AntiCan Cancer Research Results

AntiCan, Anticancer Effect: Click to Expand ⟱
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Type: general indicator
Anticancer Effect


Scientific Papers found: Click to Expand⟱
4384- ,    Silver nanoparticles: synthesis, properties, and therapeutic applications
- Review, Var, NA
AntiCan↑, RadioS↑, CellMemb↑, ROS↑, DNAdam↑, PhotoS↑, eff↑,
4442- ,    Anticancer and Hepatoprotective Role of Selenium Nanoparticles against
- in-vivo, Liver, HepG2 - NA, Nor, NA
*hepatoP↑, AntiCan↑,
6467- 1,8-Cin,    Evaluation of in vitro anticancer activity of 1,8-Cineole-containing n-hexane extract of Callistemon citrinus (Curtis) Skeels plant and its apoptotic potential
- in-vitro, Melanoma, A431 - in-vitro, OS, MG63 - in-vitro, Nor, HaCaT
TumCP↓, selectivity↑, AntiCan↑, TumCD↑, Apoptosis↑, Dose↝, ROS↑,
5275- 3BP,    3-Bromopyruvate (3BP) a fast acting, promising, powerful, specific, and effective "small molecule" anti-cancer agent taken from labside to bedside: Introduction to a special issue
- Review, Var, NA
AntiCan↑, HK2↓, OCR↓,
5273- 3BP,    The promising anticancer drug 3-bromopyruvate is metabolized through glutathione conjugation which affects chemoresistance and clinical practice: An evidence-based view
- Review, Var, NA
AntiCan↑, ROS↑, angioG↓, CSCs↓, Warburg↓, GSH↓, Thiols↓,
4774- 5-FU,  TQ,  CoQ10,    Exploring potential additive effects of 5-fluorouracil, thymoquinone, and coenzyme Q10 triple therapy on colon cancer cells in relation to glycolysis and redox status modulation
- in-vitro, CRC, NA
AntiCan↑, TumCCA↑, Apoptosis↑, eff↑, Bcl-2↓, survivin↓, P21↑, p27/CDKN1B↑, BAX↑, Cyt‑c↑, Casp3↑, PI3K↓, Akt↓, mTOR↓, Hif1a↓, PTEN↑, AMPKα↑, PDH↑, LDHA↓, antiOx↓, ROS↑, AntiCan↑,
5472- AF,    Auranofin induces apoptosis and necrosis in HeLa cells via oxidative stress and glutathione depletion
- in-vitro, Cerv, HeLa
TrxR↓, AntiCan↑, TumCG↓, Apoptosis↑, necrosis↑, cl‑PARP↑, MMP↓, ROS↑, GSH↓, eff↓,
5434- AG,    Recent Advances in the Mechanisms and Applications of Astragalus Polysaccharides in Liver Cancer Treatment: An Overview
- Review, Liver, NA
AntiCan↑, Apoptosis↑, TumCP↓, EMT↓, Imm↑, ChemoSen↑, BioAv↓, TumCG↓, IL2↑, IL12↑, TNF-α↑, P-gp/ABCB1↓, MDR1↓, QoL↑, Casp↑, DNAdam↑, Bcl-2↓, BAX↑, MMP↓, Cyt‑c↑, NOTCH1↓, GSK‐3β↓, TumCCA↑, GSH↓, ROS↑, lipid-P↑, c-Iron↑, GPx4↓, ACSL4↑, Ferroptosis↑, Wnt↓, β-catenin/ZEB1↓, cycD1/CCND1↓, Akt↓, PI3K↓, mTOR↓, CXCR4↓, Vim↓, PD-L1↓, eff↑, eff↑, ChemoSen↑, ChemoSen↑, chemoP↑,
5976- AgNPs,    Review on Harnessing Silver Nanoparticles for Therapeutic Innovations: A Comprehensive Review on Medical Applications, Safety, and Future Directions
- Review, Vit, NA
*Bacteria↓, AntiCan↑, *Inflam↓, *Wound Healing↑, eff↑, ChemoSen↑, EGFR↓, ROS↑, P53↑, BAX↑, Casp3↑, toxicity↝,
5978- AgNPs,    Biological synthesis of silver nanoparticles and their medical applications
- Review, Var, NA
Wound Healing↑, AntiCan↑, other↑, MPT↑, ROS↑, other↑, DNAdam↑,
4403- AgNPs,    Silver Nanoparticles Decorated UiO-66-NH2 Metal-Organic Framework for Combination Therapy in Cancer Treatment
- in-vitro, GBM, U251 - in-vitro, GBM, U87MG - in-vitro, GBM, GL26 - in-vitro, Cerv, HeLa - in-vitro, CRC, RKO
AntiCan↑, eff↑, EPR↑, selectivity↑, ROS↑, Casp↑, Apoptosis↑, DNAdam↑, tumCV↓, eff↑,
4396- AgNPs,    Identification of possible reductants in the aqueous leaf extract of mangrove plant Rhizophora apiculata for the fabrication and cytotoxicity of silver nanoparticles against human osteosarcoma MG-63 cells
- in-vitro, OS, MG63
AntiCan↑, tumCV↓,
4389- AgNPs,    Graphene Oxide-Silver Nanocomposite Enhances Cytotoxic and Apoptotic Potential of Salinomycin in Human Ovarian Cancer Stem Cells (OvCSCs): A Novel Approach for Cancer Therapy
- in-vitro, Ovarian, NA
tumCV↓, ROS↑, LDH↓, MMP↑, CSCs↓, AntiCan↑,
4422- AgNPs,    Bioengineering of Piper longum L. extract mediated silver nanoparticles and their potential biomedical applications
- in-vitro, Cerv, HeLa
AntiCan↑, selectivity↑,
4412- AgNPs,    Biosynthesis and characterization of silver nanoparticles from Asplenium dalhousiae and their potential biological properties
- in-vitro, CRC, HCT116 - in-vitro, Melanoma, A2780S
Bacteria↓, antiOx↑, AntiCan↑, eff↑,
4411- AgNPs,    Eco-friendly synthesis of silver nanoparticles using Anemone coronaria bulb extract and their potent anticancer and antibacterial activities
- in-vitro, Lung, A549 - in-vitro, PC, MIA PaCa-2 - in-vitro, Pca, PC3 - in-vitro, Nor, HEK293
AntiCan↑, selectivity↑, Apoptosis↑, TumCCA↑, Bacteria↓, tumCV↓, selectivity↑, Apoptosis↑, TumCCA↑,
4410- AgNPs,    Green-synthesized silver nanoparticles: a sustainable nanoplatform for targeted colon cancer therapy
- Review, Colon, NA
AntiCan↑, ROS↑, mtDam↑, tumCV↓, selectivity↑,
4431- AgNPs,  doxoR,    Oxidative Stress-Induced Silver Nano-Carriers for Chemotherapy
