eff Cancer Research Results

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Scientific Papers found: Click to Expand⟱
4384- ,    Silver nanoparticles: synthesis, properties, and therapeutic applications
- Review, Var, NA
AntiCan↑, RadioS↑, CellMemb↑, ROS↑, DNAdam↑, PhotoS↑, eff↑,
6461- 1,8-Cin,    1,8-cineole (eucalyptol): A versatile phytochemical with therapeutic applications across multiple diseases
- Review, AD, NA - Review, Var, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↑, *Half-Life↝, *toxicity↓, *PGE2↓, *TNF-α↓, *IL1β↓, *NO↓, *NF-kB↓, *PPARγ↓, COX2/PTGS2↓, *ROS↓, *SOD↑, *Catalase↑, *TAC↑, *MDA↓, *lipid-P↓, *NRF2↑, *HO-1↑, *NADPH↑, *GPx↑, *AntiBio↑, *eff↑, *AntiFungal↑, *AntiViral↑, *TRPA1↑, eff↑, TumCCA↑, ROS↑, MAPK↝, mTOR↝, Apoptosis↑, survivin↓, Akt↓, p38↑, cl‑PARP↑, cl‑Casp3⇅, P53↑, BAX↑, Cyt‑c↑, Casp9↑, Dose↝, *Aβ↓, *tau↓, *GSK‐3β↓, *BACE/β-secretase↓, *cardioP↑, MFN2↑,
6474- 1,8-Cin,    Molecular Docking Identifies 1,8-Cineole (Eucalyptol) as A Novel PPARγ Agonist That Alleviates Colon Inflammation
- in-vitro, Nor, HT29 - in-vivo, Nor, NA - in-vivo, IBD, NA
*Inflam↓, *NRF2↑, *antiOx↑, *PPARγ↑, eff↑,
6462- 1,8-Cin,    Modes of Action of 1,8-Cineol in Infections and Inflammation
- Review, Var, NA - Review, AD, NA
*BioAv↑, *BBB↑, *AntiViral↑, *Bacteria↓, *AntiFungal↑, *Inflam↓, *BioAv↑, *MUC2↓, *MUC19↓, *NF-kB↓, *ICAM-1↓, *VCAM-1↓, DNAdam↑, *lipid-P↓, *PGE2↓, *IL4↓, *IL6↓, *IL1β↓, *IL6↓, eff↑, TGF-β↓, fascin↓, VEGF↓, MMP9↓, *MAPK↓, *ERK↓, JNK↓, Wnt↓, β-catenin/ZEB1↓, GSK‐3β↑, *neuroP↑, *GSK‐3β↓, *AGEs↓, *BBB↑, *NLRP3↓,
2325- 2DG,    Research Progress of Warburg Effect in Hepatocellular Carcinoma
- Review, Var, NA
HK2↓, Glycolysis↓, PKM2↓, LDHA↓, TumCD↑, ChemoSen↑, eff↑,
1340- 3BP,    Safety and outcome of treatment of metastatic melanoma using 3-bromopyruvate: a concise literature review and case study
- Review, NA, NA
Glycolysis↓, HK2↓, LDH↓, OXPHOS↓, angioG↓, H2O2↑, eff↑,
1341- 3BP,    The HK2 Dependent “Warburg Effect” and Mitochondrial Oxidative Phosphorylation in Cancer: Targets for Effective Therapy with 3-Bromopyruvate
- Review, NA, NA
Glycolysis↓, OXPHOS↓, *toxicity↓, ROS↑, GSH↓, eff↑,
5282- 3BP,  Rad,    3-Bromopyruvate-mediated MCT1-dependent metabolic perturbation sensitizes triple negative breast cancer cells to ionizing radiation
- in-vitro, BC, MDA-MB-231 - in-vitro, BC, MDA-MB-468
Glycolysis↓, RadioS↑, eff↑, GAPDH↓, PPP↑, GSH↓, ECAR↓,
5278- 3BP,    effect-of-3-bromopyruvate-on-human-colorectal">The effect of 3-bromopyruvate on human colorectal cancer cells is dependent on glucose concentration but not hexokinase II expression
- in-vitro, CRC, HCT116 - in-vitro, CRC, Caco-2 - in-vitro, CRC, SW48
ATP↓, TumCD↑, selectivity↑, toxicity↓, OS↑, HK2?, Cyt‑c↑, eff↑, p‑Akt↑,
5274- 3BP,    ME3BP-7 is a targeted cytotoxic agent that rapidly kills pancreatic cancer cells expressing high levels of monocarboxylate transporter MCT1
- in-vitro, PC, NA
eff↑, TumCG↓, TumMeta↓, toxicity↝, Glycolysis↓, toxicity↓, Dose↝,
5272- 3BP,    The efficacy of the anticancer 3-bromopyruvate is potentiated by antimycin and menadione by unbalancing mitochondrial ROS production and disposal in U118 glioblastoma cells
- in-vitro, GBM, U87MG - in-vitro, Nor, HEK293
Glycolysis↓, ROS↑, GPx↓, eff↓, OXPHOS↓, HK2↓, ATP↓, ROS↑, ER Stress↑, BioAv↓, Cyt‑c↑, eff↑,
5263- 3BP,  CET,    3-Bromopyruvate overcomes cetuximab resistance in human colorectal cancer cells by inducing autophagy-dependent ferroptosis
- in-vitro, CRC, DLD1 - NA, NA, HCT116
eff↑, Ferroptosis↓, TumAuto↑, Apoptosis↑, FOXO3↑, AMPKα↑, p‑Beclin-1/ATG6↑, HK2↓, ATP↓, ROS↑, Dose↝, TumVol↓, TumW↓, xCT/SLC7A11↑, GSH↓, eff↓, MDA↑,
5259- 3BP,    Advanced cancers: eradication in all cases using 3-bromopyruvate therapy to deplete ATP
- in-vivo, HCC, NA
ATP↓, TumCD↑, toxicity↓, eff↑, tumCV↓, Dose↝,
5260- 3BP,    Systemic Delivery of Microencapsulated 3-Bromopyruvate for the Therapy of Pancreatic Cancer
- in-vivo, PC, NA
TumCG↓, toxicity↓, BioAv↝, GAPDH↓, toxicity↑, Dose↝, ATP↓, eff↑, TumCI↓, MMP9↓, toxicity↓,
5261- 3BP,    The cytotoxicity of 3-bromopyruvate in breast cancer cells depends on extracellular pH
- in-vitro, BC, NA
eff↑, eff↓,
5269- 3BP,    The anti-metabolite KAT/3BP has in vitro and in vivo anti-tumor activity in lymphoma models.
- in-vitro, HCC, NA
toxicity↑, eff↝, eff↑, Glycolysis↓, HK2↓, AIF↑, Apoptosis↑, NK cell↑, toxicity↑, toxicity↓, Dose↝, AntiTum↑,
5264- 3BP,    Candidate cancer drug suspected after death of three patients at an alternative medicine clinic
- Review, Var, NA
toxicity↑, Glycolysis↓, eff↑, OS↑, QoL↑, toxicity↝,
5266- 3BP,    3-bromopyruvate-based agent KAT-101
- Review, Var, NA
eff↑, Glycolysis↓, OXPHOS↓, ATP↓, TumCP↓, Apoptosis↑, HK2↓, MPT↑, LDH↓, PDH↓,
4774- 5-FU,  TQ,  CoQ10,    Exploring potential additive effects of 5-fluorouracil, thymoquinone, and coenzyme Q10 triple therapy on colon cancer cells in relation to glycolysis and redox status modulation
- in-vitro, CRC, NA
AntiCan↑, TumCCA↑, Apoptosis↑, eff↑, Bcl-2↓, survivin↓, P21↑, p27/CDKN1B↑, BAX↑, Cyt‑c↑, Casp3↑, PI3K↓, Akt↓, mTOR↓, Hif1a↓, PTEN↑, AMPKα↑, PDH↑, LDHA↓, antiOx↓, ROS↑, AntiCan↑,
3973- ACNs,    Saskatoon and wild blueberries have higher anthocyanin contents than other Manitoba berries
- Analysis, AD, NA
eff↑,
5459- AF,    Auranofin Induces Lethality Driven by Reactive Oxygen Species in High-Grade Serous Ovarian Cancer Cells
- in-vitro, Ovarian, NA
ROS↑, TrxR↓, MMP↓, Apoptosis↑, eff↓, Casp3↑, Casp7↑, DNAdam↑, eff↑, GSH↓, angioG↓, ChemoSen↑, cl‑PARP↑, eff↑,
5460- AF,    Auranofin radiosensitizes tumor cells through targeting thioredoxin reductase and resulting overproduction of reactive oxygen species
- vitro+vivo, Var, 4T1
RadioS↑, ROS↑, eff↓, mt-OCR↓, DNAdam↑, Apoptosis↑, TrxR↓, eff↑,
5469- AF,    Ligand supplementation restores the cancer therapy efficacy of the antirheumatic drug auranofin from serum inactivation
- in-vitro, CRC, HCT116
eff↑, Half-Life↑,
5468- AF,    The gold complex auranofin: new perspectives for cancer therapy
- Review, Var, NA
TrxR↓, ROS↑, eff↑, Apoptosis↑, TumCG↓, TumCP↓, Akt↓, NF-kB↓, DNAdam↑, eff↝, eff↓, PI3K↓, Akt↓, mTOR↓, Hif1a↓, VEGF↓, Casp3↑, CSCs↓, ATP↓, Glycolysis↓, eff↑, eff↑, MMP↓, AIF↑, toxicity↓,
5467- AF,    Auranofin Inhibition of Thioredoxin Reductase Sensitizes Lung Neuroendocrine Tumor Cells (NETs) and Small Cell Lung Cancer (SCLC) Cells to Sorafenib as well as Inhibiting SCLC Xenograft Growth
