DHT Cancer Research Results

DHT, dihydrotestosterone level: Click to Expand ⟱
Source:
Type: male hormone
DHT (dihydrotestosterone) is a type of androgen, a male sex hormone, that stimulates the development of masculine characteristics such as body hair, muscle growth, and a deep voice. People who have prostate cancer usually have an increase in DHT levels.
Scientific Papers found: Click to Expand⟱
131- CUR,    Modulation of AKR1C2 by curcumin decreases testosterone production in prostate cancer
- vitro+vivo, Pca, LNCaP - vitro+vivo, Pca, 22Rv1
AKR1C2↓, CYP11A1↓, HSD3B↓, DHT↓, testos↓, StAR↓, SRD5A1↑, AR↓, tumCV↓, TumCG↓, Apoptosis↑,
8300- FS,    Flaxseed supplementation (not dietary fat restriction) reduces prostate cancer proliferation rates in men presurgery
- Trial, Pca, NA
Dose↝, TumCP↓, Ki-67↓, *toxicity↓, Ingr↑, testos↓, DHT↓, Risk↓, Dose↝,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

Ingr↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

tumCV↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

TumCG↓, 1,  

Migration(tgid=13) ⓘ

AKR1C2↓, 1,   Ki-67↓, 1,   TumCP↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 1,   CYP11A1↓, 1,   DHT↓, 2,   HSD3B↓, 1,   SRD5A1↑, 1,   StAR↓, 1,   testos↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 2,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 1,   Ki-67↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Risk↓, 1,  
Total Targets: 18

Pathway results for Effect on Normal Cells:


Functional Outcomes(tgid=23) ⓘ

toxicity↓, 1,  
Total Targets: 1

Scientific Paper Hit Count for: DHT, dihydrotestosterone level
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:457  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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