- in-vitro, BC, 4T1 - in-vivo, BC, 4T1 - in-vitro, Nor, 3T3
AntiCan↑, ROS↑, TumVol↓, EPR↑, selectivity↑, ChemoSen↑,
4552- AgNPs,  ART/DHA,    Green synthesis of silver nanoparticles using Artemisia turcomanica leaf extract and the study of anti-cancer effect and apoptosis induction on gastric cancer cell line (AGS)
- in-vitro, GC, AGS
AntiCan↑, Apoptosis↑, eff↑,
4561- AgNPs,  VitC,    Cellular Effects Nanosilver on Cancer and Non-cancer Cells: Potential Environmental and Human Health Impacts
- in-vitro, CRC, HCT116 - in-vitro, Nor, HEK293
NRF2↑, TumCCA↑, ROS↑, selectivity↑, *AntiViral↑, *toxicity↝, ETC↓, MMP↓, DNAdam↑, Apoptosis↑, lipid-P↑, other↝, UPR↑, *GRP78/BiP↑, *p‑PERK↑, *cl‑eIF2α↑, *CHOP/DDIT3↑, *JNK↑, Hif1a↓, AntiCan↑, *toxicity↓, eff↑,
4560- AgNPs,    Exploiting antidiabetic activity of silver nanoparticles synthesized using Punica granatum leaves and anticancer potential against human liver cancer cells (HepG2)
- in-vitro, Liver, HepG2 - in-vitro, Diabetic, NA
AntiCan↑, Dose↝, *antiOx↑, *AntiDiabetic↑, *Bacteria↓,
4555- AgNPs,    Silver nanoparticles from Dendropanax morbifera Léveille inhibit cell migration, induce apoptosis, and increase generation of reactive oxygen species in A549 lung cancer cells
- in-vitro, Lung, A549 - in-vitro, Liver, HepG2
*Bacteria↓, tumCV↓, selectivity↑, ROS↑, Apoptosis↑, TumCMig↓, AntiCan↑,
4539- AgNPs,  VitC,  Citrate,    Investigating the Anti-cancer Potential of Silver Nanoparticles Synthesized by Chemical Reduction of AgNO3 Using Trisodium Citrate and Ascorbic Acid
- in-vitro, Nor, L929 - in-vitro, Ovarian, SKOV3
AntiCan↑,
4548- AgNPs,  Chit,    Synergistic combination of antioxidants, silver nanoparticles and chitosan in a nanoparticle based formulation: Characterization and cytotoxic effect on MCF-7 breast cancer cell lines
- in-vitro, BC, MCF7
AntiCan↑, EPR↑, pH↝,
4542- AgNPs,    Silver Nanoparticles (AgNPs): Comprehensive Insights into Bio/Synthesis, Key Influencing Factors, Multifaceted Applications, and Toxicity─A 2024 Update
- Review, NA, NA
AntiCan↑, DNAdam↑, ATP↓, Apoptosis↑, ROS↓, TumCCA↑, *Bacteria↓, *BMD↑,
4584- AgNPs,    Silver Nanoparticles Synthesized Using Carica papaya Leaf Extract (AgNPs-PLE) Causes Cell Cycle Arrest and Apoptosis in Human Prostate (DU145) Cancer Cells
- in-vitro, Pca, DU145
selectivity↑, ROS↑, BAX↑, cl‑Casp3↑, p‑PARP↑, TumCCA↑, cycD1/CCND1↓, p27/CDKN1B↑, P21↑, AntiCan↑,
5356- AL,    Therapeutic role of allicin in gastrointestinal cancers: mechanisms and safety aspects
- Review, GC, NA
Apoptosis↑, TumCP↓, MAPK↓, PI3K↓, Akt↓, NF-kB↓, AntiCan↑, ChemoSen↑, TumCCA↑, Apoptosis↑, BioAv↑, selectivity↑, TGF-β↓, ROS↑, DNAdam↑, p‑P53↑, P21↑, cycD1/CCND1↓, cycE/CCNE↓, CDK4↓, CDK6↓, MMP↓, NF-kB↑, BAX↑, Bcl-2↓, ER Stress↑, Casp↑, AIF↑, Fas↑, Casp8↑, Cyt‑c↑, cl‑PARP↑, Ca+2↑, *NRF2↑, *chemoP↑, *GutMicro↑, CycB/CCNB1↑, H2S↑, HIF-1↓, RadioS↑,
5354- AL,    Therapeutic Potential of Allicin-Rich Garlic Preparations: Emphasis on Clinical Evidence toward Upcoming Drugs Formulation
- Review, Var, NA
*LDL↓, *antiOx↑, AntiCan↑, *cardioP↑, *BP↓, *Weight↓, NK cell↑, *AntiDiabetic↑, *GSH↑,
2646- AL,    Anti-Cancer Potential of Homemade Fresh Garlic Extract Is Related to Increased Endoplasmic Reticulum Stress
- in-vitro, Pca, DU145 - in-vitro, Melanoma, RPMI-8226
AntiCan↑, eff↓, ChemoSen↑, ER Stress↑, tumCV↓, DNAdam↑, GSH∅, HSP70/HSPA5↓, UPR↑, β-catenin/ZEB1↓, ROS↑, HO-2↑, SIRT1↑, GlucoseCon∅, lactateProd∅, chemoP↑,
2660- AL,    Allicin: A review of its important pharmacological activities
- Review, AD, NA - Review, Var, NA - Review, Park, NA - Review, Stroke, NA
*Inflam↓, AntiCan↑, *antiOx↑, *cardioP↑, *hepatoP↑, *BBB↑, *Half-Life↝, *H2S↑, *BP↓, *neuroP↑, *cognitive↑, *neuroP↑, *ROS↓, *GutMicro↑, *LDH↓, *ROS↓, *lipid-P↓, *antiOx↑, *other↑, *PI3K↓, *Akt↓, *NF-kB↓, *NO↓, *iNOS↓, *PGE2↓, *COX2/PTGS2↓, *IL6↓, *TNF-α↓, *MPO↓, *eff↑, *NRF2↑, *Keap1↓, *TBARS↓, *creat↓, *LDH↓, *AST↓, *ALAT↓, *MDA↓, *SOD↑, *GSH↑, *GSTs↑, *memory↑, chemoP↑, IL8↓, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Casp12↑, p38↑, Fas↑, P53↑, P21↑, CHK1↓, CycB/CCNB1↓, GSH↓, ROS↑, TumCCA↑, Hif1a↓, Bcl-2↓, VEGF↓, TumCMig↓, STAT3↓, VEGFR2/KDR/Flk1↓, p‑FAK↓,
2666- AL,    Targeting the Interplay of Autophagy and ROS for Cancer Therapy: An Updated Overview on Phytochemicals
- Review, Var, NA
Inflam↓, AntiCan↑, ROS↑, MAPK↑, JNK↑, TumAuto↑, other↑, Dose↝, MALAT1↓, Wnt↓, β-catenin/ZEB1↓,
2667- AL,    Allicin in Digestive System Cancer: From Biological Effects to Clinical Treatment
- Review, GC, NA
AntiCan↑, ChemoSen↑, angioG↓, chemoP↑, *GutMicro↑, *antiOx↑, other↝, GSH↓, Thiols↓, *ROS↓, *hepatoP↑, *Inflam↓, *NF-kB↓,
3443- ALA,    Molecular and Therapeutic Insights of Alpha-Lipoic Acid as a Potential Molecule for Disease Prevention
- Review, Var, NA - Review, AD, NA