- in-vitro, Lung, NA
TrxR↓, eff↑, Dose↝, OS↑, eff↑,
1900- AF,    Potential Anticancer Activity of Auranofin
- Review, Var, NA
TrxR↓, ROS↑, Apoptosis↓, TumCP↓, eff↑,
5444- AG,    A Systematic Review of Phytochemistry, Pharmacology and Pharmacokinetics on Astragali Radix: Implications for Astragali Radix as a Personalized Medicine
- Review, Var, NA
*Imm↑, *antiOx↑, *Inflam↓, AntiTum↑, eff↑, chemoP↑, Dose↝, TumCMig↓, TumCP↓, Akt↓, GSK‐3β↓, MMP2↓, MMP9↓, EMT↓, PI3K↓, Akt↓, NF-kB↓, Inflam↓, TGF-β1↓, TNF-α↓, IL6↓, Fas↓, FasL↓, NOTCH1↓, JNK↓, TumCG↓,
5431- AG,    Advances in research on the anti-tumor mechanism of Astragalus polysaccharides
- Review, Var, NA
AntiTum↑, TumCG↓, TumCI↓, Apoptosis↑, Imm↑, Bcl-2↓, BAX↑, Wnt↓, β-catenin/ZEB1↓, TumCG↓, miR-133a-3p↑, JNK↓, Fas↑, P53↑, P21↑, NOTCH1↓, NOTCH3↓, TumCP↓, TumCCA↑, GPx4↓, xCT/SLC7A11↓, AMPK↑, Beclin-1/ATG6↑, NF-kB↓, EMT↓, Vim↓, TumMeta↓, VEGF↓, EGFR↓, eff↑, eff↑, MMP↓, P-gp/ABCB1↓, MMP9↓, ChemoSen↑, SIRT1↓, SREBP1/SREBF1↓, TumAuto↑, PI3K↓, mTOR↓, Casp3↑, Casp9↑, CD133↓, CD44↓, CSCs↓, QoL↑,
5432- AG,    Astragalus polysaccharides combined with radiochemotherapy for cervical cancer: a systematic review and meta-analysis of randomized controlled studies
- Review, Cerv, NA
ChemoSen↑, eff↑, RadioS↑, CEA↓, Wnt↓, β-catenin/ZEB1↓, γH2AX↑, ER Stress↑, mt-TumAuto↑, QoL↑, Imm↑,
5434- AG,    Recent Advances in the Mechanisms and Applications of Astragalus Polysaccharides in Liver Cancer Treatment: An Overview
- Review, Liver, NA
AntiCan↑, Apoptosis↑, TumCP↓, EMT↓, Imm↑, ChemoSen↑, BioAv↓, TumCG↓, IL2↑, IL12↑, TNF-α↑, P-gp/ABCB1↓, MDR1↓, QoL↑, Casp↑, DNAdam↑, Bcl-2↓, BAX↑, MMP↓, Cyt‑c↑, NOTCH1↓, GSK‐3β↓, TumCCA↑, GSH↓, ROS↑, lipid-P↑, c-Iron↑, GPx4↓, ACSL4↑, Ferroptosis↑, Wnt↓, β-catenin/ZEB1↓, cycD1/CCND1↓, Akt↓, PI3K↓, mTOR↓, CXCR4↓, Vim↓, PD-L1↓, eff↑, eff↑, ChemoSen↑, ChemoSen↑, chemoP↑,
5441- AG,  Chemo,    Astragalus-containing Chinese herbal combinations for advanced non-small-cell lung cancer: a meta-analysis of 65 clinical trials enrolling 4751 patients
- Review, Lung, NA
eff↑, ChemoSen↑,
5975- AgNPs,  PDT,  CDT,  RF,    Recent Advances in the Application of Silver Nanoparticles for Enhancing Phototherapy Outcomes
- Review, Var, NA - Review, BPH, NA
ROS↑, EPR↓, eff↑, Bacteria↓, eff↑, eff↑, TumVol↓,
5976- AgNPs,    Review on Harnessing Silver Nanoparticles for Therapeutic Innovations: A Comprehensive Review on Medical Applications, Safety, and Future Directions
- Review, Vit, NA
*Bacteria↓, AntiCan↑, *Inflam↓, *Wound Healing↑, eff↑, ChemoSen↑, EGFR↓, ROS↑, P53↑, BAX↑, Casp3↑, toxicity↝,
5977- AgNPs,  CDT,    Silver Nitroprusside as an Efficient Chemodynamic Therapeutic Agent and a Peroxynitrite nanogenerator for Targeted Cancer Therapy
- in-vivo, Ovarian, A2780S - NA, Ovarian, SKOV3
Fenton↑, ROS↑, eff↑, angioG↓, p‑Akt↓, EPR↑, selectivity↑, selectivity↑, eff↑, Cyt‑c↑, HO-1↑,
4403- AgNPs,    Silver Nanoparticles Decorated UiO-66-NH2 Metal-Organic Framework for Combination Therapy in Cancer Treatment
- in-vitro, GBM, U251 - in-vitro, GBM, U87MG - in-vitro, GBM, GL26 - in-vitro, Cerv, HeLa - in-vitro, CRC, RKO
AntiCan↑, eff↑, EPR↑, selectivity↑, ROS↑, Casp↑, Apoptosis↑, DNAdam↑, tumCV↓, eff↑,
4404- AgNPs,  Rad,    Main Approaches to Enhance Radiosensitization in Cancer Cells by Nanoparticles: A Systematic Review
- Review, Var, NA
eff↑, ROS↑,
4400- AgNPs,  Rad,    Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells
- in-vitro, BC, MCF7 - in-vitro, Nor, MCF10 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, BT549 - in-vivo, BC, MDA-MB-231
ROS↑, DNAdam↑, selectivity↑, TumCG↓, RadioS↑, Dose↝, selectivity↑, other↝, eff↓, eff↑, γH2AX↑, Dose↓, eff↑,
4399- AgNPs,  Chit,    Silver nanoparticles impregnated alginate-chitosan-blended nanocarrier induces apoptosis in human glioblastoma cells
- in-vitro, GBM, U87MG
DNAdam↑, ROS↑, MMP↓, eff↑,
4398- AgNPs,    Induction of apoptosis in cancer cells at low silver nanoparticle concentrations using chitosan nanocarrier
- in-vitro, Colon, HT29
Apoptosis↑, MMP↓, Casp3↑, ROS↑, eff↑,
4415- AgNPs,  SDT,  CUR,    Examining the Impact of Sonodynamic Therapy With Ultrasound Wave in the Presence of Curcumin-Coated Silver Nanoparticles on the Apoptosis of MCF7 Breast Cancer Cells
- in-vitro, BC, MCF7
tumCV↓, BAX↑, Casp3↑, Bcl-2↓, eff↑, ROS↑, sonoS↑, eff↑, MMP↓, Cyt‑c↑,
4413- AgNPs,  Anzaroot,    Green synthesis of silver nanoparticles from plant Astragalus fasciculifolius Bioss and evaluating cytotoxic effects on MCF7 human breast cancer cells
- in-vitro, BC, MCF7
chemoP↑, TumCG↓, eff↑, CellMemb↑, selectivity↑, ROS↑, P53↑,
4412- AgNPs,    Biosynthesis and characterization of silver nanoparticles from Asplenium dalhousiae and their potential biological properties
- in-vitro, CRC, HCT116 - in-vitro, Melanoma, A2780S
Bacteria↓, antiOx↑, AntiCan↑, eff↑,
4405- AgNPs,    Silver nanoparticles defeat p53-positive and p53-negative osteosarcoma cells by triggering mitochondrial stress and apoptosis
- in-vitro, OS, NA
Apoptosis↑, other↑, ROS↑, eff↑, P53↝, Apoptosis↑, cl‑Casp3↑, survivin↓, MMP↓, Cyt‑c↑,
4362- AgNPs,    Enhancing Colorectal Cancer Radiation Therapy Efficacy using Silver Nanoprisms Decorated with Graphene as Radiosensitizers
- in-vitro, CRC, HCT116 - in-vitro, CRC, HT29 - in-vivo, NA, NA
eff↑, TumCG↓, OS↑, RadioS↑, eff↑, ROS↑, DNAdam↑, eff↝,
4358- AgNPs,  HPT,  Rad,    Silver nanocrystals mediated combination therapy of radiation with magnetic hyperthermia on glioma cells
- in-vitro, GBM, U251
RadioS↑, eff↑, TumCD↑,
4379- AgNPs,    Exposure to silver nanoparticles induces size- and dose-dependent oxidative stress and cytotoxicity in human colon carcinoma cells
- in-vitro, CRC, LoVo
eff↑, TumCD↑, ROS↑, Bacteria↓,
4378- AgNPs,    Exploring silver nanoparticles for cancer therapy and diagnosis
- Review, Var, NA
AntiTum↑, ROS↑, eff↑, RadioS↑,
4377- AgNPs,    Interaction between silver nanoparticles of 20 nm (AgNP20 ) and human neutrophils: induction of apoptosis and inhibition of de novo protein synthesis by AgNP20 aggregates
- in-vitro, NA, NA
eff↑, Apoptosis↑,
4376- AgNPs,    Interaction of multi-functional silver nanoparticles with living cells
- in-vitro, Nor, L929 - in-vitro, Lung, A549
eff↑, selectivity↑,
4375- AgNPs,    The cellular uptake and cytotoxic effect of silver nanoparticles on chronic myeloid leukemia cells
- in-vitro, AML, K562
eff↑, ROS↑, Apoptosis↑, eff↓,

