD↑, 1,   NAD↝, 1,   NADPH↓, 1,   PPARγ↓, 1,   PPARγ↑, 2,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 1,   Akt↑, 1,   Casp1↓, 1,   Casp12↓, 1,   Casp3↓, 3,   Casp9↓, 1,   Fas↓, 2,   GranB/GZMB↓, 1,   HGF/c-Met↑, 1,   iNOS↓, 9,   JNK↑, 1,   p‑JNK↓, 1,   MAPK↓, 4,   p38↓, 1,   survivin↓, 1,   Telomerase↓, 1,   TRPV1↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ach↑, 1,   AntiThr↑, 2,   other↓, 2,   other↑, 3,   other↝, 4,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 1,   p‑eIF2α↓, 1,   ER Stress↓, 1,   GRP78/BiP↓, 1,   GRP78/BiP↑, 1,   GRP94↑, 1,   HSP70/HSPA5↓, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

LC3‑Ⅱ/LC3‑Ⅰ↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Diff↝, 1,   ERK↓, 2,   p‑ERK↑, 1,   GSK‐3β↓, 1,   mTOR↓, 2,   PI3K↓, 1,   PI3K↑, 1,   PTEN↑, 1,   STAT3↓, 1,   VGSC↓, 1,  

Migration(tgid=13) ⓘ

5LO↓, 2,   AntiAg↑, 4,   APP↓, 1,   Ca+2↑, 1,   Ca+2↝, 1,   CEA↓, 1,   MMP9↓, 1,   PAI-1/SERPINE1↓, 1,   p‑Rac1↓, 1,   Rho↓, 1,   serineP↓, 1,   TGF-β↑, 1,   TIMP1↓, 1,   TumCI∅, 1,   TumCMig∅, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   ATF4↓, 1,   NO↓, 4,   VEGF↓, 1,   VEGF↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 4,   GastroP↑, 2,   IBI↑, 2,   P-gp/ABCB1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   COX1↓, 1,   COX2/PTGS2↓, 12,   IFN-γ↓, 4,   IKKα↑, 1,   IL1↓, 1,   IL10↓, 2,   IL10↑, 1,   IL12↓, 1,   IL17↓, 1,   IL1β↓, 9,   IL23↓, 1,   IL4↓, 1,   IL6↓, 13,   IL8↓, 1,   Imm↑, 5,   Inflam?, 1,   Inflam↓, 54,   Inflam↑, 2,   LPS↓, 1,   MCP1/CCL2↓, 1,   MyD88↓, 1,   NF-kB↓, 15,   PGE2↓, 3,   TLR2↓, 2,   TLR4↓, 5,   TNF-α↓, 14,   VitD↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   AChE↓, 5,   AChE↑, 1,   BChE↓, 1,   BDNF↑, 2,   ChAT↑, 1,   GABA↑, 1,   MAOA↓, 1,   p‑tau↓, 2,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 2,   Aβ↓, 8,   BACE/β-secretase↓, 2,   NLRP3↓, 4,   XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

testos↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 12,   BioAv↑, 23,   BioAv⇅, 1,   BioAv↝, 13,   Dose↑, 1,   Dose↝, 6,   eff↑, 10,   Half-Life↓, 2,   Half-Life↝, 4,   Half-Life∅, 1,   P450↓, 2,   selectivity↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 6,   ALP↓, 3,   AST↓, 6,   Bil↓, 1,   BMD↑, 1,   BMPs↑, 1,   BP↓, 4,   Calcium↑, 1,   CEA↓, 1,   creat↓, 2,   GutMicro↑, 9,   hs-CRP↓, 1,   IL6↓, 13,   LDH↓, 5,   Mag↑, 1,   NOS2↓, 1,   Urea↓, 1,   VitD↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiArt↑, 5,   AntiCan↓, 1,   AntiCan↑, 9,   antiD↓, 1,   AntiDiabetic↑, 13,   AntiP↑, 1,   antiPs↑, 1,   AntiTum↑, 1,   cardioP↑, 20,   chemoP↑, 2,   chemoPv↑, 3,   ChemoSideEff↓, 1,   cognitive↓, 1,   cognitive↑, 5,   hepatoP↑, 19,   memory↑, 9,   neuroP?, 1,   neuroP↑, 36,   Obesity↓, 5,   OS↑, 1,   Pain↓, 1,   QoL↑, 1,   radioP↑, 1,   RenoP↑, 5,   Risk↓, 1,   toxicity↓, 18,   toxicity↑, 1,   toxicity↝, 6,   toxicity∅, 8,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 1,   AntiViral↑, 4,   Bacteria↓, 16,   IRF3↓, 1,   Sepsis↓, 2,  
Total Targets: 237

