OS Cancer Research Results

OS, overall survival: Click to Expand ⟱
Source:
Type:
Overall survival

Scientific Papers found: Click to Expand⟱
2326- 2DG,    Caloric Restriction Mimetic 2-Deoxyglucose Alleviated Inflammatory Lung Injury via Suppressing Nuclear Pyruvate Kinase M2–Signal Transducer and Activator of Transcription 3 Pathway
- in-vivo, Nor, NA
PKM2↓, Inflam↓, TNF-α↓, IL6↓, OS↑,
5281- 3BP,    A translational study “case report” on the small molecule “energy blocker” 3-bromopyruvate (3BP) as a potent anticancer agent: from bench side to bedside
- Case Report, Var, NA
Glycolysis↓, mt-OXPHOS↓, ATP↓, selectivity↑, toxicity↝, OS↑, QoL↑,
5278- 3BP,    The effect of 3-bromopyruvate on human colorectal cancer cells is dependent on glucose concentration but not hexokinase II expression
- in-vitro, CRC, HCT116 - in-vitro, CRC, Caco-2 - in-vitro, CRC, SW48
ATP↓, TumCD↑, selectivity↑, toxicity↓, OS↑, HK2?, Cyt‑c↑, eff↑, p‑Akt↑,
5264- 3BP,    Candidate cancer drug suspected after death of three patients at an alternative medicine clinic
- Review, Var, NA
toxicity↑, Glycolysis↓, eff↑, OS↑, QoL↑, toxicity↝,
5467- AF,    Auranofin Inhibition of Thioredoxin Reductase Sensitizes Lung Neuroendocrine Tumor Cells (NETs) and Small Cell Lung Cancer (SCLC) Cells to Sorafenib as well as Inhibiting SCLC Xenograft Growth
- in-vitro, Lung, NA
TrxR↓, eff↑, Dose↝, OS↑, eff↑,
5440- AG,    Astragalus Injection Enhances the Sensitivity of Clinical Cancer Patients to Chemotherapy: A Systematic meta-Analysis
- Review, Var, NA
ChemoSen↑, OS↑,
4402- AgNPs,    Enhancement of Triple-Negative Breast Cancer-Specific Induction of Cell Death by Silver Nanoparticles by Combined Treatment with Proteotoxic Stress Response Inhibitors
- in-vitro, BC, BT549 - in-vitro, BC, MDA-MB-231 - in-vitro, Nor, MCF10
TumCD↑, selectivity↑, *toxicity↝, Dose↝, OS↑,
4394- AgNPs,    Silver nanoparticles provoke apoptosis of Dalton's ascites lymphoma in vivo by mitochondria dependent and independent pathways
- in-vivo, lymphoma, NA
OS↑, TumVol↓, Weight↑, AntiTum↑, Apoptosis↑, mtDam↑,
4362- AgNPs,    Enhancing Colorectal Cancer Radiation Therapy Efficacy using Silver Nanoprisms Decorated with Graphene as Radiosensitizers
- in-vitro, CRC, HCT116 - in-vitro, CRC, HT29 - in-vivo, NA, NA
eff↑, TumCG↓, OS↑, RadioS↑, eff↑, ROS↑, DNAdam↑, eff↝,
333- AgNPs,  HPT,    Enhancement effect of cytotoxicity response of silver nanoparticles combined with thermotherapy on C6 rat glioma cells
- in-vivo, GBM, NA
OS↑,
332- AgNPs,  Rad,    Enhancement of Radiosensitization by Silver Nanoparticles Functionalized with Polyethylene Glycol and Aptamer As1411 for Glioma Irradiation Therapy
- in-vivo, GBM, NA
OS↑,
331- AgNPs,  Rad,    Silver nanoparticles: a novel radiation sensitizer for glioma?
- vitro+vivo, GBM, NA
OS↑,
305- AgNPs,    Activity and pharmacology of homemade silver nanoparticles in refractory metastatic head and neck squamous cell cancer
- Case Report, HNSCC, NA
OS↑, Dose↓, BioAv↝, toxicity↓, Remission↑, other↝, other↝, other↝, Dose↝, BioAv↝,
345- AgNPs,    Antitumor activity of silver nanoparticles in Dalton’s lymphoma ascites tumor model
- vitro+vivo, lymphoma, NA
OS↑, ascitic↓,
5349- Akk,  immuno,    Improved survival in advanced melanoma patients treated with fecal microbiota transplantation using healthy donor stool in combination with anti-PD1: final results of the MIMic phase 1 trial
- Case Report, Melanoma, NA
eff↑, OS↑, eff↑,