Showing Research Papers: 1 to 50 of 987
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 987

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

6IL↑, 1,   ADO↓, 1,   ANAPC2↑, 1,   APE1/APEX1↓, 1,   AURKB↓, 1,   AURKB↑, 1,   Buty↑, 1,   CASP4↑, 1,   CBR1↓, 1,   CD47↓, 1,   CLDN7↑, 1,   compII↓, 1,   compV↓, 1,   DDIT4↑, 1,   DR6↑, 1,   ERCC3↑, 1,   H3K9↓, 3,   HSP60/HSPD1↑, 1,   IL7↓, 1,   Ingr↝, 1,   IRes↓, 1,   IRF1↑, 1,   KAI1/CD82↑, 1,   miR-107↑, 1,   miR-124-3p↓, 1,   miR-224↓, 1,   miR-375↑, 1,   miR-422a↑, 1,   MMP16↓, 1,   MYCN↑, 1,   NA↑, 2,   NPL4↓, 1,   OGFr↑, 1,   OLIG2↓, 1,   ORR↑, 1,   PFS↓, 1,   PFS↑, 1,   PLA2↓, 1,   PSEN1/PS1↓, 1,   PTN↓, 1,   RBC↑, 1,   SCFAs↑, 1,   SUV39H↓, 5,   TFE3↑, 1,   TNFRSF25/DR3/APO3/LARD/TRAMP/WSL1↑, 1,   XRCC1↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 4,   antiOx↑, 21,   antiOx⇅, 1,   ARE/EpRE↑, 1,   ATF3↑, 1,   Catalase↓, 7,   Catalase↑, 5,   compI↓, 5,   CYP1A1↓, 2,   CYP1A1↑, 1,   ENOX2↓, 2,   ENOX2↑, 1,   Fenton↑, 14,   Ferroptosis↓, 2,   Ferroptosis↑, 29,   frataxin↑, 1,   GPx↓, 6,   GPx↑, 5,   GPx4↓, 9,   GPx4↑, 1,   GSH↓, 49,   GSH↑, 2,   GSH↝, 1,   i-GSH∅, 1,   mt-GSH↓, 1,   GSH/GSSG↓, 5,   GSR↓, 1,   GSR↑, 1,   GSSG↑, 1,   ox-GSSG↑, 1,   GSTP1/GSTπ↓, 3,   GSTs↓, 1,   GSTZ1↓, 1,   H2O2↑, 14,   e-H2O2↓, 1,   i-H2O2∅, 1,   HK1↓, 1,   HO-1↓, 9,   HO-1↑, 16,   HO-2↓, 1,   hyperG↓, 1,   ICD↑, 5,   Iron↓, 1,   Iron↑, 8,   i-Iron↑, 2,   c-Iron↑, 1,   IRP1↑, 1,   Keap1↓, 1,   Keap1↑, 1,   lipid-P?, 1,   lipid-P↓, 5,   lipid-P↑, 25,   MDA↓, 3,   MDA↑, 6,   Mets↑, 1,   MFN2↑, 1,   NADH↑, 1,   NADHdeh?, 1,   NAF1↓, 1,   NQO1↑, 4,   Nrf1↑, 1,   NRF2↓, 14,   NRF2↑, 24,   NRF2⇅, 1,   NRF2↝, 1,   NRF2∅, 1,   OXPHOS↓, 11,   OXPHOS↑, 5,   OXPHOS↝, 3,   mt-OXPHOS↑, 2,   PARK2↑, 3,   Prx↓, 1,   Prx3↑, 1,   Prx4↑, 1,   Prx6↑, 1,   PrxI↓, 1,   PrxII↓, 1,   PYCR1↓, 2,   ROS?, 2,   ROS↓, 27,   ROS↑, 388,   ROS⇅, 8,   ROS↝, 2,   ROS∅, 1,   i-ROS↓, 1,   i-ROS↑, 1,   mt-ROS↑, 9,   RPM↑, 1,   SIRT3↓, 1,   SIRT3↑, 3,   SOD↓, 10,   SOD↑, 7,   SOD1↓, 2,   SOD1↑, 1,   Thiols↓, 1,   Trx↓, 5,   Trx1↓, 1,   Trx2↓, 2,   TrxR↓, 23,   TrxR1?, 1,   TrxR1↓, 4,   TrxR1⇅, 1,   TrxR2↓, 1,   xCT/SLC7A11↓, 6,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 4,   IronCh↑, 2,   KLF5↓, 1,   Tf↓, 1,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ABL1↓, 1,   ADP:ATP↑, 2,   AIF↑, 6,   ATP↓, 37,   ATP↑, 1,   ATP∅, 1,   mt-ATP↓, 1,   BCR-ABL↓, 1,   CDC2↓, 3,   CDC25↓, 4,   CDC25↑, 1,   compIII↓, 2,   compIII↑, 1,   EGF↓, 3,   ETC↓, 6,   ETC↑, 1,   ETC↝, 1,   FGFR1↓, 1,   Insulin↓, 6,   MEK↓, 5,   p‑MEK↓, 1,   mitResp↓, 3,   mitResp↑, 4,   MKK4↓, 1,   MKK7↓, 1,   MMP↓, 133,   MMP↑, 3,   Mortalin↓, 1,   MPT↑, 13,   mtDam↑, 30,   OCR↓, 8,   OCR↑, 2,   mt-OCR↓, 1,   PGC-1α↑, 2,   PINK1↑, 3,   Raf↓, 4,   c-Raf↓, 1,   SDH↓, 2,   XIAP↓, 21,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

12LOX?, 1,   12LOX↓, 2,   ACC↑, 3,   ACLY↓, 11,   p‑ACLY↓, 1,   ACSL4↑, 4,   adiP↑, 1,   AKT1↓, 1,   ALAT↓, 6,   ALAT↑, 1,   ALDOA↓, 1,   AMP↑, 2,   AMPK↑, 29,   ATG7↑, 2,   CAIX/CA9↓, 2,   CAIX/CA9↑, 1,   citrate↓, 2,   cMyc↓, 36,   cMyc↑, 1,   CPT1A↓, 1,   CREB↑, 1,   CRM↑, 1,   CYP3A4↓, 1,   ECAR↓, 3,   ECAR↝, 1,   ECAR∅, 1,   ENO1↓, 1,   FABP4↓, 1,   FAO↑, 1,   FASN↓, 6,   FASN↑, 2,   FBPase↑, 1,   FGF21↓, 1,   GAPDH↓, 3,   GLS↓, 1,   glucoNG↓, 1,   glucoNG↑, 1,   glucose↓, 1,   glucose↑, 1,   glucose↝, 1,   glucose∅, 1,   GlucoseCon↓, 12,   GlucoseCon↑, 2,   GlutMet↓, 1,   glyC↓, 1,   Glycolysis↓, 54,   Glycolysis↑, 3,   Glycolysis↝, 1,   Histones↝, 1,   HK2?, 1,   HK2↓, 23,   HK2∅, 1,   HMG-CoA↓, 10,   KeyT↑, 1,   lactateProd↓, 23,   lactateProd↑, 4,   LAT↓, 1,   LDH↓, 14,   LDH↑, 3,   p‑LDH↓, 1,   i-LDH↓, 1,   LDHA↓, 13,   LDHA∅, 1,   LDL↓, 7,   lipidLev↑, 1,   lipoGen↓, 3,   MCT4↓, 1,   MCU↓, 1,   NADH:NAD↓, 1,   NADPH↓, 5,   NADPH↑, 2,   PDH↓, 3,   PDH↑, 5,   p‑PDH↓, 1,   p‑PDH↑, 1,   PDHB↓, 1,   PDK1 / PDPK1?, 2,   PDK1 / PDPK1↓, 13,   PDK3↑, 1,   PDKs↓, 12,   PFK↓, 5,   PFK1↓, 2,   PFK2?, 1,   PFK2↓, 1,   PFKFB2↓, 1,   PFKP↓, 1,   PGK1↓, 1,   PGM1↓, 1,   PGM1∅, 1,   PI3K/Akt↓, 1,   PI3K/mTOR/ETS2↓, 1,   PIK3CA↓, 1,   PIK3CA↑, 1,   PKM2↓, 20,   PKM2↑, 1,   p‑PKM2↓, 1,   POLD1↓, 1,   polyA↓, 1,   PPARα↓, 2,   PPARγ↓, 1,   PPARγ↑, 4,   PPP↑, 1,   PSMB5↓, 1,   p‑S6K↓, 1,   SCD1↓, 3,   SIRT1↓, 6,   SIRT1↑, 5,   SIRT2↓, 2,   SREBP1/SREBF1↓, 1,   SREBP2↓, 3,   STK11/LKB1↑, 1,   TCA?, 1,   TCA↓, 3,   TCA↑, 2,   TS↓, 2,   Warburg↓, 16,   Warburg↑, 1,   β-oxidation↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 120,   Akt↑, 12,   p‑Akt↓, 32,   p‑Akt↑, 2,   APAF1↑, 4,   Apoptosis?, 2,   Apoptosis↓, 11,   Apoptosis↑, 270,   mt-Apoptosis↑, 3,   ASK1↑, 2,   aSmase↑, 1,   BAD↑, 8,   BAD↝, 1,   Bak↑, 10,   BAX↓, 4,   BAX↑, 113,   BAX↝, 2,   Bax:Bcl2↑, 27,   Bcl-2↓, 128,   Bcl-2↑, 4,   Bcl-2↝, 1,   Bcl-2∅, 1,   Bcl-xL↓, 29,   Bcl-xL↑, 4,   BID↓, 1,   BID↑, 2,   p‑BID↓, 1,   cl‑BID↑, 2,   BIM↑, 8,   Casp↑, 40,   Casp↝, 1,   Casp1↑, 1,   Casp12?, 1,   pro‑Casp12↓, 1,   Casp2↑, 3,   Casp3↓, 5,   Casp3↑, 148,   cl‑Casp3↑, 24,   cl‑Casp3⇅, 1,   cl‑Casp3∅, 1,   proCasp3↓, 1,   proCasp3↑, 2,   pro‑Casp3↑, 1,   Casp7↑, 15,   cl‑Casp7↑, 4,   Casp8↓, 3,   Casp8↑, 23,   cl‑Casp8↑, 6,   proCasp8↑, 3,   pro‑Casp8↑, 1,   Casp9↓, 1,   Casp9↑, 84,   cl‑Casp9↑, 12,   proCasp9↑, 2,   CBP↓, 1,   cFLIP↓, 2,   Chk2↓, 1,   CK2↓, 4,   Cupro↑, 3,   Cyt‑c↑, 82,   Cyt‑c↝, 1,   Diablo↑, 6,   DR4↑, 6,   DR5↑, 17,   FADD↑, 3,   Fap1↓, 1,   Fas↓, 2,   Fas↑, 15,   FasL↓, 1,   FasL↑, 8,   FasL⇅, 1,   Ferroptosis↓, 2,   Ferroptosis↑, 29,   GSDMD↑, 2,   GSDME↑, 1,   cl‑GSDME↑, 1,   GSDME-N↑, 1,   HEY1↓, 1,   HGF/c-Met↓, 1,   Hippo↓, 1,   Hippo↝, 1,   hTERT/TERT↓, 12,   IAP1↓, 7,   IAP2/BIRC3↓, 2,   cl‑IAP2/BIRC3↑, 1,   iNOS↓, 13,   iNOS↑, 2,   JNK↓, 9,   JNK↑, 20,   p‑JNK↓, 3,   p‑JNK↑, 5,   lysoMP↓, 1,   lysoMP↑, 1,   MAPK↓, 20,   MAPK↑, 14,   MAPK↝, 1,   p‑MAPK↓, 1,   p‑MAPK↑, 3,   Mcl-1↓, 30,   Mcl-1↑, 1,   p‑Mcl-1↓, 1,   cl‑Mcl-1↑, 1,   MDM2↓, 9,   MLKL↑, 1,   p‑MLKL↓, 1,   MOMP↓, 2,   MOMP↑, 2,   Myc↓, 8,   Myc↑, 1,   Necroptosis↑, 4,   necrosis↑, 6,   NOXA↑, 4,   p27/CDKN1B↓, 2,   p27/CDKN1B↑, 17,   p38↓, 4,   p38↑, 15,   p‑p38↓, 2,   p‑p38↑, 7,   Paraptosis↑, 3,   Proteasome?, 1,   Proteasome↓, 4,   PUMA↑, 7,   Pyro↑, 7,   SK↓, 1,   survivin↓, 52,   Telomerase↓, 11,   TRAIL↑, 3,   TRPV1↑, 4,   TumCD↓, 2,   TumCD↑, 41,   TumCD∅, 2,   TUNEL↑, 1,   YAP/TEAD↓, 6,   YAP/TEAD↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

AMPKα↑, 3,   CaMKII ↑, 1,   cSrc↓, 2,   EF-1α↓, 1,   FOXD3↑, 1,   HCAR2↑, 1,   HER2/EBBR2↓, 9,   miR-25-5p↓, 1,   p70S6↓, 1,   SOX9?, 1,   SOX9↓, 2,   Sp1/3/4↓, 10,   TRPV2↑, 1,   TSC2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   ChrMod↑, 1,   ChrMod↝, 1,   cJun↓, 8,   cJun↑, 3,   p‑cJun↑, 1,   EZH2↓, 3,   H3↓, 1,   H3↑, 2,   p‑H3↓, 1,   ac‑H3↓, 1,   ac‑H3↑, 3,   H3K4↓, 1,   H4↑, 1,   ac‑H4↓, 1,   ac‑H4↑, 3,   HATs↓, 4,   HATs↑, 1,   miR-21↓, 3,   miR-218↑, 1,   miR-27a-3p↓, 1,   miR-30a-5p↑, 2,   other?, 4,   other↓, 8,   other↑, 21,   other↝, 41,   other∅, 1,   PCAF↓, 1,   PhotoS↑, 4,   pRB↓, 1,   p‑pRB↓, 2,   SD↑, 1,   sonoS↑, 3,   tumCV↓, 70,   tumCV↑, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↑, 1,   CHOP/DDIT3↓, 1,   CHOP/DDIT3↑, 21,   cl‑CHOP/DDIT3↑, 1,   e-CRT↑, 1,   eIF2α↓, 1,   eIF2α↑, 4,   p‑eIF2α↓, 1,   p‑eIF2α↑, 4,   ER Stress↓, 2,   ER Stress↑, 64,   GRP78/BiP?, 1,   GRP78/BiP↓, 6,   GRP78/BiP↑, 15,   GRP78/BiP↝, 1,   GRP94↑, 1,   HSP27↓, 5,   HSP27↑, 1,   HSP70/HSPA5↓, 7,   HSP70/HSPA5↑, 5,   e-HSP70/HSPA5↑, 1,   HSP72↑, 1,   HSP90↓, 14,   HSP90↑, 1,   e-HSP90↑, 2,   ac‑HSP90↑, 1,   HSPs↓, 1,   HSPs↑, 3,   HSPs∅, 1,   IRE1↑, 5,   PERK↑, 7,   p‑PERK↓, 1,   UPR↓, 1,   UPR↑, 14,   XBP-1↓, 1,   XBP-1↑, 4,   XBP-1↝, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

APA↑, 1,   ATG3↓, 1,   ATG3↑, 1,   ATG5↑, 5,   autoF↓, 1,   Beclin-1/ATG6↓, 2,   Beclin-1/ATG6↑, 12,   p‑Beclin-1/ATG6↑, 1,   BNIP3?, 1,   BNIP3↑, 2,   LAMP2↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 2,   LC3B↑, 2,   LC3II↓, 1,   LC3II↑, 18,   LC3s↓, 1,   lysosome↓, 1,   MitoP↑, 3,   p62↓, 9,   p62↑, 7,   p‑p62↑, 1,   SESN2↑, 3,   TumAuto↓, 1,   TumAuto↑, 62,   TumAuto⇅, 2,   TumAuto↝, 1,   mt-TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

