CellShr Cancer Research Results

CellShr, cell shrinkage: Click to Expand ⟱
Source:
Type:

Cell Shrinkage — Reduction in cellular volume and cytoplasmic size, commonly observed as an early morphologic feature of apoptosis. It is often accompanied by cytoplasmic condensation, chromatin condensation, membrane blebbing, and eventual formation of apoptotic bodies.

Typical modulation in cancer: ↑ cell shrinkage is generally favorable when it reflects induction of apoptosis or treatment-related tumor-cell death. However, cell shrinkage alone is not specific for apoptosis and should ideally be interpreted together with other markers such as caspase activation, Annexin V positivity, DNA fragmentation, or nuclear condensation.

Typical mechanistic relationship: Apoptotic signaling → ion and water loss → cell volume decrease → cytoplasmic condensation → membrane blebbing / apoptotic body formation.
Scientific Papers found: Click to Expand⟱
9012- Phyco,    Phycocyanin from Arthrospira platensis as Potential Anti-Cancer Drug: Review of In Vitro and In Vivo Studies
- Review, Var, NA
*Ingr↝, *antiOx↑, *Inflam↓, Imm↑, AntiCan↑, *toxicity↓, *Dose↝, *GutMicro↑, *IBI↑, Apoptosis↑, TumCCA↑, DNArepair↓, ROS↑, Cyt‑c↑, BAX↑, cl‑PARP1↑, CellShr↑, TumCMig↓, COX2/PTGS2↓, E-cadherin↑, MMP2↓, MMP9↓, HIF-1↓, angioG↓, MCP1/CCL2↓, MIP-1β↑, Ca+2↑, Cal9↑, Wnt↓, β-catenin/ZEB1↓, PPARα↑, PPARγ↑, eff↝, Half-Life↓, Synergy↑, ChemoSen↑, chemoP↑, EMT↓, N-cadherin↓, E-cadherin↑, TumCMig↓, TumCI↓, selectivity↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

ROS↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 1,   BAX↑, 1,   CellShr↑, 1,   Cyt‑c↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNArepair↓, 1,   cl‑PARP1↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Wnt↓, 1,  

Migration(tgid=13) ⓘ

Ca+2↑, 1,   Cal9↑, 1,   E-cadherin↑, 2,   EMT↓, 1,   MMP2↓, 1,   MMP9↓, 1,   N-cadherin↓, 1,   TumCI↓, 1,   TumCMig↓, 2,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   HIF-1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   Imm↑, 1,   MCP1/CCL2↓, 1,   MIP-1β↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

PPARα↑, 1,   PPARγ↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ChemoSen↑, 1,   eff↝, 1,   Half-Life↓, 1,   selectivity↑, 1,   Synergy↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   chemoP↑, 1,  
Total Targets: 34

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,  

Barriers & Transport(tgid=15) ⓘ

IBI↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Inflam↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 1,  

Functional Outcomes(tgid=23) ⓘ

toxicity↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

GutMicro↑, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 1,  
Total Targets: 7

Scientific Paper Hit Count for: CellShr, cell shrinkage
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:1911  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

Home Page