IGF-1 Cancer Research Results

IGF-1, insulin-like growth factor-1: Click to Expand ⟱
Source:
Type:
Higher blood levels of IGF-1, a growth factor, are linked to increased risk of several types of cancer, including thyroid, melanoma and myeloma. IGF-1 is what some call "a growth-promoter" because it has been shown to promote the growth of cancer cells.
The IGF-1 signaling pathway promotes cancer progression; its downregulation is associated with lowered risk.
Scientific Papers found: Click to Expand⟱
1853- dietFMD,    Impact of Fasting on Patients With Cancer: An Integrative Review
- Review, Var, NA
*toxicity∅, QoL∅, eff↑, eff↝, ChemoSideEff↓, TumCG↓, Dose↑, toxicity↝, eff↑, IGF-1↑, *OXPHOS↑, BG↓, Insulin↓, RadioS↑,
6266- DL,    Human breast tissue disposition and bioactivity of limonene in women with early-stage breast cancer
- Trial, BC, NA
chemoPv↑, cycD1/CCND1↓, IGF-1↑, TumCCA↑, TumCP↓,
5062- Ex,    The Influence of Exercise on the Insulin-like Growth Factor Axis in Oncology: Physiological Basis, Current, and Future Perspectives
- Review, Var, NA
IGF-1↑,

Showing Research Papers: 1 to 3 of 3

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 3

Pathway results for Effect on Cancer / Diseased Cells:


Mitochondria & Bioenergetics(tgid=3) ⓘ

Insulin↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

IGF-1↑, 3,   TumCG↓, 1,  

Migration(tgid=13) ⓘ

TumCP↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↑, 1,   eff↑, 2,   eff↝, 1,   RadioS↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

BG↓, 1,  

Functional Outcomes(tgid=23) ⓘ

chemoPv↑, 1,   ChemoSideEff↓, 1,   QoL∅, 1,   toxicity↝, 1,  
Total Targets: 15

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

OXPHOS↑, 1,  

Functional Outcomes(tgid=23) ⓘ

toxicity∅, 1,  
Total Targets: 2

Scientific Paper Hit Count for: IGF-1, insulin-like growth factor-1
1 diet FMD Fasting Mimicking Diet
1 D-limonene
1 Exercise
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:415  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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