*antiOx↑, *ROS↓, *IronCh↑, *cognitive↑, *cardioP↓, AntiCan↑, *neuroP↑, *Inflam↓, *BioAv↓, *AntiAge↑, *Half-Life↓, *BioAv↝, other↝, EGFR↓, Akt↓, ROS↓, TumCCA↑, p27/CDKN1B↑, PDH↑, Glycolysis↓, ROS↑, *eff↑, *memory↑, *motorD↑, *GutMicro↑,
6393- ANE,    Anethole in cancer therapy: Mechanisms, synergistic potential, and clinical challenges
- Review, Var, NA
AntiCan↑, Apoptosis↑, TumCCA↑, TumCP↓, angioG↓, NF-kB↓, PI3K↓, Akt↓, mTOR↓, Casp↓, ChemoSen↑,
6397- ANE,  Cisplatin,    Synergistic Effect of Anethole and Platinum Drug Cisplatin against Oral Cancer Cell Growth and Migration by Inhibiting MAPKase, Beta-Catenin, and NF-κB Pathways
- in-vitro, SCC, Ca9-22
AntiCan↑, ChemoSen↑, TumCP↓, MMP↓, ROS↑, MAPK↓, β-catenin/ZEB1↓, NF-kB↓, EMT↓, Casp↑,
2639- Api,    Plant flavone apigenin: An emerging anticancer agent
- Review, Var, NA
*antiOx↑, *Inflam↓, AntiCan↑, ChemoSen↑, BioEnh↑, chemoPv↑, IL6↓, STAT3↓, NF-kB↓, IL8↓, eff↝, Akt↓, PI3K↓, HER2/EBBR2↓, cycD1/CCND1↓, CycD3↓, p27/CDKN1B↑, FOXO3↑, STAT3↓, MMP2↓, MMP9↓, VEGF↓, Twist↓, MMP↓, ROS↑, NADPH↑, NRF2↓, SOD↓, COX2/PTGS2↓, p38↑, Telomerase↓, HDAC↓, HDAC1↓, HDAC3↓, Hif1a↓, angioG↓, uPA↓, Ca+2↑, Bax:Bcl2↑, Cyt‑c↑, Casp9↑, Casp12↑, Casp3↑, cl‑PARP↑, E-cadherin↑, β-catenin/ZEB1↓, cMyc↓, CDK4↓, CDK2↓, CDK6↓, IGF-1↓, CK2↓, CSCs↓, FAK↓, Gli↓, GLUT1↓,
1546- Api,    Apigenin in Cancer Prevention and Therapy: A Systematic Review and Meta-Analysis of Animal Models
- Review, NA, NA
TumVol↓, TumW↓, AntiCan↑, Apoptosis↑, TumCCA↑,
3382- ART/DHA,    Repurposing Artemisinin and its Derivatives as Anticancer Drugs: A Chance or Challenge?
- Review, Var, NA
AntiCan↑, toxicity↑, Ferroptosis↑, ROS↑, TumCCA↑, BioAv↝, eff↝, Half-Life↓, Ferritin↓, GPx4↓, NADPH↓, GSH↓, BAX↑, Cyt‑c↑, cl‑Casp3↑, VEGF↓, IL8↓, COX2/PTGS2↓, MMP9↓, E-cadherin↑, MMP2↓, NF-kB↓, p16↑, CDK4↓, cycD1/CCND1↓, p62↓, LC3II↑, EMT↓, CSCs↓, Wnt↓, β-catenin/ZEB1↓, uPA↓, TumAuto↑, angioG↓, ChemoSen↑,
5382- ART/DHA,    A phase I study of intravenous artesunate in patients with advanced solid tumor malignancies
- Trial, Var, NA
AntiCan↑, Dose↝, Dose↝,
5378- ART/DHA,    Natural Agents Modulating Ferroptosis in Cancer: Molecular Pathways and Therapeutic Perspectives
- Review, Var, NA
Ferroptosis↑, Iron↑, lipid-P↑, MOMP↑, AntiCan↑, NCOA4↑, GSH↓, GPx4↓, ROS↑, ChemoSen↑, ER Stress↑, DNAdam↑, angioG↓, TumCCA↑, eff↓,
5377- ART/DHA,    Dihydroartemisinin-induced ferroptosis in acute myeloid leukemia: links to iron metabolism and metallothionein
- in-vitro, AML, NA
AntiCan↑, Ferroptosis↑, Iron↑, Mets↑, eff↑, GSH↝, eff↑, other↓, eff↑, other↓,
5395- Ash,    Withaferin A Targets Heat Shock Protein 90 in Pancreatic Cancer Cells
- vitro+vivo, PC, PANC1 - in-vitro, PC, MIA PaCa-2
TumCP↓, HSP90↓, Akt↓, CDK4↓, TumCG↓, Apoptosis↑, AntiCan↑,
5384- AsP,  MEL,    Synergistic Anticancer Effect of Melatonin and Ascorbyl Palmitate Nanoformulation: A Promising Combination for Cancer Therapy
- in-vivo, Var, NA
AntiCan↑, TumCG↓, Apoptosis↑, DNAdam↑, TumCCA↑, IL6↓, STAT3↓, TumCP↓, Ki-67↓, TumCI↓, TumMeta↓, MMP9↓, eff↑, *Catalase↑, *SOD↑, *GSH↑, *MDA↓, *NO↓, *antiOx↑, *hepatoP↑, *RenoP↑,
4814- ASTX,    Chemopreventive and therapeutic efficacy of astaxanthin against cancer: A comprehensive review
- Review, Var, NA
Apoptosis↑, EMT↓, AntiCan↑, *cardioP↑, *neuroP↑, TumCG↓, *antiOx↑, *Bacteria↓, *Imm↑, *hepatoP↑, *AntiDiabetic↑, ROS↓, *chemoPv↑,
4804- ASTX,    Astaxanthin in cancer therapy and prevention (Review)
- Review, Var, NA - Review, AD, NA
*antiOx↑, *Inflam↓, ChemoSen⇅, chemoP↑, BioAv↑, TumCP↑, ROS⇅, Apoptosis↑, PI3K↑, Akt↑, GSK‐3β↑, NRF2↑, AntiCan↑, *neuroP↑, eff↑, AntiTum↑,
4807- ASTX,    An overview of the anticancer activity of astaxanthin and the associated cellular and molecular mechanisms
- Review, Var, NA
*antiOx↑, *neuroP↑, AntiCan↑, TumCG↓, TumCD↑, TumCMig↓, ChemoSen↑, chemoP↑, *BioAv↓, TumCP↓, TumCCA↑, Apoptosis↑, BioAv↑,
5427- ASTX,    Astaxanthin and Cancer Chemoprevention
- Review, Var, NA
chemoP↑, AntiCan↑, chemoPv↑, Risk↓, lipid-P↓, Pain↓, BioAv↑, Dose↝,
5419- ASTX,    Astaxanthin and other Nutrients from Haematococcus pluvialis—Multifunctional Applications
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiDiabetic↓, AntiCan↑, *lipid-P↓, TumCP↓, Apoptosis↑, TumCCA↑, *SOD↑, *PGE2↓, *NO↓, *IL8↓, *IFN-γ↓, *cardioP↑, *NF-kB↓, *TNF-α↓, *BioAv↑,
5424- ASTX,    Astaxanthin exerts an adjunctive anti-cancer effect through the modulation of gut microbiota and mucosal immunity
- in-vivo, Nor, NA
*GutMicro↑, AntiCan↑, eff↑, AntiTum↑, ChemoSen↑,
5362- AV,    Anti-cancer effects of aloe-emodin: a systematic review
- Review, Var, NA
AntiCan↑, eff↝, TumCP↓, TumCMig↓, TumCI↓, TumCCA↑, TumCD↑, MMP↓, ROS↑, Apoptosis↑, CDK1↓, CycB/CCNB1↓, Bcl-2↓, PCNA↓, ATP↓, ER Stress↑, cl‑Casp3↑, cl‑Casp9↑, cl‑PARP↑, MMP2↓, Ca+2↑, DNAdam↑, Akt↓, PKCδ↓, mTORC2↓, GSH↓, ChemoSen↑,