287- ALA,  HCA,  Lyco,    Metabolic treatment of cancer: intermediate results of a prospective case series
PSA↓, OS↑,
290- ALA,  HCA,    A combination of alpha lipoic acid and calcium hydroxycitrate is efficient against mouse cancer models: preliminary results
- vitro+vivo, Melanoma, B16-F10
TumCG↓, OS↑,
271- ALA,  VitC,  LDN,    The Long-Term Survival of a Patient With Stage IV Renal Cell Carcinoma Following an Integrative Treatment Approach Including the Intravenous α-Lipoic Acid/Low-Dose Naltrexone Protocol
OS↑, Weight↑, TumVol↓,
274- ALA,  LDN,    Revisiting the ALA/N (alpha-lipoic acid/low-dose naltrexone) protocol for people with metastatic and nonmetastatic pancreatic cancer: a report of 3 new cases
- Human, PC, NA
OS↑,
5325- ALC,    L-Carnitine-supplementation in advanced pancreatic cancer (CARPAN) - a randomized multicentre trial
- Trial, PC, NA
Weight↑, QoL↑, OS↑,
5361- almon,    Abstract CT190: A multicenter, open-label, single-arm, phase II study: The third generation EGFR tyrosine kinase inhibitor almonertinib for pretreated EGFR T790M-positive locally advanced or metastatic non-small cell lung cancer (APOLLO)
- Trial, NSCLC, NA
EGFR↓, OS↑, Dose↝,
5360- almon,  BEV,    Case report: Almonertinib in combination with bevacizumab for leptomeningeal metastases from epidermal growth factor receptor-mutation non-small cell lung cancer: Case series
- Case Report, NSCLC, NA
BBB↑, Dose↝, eff↓, OS↑,
5357- almon,    AENEAS: A Randomized Phase III Trial of Aumolertinib Versus Gefitinib as First-Line Therapy for Locally Advanced or MetastaticNon-Small-Cell Lung Cancer With EGFR Exon 19 Deletion or L858R Mutations
- Trial, NSCLC, NA
EGFR↓, eff↝, OS↑,
4759- antiOx,  Chemo,    Potential Contributions of Antioxidants to Cancer Therapy: Immunomodulation and Radiosensitization
- Review, Var, NA
TumCD↑, TumCG↓, ROS⇅, eff↑, RadioS↑, TumCG↓, OS↑, toxicity∅, toxicity↑,
4760- antiOx,  Chemo,    Impact of antioxidant supplementation on chemotherapeutic efficacy: a systematic review of the evidence from randomized controlled trials
- Review, Var, NA
ChemoSen∅, OS↑, chemoP↑,
4765- antiOx,  Chemo,    Antioxidants as precision weapons in war against cancer chemotherapy induced toxicity – Exploring the armoury of obscurity
- Review, Var, NA
chemoP↑, ChemoSen↑, OS↑, Dose↑, Risk↓, eff↓,
2593- Api,    Apigenin promotes apoptosis of 4T1 cells through PI3K/AKT/Nrf2 pathway and improves tumor immune microenvironment in vivo
- in-vivo, BC, 4T1
TumCP↓, TumCMig↓, TumCI↓, Apoptosis↑, MMP↑, ROS↑, p‑PI3K↓, PI3K↓, Akt↓, NRF2↓, AntiTum↑, OS↑,
1541- Api,  EGCG,    Prospective cohort comparison of flavonoid treatment in patients with resected colorectal cancer to prevent recurrence
- Human, NA, NA
OS↑, Remission↓, Dose∅,
2002- Ash,    Ancient medicine, modern use: Withania somnifera and its potential role in integrative oncology
- Review, Var, NA
antiOx↑, Inflam↓, TumCP↓, OS↑, RadioS↑, radioP↑, chemoP↑,
5372- ATO,    Retinoic Acid and Arsenic Trioxide for Acute Promyelocytic Leukemia
- Trial, APL, NA
Remission↑, OS↑, toxicity↓,
5375- ATO,    Improved Outcome with ATRA-Arsenic Trioxide Compared to ATRA-Chemotherapy in Non-High Risk Acute Promyelocytic Leukemia – Updated Results of the Italian-German APL0406 Trial on the Extended Final Series
- Trial, APL, NA
eff↑, OS↑,
5374- ATO,    A pharmacokinetic and safety study of oral arsenic trioxide in patients with acute promyelocytic leukemia
- Trial, APL, NA
toxicity↓, OS↑,
5453- ATV,    Epidemiologic Analysis Along the Mevalonate Pathway Reveals Improved Cancer Survival in Patients Who Receive Statins Alone and in Combination With Bisphosphonates
- Trial, Var, NA
OS↑, eff↑, other↝,
5449- ATV,    Pleiotropic effects of statins: A focus on cancer
- NA, Var, NA
lipid-P↓, TumCG↓, Apoptosis↑, ChemoSen↑, RAS↓, HMG-CoA↓, HMGCR↓, LDL↓, toxicity↓, Risk↓, P21↑, HDAC↓, Bcl-2↓, BAX↑, BIM↑, Casp↑, cl‑PARP↑, MMP↓, ROS↑, angioG↓, TumMeta↓, PTEN↑, eff↑, OS↑, Remission↑,
4981- ATV,    Crosstalk between Statins and Cancer Prevention and Therapy: An Update
Apoptosis↑, selectivity↑, eff↑, HMG-CoA↓, *cardioP↑, OS↑, IL1β↓, IL6↓, IL8↓, TNF-α↓, TumAuto↑, Histones↝, ac‑H3↑, ac‑H4↑, HDAC↓,
5581- B-Gluc,    Chemo-Immunotherapy Using Lentinan for the Treatment of Gastric Cancer with Liver Metastases
- Human, GC, NA
OS↑,
5568- B-Gluc,  immuno,    Beta-glucans in oncology: revolutionizing treatment with immune power & tumor targeting
- Review, Var, NA
TNF-α↓, IL6↓, NF-kB↓, PD-L1↓, Imm↑, BAX↑, Bcl-2↓, TumCCA↑, angioG↓, VEGF↓, MMPs↓, OS↑, chemoP↑, eff↑, BioAv↑,
5567- B-Gluc,    Trained immunity: A new player in cancer immunotherapy
- Review, Var, NA
Imm↑, ROS↑, Apoptosis↑, OS↑, TumMeta↓, Dose↝,
5566- B-Gluc,    The effects of beta-glucan on human immune and cancer cells
- Review, Var, NA
Imm↑, *BioAv↓, OS↑, ChemoSen↑,
5576- B-Gluc,  Chemo,    Lentinan prolonged survival in patients with gastric cancer receiving S-1-based chemotherapy
- Trial, GC, NA
OS↑, eff↑,
5577- B-Gluc,    Lentinan progress in inflammatory diseases and tumor diseases
- Review, Var, NA - Review, IBD, NA
AntiTum↑, GutMicro↑, *Inflam↓, *TNF-α↓, *NF-kB↓, ChemoSen↑, OS↑, Imm↑, IL6↓, ERK↓, MAPK↓, *antiOx↑, eff↑,
5578- B-Gluc,    A multi-institutional prospective study of lentinan in advanced gastric cancer patients with unresectable and recurrent diseases: effect on prolongation of survival and improvement of quality of life. Kanagawa Lentinan Research Group
- Trial, GC, NA
OS↑, QoL↑,
5580- B-Gluc,    Lentinan, a Shiitake Mushroom β-Glucan, Downregulates the Enhanced PD-L1 Expression Induced by Platinum Compounds in Gastric Cancer Cells
- in-vitro, GC, MKN45
PD-L1↓, MAPK↓, OS↑, AntiTum↑, Imm↑,
5499- Ba,    Anti-cancer effects of baicalein in non-small cell lung cancer in-vitro and in-vivo
- vitro+vivo, Lung, H460 - vitro+vivo, Lung, A549
TumCP↓, Apoptosis↑, F-actin↓, TumVol↓, OS↑, 12LOX↓, VEGF↓, angioG↓,
1376- BBR,  immuno,    Berberine sensitizes immune checkpoint blockade therapy in melanoma by NQO1 inhibition and ROS activation
- in-vivo, Melanoma, NA
OS↑, ROS↑, NQO1↓, ICD↑,
5516- BEV,  immuno,  Chemo,    Targeting vascular normalization: a promising strategy to improve immune–vascular crosstalk in cancer immunotherapy
- Review, Var, NA
OS↑, eff↑,
5595- BEV,  Chemo,    Bevacizumab plus Irinotecan, Fluorouracil, and Leucovorin for Metastatic Colorectal Cancer
- Human, CRC, NA
OS↑,
5623- Bif,    Bifidobacterium breve predicts the efficacy of anti-PD-1 immunotherapy combined with chemotherapy in Chinese NSCLC patients
- Study, NSCLC, NA
GutMicro↑, OS↑, eff↑,
5628- Bif,  immuno,    Bifidobacterium modulation of tumor immunotherapy and its mechanism
- Review, Var, NA
Imm↑, Risk↓, GutMicro↑, AntiTum↑, OS↑, selectivity↑, eff↑,
5692- BJ,    Seed oil of Brucea javanica induces apoptosis through the PI3K/Akt signaling pathway in acute lymphocytic leukemia Jurkat cells
- vitro+vivo, AML, NA
Apoptosis↑, Akt↓, P53↑, FOXO1↑, GSK‐3β↑, TumVol↓, QoL↑, BBB↑, OS↑, Dose↝, MMP↓, ROS↑, XIAP↑, Casp9↑, Casp8↑, Casp3↑, cl‑PARP↑, TumCCA↑,

