Imm Cancer Research Results

Imm, immunostimulatory: Click to Expand ⟱
Source:
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Enhance the immune response in patients.
Scientific Papers found: Click to Expand⟱
5270- 5-ALA,  PDT,    5-Aminolevulinic Acid as a Theranostic Agent for Tumor Fluorescence Imaging and Photodynamic Therapy
- Review, Var, NA
other↝, ROS↑, other↝, mtDam↑, Ca+2↑, ER Stress↑, Apoptosis↑, TumAuto↑, other↝, Dose↝, Imm↑,
5431- AG,    Advances in research on the anti-tumor mechanism of Astragalus polysaccharides
- Review, Var, NA
AntiTum↑, TumCG↓, TumCI↓, Apoptosis↑, Imm↑, Bcl-2↓, BAX↑, Wnt↓, β-catenin/ZEB1↓, TumCG↓, miR-133a-3p↑, JNK↓, Fas↑, P53↑, P21↑, NOTCH1↓, NOTCH3↓, TumCP↓, TumCCA↑, GPx4↓, xCT/SLC7A11↓, AMPK↑, Beclin-1/ATG6↑, NF-kB↓, EMT↓, Vim↓, TumMeta↓, VEGF↓, EGFR↓, eff↑, eff↑, MMP↓, P-gp/ABCB1↓, MMP9↓, ChemoSen↑, SIRT1↓, SREBP1/SREBF1↓, TumAuto↑, PI3K↓, mTOR↓, Casp3↑, Casp9↑, CD133↓, CD44↓, CSCs↓, QoL↑,
5432- AG,    Astragalus polysaccharides combined with radiochemotherapy for cervical cancer: a systematic review and meta-analysis of randomized controlled studies
- Review, Cerv, NA
ChemoSen↑, eff↑, RadioS↑, CEA↓, Wnt↓, β-catenin/ZEB1↓, γH2AX↑, ER Stress↑, mt-TumAuto↑, QoL↑, Imm↑,
5434- AG,    Recent Advances in the Mechanisms and Applications of Astragalus Polysaccharides in Liver Cancer Treatment: An Overview
- Review, Liver, NA
AntiCan↑, Apoptosis↑, TumCP↓, EMT↓, Imm↑, ChemoSen↑, BioAv↓, TumCG↓, IL2↑, IL12↑, TNF-α↑, P-gp/ABCB1↓, MDR1↓, QoL↑, Casp↑, DNAdam↑, Bcl-2↓, BAX↑, MMP↓, Cyt‑c↑, NOTCH1↓, GSK‐3β↓, TumCCA↑, GSH↓, ROS↑, lipid-P↑, c-Iron↑, GPx4↓, ACSL4↑, Ferroptosis↑, Wnt↓, β-catenin/ZEB1↓, cycD1/CCND1↓, Akt↓, PI3K↓, mTOR↓, CXCR4↓, Vim↓, PD-L1↓, eff↑, eff↑, ChemoSen↑, ChemoSen↑, chemoP↑,
7400- Amla,    Amla (Emblica officinalis Gaertn), a wonder berry in the treatment and prevention of cancer
- Review, Var, NA
radioP↑, ChemoSen↑, chemoPv↑, *ROS↓, antiOx↑, Inflam↓, Imm↑, *hepatoP↑, *cardioP↑, *lipid-P↓, TumCCA↑, Chk2↑, CDK1↓, CycB/CCNB1↓, CDC25↓, TumMeta↓,
5409- ASA,    Role of aspirin in cancer prevention
- Review, Var, NA
Imm↑, *Inflam↓, *AntiAg↑, *GutMicro↑, eff↑, TumMeta↓, angioG↓, Risk↓, Risk↓,
5572- B-Gluc,    The Effects of Orally Administered Beta-Glucan on Innate Immune Responses in Humans, a Randomized Open-Label Intervention Pilot-Study
- Study, Nor, NA
Imm↑, *Dose↝, *BioAv↓, *toxicity↑,
5571- B-Gluc,  immuno,    Potential benefit of β-glucans as adjuvant therapy in immuno-oncology: a review
- Review, Var, NA
Imm↑, ChemoSen↑, LDL↑, GutMicro↑, TumCP↓, Apoptosis↑, angioG↓, QoL↑,
5570- B-Gluc,    Immunomodulation of Fungal β-Glucan in Host Defense Signaling by Dectin-1
- Review, Var, NA
Imm↑, BioAv↝, eff↑, AntiCan↑, Dectin1↝, Dose↝, BioAv↓,
5569- B-Gluc,    Leveraging glucan-induced trained immunity for the epigenetic and metabolic rewiring of macrophages to enhance colorectal cancer vaccine response
- in-vitro, CRC, NA
Imm↑,
5568- B-Gluc,  immuno,    Beta-glucans in oncology: revolutionizing treatment with immune power & tumor targeting
- Review, Var, NA
TNF-α↓, IL6↓, NF-kB↓, PD-L1↓, Imm↑, BAX↑, Bcl-2↓, TumCCA↑, angioG↓, VEGF↓, MMPs↓, OS↑, chemoP↑, eff↑, BioAv↑,