Showing Research Papers: 1 to 50 of 345
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 345

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

6IL↑, 1,   AApath↓, 1,   ABCG1↓, 1,   AntiBio↑, 1,   APG↓, 1,   ATGL/PNPLA2↓, 1,   CLDN7↑, 1,   DHODH↓, 1,   DIDO1/DIO-1↑, 1,   FFA/NEFA↓, 1,   FGFR4/CD334↓, 1,   HSL/LIPE↓, 1,   p‑HSL/LIPE↑, 1,   HSP60/HSPD1↓, 1,   HTRA↓, 1,   KCNH2/hERG↓, 1,   miR-199↓, 1,   PDE3B↓, 1,   PSEN2/PS-2↓, 1,   Rictor↓, 1,   SRC3↓, 1,   TF-Ag↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 4,   antiOx↑, 19,   antiOx⇅, 1,   ARE↑, 1,   Catalase↓, 2,   Catalase↑, 3,   CYP1A1↓, 2,   CYP1A1↑, 1,   CYP2E1↑, 1,   Ferroptosis↑, 10,   GPx↓, 1,   GPx↑, 2,   GPx4↓, 9,   GPx4↑, 1,   GSH↓, 23,   GSH↑, 3,   GSH↝, 1,   GSH∅, 1,   GSH/GSSG↓, 1,   GSTs↑, 4,   H2O2↓, 1,   H2O2↑, 3,   HO-1↓, 3,   HO-1↑, 1,   HO-2↑, 1,   Iron↓, 1,   Iron↑, 5,   i-Iron↑, 3,   c-Iron↑, 1,   lipid-P?, 1,   lipid-P↓, 3,   lipid-P↑, 9,   MAD↓, 1,   MDA↓, 2,   MDA↑, 3,   Mets↑, 1,   NQO1↑, 1,   NRF2↓, 5,   NRF2↑, 7,   NRF2↝, 1,   OXPHOS↝, 1,   mt-OXPHOS↑, 1,   Prx↓, 2,   PYCR1↓, 1,   ROS?, 1,   ROS↓, 14,   ROS↑, 136,   ROS⇅, 3,   ROS↝, 2,   mt-ROS↑, 1,   selenoP↓, 1,   SIRT3↑, 1,   SOD↓, 5,   SOD↑, 4,   TBARS↑, 1,   Thiols↓, 3,   Trx↓, 2,   TrxR↓, 3,   TrxR1↓, 3,   TrxR2↓, 1,   xCT/SLC7A11↓, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   IronCh↑, 1,   NCOA4↑, 1,   Tf↓, 1,   Tf↑, 2,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 3,   ATP↓, 9,   i-ATP↓, 1,   CDC25↓, 3,   EGF↓, 1,   ETC?, 1,   ETC↓, 2,   FGFR1↓, 1,   Insulin↓, 2,   MEK↓, 1,   MMP↓, 53,   MMP↑, 3,   MPT↑, 2,   mtDam↑, 9,   OCR↓, 6,   PHB↓, 1,   Raf↓, 1,   XIAP↓, 11,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

Ac-histone H3↑, 1,   Acetyl-CoA↓, 1,   ACLY↓, 1,   ACSL4↑, 1,   AKT1↓, 1,   ALAT↓, 1,   AMPK↑, 7,   CAIX/CA9↓, 1,   CAIX/CA9↑, 1,   cMyc↓, 12,   CREB↓, 1,   CRM↑, 1,   CYP3A2↓, 1,   CYP3A4↓, 2,   ECAR↓, 1,   FASN↓, 2,   glucose↓, 2,   GlucoseCon↓, 1,   GlucoseCon∅, 1,   Glycolysis↓, 11,   H2S↑, 1,   Histones↑, 1,   HK2↓, 4,   lactateProd↓, 2,   lactateProd∅, 1,   LAT↓, 1,   LDH↓, 6,   LDH↑, 1,   LDH↝, 1,   LDHA↓, 3,   LDL↓, 1,   NAD↓, 1,   NADPH↓, 3,   NADPH↑, 2,   PDH↑, 2,   PDH↝, 1,   PDK1 / PDPK1↓, 2,   PDKs↓, 1,   PFK↓, 1,   PI3K/Akt↑, 1,   PIK3CA↓, 1,   PKM2↓, 6,   polyA↓, 1,   PPARα↓, 1,   PPARγ↑, 2,   PSMB5↓, 1,   S6K↓, 1,   SIRT1↓, 4,   SIRT1↑, 5,   SREBP1/SREBF1↓, 1,   SREBP2↓, 1,   STK11/LKB1↑, 1,   TS↓, 1,   Warburg↓, 6,  

