IL17 Cancer Research Results
IL17, Interleukin-17: Click to Expand ⟱
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Also known as IL-17A.
Interleukin-17A is a protein that in humans is encoded by the IL17A gene.
Higher levels of serum IL-17 are associated with poor prognosis for a variety of solid tumors in cancer patients.
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Scientific Papers found: Click to Expand⟱
*Inflam↓, *IL1↓, *IL6↓, IL17↓, *TNF-α↓,
BMD↑, Cartilage↑, IL17↓, IL22↓, IL23↓, IL28↓, CD4+↓, CD8+↓, LAMB3↑, COL4↓, THBS2↓, ITGA11↓, PPARγ↑, ACAA1↓, PLIN1↓, FABP4↓, PCK1↓, UCP1↓, TNF-α↓,
Dose↝, Casp3↑, MMP9↓, COX2/PTGS2↓, NF-kB↓, PI3K↓, Akt↓, ERK↓, Inflam↓, TNF-α↓, IL6↓, IL17↓, IL22↓, IL23↓,
Inflam↓, TNF-α↓, IL6↓, IL17↓, NF-kB↓, COX2/PTGS2↓, *AntiDiabetic↑, *hepatoP↑, ALAT↓, AST↓, TumCP↓, Apoptosis↑, TumCCA↑, TumAuto↑, tumCV↓, TumCMig↓, Glycolysis↓, ATP↓, lactateProd↓, HK2↓, PKA↓, COX2/PTGS2↓, mtDam↑, Casp3↑, Casp8↑, Casp9↑, Akt↓, ROS↑, MMP↓, P53↑,
Showing Research Papers: 1 to 4 of 4
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress(tgid=1) ⓘ
ROS↑, 1,
Mitochondria & Bioenergetics(tgid=3) ⓘ
ATP↓, 1, MMP↓, 1, mtDam↑, 1, UCP1↓, 1,
Core Metabolism/Glycolysis(tgid=4) ⓘ
ACAA1↓, 1, ALAT↓, 1, FABP4↓, 1, Glycolysis↓, 1, HK2↓, 1, lactateProd↓, 1, PCK1↓, 1, PLIN1↓, 1, PPARγ↑, 1,
Cell Death(tgid=5) ⓘ
Akt↓, 2, Apoptosis↑, 1, Casp3↑, 2, Casp8↑, 1, Casp9↑, 1,
Transcription & Epigenetics(tgid=7) ⓘ
tumCV↓, 1,
Autophagy & Lysosomes(tgid=9) ⓘ
TumAuto↑, 1,
DNA Damage & Repair(tgid=10) ⓘ
P53↑, 1,
Cell Cycle & Senescence(tgid=11) ⓘ
TumCCA↑, 1,
Proliferation, Differentiation & Cell State(tgid=12) ⓘ
ERK↓, 1, PI3K↓, 1,
Migration(tgid=13) ⓘ
Cartilage↑, 1, COL4↓, 1, ITGA11↓, 1, LAMB3↑, 1, MMP9↓, 1, PKA↓, 1, THBS2↓, 1, TumCMig↓, 1, TumCP↓, 1,
Immune & Inflammatory Signaling(tgid=16) ⓘ
CD4+↓, 1, COX2/PTGS2↓, 3, IL17↓, 4, IL22↓, 2, IL23↓, 2, IL28↓, 1, IL6↓, 2, Inflam↓, 2, NF-kB↓, 2, TNF-α↓, 3,
Drug Metabolism & Resistance(tgid=21) ⓘ
Dose↝, 1,
Clinical Biomarkers(tgid=22) ⓘ
ALAT↓, 1, AST↓, 1, BMD↑, 1, IL6↓, 2,
Infection & Microbiome(tgid=24) ⓘ
CD8+↓, 1,
Total Targets: 50
Pathway results for Effect on Normal Cells:
Immune & Inflammatory Signaling(tgid=16) ⓘ
IL1↓, 1, IL6↓, 1, Inflam↓, 1, TNF-α↓, 1,
Clinical Biomarkers(tgid=22) ⓘ
IL6↓, 1,
Functional Outcomes(tgid=23) ⓘ
AntiDiabetic↑, 1, hepatoP↑, 1,
Total Targets: 7
Scientific Paper Hit Count for: IL17, Interleukin-17
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:0 prod#:% Target#:540 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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