Scientific Paper Hit Count for: TumCMig, Tumor cell migration
21 Curcumin
15 Quercetin
13 Honokiol
13 Shikonin
11 Berberine
11 Luteolin
10 Fisetin
9 Apigenin (mainly Parsley)
9 Resveratrol
9 EGCG (Epigallocatechin Gallate)
9 Dandelion Root
9 Magnetic Fields
9 Silymarin (Milk Thistle) silibinin
8 Betulinic acid
8 Capsaicin
8 Magnolol
8 Sulforaphane (mainly Broccoli)
7 Ashwagandha(Withaferin A)
7 Thymoquinone
7 Kaempferol
7 Licochalcone A
7 Urolithin
6 Propolis -bee glue
6 Chlorogenic acid
6 Metformin
6 Piperlongumine
6 Rosmarinic acid
5 Silver-NanoParticles
5 Alpha-Lipoic-Acid
5 Artemisinin
5 Baicalein
5 Radiotherapy/Radiation
5 Carvacrol
5 Emodin
5 Eugenol
5 Ferulic acid
5 Ginkgetin
5 Hyperoside
5 Licorice
5 Phenethyl isothiocyanate
5 Piperine
4 Astragalus
4 Gemcitabine (Gemzar)
4 Astaxanthin
4 Boron
4 5-fluorouracil
4 Gallic acid
4 Ginkgolide B
4 Indole-3-carbinol
4 Isoliquiritigenin
4 Ivermectin
4 Juglone
4 Nimbolide
4 Pterostilbene
3 DTS(dibenzyl trisulphide) from Anamu
3 Berbamine
3 Bacopa monnieri
3 brusatol
3 Caffeic acid
3 Paclitaxel/Taxol
3 Chrysin
3 Cinnamon
3 Crocetin
3 Cucurbitacin
3 CUSP9
3 Deguelin
3 Evodiamine
3 Formononetin
3 Fucoidan
3 Garcinol
3 Hibiscus sabdariffa
3 HydroxyTyrosol
3 Cisplatin
3 Linalool
3 Lycopene
3 Marjoram (Origanum majorana)
3 salinomycin
3 Aflavin-3,3′-digallate
2 1,8-Cineole
2 Allicin (mainly Garlic)
2 Andrographis
2 Fennel Oil/Foeniculum vulgare
2 Isovitexin
2 Aspirin
2 Arctigenin
2 Beta-Caryophyllene
2 Bufalin/Huachansu
2 Genistein (soy isoflavone)
2 Boswellia (frankincense)
2 Carnosic acid
2 Celecoxib
2 Celastrol
2 Centella asiatica / Gotu kola → asiaticoside
2 chaetocin
2 Chlorophyllin
2 Docetaxel
2 Carvone
2 Disulfiram
2 Copper and Cu NanoParticles
2 Ellagic acid
2 Ginkgolic acids
2 Ginkgo biloba
2 Geraniol
2 Grapeseed extract
2 Hydrogen Gas
2 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
2 isoflavones
2 isoorientin
2 isoquercitrin
2 doxorubicin
2 Plumbagin
2 low dose naltrexone
2 Lutein
2 Magnetic Field Rotating
2 Psoralidin
2 Parthenolide
2 α-Santalol/Sandalwood oil
2 Ursolic acid
2 Vitamin C (Ascorbic Acid)
2 VitK3,menadione
1 3-bromopyruvate
1 Auranofin
1 Ajoene (compound of Garlic)
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Anethole/trans-Anethole
1 Atorvastatin
1 Aloe anthraquinones
1 Baicalin
1 Biochanin A
1 Bevacizumab (brand Avastin)
1 Brucea javanica
1 Bromelain
1 selenomethionine
1 Bruteridin(bergamot juice)
1 α-Bisabolol / Chamomile oil
1 Butyrate
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Cannabidiol
1 chitosan
1 Selenium NanoParticles
1 Hydroxycinnamic-acid
1 Citric Acid
1 Oxaliplatin
1 Electrical Pulses
1 Cynaropicrin
1 Cysteamine
1 Dichloroacetophenone(2,2-)
1 Dasatinib/Phyrago
1 Diclofenac
1 Date Fruit Extract
1 Docosahexaenoic Acid
1 diet Short Term Fasting
1 D-limonene
1 Mistletoe/Viscum album Extracts
1 Ginkgo biloba-EGb 761
1 Tetrahydroxystilbene glucoside
1 eicosapentaenoic acid
1 erastin
1 Eurycomanone
1 Shilajit/Fulvic Acid
1 olaparib/LYNPARZA
1 Galloflavin
1 Gambogic Acid
1 Ginger/6-Shogaol/Gingerol
1 Ginseng
1 γ-linolenic acid (Borage Oil)
1 Gossypol/AT-101
1 Graviola
1 Proanthocyanidins
1 HydroxyCitric Acid
1 Hops (Humulus lupulus)
1 Isobavachalcone
1 itraconazole
1 Lapachol
1 Lasiodin
1 Lactoferrin/Talactoferrin
1 SDG/lignans
1 Melatonin
1 Methyl salicylate / Sweet Birch oil
1 immunotherapy
1 Myricetin
1 Naringin
1 Niclosamide (Niclocide)
1 Oroxylin A
1 Orlistat
1 Propyl gallate
1 temozolomide
1 raloxifen
1 tamoxifen
1 Germacranolide sesquiterpene lactone
1 Rauwolfia serpentina/Indian Snakeroot
1 Sanguinarine
1 Sulfasalazine
1 Selenite (Sodium)
1 Terpinen-4-ol / Tea Tree Oil
1 Thymol-Thymus vulgaris
1 Usnic acid
1 Arsenic trioxide
1 Vitexin
1 β‐Elemene
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:326  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

Home Page