E-sel Cancer Research Results

E-sel, E-selectin: Click to Expand ⟱

Source:

Type:

E-selectin is a cell adhesion molecule that plays a crucial role in the recruitment of leukocytes to sites of inflammation. In cancer, E-selectin is involved in the interaction between tumor cells and the endothelium, promoting metastasis and tumor progression.

E-selectin is expressed on the surface of endothelial cells in tumors, and its expression is associated with increased metastasis and poor prognosis.

Scientific Papers found: Click to Expand⟱

9117-

Cim,

Cimetidine inhibits cancer cell adhesion to endothelial cells and prevents metastasis by blocking E-selectin expression

vitro+vivo,

CRC,

OS↑, TumCA↓, TumMeta↓, E-sel↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:

Migration(tgid=13) ⓘ

TumCA↓, 1, TumMeta↓, 1,

Angiogenesis & Vasculature(tgid=14) ⓘ

E-sel↑, 1,

Functional Outcomes(tgid=23) ⓘ

OS↑, 1,
Total Targets: 4

Pathway results for Effect on Normal Cells:

Total Targets: 0

Scientific Paper Hit Count for: E-sel, E-selectin

Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells