other Cancer Research Results

other, other: Click to Expand ⟱
Source:
Type:
custom
Scientific Papers found: Click to Expand⟱
2327- 2DG,    2-Deoxy-d-Glucose and Its Analogs: From Diagnostic to Therapeutic Agents
- Review, Var, NA
Glycolysis↓, HK2↓, mt-ROS↑, AMPK↑, PPP↓, NADPH↓, GSH↓, Bax:Bcl2↑, Apoptosis↑, RadioS↑, eff↓, Half-Life↓, other↝, eff↓,
5270- 5-ALA,  PDT,    5-Aminolevulinic Acid as a Theranostic Agent for Tumor Fluorescence Imaging and Photodynamic Therapy
- Review, Var, NA
other↝, ROS↑, other↝, mtDam↑, Ca+2↑, ER Stress↑, Apoptosis↑, TumAuto↑, other↝, Dose↝, Imm↑,
7981- AAS/EEAA,    Chemopreventive Potential of Oils Extracted from Seeds of Three Annona Species
- Review, Var, NA
other↝, chemoPv↑,
5470- AF,    Exploring a Therapeutic Gold Mine: The Antifungal Potential of the Gold-Based Antirheumatic Drug Auranofin
- Review, Var, NA
TrxR↓, other↝, IL6↑, IL8↑, NK cell⇅, COX2/PTGS2↓, NOS2↓, NRF2↑, Prx↑, Half-Life↑, Dose↝, ROS↑, NF-kB↓,
5429- AG,    Astragalus polysaccharides improve adjuvant chemotherapy-induced fatigue for patients with early breast cancer
- Human, BC, NA
chemoP↑, other↝,
4400- AgNPs,  Rad,    Differential cytotoxic and radiosensitizing effects of silver nanoparticles on triple-negative breast cancer and non-triple-negative breast cells
- in-vitro, BC, MCF7 - in-vitro, Nor, MCF10 - in-vitro, BC, MDA-MB-231 - in-vitro, BC, BT549 - in-vivo, BC, MDA-MB-231
ROS↑, DNAdam↑, selectivity↑, TumCG↓, RadioS↑, Dose↝, selectivity↑, other↝, eff↓, eff↑, γH2AX↑, Dose↓, eff↑,
4421- AgNPs,    Effect of Biologically Synthesized Silver Nanoparticles on Human Cancer Cells
- in-vitro, Cerv, NA
selectivity↑, eff↝, other↝,
4419- AgNPs,    Tackling the various classes of nano-therapeutics employed in topical therapy of psoriasis
- NA, PSA, NA
IL1α↓, other↝,
4561- AgNPs,  VitC,    Cellular Effects Nanosilver on Cancer and Non-cancer Cells: Potential Environmental and Human Health Impacts
- in-vitro, CRC, HCT116 - in-vitro, Nor, HEK293
NRF2↑, TumCCA↑, ROS↑, selectivity↑, *AntiViral↑, *toxicity↝, ETC↓, MMP↓, DNAdam↑, Apoptosis↑, lipid-P↑, other↝, UPR↑, *GRP78/BiP↑, *p‑PERK↑, *cl‑eIF2α↑, *CHOP/DDIT3↑, *JNK↑, Hif1a↓, AntiCan↑, *toxicity↓, eff↑,
4549- AgNPs,    Silver nanoparticles: Synthesis, medical applications and biosafety
- Review, Var, NA - Review, Diabetic, NA
ROS↑, eff↑, other↝, DNAdam↑, EPR↑, eff↑, eff↑, TumMeta↓, angioG↓, *Bacteria↓, *eff↑, *AntiViral↑, *AntiFungal↑, eff↑, eff↑, TumCP↓, tumCV↓, P53↝, HIF-1↓, TumCCA↑, lipid-P↑, ATP↓, Cyt‑c↑, MMPs↓, PI3K↓, Akt↓, *Wound Healing↑, *Inflam↓, *Bone Healing↑, *glucose↓, *AntiDiabetic↑, *BBB↑,
305- AgNPs,    Activity and pharmacology of homemade silver nanoparticles in refractory metastatic head and neck squamous cell cancer
- Case Report, HNSCC, NA
OS↑, Dose↓, BioAv↝, toxicity↓, Remission↑, other↝, other↝, other↝, Dose↝, BioAv↝,
391- AgNPs,    Silver nanoparticles inhibit VEGF-and IL-1β-induced vascular permeability via Src dependent pathway in porcine retinal endothelial cells
- in-vitro, Nor, NA
*VEGF↓, *IL1↓, toxicity↝, other↝,
5343- Ajoene,    The garlic compound ajoene covalently binds vimentin, disrupts the vimentin network and exerts anti-metastatic activity in cancer cells
- in-vitro, Cerv, HeLa - in-vitro, BC, MDA-MB-231
Vim↑, TumCI↓, TumCMig↓, TumMeta↓, Vim↓, other↝,
550- AL,    A Review on Anticancer Activities of Garlic (Allium sativum L.)
- Review, NA, NA
ChemoSideEff↓, other↝,
2667- AL,    Allicin in Digestive System Cancer: From Biological Effects to Clinical Treatment
- Review, GC, NA
AntiCan↑, ChemoSen↑, angioG↓, chemoP↑, *GutMicro↑, *antiOx↑, other↝, GSH↓, Thiols↓, *ROS↓, *hepatoP↑, *Inflam↓, *NF-kB↓,
3443- ALA,    Molecular and Therapeutic Insights of Alpha-Lipoic Acid as a Potential Molecule for Disease Prevention
- Review, Var, NA - Review, AD, NA
*antiOx↑, *ROS↓, *IronCh↑, *cognitive↑, *cardioP↓, AntiCan↑, *neuroP↑, *Inflam↓, *BioAv↓, *AntiAge↑, *Half-Life↓, *BioAv↝, other↝, EGFR↓, Akt↓, ROS↓, TumCCA↑, p27/CDKN1B↑, PDH↑, Glycolysis↓, ROS↑, *eff↑, *memory↑, *motorD↑, *GutMicro↑,
4758- antiOx,  Chemo,    Therapeutic controversies over use of antioxidant supplements during cancer treatment: a scoping review
- Review, Var, NA
ChemoSen↓, other↝, other↝,
4746- antiOx,  Chemo,  VitA,RetA,  VitC,  Se  Using Supplements During Chemo: Yes or No?
- Review, Var, NA
eff↓, ChemoSen↓, RadioS↓, other↝,
2320- ART/DHA,    Dihydroartemisinin Inhibits the Proliferation of Leukemia Cells K562 by Suppressing PKM2 and GLUT1 Mediated Aerobic Glycolysis
- in-vitro, AML, K562 - in-vitro, Liver, HepG2
Glycolysis↓, GlucoseCon↓, lactateProd↓, GLUT1↓, PKM2↓, ECAR↓, LDHA↓, cMyc↓, other↝,
2580- ART/DHA,  VitC,    Effects of Antioxidants and Pro-oxidants on Cytotoxicity of Dihydroartemisinin to Molt-4 Human Leukemia Cells
- in-vitro, AML, NA
eff↓, other↝, ROS↑, eff↓, eff↓,
5403- ASA,    Low-Dose Aspirin for PI3K-Altered Localized Colorectal Cancer
- Trial, CRC, NA
Risk↓, other↝,
5399- ASA,    Effect of Aspirin on Cancer Incidence and Mortality in Older Adults
- Trial, Nor, NA
Risk↝, Risk↑, Risk∅, Risk↑, other↝,
5404- ASA,    Low-Dose Aspirin and Prevention of Colorectal Cancer: Evidence From a Nationwide Registry-Based Cohort in Norway
- Study, CRC, NA
Risk↓, other↝, Dose↝, Risk↓, other↓, other↝, KRAS↓, other↓, other↓,
5453- ATV,    Epidemiologic Analysis Along the Mevalonate Pathway Reveals Improved Cancer Survival in Patients Who Receive Statins Alone and in Combination With Bisphosphonates
- Trial, Var, NA
OS↑, eff↑, other↝,
2712- BBR,    Suppression of colon cancer growth by berberine mediated by the intestinal microbiota and the suppression of DNA methyltransferases (DNMTs)
- in-vitro, Colon, HT29 - in-vivo, NA, NA
TumCG↓, GutMicro↑, other↝, IL10↓, cMyc↓, DNMT1↓, DNMTs↓,
5640- BCA,    Improved effectiveness of biochanin A as a P-gp inhibitor in solid dispersion
- in-vitro, Nor, NA
*P-gp/ABCB1↓, BioAv↑, other↝, other↑,
5512- bemA,    Recent advance of ATP citrate lyase inhibitors for the treatment of cancer and related diseases
- Review, Var, NA
ACLY↓, other↝, CSCs↓,
5513- bemA,    ACLY inhibition promotes tumour immunity and suppresses liver cancer
- in-vitro, Liver, NA
ACLY↓, AMPK↑, eff↑, other↝, eff↝,
5723- BF,    Unique Oxidative Metabolism of Bufalin Generates Two Reactive Metabolites That Strongly Inactivate Human Cytochrome P450 3A
- Study, NA, NA
other↝,
5730- BF,    Bufalin Is a Potent Small-Molecule Inhibitor of the Steroid Receptor Coactivators SRC-3 and SRC-1
- in-vitro, BC, MCF7 - in-vitro, Lung, A549
other↝, TumCP↓,
5686- BJ,  BRU,    A review of Brucea javanica: metabolites, pharmacology and clinical application
- Review, Var, NA
AntiTum↑, other↝, ChemoSen↑, QoL↑, chemoP↑, *Inflam↓, NF-kB↓, TumCP↓, TumCI↓, TumMeta↓, Hif1a↓, NRF2↓, STAT3↓, COX2/PTGS2↓, Casp3↑, Casp9↑, ROS↑, EGFR↓, NRF2↑,
5479- BM,    Importance of high-quality evidence regarding the use of Bacopa monnieri in dementia
- Review, AD, NA
other↝,
5656- BNL,    Role of borneol as enhancer in drug formulation: A review
- Review, Nor, NA - Review, Stroke, NA - Review, AD, NA
*eff↑, BBB↑, ChemoSen↑, *Inflam↓, *NO↓, *TNF-α↓, *IL6↓, *Bacteria↓, *eff↑, *Aβ↓, *SOD↑, *neuroP↑, *EPR↑, toxicity↓, P-gp/ABCB1↓, eff↑, other↝,
5654- BNL,    Pharmacokinetics of natural borneol after oral administration in mice brain and its effect on excitation ratio
- in-vivo, Nor, NA
*BioAv↑, *Half-Life↝, other↝,
5660- BNL,    Recent Progress on the Synergistic Antitumor Effect of a Borneol-Modified Nanocarrier Drug Delivery System
- Review, Var, NA
TumMeta↓, BBB↑, EPR↑, toxicity↓, BioAv↑, ChemoSen↑, eff↑, other↑, P-gp/ABCB1↓, MDR1↓, ROS↑, TumCCA↑, other↝, BioAv↓, DNAdam↑, BioEnh↑,
4620- Bor,  BTZ,    Boron Compounds in the Breast Cancer Cells Chemoprevention and Chemotherapy
- Review, Var, NA - Review, Arthritis, NA - Review, Pca, NA
Risk↓, *memory↑, *Dose↑, Risk↓, other↝, *testos↑, other↝, Risk↓, TumCP↓, Apoptosis↑, eff↑,
4619- Bor,    Using Boron Supplementation in Cancer Prevention and Treatment: A Review Article
- Review, Var, NA
Dose↝, Risk↓, *antiOx↓, *Inflam↓, ChemoSen↑, AntiCan↑, *PCNA↓, *ROS↓, other↝,
5740- Buty,    A Review of Nutritional Regulation of Intestinal Butyrate Synthesis: Interactions Between Dietary Polysaccharides and Proteins
- Review, RCC, NA
*eff↓, Dose↝, eff↑, HDAC↓, ac‑H3↓, ac‑H4↓, *HCAR2↑, *Inflam↓, *ROS↓, *NRF2↑, *GSH↑, *CLDN1↑, *ZO-1↑, IL1β↓, IL6↓, COX2/PTGS2↓, eff↝, eff↑, other↝,
5731- Buty,    The Warburg Effect Dictates the Mechanism of Butyrate Mediated Histone Acetylation and Cell Proliferation
- in-vitro, CRC, HCT116 - in-vitro, CRC, HT29
HDAC↓, Warburg↓, TumCP⇅, HATs↑, BioAv↓, other↝, Risk↓,