ATM↓, 1,   ATM↑, 2,   BRCA1↓, 2,   p‑BRCA1↑, 1,   BRCA2↓, 2,   CHK1↓, 1,   p‑CHK1↑, 1,   DNA-PK↑, 2,   DNAdam↓, 2,   DNAdam↑, 84,   mt-DNAdam↑, 1,   DNArepair↓, 4,   DNArepair↑, 1,   DNMT1↓, 9,   DNMT3A↓, 3,   DNMT3B↓, 1,   DNMTs↓, 8,   m-FAM72A↓, 1,   GADD45A↑, 2,   MDMX↓, 1,   MGMT↓, 1,   NKX3.1↓, 2,   p16↑, 2,   P53↓, 5,   P53↑, 61,   P53↝, 2,   p‑P53↓, 1,   p‑P53↑, 4,   p53 Wildtype↓, 1,   PARP↓, 4,   PARP↑, 14,   p‑PARP↑, 1,   cl‑PARP↓, 1,   cl‑PARP↑, 69,   cl‑PARP↝, 1,   cl‑PARP∅, 1,   PARP1↑, 1,   cl‑PARP1↑, 1,   PCNA↓, 18,   SIRT6↓, 2,   SIRT6↑, 1,   TP53↓, 2,   TP53↑, 3,   γH2AX↑, 9,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1?, 1,   CDK1↓, 11,   p‑CDK1↓, 1,   CDK2↓, 25,   p‑CDK2↓, 1,   CDK4↓, 39,   CDK4↑, 3,   p‑CDK4↓, 1,   Cyc↓, 1,   cycA1/CCNA1↓, 7,   CycB/CCNB1↓, 15,   CycB/CCNB1↑, 2,   cycD1/CCND1↓, 62,   p‑cycD1/CCND1↓, 1,   CycD3↓, 3,   CycD3↑, 1,   cycE/CCNE↓, 18,   cycE/CCNE↑, 1,   cycE1↓, 1,   cycF↑, 1,   E2Fs↓, 3,   mitA↑, 1,   P21?, 2,   P21↓, 3,   P21↑, 51,   PLK1↓, 1,   RB1↑, 2,   p‑RB1↓, 6,   Securin↓, 1,   TumCCA?, 1,   TumCCA↓, 6,   TumCCA↑, 187,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 9,   ALDH1A1↓, 4,   AR-FL↓, 1,   AR-V7↑, 1,   CD133↓, 8,   CD133↑, 1,   CD24↓, 1,   CD44↓, 10,   cDC2↓, 1,   CDK8↓, 1,   cFos↓, 8,   cMET↓, 1,   cMYB↓, 2,   CSCs↓, 58,   CSCs↑, 2,   CSCsMark↓, 2,   CTSB↓, 1,   CTSD↓, 1,   CTSL↑, 1,   Diff↓, 2,   Diff↑, 9,   EMT↓, 63,   EMT↑, 3,   EpCAM↓, 1,   ERK↓, 32,   ERK↑, 9,   ERK↝, 1,   p‑ERK↓, 17,   p‑ERK↑, 2,   FGF↓, 1,   FOXM1↓, 3,   FOXO↑, 1,   FOXO1↓, 2,   FOXO1↑, 2,   FOXO3↓, 3,   FOXO3↑, 7,   FOXO4↓, 1,   FOXO4↑, 1,   Gli↓, 1,   Gli1↓, 11,   GSK‐3β↓, 12,   GSK‐3β↑, 5,   p‑GSK‐3β↓, 3,   p‑GSK‐3β↑, 1,   H3K27ac∅, 1,   HDAC↓, 34,   HDAC1↓, 3,   HDAC10↑, 1,   HDAC2↓, 4,   HDAC3↓, 3,   HDAC8↓, 2,   HH↓, 13,   HMGCR↓, 2,   HMGCR↑, 1,   HMGCR⇅, 1,   HMTs↓, 1,   IGF-1↓, 15,   IGF-1↑, 1,   IGF-1↝, 1,   IGF-1∅, 1,   IGF-1R↓, 5,   IGF-1R↑, 1,   p‑IGF-1R↓, 1,   IGF-2↓, 1,   IGFBP1↓, 1,   IGFBP1↑, 4,   IGFBP3↑, 3,   IGFR↓, 2,   KLF4↓, 1,   Let-7↑, 2,   LRP6↓, 1,   p‑MAP2K1/MEK1↓, 1,   miR-34a↓, 1,   miR-34a↑, 2,   mTOR↓, 69,   mTOR↑, 2,   mTOR⇅, 1,   mTOR↝, 1,   p‑mTOR↓, 7,   mTORC1↓, 4,   p‑mTORC1↓, 1,   mTORC2↓, 1,   n-MYC↓, 2,   Nanog↓, 14,   Nestin↓, 3,   NOTCH↓, 8,   NOTCH1↓, 12,   NOTCH1↑, 4,   NOTCH3↓, 4,   OCT4↓, 13,   p300↓, 2,   P70S6K↓, 4,   p‑P70S6K↓, 2,   P90RSK↓, 1,   PI3K↓, 91,   PI3K↑, 5,   p‑PI3K↓, 4,   PTCH1↓, 4,   PTCH2↓, 1,   PTEN↑, 21,   p‑PTEN↓, 1,   RAS↓, 8,   SAL↑, 1,   Shh↓, 6,   SHP1↑, 2,   Smo↓, 5,   SOX2↓, 7,   Src↓, 3,   p‑Src↓, 1,   STAT↓, 5,   STAT1↓, 1,   STAT3↓, 64,   STAT3↑, 2,   STAT3⇅, 1,   STAT3↝, 2,   p‑STAT3↓, 13,   p‑STAT3↑, 4,   mt-STAT3↓, 1,   STAT5↓, 1,   STAT6↓, 4,   TCF↓, 3,   TCF↑, 1,   TCF-4↓, 2,   TOP1↓, 6,   TOP2↓, 3,   TOP2↑, 1,   TRPM7↓, 3,   TumCG↓, 142,   TumCG↑, 3,   TumCG↝, 1,   tyrosinase↓, 1,   VDR↑, 1,   VGCC↑, 1,   VGSC↑, 1,   Wnt?, 1,   Wnt↓, 36,   Wnt↑, 2,   Wnt/(β-catenin)↓, 3,  

Migration(tgid=13) ⓘ

5LO↓, 7,   Akt2↓, 1,   annexin II↓, 1,   AntiAg?, 1,   AntiAg↓, 1,   AntiAg↑, 5,   AP-1↓, 10,   ATPase↓, 1,   AXL↓, 2,   BACH1↓, 1,   Ca+2↓, 6,   Ca+2↑, 36,   Ca+2↝, 2,   i-Ca+2?, 1,   i-Ca+2↓, 1,   i-Ca+2↑, 1,   CAFs/TAFs↓, 2,   cal2↑, 1,   CC(CDKs/cyclins)↓, 1,   CD11b↑, 2,   CD31/PECAM-1↓, 1,   Cdc42↓, 1,   Cdc42↑, 1,   CDKN1C/p57↑, 1,   CEA↓, 1,   Chl↑, 1,   CLDN1↓, 4,   CLDN1↑, 1,   CLDN2↓, 2,   CLDN2↑, 1,   Cofilin↓, 1,   CXCL12↓, 2,   E-cadherin↓, 3,   E-cadherin↑, 35,   ER-α36↓, 3,   F-actin↓, 1,   FAK↓, 9,   p‑FAK↓, 3,   p‑FAK↑, 1,   fascin↓, 2,   Fibronectin↓, 5,   GLI2↓, 4,   hnRNPA1↓, 1,   ITGA1∅, 1,   ITGA5∅, 1,   ITGB1↓, 1,   ITGB1∅, 1,   ITGB3↓, 1,   ITGB3∅, 1,   ITGB4↓, 1,   ITGB4∅, 1,   Ki-67↓, 30,   Ki-67↑, 1,   KLF2↓, 1,   KRAS↓, 3,   L-sel↑, 1,   LAMs↓, 2,   LEF1↓, 2,   MALAT1↓, 3,   MET↓, 2,   miR-133a-3p↑, 1,   miR-139-5p↑, 1,   miR-155↓, 2,   miR-200b↑, 1,   miR-200c↑, 2,   miR-29b↓, 1,   miR-29b↑, 1,   miR-340↓, 1,   miR-384↑, 1,   MMP-10↓, 1,   MMP1↓, 6,   MMP13↓, 2,   MMP15↓, 1,   MMP2↓, 59,   MMP2↑, 1,   MMP2⇅, 1,   MMP2∅, 1,   MMP3↓, 4,   MMP7↓, 10,   MMP9↓, 77,   MMP9↑, 3,   MMP9⇅, 1,   MMP9∅, 1,   MMPs↓, 26,   MUC1↑, 1,   MUC4↓, 1,   N-cadherin↓, 21,   NEDD9↓, 1,   p‑p44↓, 1,   PAK1↓, 3,   PDGF↓, 3,   PKA↓, 2,   PKA↑, 1,   PKCδ↓, 7,   RECK↑, 1,   Rho↓, 4,   RIP3↑, 1,   p‑RIP3↑, 1,   ROCK1↓, 4,   Slug↓, 10,   Smad1↓, 3,   SMAD2↓, 1,   SMAD3↓, 3,   Snail?, 1,   Snail↓, 21,   SOX4↓, 2,   SOX4↑, 1,   STAC2↓, 1,   TET1↑, 4,   TGF-β↓, 14,   TGF-β↑, 1,   TGF-β1↓, 3,   TIMP1↓, 1,   TIMP1↑, 5,   TIMP2↓, 1,   TIMP2↑, 7,   TJ↓, 1,   TJ↑, 1,   Treg lymp↓, 2,   TRIB3↑, 2,   TSC1↑, 1,   TSP-1↑, 3,   TumCA↓, 3,   TumCI↓, 82,   TumCI↑, 1,   TumCMig↓, 61,   TumCMig↑, 3,   TumCP?, 1,   TumCP↓, 166,   TumCP↑, 6,   TumCP∅, 2,   TumMeta↓, 80,   TumMeta↑, 5,   TumPF↓, 1,   Twist↓, 10,   uPA↓, 12,   uPAR↓, 2,   VCAM-1↓, 1,   VEGFR1↓, 2,   Vim?, 1,   Vim↓, 28,   Zeb1↓, 13,   Zeb1↑, 1,   ZEB2↓, 2,   ZO-1↑, 3,   α-SMA↓, 1,   α-tubulin↓, 1,   β-catenin/ZEB1↓, 44,   β-catenin/ZEB1↑, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 99,   angioG↑, 5,   ATF4↓, 1,   ATF4↑, 9,   ATF4↝, 1,   ECM/TCF↓, 1,   EGFR↓, 29,   p‑EGFR↓, 1,   Endoglin↑, 1,   eNOS↓, 2,   eNOS↑, 1,   EPR↓, 1,   EPR↑, 19,   EPR↝, 1,   HIF-1↓, 4,   Hif1a↓, 54,   Hif1a↑, 2,   Hypoxia↓, 2,   miR-126↑, 1,   NO↓, 4,   NO↑, 4,   PDGFR-BB↓, 2,   p‑PDGFR-BB↓, 1,   PHDs↓, 1,   TAMS↑, 1,   VEGF↓, 85,   VEGFR2/KDR/Flk1↓, 8,   ZBTB10↑, 1,  