Showing Research Papers: 1 to 50 of 267
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 267

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

APE1/APEX1↓, 1,   AURKB↓, 1,   CR↑, 3,   DCR↑, 2,   EFS↑, 1,   H3K9↓, 1,   LC↑, 4,   MYCN↑, 1,   NA↑, 1,   OLIG2↓, 1,   ORR↑, 2,   PFS↓, 1,   PFS↑, 2,   PSEN1/PS1↓, 1,   RFS↑, 1,   SUV39H↓, 2,   TCF7/TCF1↓, 1,   TR↑, 1,   TTP↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 5,   Catalase↑, 2,   Copper↓, 1,   CoQ10↑, 1,   cystine↓, 1,   Fenton↑, 1,   Ferroptosis↑, 2,   GPx↓, 1,   GPx↑, 3,   GPx4↓, 2,   GSH↓, 9,   GSH↑, 1,   GSH/GSSG↓, 2,   GSTs↓, 1,   H2O2↑, 4,   HO-1↑, 4,   ICD↑, 1,   Iron↑, 1,   lipid-P↓, 1,   lipid-P↑, 1,   MDA↓, 2,   MDA↑, 1,   NQO1↓, 1,   NRF2↓, 2,   NRF2↑, 5,   NRF2↝, 1,   OXPHOS↑, 2,   mt-OXPHOS↓, 1,   ROS↓, 1,   ROS↑, 59,   ROS⇅, 1,   mt-ROS↑, 1,   SIRT3↑, 1,   SOD↓, 1,   SOD↑, 5,   SOD2↑, 1,   TKT↓, 1,   Trx↓, 1,   TrxR↓, 2,   xCT/SLC7A11↓, 3,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 2,   TfR1/CD71↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 1,   ATP↓, 5,   BCR-ABL↓, 1,   EGF↓, 1,   ETC↓, 1,   Insulin↓, 2,   mitResp↓, 2,   MMP↓, 12,   MMP↑, 2,   MPT↑, 1,   mtDam↑, 7,   OCR↓, 1,   OCR↑, 1,   PGC-1α↑, 3,   PINK1↑, 1,   PleEff↓, 1,   c-Raf↓, 1,   XIAP↓, 1,   XIAP↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX↓, 1,   adiP↑, 1,   ALAT↓, 1,   ALAT↑, 1,   AMPK↑, 5,   ATG7↑, 1,   CAIX/CA9↑, 1,   cMyc↓, 4,   CRM↑, 1,   ECAR↓, 1,   FGF21↓, 1,   glucose↓, 2,   glucose↝, 1,   GlucoseCon↓, 2,   Glycolysis↓, 7,   Histones↝, 1,   HK2?, 1,   HK2↓, 2,   HMG-CoA↓, 2,   KeyT↑, 1,   lactateProd↓, 2,   lactateProd↑, 2,   LDH↓, 3,   LDL↓, 1,   lipoGen↓, 1,   MethCyc↓, 1,   PDH↑, 1,   PDK1 / PDPK1↓, 1,   PDKs↓, 2,   PFK↓, 2,   PKM2↓, 5,   PPARγ↑, 1,   SIRT1↓, 1,   SIRT1↑, 1,   TCA?, 1,   TS↓, 1,   Warburg↓, 2,  

Cell Death(tgid=5) ⓘ

Akt↓, 11,   p‑Akt↓, 3,   p‑Akt↑, 1,   Apoptosis?, 1,   Apoptosis↓, 2,   Apoptosis↑, 31,   Bak↑, 2,   BAX↓, 1,   BAX↑, 8,   Bax:Bcl2↑, 2,   Bcl-2↓, 10,   Bcl-xL↑, 1,   BIM↑, 1,   Casp↑, 3,   Casp3↓, 1,   Casp3↑, 14,   cl‑Casp3↑, 1,   Casp7↑, 1,   Casp8↑, 3,   cl‑Casp8↑, 1,   Casp9↑, 7,   Cyt‑c↑, 6,   Cyt‑c↝, 1,   DR5↑, 1,   FADD↑, 1,   Fas↑, 1,   Ferroptosis↑, 2,   HGF/c-Met↓, 1,   hTERT/TERT↓, 2,   iNOS↓, 1,   iNOS↑, 1,   JNK↑, 3,   MAPK↓, 5,   MAPK↑, 1,   Mcl-1↑, 1,   MOMP↑, 1,   Myc↓, 1,   Necroptosis↑, 1,   necrosis↑, 3,   p27/CDKN1B↑, 2,   p38↑, 2,   p‑p38↑, 1,   Pyro↑, 1,   RIP1↑, 1,   survivin↓, 1,   TumCD↑, 8,  

Kinase & Signal Transduction(tgid=6) ⓘ

EF-1α↓, 1,   p‑p70S6↓, 1,   SOX9↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

BowelM↑, 2,   ChrMod↑, 1,   cJun↑, 1,   H3↑, 1,   ac‑H3↑, 1,   H4↑, 1,   ac‑H4↑, 1,   HATs↑, 1,   KISS1↑, 1,   other?, 1,   other↓, 1,   other↑, 2,   other⇅, 1,   other↝, 14,   OV6↓, 1,   p‑pRB↓, 1,   SD↑, 1,   tumCV↓, 7,   tumCV↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

cl‑CHOP/DDIT3↑, 1,   ER Stress↑, 3,   GRP78/BiP↑, 1,   HSP70/HSPA5↑, 2,   HSPs↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   LC3B↑, 1,   LC3I↑, 1,   LC3II↑, 2,   LC3s↓, 1,   MitoP↑, 1,   p62↓, 1,   p62↑, 2,   TumAuto↓, 1,   TumAuto↑, 8,  

DNA Damage & Repair(tgid=10) ⓘ

ATR↑, 1,   BRCA1↑, 1,   BRCA2↑, 1,   CHK1↑, 1,   DNAdam↑, 11,   DNArepair↓, 2,   DNArepair↑, 2,   P53?, 1,   P53↑, 13,   p‑P53↑, 1,   PARP↑, 1,   cl‑PARP↑, 7,   PCNA↓, 5,   TP53↓, 1,   γH2AX↑, 2,   p‑γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CDK2↓, 4,   CDK4↓, 6,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 9,   E2Fs↓, 1,   P21?, 1,   P21↓, 1,   P21↑, 9,   p‑RB1↓, 1,   TumCCA↑, 24,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 1,   AXIN1↑, 2,   CD133↓, 3,   CD44↓, 1,   CSCs↓, 5,   Diff↑, 1,   EMT↓, 10,   EMT↝, 1,   EP2↓, 1,   EpCAM↓, 1,   ERK↓, 5,   ERK↑, 1,   ERK5↓, 1,   FOXM1↓, 1,   FOXO1↑, 1,   FOXO3↓, 1,   GATA3↓, 1,   GH↓, 1,   Gli1↓, 4,   GSK‐3β↑, 1,   p‑GSK‐3β↓, 1,   HDAC↓, 7,   HDAC8↓, 1,   HH↓, 8,   HMGCR↓, 1,   IGF-1↓, 8,   IGF-1R↓, 1,   IGFBP1↑, 1,   IGFBP3↑, 1,   miR-34a↑, 1,   mTOR↓, 11,   mTOR↑, 1,   mTORC1↓, 2,   Nanog↓, 1,   Nestin↓, 1,   NOTCH↓, 1,   NOTCH1↓, 2,   NOTCH3↓, 1,   OCT4↓, 1,   P70S6K↓, 1,   PI3K↓, 11,   PI3K↑, 1,   p‑PI3K↓, 1,   PTEN↓, 1,   PTEN↑, 2,   RAS↓, 2,   Shh↓, 1,   Smo↓, 1,   SOX2↓, 1,   STAT3↓, 6,   p‑STAT3↑, 1,   TK1↓, 1,   TOP2↑, 1,   TRPM7↓, 1,   TumCG↓, 52,   TumCG↑, 1,   TumCG⇅, 1,   TumCG↝, 1,   VGSC↑, 1,   Wnt↓, 6,  

