PSADT Cancer Research Results

PSADT, Prostate-Specific Antigen Doubling Time: Click to Expand ⟱
Source:
Type:

PSADT (Prostate-Specific Antigen Doubling Time) — Measure of PSA kinetics representing the estimated time required for serum prostate-specific antigen (PSA) concentration to double. PSADT is typically calculated from serial PSA measurements using the slope of log-transformed PSA versus time.

Typical interpretation in prostate cancer: ↓ PSADT (shorter doubling time) generally indicates faster PSA rise, more aggressive tumor behavior, and greater risk of disease progression or recurrence. ↑ PSADT (longer doubling time) generally indicates slower PSA progression and a more indolent disease course.

Typical use: Prognostic and monitoring biomarker in prostate cancer, particularly after definitive treatment or during biochemical recurrence. PSADT should be interpreted together with absolute PSA, treatment history, Gleason grade, stage, imaging, and other clinical variables.
Scientific Papers found: Click to Expand⟱
8813- MCP,    Modified citrus pectin (MCP) increases the prostate-specific antigen doubling time in men with prostate cancer: a phase II pilot study
- Trial, Pca, NA
PSADT↑,
8814- MCP,    Modified Citrus Pectin Treatment in Non-Metastatic Biochemically Relapsed Prostate Cancer: Long-Term Results of a Prospective Phase II Study
- Trial, Pca, NA
*toxicity↓, Gal-3?, PSADT↑, Dose↝, PSA↓, PSADT↑,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Immune & Inflammatory Signaling(tgid=16) ⓘ

Gal-3?, 1,   PSA↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

PSA↓, 1,   PSADT↑, 3,  
Total Targets: 5

Pathway results for Effect on Normal Cells:


Functional Outcomes(tgid=23) ⓘ

toxicity↓, 1,  
Total Targets: 1

Scientific Paper Hit Count for: PSADT, Prostate-Specific Antigen Doubling Time
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:1892  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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