Cell Death(tgid=5) ⓘ

Akt↓, 57,   Akt↑, 2,   p‑Akt↓, 10,   APAF1↑, 2,   Apoptosis?, 2,   Apoptosis↓, 1,   Apoptosis↑, 142,   mt-Apoptosis↑, 2,   ATF2↓, 2,   BAD↓, 2,   BAD↑, 3,   Bak↓, 1,   Bak↑, 5,   BAX↓, 1,   BAX↑, 49,   Bax:Bcl2↑, 13,   Bcl-2↓, 55,   Bcl-xL↓, 4,   BID↓, 1,   BID↑, 2,   BIM↑, 1,   Casp↓, 1,   Casp↑, 18,   Casp12↑, 2,   Casp3↓, 2,   Casp3↑, 49,   cl‑Casp3↑, 12,   proCasp3↑, 1,   pro‑Casp3↑, 1,   Casp7↑, 7,   cl‑Casp7↑, 1,   Casp8↑, 16,   Casp8∅, 1,   cl‑Casp8↑, 1,   Casp9↑, 33,   p‑Casp9↑, 1,   cl‑Casp9↑, 5,   CBP↓, 1,   cFLIP↓, 1,   Chk2↑, 2,   CK2↓, 2,   Cyt‑c↑, 38,   Diablo↑, 1,   DR4↑, 4,   DR5↑, 6,   FADD↑, 2,   Fas↓, 2,   Fas↑, 9,   FasL↑, 4,   Ferroptosis↑, 10,   GADD34↑, 1,   GRP58↓, 1,   cl‑GSDME↑, 1,   GSDME-N↑, 1,   hTERT/TERT↓, 3,   IAP1↓, 2,   iNOS↓, 3,   iNOS↑, 1,   JNK↑, 6,   p‑JNK↑, 3,   MAPK↓, 19,   MAPK↑, 10,   Mcl-1↓, 3,   MCT1↓, 1,   MDM2↓, 2,   MKP1↝, 1,   MOMP↑, 3,   Myc↓, 3,   Necroptosis↑, 3,   necrosis↑, 3,   p27/CDKN1B↓, 3,   p27/CDKN1B↑, 17,   p38↑, 4,   p‑p38↓, 2,   p‑p38↑, 2,   PUMA↑, 3,   Pyro↑, 2,   RIP1↓, 1,   survivin↓, 16,   Telomerase↓, 6,   TRAIL↑, 3,   TRPV1↑, 1,   TumCD↑, 12,  

Kinase & Signal Transduction(tgid=6) ⓘ

AMPKα↑, 1,   FOXD3↑, 1,   HCAR2↑, 2,   HER2/EBBR2↓, 9,   p70S6↓, 1,   SOX9↓, 1,   Sp1/3/4↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

BowelM↑, 1,   ChrMod↑, 1,   cJun↓, 1,   EZH2↓, 2,   p‑H3↓, 1,   ac‑H3↑, 1,   ac‑H4↑, 1,   HATs↓, 2,   HATs↑, 1,   miR-21↓, 1,   miR-27a-3p↓, 1,   miR-30a-5p↑, 1,   other↓, 4,   other↑, 4,   other↝, 13,   other∅, 1,   PCAF↓, 1,   PhotoS↑, 1,   pRB↓, 3,   p‑pRB↓, 1,   tumCV?, 1,   tumCV↓, 35,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 6,   eIF2α↑, 1,   ER Stress↑, 17,   ERStress↑, 1,   GRP78/BiP↑, 1,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↑, 1,   HSP90↓, 6,   PERK↑, 1,   UPR↑, 4,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 2,   Beclin-1/ATG6↑, 4,   LC3B↑, 1,   LC3B-II↑, 1,   LC3II↑, 7,   LC3s↑, 1,   p62↓, 3,   p62↑, 4,   TumAuto↓, 1,   TumAuto↑, 29,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↑, 2,   BRCA1↓, 1,   BRCA1↑, 2,   BRCA1↝, 1,   CHK1↓, 1,   CHK1↑, 2,   DFF45↓, 1,   DNAdam↑, 39,   DNArepair↑, 2,   DNMT1↓, 2,   DNMT3A↓, 1,   DNMTs↓, 2,   p16↑, 2,   P53↑, 31,   p‑P53↓, 1,   p‑P53↑, 2,   PARP↑, 6,   p‑PARP↑, 1,   cl‑PARP↑, 24,   PARP1↑, 1,   cl‑PARP1↑, 1,   PCNA↓, 13,   TP53↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 4,   CDK2↓, 9,   CDK2↑, 2,   CDK4↓, 19,   Cyc↓, 1,   cycA1/CCNA1↓, 2,   CycB/CCNB1↓, 8,   CycB/CCNB1↑, 1,   cycD1/CCND1↓, 24,   CycD3↓, 1,   cycE/CCNE↓, 7,   cycE/CCNE↑, 1,   E2Fs↓, 1,   p19↑, 1,   P21↓, 3,   P21↑, 28,   RB1↑, 1,   p‑RB1↓, 2,   TumCCA?, 1,   TumCCA↓, 1,   TumCCA↑, 104,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

4E-BP1↓, 1,   ALDH↓, 1,   CD44↓, 5,   p‑cDC2↓, 1,   cFos↓, 3,   CIP2A↓, 1,   CSCs↓, 16,   CSCs↑, 1,   CSCsMark↓, 1,   CTNNB1↓, 1,   Diff↑, 4,   EIF4E↓, 1,   EMT↓, 20,   EMT↑, 1,   EpCAM↓, 2,   ERK↓, 25,   ERK↑, 2,   p‑ERK↓, 5,   FGF↓, 1,   FOXO3↓, 1,   FOXO3↑, 2,   FOXO3↝, 1,   Gli↓, 1,   Gli1↓, 3,   GSK‐3β↓, 3,   GSK‐3β↑, 2,   p‑GSK‐3β↓, 1,   p‑GSK‐3β↑, 1,   HDAC↓, 12,   HDAC1↓, 5,   HDAC2↓, 2,   HDAC3↓, 2,   HDAC4↓, 1,   HDAC8↓, 3,   HH↓, 1,   IGF-1↓, 10,   IGF-1R↓, 1,   IGFBP3↑, 1,   IGFR↓, 1,   Let-7↑, 1,   LRP6↓, 1,   miR-34a↓, 1,   miR-34a↑, 2,   mTOR↓, 31,   p‑mTOR↓, 4,   mTORC1↓, 2,   mTORC2↓, 1,   Nanog↓, 1,   NOTCH↓, 6,   NOTCH1↓, 5,   NOTCH3↓, 1,   OCT4↓, 3,   p300↓, 2,   PI3K↓, 48,   PI3K↑, 2,   p‑PI3K↑, 1,   PTEN↓, 1,   PTEN↑, 4,   RAS↓, 5,   Shh↓, 1,   Smo↓, 1,   SOX2↓, 2,   Src↓, 1,   STAT↓, 2,   STAT3↓, 25,   STAT3↑, 1,   p‑STAT3↓, 1,   STAT5↓, 1,   STAT6↓, 1,   TOP1↓, 6,   TOP2↓, 2,   TOP2↑, 1,   TRPM7↓, 1,   TumCG↓, 58,   TumCG↑, 2,   Wnt↓, 18,   Wnt↑, 1,   Wnt/(β-catenin)↓, 1,  