Barriers & Transport(tgid=15) ⓘ

AQPs↓, 1,   BBB↑, 8,   BBB∅, 2,   CellMemb↑, 5,   CTR1↑, 1,   GLUT1↓, 11,   GLUT1↑, 1,   GLUT3↓, 1,   GLUT3↑, 1,   GLUT4↓, 3,   IBI↑, 2,   NHE1↓, 1,   OCLN↑, 1,   P-gp/ABCB1↓, 21,   P-gp/ABCB1↝, 1,   P-gp/ABCB1∅, 1,   SMCT1∅, 1,   sonoP↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CCR7↓, 1,   CD14↓, 1,   CD4+↓, 1,   CD4+↑, 2,   COX1↓, 5,   COX2/PTGS2↓, 69,   COX2/PTGS2↑, 3,   CR3↝, 1,   CRP↓, 1,   CXCR4↓, 14,   DCells↑, 1,   Dectin1↝, 1,   FOXP3↓, 1,   Gal1↑, 1,   HCAR2↑, 1,   HMGB1↓, 3,   e-HMGB1↑, 1,   ICAM-1↓, 1,   IFN-γ↓, 2,   IFN-γ↑, 7,   Igs↑, 1,   IKKα↓, 5,   IL1↓, 3,   IL1↑, 3,   IL10↓, 5,   IL10↑, 4,   IL12↓, 1,   IL12↑, 3,   IL17↑, 1,   IL1α↓, 1,   IL1β↓, 12,   IL1β↑, 2,   IL2↓, 2,   IL2↑, 8,   IL4↓, 3,   IL4↑, 1,   IL6↓, 35,   IL6↑, 1,   IL8↓, 7,   IL8↑, 1,   Imm↑, 41,   Imm↝, 5,   INF-γ↑, 1,   Inflam↓, 36,   IκB↑, 3,   p‑IκB↓, 1,   JAK↓, 4,   JAK1↓, 3,   JAK2↓, 9,   pol-M1↝, 1,   M2 MC↓, 4,   MCP1/CCL2↓, 5,   MIP2↓, 1,   MyD88↑, 1,   Neut↓, 1,   NF-kB↓, 113,   NF-kB↑, 7,   NF-kB↝, 1,   p‑NF-kB↓, 1,   NK cell↑, 19,   p65↓, 7,   ac‑p65↓, 1,   PD-1↓, 3,   PD-L1↓, 13,   PD-L1↑, 4,   PGE1↓, 1,   PGE2↓, 21,   PSA↓, 11,   PSA∅, 1,   RANTES↓, 1,   SOCS1↑, 1,   T-Cell↑, 5,   T-Cell↝, 1,   Th1 response↑, 3,   Th2↑, 1,   TLR2↓, 1,   TLR4↓, 4,   TLR4↑, 1,   TNF-α↓, 26,   TNF-α↑, 5,  

Cellular Microenvironment(tgid=17) ⓘ

cGAS–STING↑, 1,   pH↓, 3,   pH↑, 6,   pH↝, 2,   pH∅, 1,   e-pH↓, 1,   e-pH↑, 8,   i-pH↓, 1,   Temp↓, 1,   TIM-3↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↓, 3,  

Protein Aggregation(tgid=19) ⓘ

NLRP3↓, 2,   NLRP3↑, 1,   PP2A↑, 1,   XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

ACTH↓, 1,   AR↓, 18,   AR↑, 1,   CDK6↓, 13,   CDK6↑, 5,   COMT↓, 2,   CYP11A1↓, 1,   CYP19↓, 2,   CYP24A1↓, 1,   ERα/ESR1↓, 1,   EstroRS/ERS↑, 1,   FKBP5↓, 1,   GR↓, 1,   GR↑, 1,   RANKL↓, 1,   SXR↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABC↓, 1,   BioAv↓, 46,   BioAv↑, 86,   BioAv↝, 18,   BioEnh?, 1,   BioEnh↑, 7,   chemoR↓, 2,   ChemoSen↓, 4,   ChemoSen↑, 219,   ChemoSen⇅, 2,   ChemoSen↝, 1,   CYP1A2↓, 1,   CYP2C9↓, 1,   DDS↑, 10,   Dose?, 9,   Dose↓, 6,   Dose↑, 23,   Dose⇅, 1,   Dose↝, 138,   Dose∅, 34,   DrugR↓, 1,   eff?, 2,   eff↓, 100,   eff↑, 1285,   eff⇅, 1,   eff↝, 39,   eff∅, 4,   Half-Life↓, 13,   Half-Life↑, 12,   Half-Life↝, 15,   Half-Life∅, 2,   MDR1↓, 10,   MRP1/ABCC1↓, 2,   P450↓, 3,   RadioS↑, 88,   RadioS∅, 1,   selectivity?, 3,   selectivity↓, 3,   selectivity↑, 168,   selectivity↝, 1,   TET2↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

AFP↓, 2,   ALAT↓, 6,   ALAT↑, 1,   ALP↓, 4,   AR↓, 18,   AR↑, 1,   ascitic↓, 1,   AST↓, 4,   AST↑, 1,   BG↓, 6,   BMD↑, 2,   BP↓, 1,   BRCA1↓, 2,   p‑BRCA1↑, 1,   CA125↓, 1,   CA19-9↓, 1,   CEA↓, 1,   CRP↓, 1,   E6↓, 3,   E7↓, 3,   EGFR↓, 29,   p‑EGFR↓, 1,   ERα/ESR1↓, 1,   EstroRS/ERS↑, 1,   EZH2↓, 3,   Ferritin↓, 4,   FOXM1↓, 3,   GutMicro↑, 15,   GutMicro↝, 2,   Hcy/homoC↓, 1,   Hcy/homoC↝, 1,   HER2/EBBR2↓, 9,   HOMA↓, 1,   hTERT/TERT↓, 12,   IL6↓, 35,   IL6↑, 1,   Ki-67↓, 30,   Ki-67↑, 1,   KRAS↓, 3,   LDH↓, 14,   LDH↑, 3,   p‑LDH↓, 1,   i-LDH↓, 1,   Myc↓, 8,   Myc↑, 1,   NOS2↓, 1,   PD-L1↓, 13,   PD-L1↑, 4,   PSA↓, 11,   PSA∅, 1,   TG/TAG↓, 1,   TP53↓, 2,   TP53↑, 3,   TRIB3↑, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↓, 4,   AntiCan↑, 73,   AntiCan?, 1,   AntiCan∅, 1,   AntiDiabetic↑, 1,   antiNeop↑, 5,   AntiTum↓, 3,   AntiTum↑, 37,   cachexia↓, 1,   cardioP↑, 10,   CardioT↓, 3,   CardioT↑, 1,   chemoP↑, 38,   chemoPv↑, 15,   ChemoSideEff↓, 20,   cognitive↑, 2,   fatigue↓, 2,   hepatoP↓, 2,   hepatoP↑, 7,   memory↑, 2,   MusCon↓, 2,   NDRG1↑, 1,   neuroP↑, 10,   NP/CIPN↓, 3,   NP/CIPN↑, 1,   NP/CIPN↝, 1,   OS?, 1,   OS↓, 1,   OS↑, 65,   OS∅, 1,   PARP16↓, 1,   PDE4↓, 1,   Pin1↓, 2,   QoL↑, 16,   QoL∅, 3,   radioP↑, 15,   Remission↑, 7,   RenoP↑, 5,   Risk↓, 35,   Risk↑, 2,   Risk∅, 2,   Strength∅, 1,   toxicity↓, 53,   toxicity↑, 10,   toxicity⇅, 1,   toxicity↝, 24,   toxicity∅, 9,   TumVol↓, 42,   TumW↓, 18,   UBE2C↓, 1,   Weight↑, 6,   Weight∅, 2,   Wound Healing↑, 3,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 4,   CD8+↑, 10,   Dectin1↝, 1,   Sepsis↓, 2,  
Total Targets: 1233

