IL23 Cancer Research Results
IL23, Interleukin 23: Click to Expand ⟱
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A heterodimeric cytokine composed of an IL-12B subunit and an IL-23A subunit. IL-23 is part of the IL-12 family of cytokines.
IL-23 is an inflammatory cytokine. IL-23 is overexpressed in a number of cancer types.
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Scientific Papers found: Click to Expand⟱
BMD↑, Cartilage↑, IL17↓, IL22↓, IL23↓, IL28↓, CD4+↓, CD8+↓, LAMB3↑, COL4↓, THBS2↓, ITGA11↓, PPARγ↑, ACAA1↓, PLIN1↓, FABP4↓, PCK1↓, UCP1↓, TNF-α↓,
Dose↝, Casp3↑, MMP9↓, COX2/PTGS2↓, NF-kB↓, PI3K↓, Akt↓, ERK↓, Inflam↓, TNF-α↓, IL6↓, IL17↓, IL22↓, IL23↓,
Showing Research Papers: 1 to 2 of 2
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2
Pathway results for Effect on Cancer / Diseased Cells:
Mitochondria & Bioenergetics(tgid=3) ⓘ
UCP1↓, 1,
Core Metabolism/Glycolysis(tgid=4) ⓘ
ACAA1↓, 1, FABP4↓, 1, PCK1↓, 1, PLIN1↓, 1, PPARγ↑, 1,
Cell Death(tgid=5) ⓘ
Akt↓, 1, Casp3↑, 1,
Proliferation, Differentiation & Cell State(tgid=12) ⓘ
ERK↓, 1, PI3K↓, 1,
Migration(tgid=13) ⓘ
Cartilage↑, 1, COL4↓, 1, ITGA11↓, 1, LAMB3↑, 1, MMP9↓, 1, THBS2↓, 1,
Immune & Inflammatory Signaling(tgid=16) ⓘ
CD4+↓, 1, COX2/PTGS2↓, 1, IL17↓, 2, IL22↓, 2, IL23↓, 2, IL28↓, 1, IL6↓, 1, Inflam↓, 1, NF-kB↓, 1, TNF-α↓, 2,
Drug Metabolism & Resistance(tgid=21) ⓘ
Dose↝, 1,
Clinical Biomarkers(tgid=22) ⓘ
BMD↑, 1, IL6↓, 1,
Infection & Microbiome(tgid=24) ⓘ
CD8+↓, 1,
Total Targets: 30
Pathway results for Effect on Normal Cells:
Total Targets: 0
Scientific Paper Hit Count for: IL23, Interleukin 23
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:0 prod#:% Target#:543 State#:% Dir#:1
wNotes=0 sortOrder:rid,rpid
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