TRPM7 Cancer Research Results

TRPM7, transient receptor potential melastatin 7: Click to Expand ⟱
Source:
Type:
TRPM7 (transient receptor potential melastatin 7) is a member of the TRP family of ion channels, which play a crucial role in various cellular processes, including cell growth, differentiation, and survival.
High TRPM7 expression is associated with reduced overall survival in various types of cancer, including breast, lung, colon, prostate, ovarian, pancreatic, and glioblastoma.
Scientific Papers found: Click to Expand⟱
8460- Mg,    Stimulating TRPM7 suppresses cancer cell proliferation and metastasis by inhibiting autophagy
- vitro+vivo, NA, NA
TRPM7↑, TumAuto↓, TumCD↑, TumMeta↓, TumCG?, Apoptosis↑, TumCCA↑, ROS↑, other?,
8461- Mg,    Effects of Salivary Mg on Head and Neck Carcinoma via TRPM7
- vitro+vivo, SCC, CAL27 - in-vitro, Laryn, FaDu
TumCP↑, TumCMig↑, TumCI↑, TumCG↑, TRPM7↑, Akt↑, mTOR↑, Risk↑, other↝,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

ROS↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↑, 1,   Apoptosis↑, 1,   TumCD↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other?, 1,   other↝, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

TumAuto↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

mTOR↑, 1,   TRPM7↑, 2,   TumCG?, 1,   TumCG↑, 1,  

Migration(tgid=13) ⓘ

TumCI↑, 1,   TumCMig↑, 1,   TumCP↑, 1,   TumMeta↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Risk↑, 1,  
Total Targets: 17

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: TRPM7, transient receptor potential melastatin 7
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:883  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

Home Page