E-sel Cancer Research Results

E-sel, E-selectin: Click to Expand ⟱
Source:
Type:
E-selectin is a cell adhesion molecule that plays a crucial role in the recruitment of leukocytes to sites of inflammation. In cancer, E-selectin is involved in the interaction between tumor cells and the endothelium, promoting metastasis and tumor progression.

E-selectin is expressed on the surface of endothelial cells in tumors, and its expression is associated with increased metastasis and poor prognosis.
Scientific Papers found: Click to Expand⟱
9119- Cim,    An interesting change of E-selectin in cimetidine administration during anticancer drug use
- in-vitro, GC, NA - in-vitro, CRC, NA
E-sel↓,
9116- Cim,    Cimetidine increases survival of colorectal cancer patients with high levels of sialyl Lewis-X and sialyl Lewis-A epitope expression on tumour cells
- Trial, CRC, NA
eff↑, Dose↝, OS↑, E-sel↓, TumCA↓,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Migration(tgid=13) ⓘ

TumCA↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

E-sel↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 1,   eff↑, 1,  

Functional Outcomes(tgid=23) ⓘ

OS↑, 1,  
Total Targets: 5

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: E-sel, E-selectin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:954  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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