5567- B-Gluc,    Trained immunity: A new player in cancer immunotherapy
- Review, Var, NA
Imm↑, ROS↑, Apoptosis↑, OS↑, TumMeta↓, Dose↝,
5566- B-Gluc,    The effects of beta-glucan on human immune and cancer cells
- Review, Var, NA
Imm↑, *BioAv↓, OS↑, ChemoSen↑,
5575- B-Gluc,    The effects of β-glucan on human immune and cancer cells
- Review, Var, NA
Imm↑, *toxicity↓, eff↑, Imm↑,
5577- B-Gluc,    Lentinan progress in inflammatory diseases and tumor diseases
- Review, Var, NA - Review, IBD, NA
AntiTum↑, GutMicro↑, *Inflam↓, *TNF-α↓, *NF-kB↓, ChemoSen↑, OS↑, Imm↑, IL6↓, ERK↓, MAPK↓, *antiOx↑, eff↑,
5579- B-Gluc,    Fungal beta-glucans as adjuvants for treating cancer patients – A systematic review of clinical trials
- Review, Var, NA
*toxicity↓, Imm↑, radioP↑, chemoP↑,
5580- B-Gluc,    Lentinan, a Shiitake Mushroom β-Glucan, Downregulates the Enhanced PD-L1 Expression Induced by Platinum Compounds in Gastric Cancer Cells
- in-vitro, GC, MKN45
PD-L1↓, MAPK↓, OS↑, AntiTum↑, Imm↑,
5517- BEV,    Exploring the Immunological Mechanisms Underlying the Anti-vascular Endothelial Growth Factor Activity in Tumors
- Review, Var, NA
VEGF↓, Imm↑, eff↑,
5622- Bif,    Bifidobacterium bifidum strains synergize with immune checkpoint inhibitors to reduce tumour burden in mice
- in-vivo, Var, NA
eff↑, Imm↑, IFN-γ↑,
5626- Bif,    Bifidobacterium in anticancer immunochemotherapy: friend or foe?
- Review, Var, NA
*Inflam↓, *Treg lymp↑, *IL10?, Imm↑, eff↑,
5628- Bif,  immuno,    Bifidobacterium modulation of tumor immunotherapy and its mechanism
- Review, Var, NA
Imm↑, Risk↓, GutMicro↑, AntiTum↑, OS↑, selectivity↑, eff↑,
5680- BML,    Anticancer properties of bromelain: State-of-the-art and recent trends
- Review, Var, NA
*Inflam↓, *Bacteria↓, *Pain↓, *Diar↓, *Wound Healing↑, ERK↓, JNK↓, XIAP↓, HSP27↓, β-catenin/ZEB1↓, HO-1↓, lipid-P↓, ACSL4↑, ROS↑, SOD↑, Catalase↓, GSH↓, MDA↓, Casp3↓, Casp9↑, DNAdam↑, Apoptosis↑, NF-kB↓, P53↑, MAPK↓, APAF1↑, Cyt‑c↓, CD44↓, Imm↑, ATG5↑, LC3I↑, Beclin-1/ATG6↑, IL2↓, IL4↓, IFN-γ↓, COX2/PTGS2↓, iNOS↓, ChemoSen↑, RadioS↑, Dose↝, other↓,
5646- BP,    Black Phosphorus, an Emerging Versatile Nanoplatform for Cancer Immunotherapy
- Review, Var, NA
ROS↑, Imm↑, PhotoS↑,
5739- Buty,    Butyrate as a promising therapeutic target in cancer: From pathogenesis to clinic (Review)
- Review, Var, NA
GutMicro↑, *Inflam↓, *IL6↓, *TNF-α↓, *IL17↓, *IL10↑, *ROS↝, COX2/PTGS2↓, NLRP3↓, Imm↑, HDAC↓, TumCCA↑, Apoptosis↑, ROS↑, Casp↑, mtDam↑, Cyt‑c↑, eff↑, chemoP↑, ChemoSen↑, eff↑, RadioS↑, HCAR2↑,
5735- Buty,    Butyrate and the Intestinal Epithelium: Modulation of Proliferation and Inflammation in Homeostasis and Disease
- Study, Nor, NA
*Inflam↓, GutMicro↑, Imm↑,
5837- CAP,    Capsaicin triggers immunogenic PEL cell death, stimulates DCs and reverts PEL-induced immune suppression
- in-vitro, lymphoma, PEL
STAT3↓, Imm↑,
5916- Cats,  Chemo,    Uncaria tomentosa—Adjuvant Treatment for Breast Cancer: Clinical Trial
- Trial, BC, NA
*DNAdam↓, Neut↓, eff↑, Imm↑, Dose↝,
6030- CGA,    Chlorogenic acid induces apoptosis, inhibits metastasis and improves antitumor immunity in breast cancer via the NF‑κB signaling pathway