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiBio↑, 5,   compII↑, 1,   CYP2C19↓, 1,   CYP2C8↓, 1,   CYP2D6↓, 1,   diuretic↑, 3,   NLR↓, 1,   Stroke↓, 3,   TRPA1↑, 1,   β-HEX↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx?, 1,   antiOx↓, 9,   antiOx↑, 74,   mt-antiOx↑, 1,   ARE↑, 1,   Catalase↑, 30,   Copper↓, 1,   CoQ10↑, 1,   CYP1A1↓, 1,   CYP2E1↓, 1,   Fenton↓, 1,   Ferroptosis↓, 2,   GPx↑, 26,   GPx1↑, 1,   GPx4↑, 2,   GSH↓, 1,   GSH↑, 31,   GSR↑, 2,   GSSG∅, 1,   GSTA1↓, 1,   GSTs↑, 7,   H2O2↓, 3,   H2O2↑, 1,   HDL↓, 1,   HDL↑, 1,   HDL∅, 1,   HO-1↓, 2,   HO-1↑, 22,   Iron↓, 1,   i-Iron↓, 1,   Keap1↓, 2,   Keap1↝, 1,   lipid-P↓, 22,   mt-lipid-P↓, 1,   MDA↓, 17,   MDA↑, 1,   Mets↝, 1,   MPO↓, 4,   MPO↑, 1,   NQO1↑, 3,   Nrf1↑, 1,   NRF2↑, 39,   OXPHOS↑, 1,   Prx↑, 1,   RNS↓, 1,   ROS?, 2,   ROS↓, 84,   ROS↑, 1,   ROS↝, 1,   ROS∅, 5,   mt-ROS?, 1,   selenoP↑, 3,   SOD↑, 34,   SOD1↑, 2,   SOD2↑, 1,   TAC↑, 5,   Trx↑, 1,   VitC↑, 3,   VitE↑, 1,   xCT/SLC7A11↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,   IronCh↝, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↓, 1,   ATP↓, 1,   ATP↑, 6,   compIII↑, 1,   ETC↑, 1,   Insulin↑, 2,   mitResp↑, 2,   MMP↓, 1,   MMP↑, 4,   MMP∅, 1,   mtDam↓, 1,   OCR↑, 1,   PGC-1α↑, 2,   PGC-1α↝, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACC↓, 1,   ALAT↓, 6,   AMPK↓, 2,   AMPK↑, 5,   p‑cMyc↑, 1,   CYP3A4↓, 1,   cytoP450↓, 1,   ECAR↓, 1,   mt-FAO↑, 1,   FASN↓, 1,   glucose↓, 7,   GlucoseCon↑, 3,   GLUT2↑, 1,   Glycolysis↓, 1,   KeyT↑, 1,   LDH↓, 3,   LDL↓, 5,   lipidLev↓, 1,   NAD↓, 1,   NAD↑, 1,   NADH:NAD↑, 1,   NADPH↓, 2,   NADPH↑, 2,   NH3↓, 1,   PPARγ↓, 2,   PPARγ↑, 2,   p‑PPARγ↓, 1,   SIRT1↑, 4,  

Cell Death(tgid=5) ⓘ

Akt↓, 4,   Akt↑, 2,   Apoptosis↓, 4,   ASK1↓, 1,   BAX↓, 3,   BAX↑, 1,   Bax:Bcl2↓, 1,   Bcl-2↓, 1,   Bcl-2↑, 1,   Bcl-xL↓, 1,   Casp12↓, 1,   Casp3?, 1,   Casp3↓, 6,   Casp3∅, 1,   cl‑Casp8↑, 1,   Casp9↓, 2,   Cyt‑c↓, 2,   Cyt‑c↑, 1,   Cyt‑c∅, 2,   Fas↓, 1,   FasL↓, 1,   Ferroptosis↓, 2,   GADD34↓, 1,   GranB/GZMB↓, 1,   iNOS↓, 7,   JNK↓, 3,   JNK↑, 1,   p‑JNK↓, 1,   MAPK↓, 6,   MAPK↑, 2,   p38↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

HCAR2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 3,   other↑, 1,   other↝, 11,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 2,   CHOP/DDIT3↑, 1,   p‑eIF2α↓, 1,   cl‑eIF2α↑, 1,   ER Stress↓, 5,   GRP78/BiP↓, 1,   GRP78/BiP↑, 1,   HSP70/HSPA5↓, 1,   HSP70/HSPA5↝, 1,   HSPs↑, 1,   p‑PERK↑, 1,   UPR↓, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,   Beclin-1/ATG6↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3II↓, 1,   LC3II↑, 1,   MitoP↑, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 6,   GADD45A↑, 1,   P53↓, 1,   P53↑, 1,   PARP1↓, 1,   p‑γH2AX↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

P21↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↓, 2,   ERK↑, 1,   FOXO↑, 1,   GSK‐3β↓, 5,   HDAC↓, 2,   IGF-1↓, 1,   IGFBP3↑, 1,   mTOR↓, 3,   p‑mTOR↑, 1,   PI3K↓, 4,   PI3K↑, 1,   PTEN↑, 1,   RAS↓, 1,   STAT3↓, 1,   TumCG∅, 1,   VGCC↑, 1,   VGCC⇅, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 8,   APP↓, 1,   Ca+2?, 1,   Ca+2↑, 1,   Ca+2↝, 3,   cal2↓, 1,   CLDN1↑, 1,   CLDN1↝, 1,   MMP2↓, 1,   MMP9↓, 4,   MMPs↓, 1,   PKCδ?, 1,   PKCδ↓, 1,   PKCδ↑, 1,   SMAD3↓, 1,   TG2/TGase↓, 1,   TGF-β↓, 2,   TGF-β↑, 1,   Treg lymp↑, 1,   VCAM-1↓, 2,   ZO-1↑, 1,   ZO-1↝, 1,   α-SMA↝, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 2,   angioG↑, 1,   ATF4↓, 2,   EPR↑, 1,   Hif1a↓, 2,   Hif1a↑, 1,   NO?, 1,   NO↓, 8,   NO↑, 1,   TXA2↓, 1,   VEGF↓, 2,   VEGF↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 1,   BBB↑, 10,   CellMemb↑, 1,   GastroP↑, 2,   GLUT1↑, 1,   GLUT3↑, 2,   GLUT4↑, 1,   IBI↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD14↑, 1,   CD4+↑, 1,   COX1↓, 1,   COX2/PTGS2↓, 10,   COX2/PTGS2↑, 1,   CRP↓, 3,   HCAR2↑, 1,   HMGB1↓, 1,   ICAM-1↓, 1,   IFN-γ↓, 4,   IFN-γ↑, 1,   IL1?, 1,   IL1↓, 1,   IL10?, 1,   IL10↓, 4,   IL10↑, 3,   IL17↓, 4,   IL18↓, 2,   IL1β↓, 11,   IL2↓, 1,   IL23↓, 1,   IL4↓, 2,   IL4↑, 1,   IL6?, 1,   IL6↓, 18,   IL8↓, 1,   Imm↓, 1,   Imm↑, 12,   Imm⇅, 1,   Inflam↓, 86,   Inflam↑, 3,   IκB?, 1,   LPS↓, 1,   pol-M2 MC↑, 1,   MCP1/CCL2↓, 2,   MUC2↓, 1,   MyD88↓, 1,   NF-kB↓, 20,   NF-kB↑, 1,   NK cell↑, 1,   p65↓, 1,   PGE2↓, 5,   TLR2↓, 2,   TLR4↓, 4,   TNF-α↓, 23,   TNF-α↑, 2,   VitD↑, 1,  

