miR-126 Cancer Research Results

miR-126, miR-126: Click to Expand ⟱
Source:
Type: tumour-suppressor miRNA
miR-126 is involved in the regulation of angiogenesis, which is the process of forming new blood vessels.
miR-126 is downregulated in many types of cancer, including breast, lung, colon, and pancreatic cancer.
The downregulation of miR-126 has been associated with poor prognosis and increased metastasis in cancer patients.
Scientific Papers found: Click to Expand⟱
736- Bor,    Evaluation of Boric Acid Treatment on microRNA-127-5p and Metastasis Genes Orchestration of Breast Cancer Stem Cells
- in-vitro, BC, MCF7
miR-126↑, COL1A1↓, Vim↓, Zeb1↑, CDH1↑, ITGB1↑, ITGA5↑, LAMA5↑, Snail↑, miR-127-5p↑,
5846- CAP,    Capsaicin Alters the Expression of Genetic and Epigenetic Molecules In Hepatocellular Carcinoma Cell
- in-vitro, HCC, HepG2
Dose↝, miR-126↑, Ki-67↓, PI3K↓, mTOR↓, Akt↑, eff↑, Casp3↑,
4707- CUR,    The Potential Role of Curcumin as a Regulator of microRNA in Colorectal Cancer: A Systematic Review
- Review, Var, NA
miR-497↑, miR-200c↑, miR-409-3p↑, miR-34a↑, miR-126↑, miR-145↑, miR-206↑, miR-491↑, miR-141↑, miR-429↑, miR-101↑, miR-15↑, miR-21↓, miR-155↓, miR-221↓, miR-222↓, miR-17↓, miR-130a↓, miR-27a-3p↓, miR-20↓,
8281- LE,    A Licorice Roots Extract Induces Apoptosis and Cell Cycle Arrest and Improves Metabolism via Regulating MiRNAs in Liver Cancer Cells
- in-vitro, Liver, NA
Apoptosis↑, TumCCA↑, Let-7↑, miR-34b-5p↑, miR-122-5p↑, miR-126↑, miR-195↑, miR-199↑, miR-206↑, miR-326-5p↑, Hif1a↓, PI3K↓, cMyc↓, AMPK↑, P53↑, Glycolysis↓, HK2↓, LDHA↓, PKM2↓, PPP↓, G6PD↓, GlutaM↓, GLS↓, miR-21↑, miR-221↑, miR-222↑,

Showing Research Papers: 1 to 4 of 4

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 4

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

miR-122-5p↑, 1,   miR-195↑, 1,   miR-199↑, 1,   miR-326-5p↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AMPK↑, 1,   cMyc↓, 1,   G6PD↓, 1,   GLS↓, 1,   GlutaM↓, 1,   Glycolysis↓, 1,   HK2↓, 1,   LDHA↓, 1,   PKM2↓, 1,   PPP↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↑, 1,   Apoptosis↑, 1,   Casp3↑, 1,   miR-127-5p↑, 1,   miR-497↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

miR-145↑, 1,   miR-21↓, 1,   miR-21↑, 1,   miR-27a-3p↓, 1,   miR-409-3p↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

P53↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Let-7↑, 1,   miR-101↑, 1,   miR-34a↑, 1,   miR-429↑, 1,   mTOR↓, 1,   PI3K↓, 2,  

Migration(tgid=13) ⓘ

CDH1↑, 1,   COL1A1↓, 1,   ITGA5↑, 1,   ITGB1↑, 1,   Ki-67↓, 1,   LAMA5↑, 1,   miR-130a↓, 1,   miR-141↑, 1,   miR-155↓, 1,   miR-20↓, 1,   miR-200c↑, 1,   miR-206↑, 2,   miR-221↓, 1,   miR-221↑, 1,   miR-222↓, 1,   miR-222↑, 1,   miR-491↑, 1,   Snail↑, 1,   Vim↓, 1,   Zeb1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

Hif1a↓, 1,   miR-126↑, 4,   miR-15↑, 1,   miR-17↓, 1,   miR-34b-5p↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 1,   eff↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

Ki-67↓, 1,  
Total Targets: 60

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: miR-126, miR-126
1 Boron
1 Capsaicin
1 Curcumin
1 Licorice
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:766  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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