- vitro+vivo, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-453 - in-vitro, Nor, MCF10
NF-kB↓, AntiTum↑, tumCV↓, TumCP↓, Apoptosis↑, TumCMig↓, TumCI↓, EMT↓, TumCG↓, OS↑, TumMeta↓, CD4+↑, CD8+↑, Imm↑,
5980- Chit,    Chitosan-based nanosystems for cancer diagnosis and therapy: Stimuli-responsive, immune response, and clinical studies
- Review, Var, NA
other↑, Imm↑, DDS↑,
5988- Chit,    Chitosan immunomodulation: insights into mechanisms of action on immune cells and signaling pathways
- Review, Var, NA
DDS↑, *Cartilage↑, *Wound Healing↑, Imm↑, cGAS–STING↑, STAT1↑, NLRP3↑, *DCells↑, *IL10↓, *TGF-β1↓, *TNF-α↓, IL1β↓, ROS↑,
5989- Chit,    Chitosan: A review of molecular structure, bioactivities and interactions with the human body and micro-organisms
- Review, Var, NA
Wound Healing↑, Imm↑, AntiTum↑,
5997- Chit,    Using immunoadjuvant agent glycated chitosan to enhance anti-cancer stem like cell immunity induced by HIFU
- in-vivo, Lung, NA
Imm↑, TumMeta↓, eff↑,
5993- Chit,    In vivo stepwise immunomodulation using chitosan nanoparticles as a platform nanotechnology for cancer immunotherapy
- in-vitro, Var, NA
Imm↑,
6374- CPLE,    Antiviral & platelet-protective properties of Carica papaya in dengue
- Review, Nor, NA
*antiOx↑, *lipid-P↓, *AntiTum↑, Imm↑, CIT↓,
6520- CRV,    Health Benefits and Pharmacological Properties of Carvone
- Review, Nor, NA
*Bacteria↓, *AntiFungal↑, *antiOx↑, *Inflam↓, AntiCan↑, *AntiDiabetic↑, *Obesity↓, TumCCA↑, *AntiArt↑, Imm↑, *P450↓, *GSR↑, GSTs↑, GSH↑, BAX↑, Casp3↑, TumCP↓, TumCMig↓, Apoptosis↑,
6203- Cuc,  immuno,    Isocucurbitacin B targets STAT3 to induce ferroptosis and promote anti-PD1 immunotherapy responses in breast cancer
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, BT549 - in-vivo, BC, 4T1
Ferroptosis↑, STAT3↓, GPx4↓, Imm↑, PD-L1↓, TumCG↓, ATP↓, OXPHOS↓,
6214- CUR,    Curcumin Nanoparticles-related Non-invasive Tumor Therapy, and Cardiotoxicity Relieve
TumCD↓, TumCI↓, *Inflam↓, *antiOx↓, *AntiTum↓, NF-kB↓, COX2/PTGS2↓, Casp9↓, ROS↑, BioAv↑, RadioS↑, ChemoSen↑, Imm↑, PhotoS↑, sonoS↑, 5LO↓, iNOS↓, IL2↓, TNF-α↓, Casp9↑, Casp3↑, Bcl-2↓, BAX↑, Apoptosis↑, ER Stress↑, cycD1/CCND1↓, CDK2↓, CycB/CCNB1↓, TumCCA↑, MMPs↓, *radioP↑, chemoP↑, hepatoP↑, cardioP↑, eff↑, PhotoS↑, eff↑, ROS↑, GSH↓,
6223- CUR,    Curcumin Rewires the Tumor Metabolic Landscape: Mechanisms and Clinical Prospects
- Review, Var, NA
Ferroptosis↑, GutMicro↑, Akt↓, mTOR↓, NF-kB↓, Wnt↓, β-catenin/ZEB1↓, STAT3↓, TumCP↓, TumCI↓, TumMeta↓, AMPK↑, P53↑, NRF2↑, TumCCA↑, Apoptosis↑, Casp↑, GPx4↓, DNMTs↓, HDAC↓, VEGF↓, Imm↑, NK cell↑, Warburg↓, Hif1a↓, HK2↓, PKM2↓, LDHA↓, GLUT1↓, MCT1↓, AMPK↑, FASN↓, SCD1↓, GLS↓, Apoptosis↑, ETC↓, MMP↓, ROS↑, lipid-P↑, ChemoSen↑, PDK1 / PDPK1↓, Beclin-1/ATG6↓, ATP↓, Glycolysis↓, GlucoseCon↓, lactateProd↑, MMPs↓, GSH↓, G6PD↓, OXPHOS↓, SREBP2↓, COX2/PTGS2↓, AP-1↓, NADH↓, NRF2↑, HO-1↑, Iron↑, MDA↑, *ROS↓, *Inflam↓,
6221- CUR,    Oxidative Stress and Cancer: Harnessing the Therapeutic Potential of Curcumin and Analogues Against Cancer
- Review, Var, NA