Migration(tgid=13) ⓘ

5LO↓, 1,   AntiAg?, 1,   AP-1↓, 1,   ATPase↓, 1,   CA↓, 1,   Ca+2↓, 1,   Ca+2↑, 14,   Ca+2↝, 1,   CC(CDKs/cyclins)↓, 1,   CCN2/CTGF↓, 1,   CD31/PECAM-1↓, 1,   Cdc42↓, 1,   CDK4/6↓, 1,   CEA↓, 1,   CLDN1↑, 1,   E-cadherin↑, 17,   FAK↓, 9,   p‑FAK↓, 1,   hnRNPA1↓, 1,   ITGB1↓, 1,   ITGB6↓, 1,   Ki-67↓, 9,   MALAT1↓, 1,   MARK4↓, 1,   miR-155↓, 1,   miR-200b↑, 2,   miR-200c↑, 1,   miR-203↑, 1,   MMP1↓, 5,   MMP13↓, 3,   MMP2↓, 30,   MMP3↓, 3,   MMP7↓, 2,   MMP9↓, 32,   MMP9↑, 1,   MMPs↓, 7,   N-cadherin↓, 8,   NFAT↑, 1,   PAK1↓, 1,   PDGF↓, 3,   p‑PKA↓, 1,   PKCδ↓, 5,   PKCδ↑, 1,   RECK↑, 1,   Rho↓, 2,   RIP3↓, 1,   ROCK1↓, 1,   Slug↓, 2,   Smad1↓, 1,   SMAD4↓, 1,   Snail↓, 5,   TET1↑, 1,   TGF-β↓, 7,   TGF-β↑, 1,   TGF-β1↓, 2,   TIMP1↓, 2,   TIMP1↑, 4,   TIMP2↓, 1,   TIMP2↑, 6,   TIMP3↑, 1,   TJ↑, 1,   Treg lymp↓, 2,   TRIB3↑, 1,   TumCA↓, 3,   TumCI↓, 32,   TumCMig↓, 36,   TumCMig↑, 2,   TumCP↓, 80,   TumCP↑, 3,   TumMeta↓, 41,   TumMeta↑, 2,   Twist↓, 5,   TXNIP↑, 1,   uPA↓, 4,   VEGFR1↓, 1,   Vim↓, 10,   Zeb1↓, 4,   ZEB2↓, 2,   ZO-1↑, 1,   α-tubulin↓, 2,   β-catenin/ZEB1↓, 22,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 58,   angioG↑, 1,   ATF4↑, 1,   EGFR↓, 11,   EGFR↑, 1,   Endoglin↑, 1,   eNOS↑, 1,   EPR↑, 5,   HIF-1↓, 3,   Hif1a↓, 24,   LOX1↓, 1,   LymphAG↓, 1,   NO↓, 1,   p‑PDGFR-BB↓, 1,   PHDs↓, 1,   VEGF↓, 38,   VEGF↑, 1,   VEGFR2/KDR/Flk1↓, 5,  

Barriers & Transport(tgid=15) ⓘ

AQPs↓, 1,   BBB↑, 3,   CellMemb↓, 1,   CellMemb↑, 2,   GLUT1↓, 5,   GLUT1↑, 1,   GLUT3↑, 1,   IBI↑, 1,   NHE1↓, 1,   OCLN↑, 1,   P-gp/ABCB1↓, 9,   P-gp/ABCB1⇅, 1,   SLC12A5↓, 1,   SVCT-2↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

ANXA1↓, 1,   CD14↓, 1,   CD4+↓, 1,   CD4+↑, 3,   cellSen↑, 1,   COX2/PTGS2↓, 27,   COX2/PTGS2↑, 1,   COX2/PTGS2↝, 1,   CRP↓, 2,   CXCR4↓, 3,   DCells↑, 1,   Dectin1↝, 1,   FOXP3↓, 1,   HCAR2↑, 2,   HMGB1↓, 1,   IFN-γ↑, 3,   Igs↓, 1,   IKKα↓, 1,   IL1↓, 3,   IL10↓, 2,   IL10↑, 2,   IL12↑, 2,   IL18↑, 1,   IL1α↓, 1,   IL1β↓, 4,   IL1β↑, 1,   IL2↑, 1,   IL4↓, 1,   IL4↑, 1,   IL6↓, 15,   IL8↓, 6,   Imm↑, 8,   Imm↝, 1,   INF-γ↓, 1,   Inflam↓, 29,   Inflam↝, 1,   JAK↓, 1,   JAK1↓, 1,   JAK2↓, 6,   M2 MC↓, 1,   MCP1/CCL2↓, 2,   MIP2↓, 1,   mPGES-1↓, 1,   NF-kB↓, 60,   NF-kB↑, 5,   NK cell↑, 8,   p65↓, 1,   PD-1↓, 1,   PD-L1↓, 4,   PGE2↓, 4,   PSA↓, 5,   PSA∅, 1,   T-Cell↑, 1,   Th1 response↑, 1,   TLR4↓, 3,   TNF-α↓, 10,   TNF-α↑, 2,  

Cellular Microenvironment(tgid=17) ⓘ

NOX↓, 1,   pH↝, 1,   e-pH↑, 1,   i-pH↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,  