Cellular Microenvironment(tgid=17) ⓘ

pH↝, 2,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,   AChE↓, 6,   BChE↓, 1,   BDNF↓, 1,   BDNF↑, 3,   GABA↑, 1,   NGF↑, 1,   tau↓, 4,   p‑tau↓, 3,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 3,   Aβ↓, 12,   BACE/β-secretase↓, 4,   NLRP3↓, 3,   XO↝, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CYP19↓, 1,   GR↑, 2,   testos↑, 1,   TSHR↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv?, 1,   BioAv↓, 32,   BioAv↑, 41,   BioAv⇅, 1,   BioAv↝, 12,   BioEnh↑, 5,   CYP2C9↓, 1,   Dose↓, 1,   Dose↑, 5,   Dose↝, 13,   eff↓, 2,   eff↑, 33,   eff↝, 1,   Half-Life↓, 1,   Half-Life↑, 4,   Half-Life⇅, 1,   Half-Life↝, 7,   Half-Life∅, 2,   P450↓, 1,   selectivity↑, 2,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 6,   ALP↓, 3,   AST↓, 9,   BMD↑, 2,   BP↓, 4,   BP∅, 1,   creat↓, 2,   CRP↓, 3,   GutMicro↑, 11,   GutMicro↝, 1,   IL6?, 1,   IL6↓, 18,   LDH↓, 3,   MUC19↓, 1,   NOS2↓, 1,   Urea↓, 1,   VitD↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 4,   antiAll↑, 1,   AntiArt↑, 4,   AntiCan↑, 10,   AntiDiabetic↑, 19,   AntiP↑, 2,   antiPs↑, 2,   AntiTum↓, 1,   AntiTum↑, 3,   Bone Healing↑, 1,   cardioP↑, 27,   CardioT↓, 2,   chemoP↑, 11,   chemoPv↑, 2,   cognitive↓, 1,   cognitive↑, 10,   hepatoP↑, 24,   memory↑, 13,   motorD↑, 1,   neuroP↓, 1,   neuroP↑, 46,   Obesity↓, 9,   Pain↓, 1,   radioP↑, 5,   RenoP↑, 8,   Risk↓, 1,   toxicity?, 2,   toxicity↓, 51,   toxicity↑, 5,   toxicity↝, 12,   toxicity∅, 23,   Weight↝, 1,   Wound Healing↑, 7,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↓, 1,   AntiFungal↑, 4,   AntiViral↑, 11,   Bacteria↓, 24,   Diar↓, 1,   IRF3↓, 1,   Sepsis↓, 3,  
Total Targets: 380

Scientific Paper Hit Count for: eff, efficacy
40 Silver-NanoParticles
30 immunotherapy
29 Curcumin
28 Chemotherapy
26 Vitamin C (Ascorbic Acid)
26 Magnetic Fields
25 chitosan
25 Sulforaphane (mainly Broccoli)
21 EGCG (Epigallocatechin Gallate)
18 Artemisinin
18 Dichloroacetate
17 Radiotherapy/Radiation
17 Thymoquinone
17 Metformin
17 Chrysin
16 Copper and Cu NanoParticles
16 Resveratrol
16 Quercetin
15 diet FMD Fasting Mimicking Diet
14 Capsaicin
14 Bicarbonate(Sodium)
13 3-bromopyruvate
12 Hyperthermia
12 Phenylbutyrate
12 Magnetic Field Rotating
12 Piperlongumine
11 Berberine
10 Ashwagandha(Withaferin A)
10 Cisplatin
10 Atorvastatin
10 Caffeic acid
10 Propolis -bee glue
10 Selenium NanoParticles
10 Citric Acid
9 Gold NanoParticles
9 Fenbendazole
9 Melatonin
9 Apigenin (mainly Parsley)
9 Dandelion Root
9 Fisetin
9 Gambogic Acid
9 Honokiol
9 VitK3,menadione
9 Lycopene
8 Auranofin
8 Photodynamic Therapy
8 SonoDynamic Therapy UltraSound
8 Luteolin
8 Ellagic acid
8 chaetocin
8 Silymarin (Milk Thistle) silibinin
8 salinomycin
8 Exercise
8 doxorubicin
8 Rosmarinic acid
8 Shikonin
8 Selenite (Sodium)
7 Gemcitabine (Gemzar)
7 Carvacrol
7 Selenium
7 Vitamin K2
7 Electrical Pulses
7 Disulfiram
7 Formononetin
6 5-fluorouracil
6 Docetaxel
6 Dipyridamole
6 Baicalein
6 Bifidobacterium
6 Chlorophyllin
6 diet Methionine-Restricted Diet
6 Hydrogen Gas
6 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
6 Ivermectin
6 Kaempferol
5 Astragalus
5 chemodynamic therapy
5 Akkermansia
5 Aspirin
5 Ascorbyl Palmitate
5 beta-glucans
5 Betulinic acid
5 borneol
5 Bortezomib
5 Chlorogenic acid
5 Vitamin D3
5 Gossypol/AT-101
5 Spermidine
5 Inositol
5 Juglone
5 Terpinen-4-ol / Tea Tree Oil
5 Phenethyl isothiocyanate
5 Parthenolide
4 1,8-Cineole
4 cetuximab
4 Coenzyme Q10
4 EMF
4 Astaxanthin
4 Bevacizumab (brand Avastin)
4 Boron
4 Carnosic acid
4 Thymol-Thymus vulgaris
4 Celastrol
4 Folic Acid, Vit B9
4 CUSP9
4 Diclofenac
4 erastin
4 diet Plant based
4 Echinacea
4 Emodin
4 ferumoxytol
4 Ginkgolide B
4 HydroxyCitric Acid
4 Magnolol
4 Isoliquiritigenin
4 Urolithin
3 Cynara scolymus/Globe Artichoke/Artichoke Extract
3 Alpha-Lipoic-Acid
3 Andrographis
3 Arsenic trioxide
3 Berbamine
3 Biochanin A
3 bempedoic acid
3 temozolomide
3 Butyrate
3 Piperine
3 capecitabine
3 hydroxychloroquine
3 Cat’s Claw
3 Docosahexaenoic Acid
3 Oxygen, Hyperbaric
3 Vitamin A, Retinoic Acid
3 eicosapentaenoic acid
3 Eugenol
3 Fucoidan
3 Gallic acid
3 Germanium Organic/Ge-132 / propagermanium (organogermanium)
3 Genistein (soy isoflavone)
3 Ginger/6-Shogaol/Gingerol
3 Hibiscus sabdariffa
3 iodine
3 Inulin Prebiotic
3 itraconazole
3 Licorice
3 Propyl gallate
3 Pterostilbene
3 Whole Body Vibration
2 2-DeoxyGlucose
2 Trichostatin A
2 Glucose
2 Zinc
2 almonertinib
2 Trastuzumab
2 D-limonene
2 Beta-Caryophyllene
2 Bufalin/Huachansu
2 probiotics
2 Boswellia (frankincense)
2 α-Bisabolol / Chamomile oil
2 Bullatacin
2 Sorafenib (brand name Nexavar)
2 carboplatin
2 Centella asiatica / Gotu kola → asiaticoside
2 Hydroxycinnamic-acid
2 Crocetin
2 Cyclopamine
2 Cysteamine
2 Dichloroacetophenone(2,2-)
2 Dasatinib/Phyrago
2 Ferulic acid
2 Vitamin E
2 Geldanamycin
2 Garcinol
2 Ginkgetin
2 Paclitaxel/Taxol
2 isoorientin
2 Lapatinib
2 Lapachol
2 low dose naltrexone
2 Lecithin
2 MCToil
2 magnetic nanoparticles
2 Naringin
2 Niclosamide (Niclocide)
2 Nimbolide
2 Sulfasalazine
1 Anthocyanins
1 Anzaroot, Astragalus fasciculifolius Bioss
1 wortmannin
1 Ajoene (compound of Garlic)
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Amodiaquine
1 Anethole/trans-Anethole
1 Fennel Oil/Foeniculum vulgare
1 Anti-oxidants
1 Allicin (mainly Garlic)
1 5-Aminolevulinic acid
1 Aloe anthraquinones
1 Bromelain
1 brusatol
1 Caffeic Acid Phenethyl Ester (CAPE)
1 urea
1 Cannabidiol
1 Celecoxib
1 Beta‐Lapachone
1 Chocolate
1 Choline
1 Rutin
1 Cinnamon
1 Camptothecin
1 irinotecan
1 Polyphenols
1 Black phosphorus
1 Cucurbitacin
1 gefitinib, erlotinib
1 Deguelin
1 Date Fruit Extract
1 diet Fermented Foods
1 diet Ketogenic
1 diet Short Term Fasting
1 Mistletoe/Viscum album Extracts
1 Cichoric acid / Chicoric acid
1 Ginkgo biloba-EGb 761
1 PXD, phenoxodiol
1 Eurycomanone
1 Vitamin B12
1 Radicicol/monorden
1 olaparib/LYNPARZA
1 Galloflavin
1 verapamil
1 Geraniol
1 Glabrescione B
1 Calorie Restriction Mimetics
1 tamoxifen
1 Helleborus niger extracts – Christmas Rose
1 Baicalin
1 HydroxyTyrosol
1 Indole-3-carbinol
1 isoquercitrin
1 Recombinant Methioninase
1 tumor necrosis factor-related apoptosis-inducing ligand
1 Lactobacillus
1 Laetrile B17 Amygdalin
1 lambertianic acid
1 Licochalcone A
1 Lemongrass Extract/Citral
1 Linalool
1 Lutein
1 Methylene blue
1 metronomic chemo
1 Caffeine
1 methotrexate
1 Magnesium
1 Methylglyoxal
1 Mushroom Reishi
1 Myricetin
1 Oleocanthal
1 Orlistat
1 Marjoram (Origanum majorana)
1 sericin
1 Psoralidin
1 enzalutamide
1 Rauwolfia serpentina/Indian Snakeroot
1 polyethylene glycol
1 acetaminophen
1 acetazolamide
1 Iron
1 Squalene
1 Glutathione
1 statins
1 Sutherlandioside D
1 Taurine
1 Aflavin-3,3′-digallate
1 tetrathiomolybdate
1 Triphala
1 triptolide
1 Turmerones
1 Vitamin B1/Thiamine
1 Vitexin
1 Wogonin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:961  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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