NF-kB↓, Imm↑, *TAC↑, *MDA↓, ROS↑, TumAuto↑, TumCCA↑, Keap1↑, ChemoSen↑, ER Stress↑, eff↓, TrxR↓, STAT3↓, *BioAv↓,
6749- DHA,    The effects of docosahexaenoic acid (DHA) on plasma cytokines, oxylipins, and tumor-infiltrating lymphocytes from women with breast cancer undergoing neoadjuvant chemotherapy in the DHA-WIN trial
- Trial, BC, NA
*IFN-γ↑, *TNF-α↑, Imm↑,
6750- DHA,  Chemo,    Docosahexaenoic acid (DHA) supplementation attenuates changes in the concentration, phenotype, and response of immune peripheral blood cells in breast cancer patients undergoing neoadjuvant therapy. Secondary findings from the DHA-WIN trial
- Trial, BC, NA
*CD14↑, *NLR↓, eff↑, *IL4↑, *IL10↑, *IFN-γ↑, *TNF-α↑, Imm↑, eff↑, TumW↓,
5065- dietSTF,  dietFMD,    Nutrition, GH/IGF-I Signaling, and Cancer
- Review, Var, NA
GH↓, IGF-1↓, glucose↓, IGFBP1↑, OS↑, Imm↑, neuroP↑, BMD↑, Dose↝, Risk↓, other↑, TumCP↓,
5071- dietSTF,    Unraveling the impact of intermittent fasting in cancer prevention, mitigation, and treatment: A narrative review
- Review, Var, NA - Review, AD, NA
Risk↓, TumCMig↓, IGF-1↓, TumAuto↑, Inflam↓, ChemoSen↑, Apoptosis↑, chemoP↑, *glucose↓, *AntiDiabetic↑, *cardioP↑, *LDL↓, *BP↓, *neuroP↑, *cognitive↑, *memory↑, *OS↑, *QoL↑, Imm↑, TumCG↓, ChemoSideEff↓, QoL↑,
6354- DRE,    Taraxacum officinale L. in leukemia and lymphoma: current knowledge and prospects for horticulture
- Review, AML, NA
ROS↑, mt-Apoptosis↑, TumCCA↑, PI3K↓, Akt↓, STAT3↓, Dose↝, *hepatoP↑, Casp8↑, mtDam↑, TumCD↑, selectivity↑, DNAdam↑, BAX↑, P53↑, Bcl-2↓, CSCs↓, *toxicity↓, tumCV↓, Imm↑, FAK↓, mTOR↓, ChemoSen↑, eff↝, eff↑,
4914- DSF,  immuno,    Disulfiram and cancer immunotherapy: Advanced nano-delivery systems and potential therapeutic strategies
- Review, Var, NA
AntiTum↑, eff↑, ALDH↓, Dose↝, RadioS↑, angioG↓, TumMeta↓, BioAv↝, ROS↑, DNAdam↑, P-gp/ABCB1↓, CSCs↓, EMT↓, Imm↑, SOD↓, MAPK↓, NF-kB↓, ChemoSen↑, eff↑, toxicity↝, BioAv↑, *Inflam↓, Sepsis↓,
4916- DSF,  Cu,    The immunomodulatory function and antitumor effect of disulfiram: paving the way for novel cancer therapeutics
- Review, Var, NA
TumCP↓, TumCMig↓, TumCI↓, eff↑, Imm↑, ROS↑, NF-kB↓, chemoP↑, JNK↑, FOXO↑, Myc↑, TumCCA↑, Apoptosis↑, RadioS↑, PD-L1↑, eff↑, CSCs↓, Dose↝, Half-Life↑,
6611- Ech,    Proliferative activity of a blend of Echinacea angustifolia and Echinacea purpurea root extracts in human vein epithelial, HeLa, and QBC-939 cell lines, but not in Beas-2b cell lines
- in-vitro, Cerv, HeLa - in-vitro, Nor, BEAS-2B - in-vitro, Nor, HUVECs
Imm↑, TumCP↑, Telomerase↓, Apoptosis↑, DNAdam↑, Casp9↑, cl‑PARP↑, β-catenin/ZEB1↓,
6613- Ech,    Bioavailability and pharmacokinetics of Echinacea purpurea preparations and their interaction with the immune system
- Study, Nor, NA
*TNF-α↓, *IL8↓, Imm↑,
6603- Ech,  doxoR,    The effect of Echinacea purpurea on the pharmacokinetics of docetaxel
- Trial, Var, NA
other∅, other↝, Imm↑, CYP3A4⇅, other↑,
6607- Ech,    Cytotoxic effects of Echinacea root hexanic extracts on human cancer cell lines
- in-vitro, PC, MIA PaCa-2 - in-vitro, CRC, Colo320
tumCV↓, eff↑, Apoptosis↑, Casp3↑, Casp7↑, DNAdam↑, Imm↑, NK cell↑, PGE2↓, COX1↓, COX2/PTGS2↓, 5LO↓,