Protein Aggregation(tgid=19) ⓘ

NLRP3↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 4,   CDK6↓, 5,   CYP19↓, 1,   ERα/ESR1↓, 1,   ERβ/ESR2↑, 1,   EstroRS/ERS↓, 1,   GR↑, 1,   RANKL↓, 1,   SXR↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 32,   BioAv↑, 33,   BioAv⇅, 1,   BioAv↝, 9,   BioEnh↑, 2,   ChemoSen↓, 3,   ChemoSen↑, 89,   ChemoSen⇅, 1,   ChemoSen↝, 1,   ChemoSen∅, 1,   CYP1A2↓, 1,   CYP1A2↑, 1,   CYP2A3/CYP2A6↓, 1,   Dose?, 3,   Dose↓, 1,   Dose↑, 5,   Dose↝, 35,   Dose∅, 11,   eff↓, 23,   eff↑, 105,   eff↝, 8,   eff∅, 2,   Half-Life↓, 5,   Half-Life↑, 1,   Half-Life↝, 2,   Half-Life∅, 1,   MDR1↓, 1,   P450↓, 2,   RadioS↓, 1,   RadioS↑, 23,   selectivity↓, 1,   selectivity↑, 55,   selectivity↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 1,   ALAT↓, 1,   AR↓, 4,   ascitic↓, 1,   BG↓, 1,   BRCA1↓, 1,   BRCA1↑, 2,   BRCA1↝, 1,   CEA↓, 1,   CRP↓, 2,   EGFR↓, 11,   EGFR↑, 1,   ERα/ESR1↓, 1,   EstroRS/ERS↓, 1,   EZH2↓, 2,   Ferritin↓, 1,   GutMicro↑, 4,   GutMicro↝, 2,   HER2/EBBR2↓, 9,   hTERT/TERT↓, 3,   IL6↓, 15,   Ki-67↓, 9,   LDH↓, 6,   LDH↑, 1,   LDH↝, 1,   Maspin↑, 1,   Myc↓, 3,   PD-L1↓, 4,   PSA↓, 5,   PSA∅, 1,   TG/TAG↓, 1,   TP53↓, 1,   TRIB3↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 347,   AntiDiabetic↑, 1,   antiNeop↑, 3,   AntiTum↓, 1,   AntiTum↑, 13,   Appetite↑, 1,   breath↑, 1,   cardioP↑, 9,   CardioT↓, 1,   chemoP↑, 19,   chemoPv↑, 18,   ChemoSideEff↓, 5,   hepatoP↑, 8,   neuroP↑, 5,   OS↑, 8,   OS⇅, 1,   Pain↓, 4,   Pin1↓, 1,   QoL↑, 4,   radioP↑, 5,   Remission↑, 2,   RenoP↑, 3,   Risk↓, 25,   Sleep↑, 1,   Strength↑, 2,   toxicity↓, 12,   toxicity↑, 2,   toxicity⇅, 1,   toxicity↝, 8,   toxicity∅, 2,   TumVol↓, 14,   TumW↓, 5,   Weight↑, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 1,   Bacteria↓, 2,   CD8+↑, 4,   Dectin1↝, 1,   Sepsis↓, 1,  
Total Targets: 705

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 13,   colonLen↑, 1,   diuretic↑, 2,   FFA/NEFA↓, 1,   IRes↓, 1,   Stroke↓, 3,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 6,   antiOx↑, 76,   Catalase↑, 23,   GCLC↑, 1,   GCLM↑, 1,   GPx↑, 17,   GPx1↑, 1,   GSH↓, 1,   GSH↑, 17,   GSR↑, 4,   GSTA1↑, 1,   GSTs↑, 6,   H2O2↓, 2,   HDL↓, 1,   HDL↑, 1,   HO-1↓, 1,   HO-1↑, 5,   Iron↓, 1,   Keap1↓, 2,   Keap1↑, 1,   lipid-P↓, 20,   MDA↓, 12,   MDA↑, 1,   MPO↓, 2,   NRF2↓, 1,   NRF2↑, 16,   Prx↑, 1,   ROS?, 1,   ROS↓, 57,   ROS↑, 1,   SAM-e↑, 1,   selenoP↑, 4,   SIRT3↑, 1,   SOD↑, 29,   SOD1↑, 2,   SOD2↑, 1,   TAC↑, 2,   TBARS↓, 2,   uricA↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 3,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 1,   ATP↑, 3,   ATP↝, 1,   Insulin↓, 2,   Insulin↑, 1,   mitResp↑, 1,   MMP↑, 4,   mtDam↓, 1,   PGC-1α↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT?, 1,   ALAT↓, 6,   AMPK↓, 1,   AMPK↑, 3,   BUN↓, 1,   cMyc↓, 1,   CRM↑, 2,   FASN↓, 1,   glucose↓, 1,   glucose↝, 1,   GlucoseCon↑, 1,   glyC↓, 1,   H2S↑, 1,   LDH↓, 5,   LDL↓, 6,   NAD↓, 1,   NAD↝, 1,   PPARγ↑, 1,   SIRT1↑, 2,  

Cell Death(tgid=5) ⓘ

Akt↓, 2,   Akt↑, 1,   Apoptosis↓, 3,   BAX↓, 6,   Bcl-2↓, 1,   Bcl-2↑, 4,   Casp3↓, 7,   Casp9↓, 4,   Cyt‑c↓, 2,   GADD34↓, 1,   GSDMD↓, 1,   iNOS↓, 9,   iNOS↑, 1,   JNK↑, 2,   MAPK↓, 3,   MAPK↑, 2,   TUNEL↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 2,   HATs↓, 2,   other↓, 2,   other↑, 4,   other↝, 7,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 1,   cl‑eIF2α↑, 1,   GRP78/BiP↑, 1,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↑, 2,   p‑PERK↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,   LC3II↓, 1,   p62↓, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 3,   DNArepair↑, 1,   P53↓, 2,   PCNA↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,   P21↓, 2,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

EMT↓, 1,   EP300↓, 1,   ERK↓, 1,   GSK‐3β↓, 2,   HDAC↓, 1,   HDAC2↓, 1,   mTOR↓, 2,   p‑mTOR↓, 1,   mTORC1↓, 1,   PI3K↓, 3,   PI3K↑, 1,   STAT3↓, 1,   STAT3↑, 2,  

Migration(tgid=13) ⓘ

5LO↓, 1,   AntiAg↑, 4,   AP-1↓, 1,   APP↓, 1,   Ca+2↓, 1,   Ca+2↝, 2,   Ca+2∅, 1,   COL1↓, 1,   E-cadherin↑, 1,   MMP13↓, 1,   MMP9↓, 4,   PKCδ↑, 1,   serineP↓, 1,   TGF-β↓, 1,   TIMP1↓, 1,   TumCI↓, 1,   TumCP↓, 1,   Vim↓, 1,   α-SMA↓, 1,   β-Endo↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

ATF4↓, 1,   eNOS↑, 1,   Hif1a↓, 1,   NO↓, 4,   NO↑, 2,   VEGF↓, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 4,   GastroP↑, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CB2 / CNR2↑, 1,   CD4+↑, 2,   COX2/PTGS2↓, 13,   CRP↓, 2,   IFN-γ↓, 4,   IL1↓, 1,   IL10↓, 1,   IL10↑, 1,   IL12↓, 3,   IL17↓, 3,   IL1β↓, 11,   IL23↓, 1,   IL6↓, 11,   IL6↑, 1,   IL8↓, 2,   Imm↓, 1,   Imm↑, 8,   Imm⇅, 2,   Inflam↓, 88,   Inflam↑, 2,   IP-10/CXCL-10↓, 1,   LPS↓, 1,   MCP1/CCL2↓, 2,   MyD88↓, 1,   NF-kB?, 1,   NF-kB↓, 15,   NF-kB↑, 2,   NK cell↑, 1,   PGE2↓, 6,   PGE2↑, 1,   TLR2↓, 2,   TLR4↓, 3,   TNF-α↓, 20,   TNF-α↑, 1,   TRIF↓, 1,   VitD↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 1,   5HT↑, 1,   AChE↓, 9,   BChE↓, 3,   BDNF↓, 1,   BDNF↑, 1,   tau↓, 2,   p‑tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 2,   Aβ↓, 9,   BACE/β-secretase↓, 3,   XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