5867- CA,    Inhibitory effects of rosemary extracts, carnosic acid and rosmarinic acid on the growth of various human cancer cell lines
- in-vitro, Pca, DU145 - in-vitro, Liver, Hep3B - in-vitro, AML, K562 - in-vitro, Pca, PC3 - in-vitro, BC, MDA-MB-231
TumCP↓, eff↑, other↝,
5875- CA,    Carnosic acid prevents dextran sulfate sodium-induced acute colitis associated with the regulation of the Keap1/Nrf2 pathway
- in-vivo, IBD, NA
*antiOx↑, *Weight↑, *p65↓, *cJun↓, *NLRP3↓, *Casp1↓, *NRF2↑, *GSH↑, *SOD↑, *MDA↓, *iNOS↓, other↝,
2016- CAP,    Capsaicin binds the N-terminus of Hsp90, induces lysosomal degradation of Hsp70, and enhances the anti-tumor effects of 17-AAG (Tanespimycin)
HSP90↓, ATPase↓, eff↑, HSP70/HSPA5↓, other↝, NF-kB↓, EGFR↓, CDK4↓, Src↓, VEGF↓, PI3K↓, Akt↓,
5820- CBD,    Cannabidiol effects in stem cells: A systematic review
- Review, Var, NA
*other↑, CSCs↓, SOX2↓, other↝,
5942- Cela,    Celastrol elicits antitumor effects by inhibiting the STAT3 pathway through ROS accumulation in non-small cell lung cancer
- vitro+vivo, NSCLC, H460 - in-vitro, NSCLC, PC9
TumCG↓, TumCP↓, TumMeta↓, ROS↑, ER Stress↑, p‑STAT3↓, Apoptosis↑, eff↓, TumCG↓, IL6↓, other↝,
7165- CHA,    The anticancer agent chaetocin is a competitive substrate and inhibitor of thioredoxin reductase
- in-vitro, Cerv, HeLa
ROS↑, TumCD↑, TrxR1↓, other↝, GSR↓, Trx↓, eff↓,
7159- CHA,    ROS-mediated inactivation of the PI3K/AKT pathway is involved in the antigastric cancer effects of thioredoxin reductase-1 inhibitor chaetocin
- vitro+vivo, GC, HGC27 - in-vitro, GC, AGS - in-vitro, GC, BGC-823 - in-vitro, GC, SGC-7901 - in-vitro, Nor, HEK293
TumCP↓, TumCCA↑, Casp↑, Apoptosis↑, TrxR1↓, ROS↑, eff↓, eff↑, PI3K↓, Akt↓, TumCG↓, cl‑PARP↑, cl‑Casp3↑, cl‑Casp9↑, cl‑Casp8↑, Bcl-2↓, Bcl-xL↓, Mcl-1↓, XIAP↓, survivin↓, TumVol↓, TumW↓, Weight∅, toxicity↓, Ki-67↓, other↝,
2175- Chemo,  VitB12,  FA,    Systemic Chemotherapy Interferes in Homocysteine Metabolism in Breast Cancer Patients
- Study, BC, NA
other↓, other↝, Hcy/homoC↓, eff↝, other↝,
6000- Chit,    Chitosan in Modern Pharmacotherapy: From Drug Encapsulation to Targeted Delivery Systems
- Review, Var, NA
DDS↑, toxicity↓, TJ↓, BioAv↑, *Bacteria↓, *Inflam↓, *antiOx↓, Wound Healing↑, other↝, eff↑, eff↑,
5987- Chit,    Chitin, Chitosan, and Glycated Chitosan Regulate Immune Responses: The Novel Adjuvants for Cancer Vaccine
- Review, Var, NA
other↝, other↝, *Weight↝, *toxicity↓, *Bacteria↓, *BioAv↑, DDS↑, *Wound Healing↑, *other↝, *Imm↑, eff↑, *BioAv↝, *BioAv↑, eff↑, NK cell↑, IL2↑, IFN-γ↑, IL10↑,
5994- Chit,    Anticancer Activity of Chitosan, Chitosan Derivatives, and Their Mechanism of Action
- Review, Var, NA
angioG↓, *Imm↑, *antiOx↑, selectivity↑, other↝, toxicity↓, BioAv↑, eff↝, Half-Life↑, MPT↑, MMP9↓, lipid-P↑, EPR↑, NK cell↑, Casp3↑, Casp8↑, TumCCA↑, ROS↑, DDS↑, VEGF↓, TIMP1↑, ChemoSen↑, eff↑,