Showing Research Papers: 1 to 50 of 104
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 104

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

anemia↓, 1,   APG↓, 1,   ATG13↑, 1,   ATG16L1↑, 1,   CIT↓, 1,   CUL1↝, 1,   CUL5↝, 1,   CX43/GJA1↓, 1,   DHODH↓, 1,   HLA-I/II↑, 1,   IRes↓, 1,   kidSt↓, 1,   LC↑, 1,   Mucositis↓, 1,   NA↑, 1,   PC↑, 1,   PFS↑, 1,   PSEN1/PS1↓, 1,   RBC↑, 2,   RUBCN↓, 1,   THEM4/CTMP↑, 1,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,   ULK1/ATG1↑, 1,   WBC↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 4,   ARE↓, 1,   Catalase↓, 1,   compI↓, 1,   Ferroptosis↑, 6,   GPx4↓, 6,   GSH↓, 5,   GSH↑, 1,   GSTs↑, 1,   HO-1↓, 2,   HO-1↑, 1,   Iron↑, 2,   Iron↝, 1,   c-Iron↑, 1,   Keap1↑, 1,   lipid-P↓, 1,   lipid-P↑, 3,   MDA↓, 1,   MDA↑, 2,   NADH↓, 1,   NRF2↓, 3,   NRF2↑, 2,   OXPHOS↓, 3,   ROS↓, 1,   ROS↑, 32,   selenoP↑, 1,   SOD↓, 1,   SOD↑, 1,   Trx↓, 1,   TrxR↓, 1,   TrxR1↓, 1,   xCT/SLC7A11↓, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 2,   IronCh∅, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 5,   CDC2↓, 1,   CDC25↓, 2,   ETC↓, 2,   ETC↝, 1,   Insulin↓, 1,   MMP↓, 8,   mtDam↑, 6,   PGC-1α↑, 1,   XIAP↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACSL4↑, 2,   ALAT↓, 3,   AMP↑, 1,   AMPK↑, 3,   ATG7↑, 1,   BUN↓, 1,   cMyc↑, 1,   CREB↑, 1,   CYP3A4↓, 1,   CYP3A4⇅, 1,   FASN↓, 1,   G6PD↓, 1,   GLS↓, 1,   glucoNG↓, 1,   glucose↓, 1,   glucose↝, 1,   GlucoseCon↓, 1,   Glycolysis↓, 3,   HK2↓, 2,   lactateProd↑, 1,   LDHA↓, 1,   LDL↓, 1,   LDL↑, 1,   lipoGen↓, 1,   PDK1 / PDPK1↓, 2,   PKM2↓, 1,   SCD1↓, 1,   SIRT1↓, 2,   SIRT1↑, 1,   SREBP1/SREBF1↓, 1,   SREBP2↓, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 12,   APAF1↑, 2,   Apoptosis↓, 1,   Apoptosis↑, 23,   mt-Apoptosis↑, 2,   BAD↑, 1,   BAX↑, 9,   Bax:Bcl2↑, 1,   Bcl-2↓, 9,   Bcl-xL↓, 1,   Casp↑, 6,   Casp3↓, 1,   Casp3↑, 10,   cl‑Casp3↑, 1,   Casp7↑, 2,   Casp8↑, 1,   Casp9↓, 1,   Casp9↑, 8,   cl‑Casp9↑, 1,   Chk2↑, 1,   Cyt‑c↓, 1,   Cyt‑c↑, 5,   DR5↑, 1,   Fas↑, 3,   Ferroptosis↑, 6,   hTERT/TERT↓, 1,   iNOS↓, 2,   JNK↓, 2,   JNK↑, 1,   MAPK↓, 5,   MCT1↓, 1,   MDM2↓, 2,   MOMP↑, 3,   Myc↑, 1,   necrosis↑, 2,   NOXA↑, 1,   p27/CDKN1B↓, 2,   p38↑, 1,   Pyro↑, 2,   survivin↓, 3,   Telomerase↓, 1,   TumCD↓, 1,   TumCD↑, 8,  