BNP↓, 1,   testos↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv?, 1,   BioAv↓, 16,   BioAv↑, 26,   BioAv⇅, 1,   BioAv↝, 6,   Dose↑, 1,   Dose↝, 8,   eff↑, 16,   eff↝, 1,   Half-Life↓, 4,   Half-Life↝, 5,   Half-Life∅, 1,   P450↓, 1,   selectivity↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT?, 1,   ALAT↓, 6,   ALP↓, 1,   AST↓, 7,   BloodF↑, 1,   BMD↑, 4,   BMPs↑, 1,   BP↓, 7,   Calcium↑, 1,   creat↓, 3,   CRP↓, 2,   GutMicro↑, 10,   hs-CRP↓, 1,   IL6↓, 11,   IL6↑, 1,   LDH↓, 5,   Mag↑, 1,   VitD↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 9,   AntiArt↑, 5,   AntiCan↑, 1,   AntiDiabetic↓, 1,   AntiDiabetic↑, 24,   AntiP↑, 1,   AntiTum↑, 2,   cardioP↓, 1,   cardioP↑, 27,   CardioT↓, 1,   chemoP↑, 6,   chemoPv↑, 4,   ChemoSideEff↓, 1,   cognitive↓, 1,   cognitive↑, 12,   hepatoP↑, 24,   memory↑, 8,   Mood↑, 1,   motorD↑, 2,   neuroP↑, 48,   NP/CIPN↓, 1,   Obesity↓, 1,   OS↑, 3,   Pain↓, 2,   radioP↑, 3,   RenoP↑, 4,   Risk↓, 1,   toxicity↓, 24,   toxicity↑, 2,   toxicity↝, 10,   toxicity∅, 4,   Weight↓, 2,   Weight∅, 1,   Wound Healing↑, 4,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 6,   AntiViral↑, 10,   Bacteria↓, 27,   CD8+↑, 1,   Diar↓, 1,   IRF3↓, 1,  
Total Targets: 275

Scientific Paper Hit Count for: AntiCan, Anticancer Effect
18 Silver-NanoParticles
9 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
9 Selenium NanoParticles
8 Thymoquinone
8 Magnolol
8 Inositol
7 Emodin
7 Gambogic Acid
7 Lycopene
6 Vitamin C (Ascorbic Acid)
6 Allicin (mainly Garlic)
6 Astaxanthin
6 Phenethyl isothiocyanate
6 Quercetin
6 Sulforaphane (mainly Broccoli)
5 Artemisinin
5 Curcumin
5 Honokiol
5 Isoliquiritigenin
4 Coenzyme Q10
4 chitosan
4 Boron
4 Selenium
4 Selenite (Sodium)
3 Cisplatin
3 Melatonin
3 beta-glucans
3 Baicalein
3 Biochanin A
3 Capsaicin
3 Carvacrol
3 Chlorogenic acid
3 Hydroxycinnamic-acid
3 Spermidine
3 Crocetin
3 Carvone
3 Cynara scolymus/Globe Artichoke/Artichoke Extract
3 flavonoids
3 Formononetin
3 Fucoidan
3 Gallic acid
3 Garcinol
3 HydroxyTyrosol
3 Kaempferol
3 Lactoferrin/Talactoferrin
3 Naringin
3 salinomycin
3 Silymarin (Milk Thistle) silibinin
3 Vitamin D3
3 Vitamin K2
2 3-bromopyruvate
2 5-fluorouracil
2 doxorubicin
2 Anethole/trans-Anethole
2 Apigenin (mainly Parsley)
2 Aloe anthraquinones
2 Baicalin
2 Beta-Caryophyllene
2 Boswellia (frankincense)
2 α-Bisabolol / Chamomile oil
2 Butyrate
2 Thymol-Thymus vulgaris
2 Chrysin
2 Cinnamon
2 Camptothecin
2 Cucurbitacin
2 Dichloroacetate
2 Dandelion Root
2 Ginkgo biloba-EGb 761
2 EGCG (Epigallocatechin Gallate)
2 Eugenol
2 Ferulic acid
2 Germanium Organic/Ge-132 / propagermanium (organogermanium)
2 Geraniol
2 Ginkgetin
2 Hydrogen Gas
2 Hibiscus sabdariffa
2 Hyperoside
2 Isobavachalcone
2 Licochalcone A
2 Luteolin
2 Magnetic Fields
2 Propolis -bee glue
2 Pterostilbene
2 Rosmarinic acid
2 Rauwolfia serpentina/Indian Snakeroot
2 Shikonin
2 Ursolic acid
2 VitK3,menadione
1 1,8-Cineole
1 Auranofin
1 Astragalus
1 Citric Acid
1 Alpha-Lipoic-Acid
1 Ashwagandha(Withaferin A)
1 Ascorbyl Palmitate
1 Berberine
1 Betulinic acid
1 Bromelain
1 borneol
1 Bruteridin(bergamot juice)
1 Vitamin B3,Niacin
1 Caffeic acid
1 Caffeine
1 urea
1 Celastrol
1 Centella asiatica / Gotu kola → asiaticoside
1 chaetocin
1 Chlorophyllin
1 irinotecan
1 Calorie Restriction Mimetics
1 Resveratrol
1 Aspirin
1 Polyphenols
1 Diclofenac
1 Date Fruit Extract
1 diet Fermented Foods
1 diet FMD Fasting Mimicking Diet
1 diet Methionine-Restricted Diet
1 diet Plant based
1 Lemongrass Extract/Citral
1 Ellagic acid
1 Electrical Pulses
1 Eurycomanone
1 Evodiamine
1 ferumoxytol
1 Fisetin
1 Paclitaxel/Taxol
1 Ginkgo biloba
1 Geldanamycin
1 Genistein (soy isoflavone)
1 γ-linolenic acid (Borage Oil)
1 alpha Linolenic acid
1 Graviola
1 Grapeseed extract
1 Chemotherapy
1 High-Ozonide Oil
1 Hops (Humulus lupulus)
1 Indole-3-carbinol
1 iodine
1 itraconazole
1 Ivermectin
1 Juglone
1 Licorice
1 Lecithin
1 Methylene blue
1 Photodynamic Therapy
1 mebendazole
1 Metformin
1 Magnetic Field Rotating
1 Bicarbonate(Sodium)
1 Nimbolide
1 Oleocanthal
1 Marjoram (Origanum majorana)
1 Oregano
1 Piperine
1 Piperlongumine
1 Psoralidin
1 Parthenolide
1 Gold NanoParticles
1 Salvia officinalis
1 Radiotherapy/Radiation
1 α-Santalol/Sandalwood oil
1 Calcium
1 Aflavin-3,3′-digallate
1 Urolithin
1 Magnesium
1 Zerumbone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:813  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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