Showing Research Papers: 1 to 50 of 172
Page 1 of 4 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 172

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

anemia↓, 1,   CD155↓, 1,   CIT↓, 1,   CUL1↝, 1,   CUL5↝, 1,   CX43/GJA1↓, 1,   DCR↑, 1,   HLA-I/II↑, 1,   miR-375↑, 1,   Nausea↓, 1,   NPL4↓, 1,   PC↑, 1,   PFS↑, 2,   PSEN1/PS1↓, 1,   SCP2↓, 1,   Vomit↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   ARE↓, 1,   Catalase↓, 1,   CYP1A1↑, 1,   CYP2E1↑, 1,   Fenton↑, 2,   Ferroptosis↓, 1,   Ferroptosis↑, 3,   GPx4↓, 3,   GSH↓, 5,   GSR↓, 1,   GSTs↓, 1,   GSTZ1↓, 1,   H2O2↑, 2,   HO-1↓, 1,   HO-1↑, 1,   Iron↑, 1,   Iron↝, 1,   lipid-P↑, 7,   lipid-P↝, 1,   i-MDA↑, 1,   MGO↑, 1,   NQO1↓, 1,   NRF2↓, 3,   NRF2↑, 5,   NRF2↝, 1,   OXPHOS↓, 1,   OXPHOS↑, 2,   Prx↑, 1,   RNS↑, 1,   ROS↓, 3,   ROS↑, 38,   ROS⇅, 1,   mt-ROS↓, 1,   mt-ROS↑, 3,   SOD↓, 1,   Thiols↓, 2,   Trx↓, 1,   TrxR↓, 1,   TrxR1↓, 2,   xCT/SLC7A11↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ATP↓, 5,   CDC25↓, 1,   CDC25↝, 1,   COX17↝, 1,   ETC↓, 3,   Insulin↓, 1,   MEK↓, 1,   MMP↓, 9,   MPT↑, 1,   mtDam↑, 5,   OCR↓, 3,   OCR↑, 1,   c-Raf↓, 1,   XIAP↓, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACLY↓, 2,   AKT1↓, 2,   ALAT↓, 1,   AMPK↑, 3,   cMyc↓, 2,   cMyc↑, 1,   CYP3A4↓, 1,   CYP3A4⇅, 1,   ECAR↓, 1,   glucose↝, 1,   GlucoseCon↓, 1,   GlucoseCon↑, 1,   Glycolysis↓, 9,   HK2↓, 2,   HMG-CoA↓, 1,   lactateProd↓, 3,   LDHA↓, 3,   lipoGen↓, 2,   NAD↓, 1,   NADPH↓, 2,   NADPH↑, 1,   PDH↑, 1,   PDK1 / PDPK1↓, 1,   PKM2↓, 3,   PPP↓, 1,   PPP↑, 1,   p‑S6K↓, 1,   SIRT1↑, 1,   SREBP1/SREBF1↓, 1,   Warburg↓, 3,  