Kinase & Signal Transduction(tgid=6) ⓘ

CaMKII ↑, 1,   HCAR2↑, 1,   miR-25-5p↓, 1,   Sp1/3/4↓, 1,   TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

BowelM↑, 1,   ChrMod↑, 1,   other↓, 2,   other↑, 6,   other↝, 10,   other∅, 1,   PhotoS↑, 3,   pRB↓, 1,   p‑pRB↓, 2,   SD↑, 1,   sonoS↑, 1,   tumCV↓, 6,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1,   eIF2α↓, 1,   ER Stress↑, 9,   HSP27↓, 1,   HSP70/HSPA5↑, 1,   HSP90↓, 1,   HSPs↑, 1,   PERK↑, 1,   UPR↑, 2,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG3↑, 1,   ATG5↑, 2,   Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 3,   LC3‑Ⅱ/LC3‑Ⅰ↑, 2,   LC3I↑, 1,   p62↑, 1,   TumAuto↓, 1,   TumAuto↑, 9,   TumAuto↝, 1,   mt-TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

BRCA2↓, 1,   DNAdam↑, 11,   DNArepair↓, 3,   DNArepair↑, 1,   DNMTs↓, 1,   P53↑, 6,   PARP↑, 1,   cl‑PARP↑, 3,   γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CDK2↓, 2,   CDK4↓, 1,   CycB/CCNB1↓, 3,   cycD1/CCND1↓, 4,   cycE/CCNE↓, 1,   P21↓, 2,   P21↑, 1,   TumCCA↑, 24,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

4E-BP1↓, 1,   ALDH↓, 1,   CD133↓, 2,   CD44↓, 3,   p‑cMET↑, 1,   CSCs↓, 9,   Diff↑, 4,   EMT↓, 7,   ERK↓, 5,   FOXO↑, 1,   FOXO1↑, 1,   GH↓, 1,   GSK‐3β↓, 1,   HDAC↓, 2,   HH↓, 1,   IGF-1↓, 2,   IGFBP1↑, 1,   mTOR↓, 6,   NOTCH1↓, 3,   NOTCH3↓, 1,   P70S6K↓, 1,   PI3K↓, 10,   RAS↓, 1,   STAT1↑, 1,   STAT3↓, 6,   TumCG↓, 20,   Wnt↓, 8,  

