adiP Cancer Research Results

adiP, adiponectin: Click to Expand ⟱
Source:
Type:
Adiponectin is an adipokine with anti-inflammatory and insulin-sensitizing properties, and its effects on tumor biology are thought to be mediated through influences on cell proliferation, apoptosis, and metabolic regulation.

Adiponectin is a key metabolic hormone whose levels have been associated with cancer risk and prognosis across multiple tumor types. Generally, lower adiponectin levels tend to correlate with more aggressive tumor phenotypes and poorer outcomes, while higher levels may offer a degree of protection.
Scientific Papers found: Click to Expand⟱
1854- dietFMD,    How Far Are We from Prescribing Fasting as Anticancer Medicine?
- Review, Var, NA
ChemoSideEff↓, ChemoSen↑, IGF-1↓, IGFBP1↑, adiP↑, glyC↓, E-cadherin↑, MMPs↓, Casp3↑, ROS↑, ATP↓, AMPK↑, mTOR↓, ROS↑, Glycolysis↓, NADPH↓, OXPHOS↝, eff↑, eff↑, *RAS↓, *MAPK↓, *PI3K↓, *Akt↓, eff↑, ROS↑, Akt↑, Casp3↑,
5192- dietMet,    Intermittent methionine restriction reduces IGF‐1 levels and produces similar healthspan benefits to continuous methionine restriction
OS↑, eff↝, IGF-1↓, adiP↑, Leptin↓, Weight↓,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

OXPHOS↝, 1,   ROS↑, 3,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

adiP↑, 2,   AMPK↑, 1,   glyC↓, 1,   Glycolysis↓, 1,   NADPH↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↑, 1,   Casp3↑, 2,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

IGF-1↓, 2,   IGFBP1↑, 1,   mTOR↓, 1,  

Migration(tgid=13) ⓘ

E-cadherin↑, 1,   MMPs↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

Leptin↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ChemoSen↑, 1,   eff↑, 3,   eff↝, 1,  

Functional Outcomes(tgid=23) ⓘ

ChemoSideEff↓, 1,   OS↑, 1,   Weight↓, 1,  
Total Targets: 22

Pathway results for Effect on Normal Cells:


Cell Death(tgid=5) ⓘ

Akt↓, 1,   MAPK↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

PI3K↓, 1,   RAS↓, 1,  
Total Targets: 4

Scientific Paper Hit Count for: adiP, adiponectin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:1191  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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