Migration(tgid=13) ⓘ

5LO↓, 1,   AP-1↓, 1,   BACH1↑, 1,   Ca+2↑, 3,   CD31/PECAM-1↓, 1,   CDKN1C/p57↑, 1,   CEA↓, 1,   CLDN1↓, 1,   Cofilin↓, 1,   CXCL12↓, 1,   E-cadherin↓, 2,   E-cadherin↑, 8,   F-actin↓, 2,   fascin↓, 1,   GLI2↓, 1,   GLI3↑, 1,   Ki-67↓, 7,   KRAS↓, 1,   MALAT1↓, 1,   MMP1↓, 1,   MMP13↓, 1,   MMP2↓, 5,   MMP3↓, 1,   MMP7↓, 1,   MMP9↓, 7,   MMPs↓, 4,   N-cadherin↓, 6,   PKCδ↓, 1,   Rho↓, 2,   RIP3↑, 1,   ROCK1↓, 1,   Slug↓, 1,   Snail↓, 1,   SOX4↓, 1,   TGF-β↓, 1,   TIMP1↓, 1,   TIMP1↑, 1,   TIMP2↑, 1,   TIMP3↑, 1,   Treg lymp↓, 2,   TSP-1↑, 1,   TumCI↓, 11,   TumCMig↓, 13,   TumCP↓, 27,   TumMeta↓, 16,   TumMeta↑, 2,   Twist↓, 1,   Vim↓, 4,   Zeb1↓, 2,   ZEB2↓, 1,   α-tubulin↓, 1,   β-catenin/ZEB1↓, 6,   β-catenin/ZEB1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 16,   EGFR↓, 5,   eNOS↑, 1,   EPR↑, 2,   Hif1a↓, 10,   Hif1a↝, 1,   Hypoxia↓, 2,   LymphAG↓, 1,   NO↓, 1,   NO↑, 1,   PDGFR-BB↓, 1,   TAMS↓, 1,   VEGF↓, 16,   VEGF↑, 1,   VEGFR2/KDR/Flk1↓, 4,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 4,   CellMemb↑, 1,   GLUT1↑, 1,   GLUT3↑, 1,   P-gp/ABCB1↓, 4,   SVCT-2∅, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↓, 1,   CD4+↑, 5,   COX2/PTGS2↓, 10,   CRP↓, 1,   CXCc↓, 1,   CXCL9↓, 1,   DCells↓, 1,   DCells↑, 2,   FOXP3↓, 1,   GM-CSF↓, 1,   HMGB1↓, 2,   IFN-γ↓, 2,   IFN-γ↑, 2,   IKKα↓, 1,   IL1↑, 1,   IL10↓, 2,   IL10↑, 2,   IL12↑, 2,   IL17↑, 1,   IL18↑, 1,   IL1β↓, 4,   IL1β↑, 1,   IL2↑, 2,   IL4↓, 1,   IL4↑, 1,   IL6↓, 12,   IL6↑, 1,   IL8↓, 3,   IL8↑, 1,   Imm↑, 13,   Imm↝, 2,   Inflam↓, 9,   Macrophages↑, 1,   NF-kB↓, 13,   NK cell↑, 6,   p65↓, 2,   p65↑, 1,   PD-L1↓, 3,   PDT+↓, 1,   PGE1↓, 1,   PGE2↓, 4,   PSA↓, 4,   PSA∅, 1,   Resistin↓, 1,   T-Cell↑, 2,   Th1 response↑, 1,   TLR4↓, 1,   TNF-α↓, 12,   TNF-α↑, 3,  