Migration(tgid=13) ⓘ

5LO↓, 2,   AP-1↓, 1,   Ca+2↑, 7,   CEA↓, 1,   Chl↓, 1,   Cofilin↓, 1,   E-cadherin↑, 1,   FAK↓, 2,   fascin↓, 1,   miR-133a-3p↑, 1,   MMP-10↓, 1,   MMP3↓, 1,   MMP9↓, 2,   MMPs↓, 5,   N-cadherin↓, 1,   Na+↑, 1,   PKCδ↓, 2,   ROCK1↓, 1,   Smad1↓, 1,   Snail↓, 1,   TGF-β↓, 1,   TSC1↑, 1,   TumCA↓, 1,   TumCI↓, 10,   TumCMig↓, 7,   TumCP↓, 18,   TumCP↑, 1,   TumMeta↓, 21,   Vim↓, 2,   β-catenin/ZEB1↓, 9,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 14,   angioG↑, 1,   ATF4↑, 1,   EGFR↓, 3,   EPR↑, 3,   Hif1a↓, 2,   Hypoxia↓, 3,   TAMS↑, 1,   VEGF↓, 9,  

Barriers & Transport(tgid=15) ⓘ

CellMemb↑, 3,   GLUT1↓, 2,   Na+↑, 1,   P-gp/ABCB1↓, 4,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 4,   COX1↓, 1,   COX2/PTGS2↓, 7,   CXCR4↓, 1,   DCells↑, 1,   Dectin1↝, 1,   HCAR2↑, 1,   HMGB1↓, 1,   ICAM-1↓, 1,   IFN-γ↓, 2,   IFN-γ↑, 2,   IL12↑, 1,   IL17↑, 1,   IL18↑, 1,   IL1β↓, 1,   IL2↓, 2,   IL2↑, 2,   IL4↓, 1,   IL6↓, 4,   IL6↑, 1,   Imm↑, 105,   INF-γ↝, 1,   Inflam↓, 9,   pol-M1↑, 1,   M2 MC↓, 1,   Neut↓, 1,   Neut↑, 2,   NF-kB↓, 15,   NK cell↑, 11,   PD-L1↓, 5,   PD-L1↑, 1,   PGE2↓, 2,   T-Cell↑, 1,   TLR4↓, 1,   TNF-α↓, 3,   TNF-α↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

cGAS–STING↑, 2,   pH↑, 4,   pH↝, 2,   e-pH↓, 1,   e-pH↑, 2,  

Protein Aggregation(tgid=19) ⓘ

NLRP3↓, 1,   NLRP3↑, 1,   PP2A↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CDK6↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 1,   BioAv↓, 3,   BioAv↑, 8,   BioAv↝, 4,   BioEnh↑, 1,   ChemoSen↑, 34,   DDS↑, 2,   Dose↓, 1,   Dose↑, 3,   Dose↝, 24,   eff↓, 3,   eff↑, 51,   eff↝, 2,   Half-Life↑, 1,   MDR1↓, 1,   RadioS↑, 16,   selectivity↑, 10,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 3,   AST↓, 2,   BloodF↑, 3,   BMD↑, 1,   CA19-9↓, 1,   CEA↓, 1,   creat↓, 1,   EGFR↓, 3,   GutMicro↑, 8,   hTERT/TERT↓, 1,   IL6↓, 4,   IL6↑, 1,   Myc↑, 1,   PD-L1↓, 5,   PD-L1↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↓, 1,   AntiCan↑, 8,   antiNeop↑, 1,   AntiTum↑, 9,   Appetite↑, 1,   breath↑, 1,   cardioP↑, 1,   chemoP↑, 15,   chemoPv↑, 2,   ChemoSideEff↓, 1,   hepatoP↑, 3,   neuroP↑, 2,   NP/CIPN↓, 1,   OS↑, 13,   OS⇅, 1,   Pain↓, 3,   PRAS40↑, 1,   QoL↑, 11,   radioP↑, 3,   Remission↑, 1,   RenoP↑, 1,   Risk↓, 8,   Risk↑, 1,   Sleep↑, 1,   Strength↑, 2,   toxicity↓, 11,   toxicity↝, 2,   TumVol↓, 3,   TumW↓, 3,   Weight↑, 2,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