Cellular Microenvironment(tgid=17) ⓘ

pH↑, 1,   pH↝, 2,   e-pH↑, 3,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 1,   ER(estro)↓, 1,   EstroRS/ERS↑, 1,   GR↑, 1,   Irisin↓, 1,   Leptin↓, 2,   RANKL↓, 1,   testos∅, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2,   BioAv↑, 9,   BioAv↝, 3,   ChemoSen↓, 1,   ChemoSen↑, 40,   ChemoSen∅, 1,   Dose↓, 3,   Dose↑, 9,   Dose↝, 69,   Dose∅, 15,   eff↓, 11,   eff↑, 88,   eff⇅, 1,   eff↝, 12,   Half-Life↓, 2,   Half-Life↑, 2,   Half-Life↝, 3,   Half-Life∅, 1,   MDR1↓, 1,   RadioS↑, 18,   selectivity↑, 28,   TET2↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 6,   ALAT↓, 1,   ALAT↑, 1,   AR↓, 1,   ascitic↓, 1,   AST↓, 1,   AST↑, 1,   BG↓, 1,   BloodF↑, 2,   BMD↑, 5,   BRCA1↑, 1,   CA125↓, 2,   CA19-9↓, 1,   CEA↓, 1,   CRP↓, 1,   CYFRA21-1↓, 1,   EGFR↓, 5,   EstroRS/ERS↑, 1,   Ferritin↓, 2,   FOXM1↓, 1,   GutMicro↑, 5,   hTERT/TERT↓, 2,   IL6↓, 12,   IL6↑, 1,   Ki-67↓, 7,   KRAS↓, 1,   LDH↓, 3,   Myc↓, 1,   PD-L1↓, 3,   PSA↓, 4,   PSA∅, 1,   TP53↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 2,   AntiCan↓, 1,   AntiCan↑, 9,   antiNeop↑, 3,   AntiTum↓, 1,   AntiTum↑, 15,   Appetite↑, 1,   breath↑, 1,   cachexia↓, 1,   cardioP↑, 4,   chemoP↑, 10,   chemoPv↑, 1,   ChemoSideEff↓, 3,   cognitive↑, 2,   fatigue↓, 3,   hepatoP↑, 3,   neuroP↓, 1,   neuroP↑, 4,   OS↓, 1,   OS↑, 269,   OS∅, 1,   Pain↓, 5,   QoL↑, 22,   QoL∅, 1,   radioP↑, 10,   Remission↓, 1,   Remission↑, 9,   Risk↓, 13,   Risk↑, 1,   Risk↝, 1,   Risk∅, 1,   Sleep↑, 1,   Strength↑, 2,   toxicity↓, 20,   toxicity↑, 3,   toxicity↝, 6,   toxicity∅, 4,   TumVol↓, 23,   TumVol↑, 2,   TumW↓, 3,   Weight↓, 2,   Weight↑, 9,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 1,   CD8+↑, 6,  
Total Targets: 519

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 9,   Catalase↑, 6,   GPx↑, 4,   GSH↑, 5,   GSR↑, 2,   GSTs↑, 1,   HDL↑, 1,   HO-1↑, 1,   lipid-P↓, 3,   MDA↓, 1,   NRF2↓, 2,   NRF2↑, 2,   ROS↓, 13,   selenoP↑, 2,   SOD↑, 6,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 2,   AMPK↑, 2,   glucose↓, 1,   LDH↓, 2,   PPARα↝, 1,   PPARγ↑, 1,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 1,   Casp↓, 1,   Casp3↓, 2,   Casp9↓, 1,   Cyt‑c↓, 1,   JNK↓, 1,   MAPK↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 2,   other↓, 1,   TREM-1↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,   DNArepair↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

GSK‐3β↓, 1,   PTEN↑, 1,  

Migration(tgid=13) ⓘ

Ca+2↓, 1,   TRPC1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   Hif1a↓, 1,   Hif1a↑, 1,   NO↓, 2,   VEGF↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 1,   CRP↓, 1,   GM-CSF↑, 1,   IL6↓, 2,   Imm↑, 1,   Inflam↓, 8,   IP-10/CXCL-10↑, 1,   NF-kB↓, 5,   TLR4↓, 1,   TNF-α↓, 3,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,   AChE↓, 3,   BDNF↑, 1,   EndoR↑, 1,   monoA↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

testos↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2,   BioAv↑, 3,   BioEnh↑, 1,   Dose⇅, 1,   Dose↝, 1,   eff↑, 4,   Half-Life↝, 1,   P450↓, 3,   selectivity↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   ALP↓, 2,   AST↓, 2,   BP↓, 1,   CRP↓, 1,   GutMicro↑, 2,   IL6↓, 2,   LDH↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiDiabetic↑, 2,   cardioP↑, 5,   cognitive↑, 1,   hepatoP↑, 2,   memory↑, 2,   motorD↑, 1,   neuroP↑, 5,   Pain↓, 1,   Risk↓, 1,   toxicity?, 1,   toxicity↓, 7,   toxicity↝, 4,   toxicity∅, 5,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 3,   Bacteria↓, 1,  
Total Targets: 94

Scientific Paper Hit Count for: OS, overall survival
16 Magnetic Fields
14 Chemotherapy
13 Vitamin C (Ascorbic Acid)
12 Radiotherapy/Radiation
12 Magnetic Field Rotating
8 Silver-NanoParticles
8 Hyperthermia
8 immunotherapy
8 beta-glucans
8 Hydrogen Gas
8 Selenium
7 Dichloroacetate
7 itraconazole
6 Alpha-Lipoic-Acid
6 capecitabine
6 diet Plant based
5 cetuximab
5 diet FMD Fasting Mimicking Diet
5 diet Methionine-Restricted Diet
5 Bicarbonate(Sodium)
4 HydroxyCitric Acid
4 Melatonin
4 Phenylbutyrate
4 Phenethyl isothiocyanate
4 Ramucirumab (CYRAMZA)
3 3-bromopyruvate
3 Lycopene
3 almonertinib
3 Bevacizumab (brand Avastin)
3 Anti-oxidants
3 Arsenic trioxide
3 Atorvastatin
3 Exercise
3 Fucoidan
3 Gemcitabine (Gemzar)
3 Inositol
3 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
3 iodine
3 nivolumab
3 metronomic chemo
3 Sulfasalazine
3 Shikonin
3 Selenite (Sodium)
2 low dose naltrexone
2 Apigenin (mainly Parsley)
2 EGCG (Epigallocatechin Gallate)
2 Bifidobacterium
2 Docetaxel
2 Carvacrol
2 Chlorogenic acid
2 chaetocin
2 Choline
2 Citric Acid
2 Curcumin
2 Quercetin
2 Oxygen, Hyperbaric
2 Sulforaphane (mainly Broccoli)
2 diet Short Term Fasting
2 Orlistat
2 hydroxychloroquine
2 Honokiol
2 imatinib
2 isoflavones
2 Juglone
2 Lapatinib
2 Lactoferrin/Talactoferrin
2 ipilimumab
2 Metformin
2 Propolis -bee glue
2 Piperine
2 doxorubicin
2 EMF
2 VitK3,menadione
1 2-DeoxyGlucose
1 Auranofin
1 Astragalus
1 Akkermansia
1 Acetyl-l-carnitine
1 Ashwagandha(Withaferin A)
1 Baicalein
1 Berberine
1 Brucea javanica
1 Boron
1 Caffeine
1 Caffeic Acid Phenethyl Ester (CAPE)
1 Sorafenib (brand name Nexavar)
1 Celastrol
1 chitosan
1 Chrysin
1 Coenzyme Q10
1 Artemisinin
1 Dasatinib/Phyrago
1 salinomycin
1 Deguelin
1 diet Fermented Foods
1 Bortezomib
1 diet Ketogenic
1 D-limonene
1 Disulfiram
1 Echinacea
1 Emodin
1 Electrical Pulses
1 Folic Acid, Vit B9
1 Formononetin
1 Flaxseed/Linseed
1 Garcinol
1 Geraniol
1 5-fluorouracil
1 Ginkgolide B
1 Gossypol/AT-101
1 Paclitaxel/Taxol
1 Isoliquiritigenin
1 Trastuzumab
1 Licochalcone A
1 Lutein
1 Magnolol
1 mebendazole
1 Magnesium
1 Mistletoe/Viscum album Extracts
1 Helleborus niger extracts – Christmas Rose
1 Naringin
1 Noscapine
1 Piperlongumine
1 Silymarin (Milk Thistle) silibinin
1 Iron
1 Salvia miltiorrhiza
1 Spermidine
1 tetrathiomolybdate
1 Tumor Treating Fields
1 Turmerones
1 Urolithin
1 Vitamin K2
1 Xylitol
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:229  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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