CD8+↑, 6,   Dectin1↝, 1,   Sepsis↓, 1,  
Total Targets: 380

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

anemia↓, 1,   AntiBio↑, 2,   Aβ42↓, 1,   FPN↑, 1,   NA↝, 1,   NLR↓, 1,   RBC↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 2,   antiOx↑, 8,   Catalase↑, 1,   Fenton↓, 1,   GPx↑, 4,   GSH↑, 2,   GSR↑, 1,   Iron∅, 1,   lipid-P↓, 5,   MDA↓, 1,   NRF2↑, 1,   ROS↓, 9,   ROS↝, 1,   SOD↑, 3,   TAC↑, 2,   TBARS↓, 1,   TrxR↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   TfR1/CD71↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 2,   glucose↓, 1,   LDL↓, 2,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↑, 1,   Apoptosis↓, 2,   Casp3↓, 1,   MAPK↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,   P53↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

P21↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

EMT↓, 1,   mTOR↓, 2,   PTEN↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   Cartilage↑, 1,   TGF-β↓, 1,   TGF-β1↓, 1,   Treg lymp↑, 1,   β-Endo↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

Hif1a↑, 1,   NO↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD14↑, 1,   CD4+↑, 1,   CRP↓, 1,   DCells↑, 1,   IFN-γ↑, 2,   IL10?, 1,   IL10↓, 1,   IL10↑, 2,   IL17↓, 1,   IL2↑, 1,   IL4↑, 2,   IL6↓, 5,   IL8↓, 1,   Inflam↓, 14,   NF-kB↓, 1,   NK cell↑, 2,   TNF-α↓, 8,   TNF-α↑, 2,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   tau↓, 1,   p‑tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,   NLRP3↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

TSHR↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 5,   BioAv↑, 5,   BioAv↝, 1,   ChemoSen↑, 1,   Dose↝, 2,   eff↑, 4,   P450↓, 1,  

Clinical Biomarkers(tgid=22) ⓘ

BMD↑, 1,   BP↓, 1,   CRP↓, 1,   Ferritin↓, 1,   GutMicro↑, 4,   HemoG↑, 1,   IL6↓, 5,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   AntiArt↑, 1,   AntiCan↑, 1,   AntiDiabetic↑, 4,   AntiP↑, 1,   AntiTum↓, 1,   AntiTum↑, 2,   cardioP↑, 5,   chemoP↑, 1,   cognitive↑, 2,   hepatoP↑, 3,   memory↑, 1,   neuroP↑, 3,   Obesity↓, 2,   OS↑, 2,   Pain↓, 1,   QoL↑, 1,   radioP↑, 1,   RenoP↑, 1,   toxicity↓, 7,   toxicity↑, 2,   toxicity↝, 2,   Wound Healing↑, 3,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 2,   AntiViral↑, 2,   Bacteria↓, 3,   CD8+↑, 1,   Diar↓, 1,   Sepsis↓, 1,  
Total Targets: 117

Scientific Paper Hit Count for: Imm, immunostimulatory
11 beta-glucans
7 immunotherapy
6 Electrical Pulses
6 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
6 Bicarbonate(Sodium)
5 chitosan
5 Echinacea
5 Hyperthermia
5 Inositol
5 Lactoferrin/Talactoferrin
4 Curcumin
4 Radiotherapy/Radiation
3 Astragalus
3 Bifidobacterium
3 Chemotherapy
3 Selenite (Sodium)
2 Butyrate
2 Docosahexaenoic Acid
2 diet Short Term Fasting
2 Disulfiram
2 doxorubicin
2 Germanium Organic/Ge-132 / propagermanium (organogermanium)
2 Isobavachalcone
2 Inulin Prebiotic
2 Magnetic Field Rotating
2 Magnetic Fields
2 Selenium
1 5-Aminolevulinic acid
1 Photodynamic Therapy
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Aspirin
1 Bevacizumab (brand Avastin)
1 Bromelain
1 Black phosphorus
1 Capsaicin
1 Cat’s Claw
1 Chlorogenic acid
1 Carica papaya leaf extract
1 Carvone
1 Cucurbitacin
1 diet FMD Fasting Mimicking Diet
1 Dandelion Root
1 Copper and Cu NanoParticles
1 EGCG (Epigallocatechin Gallate)
1 Ginkgetin
1 Gossypol/AT-101
1 hydroxychloroquine
1 Gemcitabine (Gemzar)
1 Paclitaxel/Taxol
1 iodine
1 metronomic chemo
1 Hydrogen Gas
1 Ivermectin
1 Licochalcone A
1 Luteolin
1 Metformin
1 Selenium NanoParticles
1 Urolithin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:1332  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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