Cell Death(tgid=5) ⓘ

Akt↓, 12,   Akt↑, 1,   p‑Akt↓, 1,   Apoptosis↑, 31,   BAX↑, 6,   Bax:Bcl2↑, 3,   Bcl-2↓, 9,   Bcl-xL↓, 1,   BID↑, 1,   Casp↑, 4,   Casp12↑, 1,   Casp3↑, 8,   cl‑Casp3↑, 4,   Casp7↑, 1,   Casp8↑, 2,   cl‑Casp8↑, 1,   Casp9↑, 6,   cl‑Casp9↑, 3,   Cyt‑c↑, 6,   Cyt‑c↝, 2,   DR4↑, 2,   Fas↑, 1,   FasL↑, 1,   Ferroptosis↓, 1,   Ferroptosis↑, 3,   hTERT/TERT↓, 1,   JNK↑, 1,   MAPK↑, 2,   Mcl-1↓, 2,   MDM2↓, 2,   MOMP↑, 1,   necrosis↑, 1,   NOXA↑, 1,   p27/CDKN1B↓, 1,   p27/CDKN1B↑, 1,   p38↑, 1,   p‑p38↑, 1,   survivin↓, 4,   Telomerase↓, 1,   TumCD↓, 1,   TumCD↑, 7,  

Kinase & Signal Transduction(tgid=6) ⓘ

HER2/EBBR2↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

ac‑H3↓, 1,   ac‑H4↓, 1,   HATs↑, 1,   other↓, 6,   other↑, 9,   other↝, 203,   other∅, 2,   p‑pRB↓, 1,   tumCV↓, 6,   tumCV↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1,   eIF2α↑, 1,   ER Stress↑, 5,   GRP78/BiP↑, 1,   HSP70/HSPA5↓, 1,   HSP90↓, 3,   IRE1↓, 1,   UPR↑, 2,   mt-UPR↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 2,   LC3B↑, 1,   TumAuto↑, 9,   TumAuto↝, 1,  

DNA Damage & Repair(tgid=10) ⓘ

CHK1↝, 1,   DNAdam↑, 9,   DNMT1↓, 1,   DNMTs↓, 1,   P53↓, 2,   P53↑, 6,   P53↝, 2,   PARP↑, 3,   cl‑PARP↑, 3,   PCNA↓, 1,   RAD51↓, 1,   γH2AX↑, 3,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK1↓, 1,   CDK1↝, 1,   CDK4↓, 1,   CycB/CCNB1↓, 1,   CycB/CCNB1↝, 1,   cycD1/CCND1↓, 1,   P21↓, 1,   P21↑, 4,   TumCCA↑, 21,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CD44↓, 1,   CSCs↓, 7,   EMT↓, 5,   ERK↓, 5,   p‑ERK↝, 1,   FOXO1↑, 1,   GSK‐3β↓, 1,   HDAC↓, 3,   HH↓, 4,   HH∅, 1,   mTOR↓, 2,   mTOR↑, 1,   NOTCH1↓, 1,   PI3K↓, 9,   SOX2↓, 1,   Src↓, 1,   STAT3↓, 3,   p‑STAT3↓, 2,   TOP1↓, 1,   TRPM7↑, 1,   TumCG↓, 23,   TumCG↑, 2,   VGCC↑, 1,   Wnt↓, 3,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   ATOX1↝, 1,   ATPase↓, 2,   Ca+2↑, 4,   Ca+2↝, 1,   CD31/PECAM-1↓, 1,   Cofilin↓, 1,   E-cadherin↑, 3,   FAK↓, 2,   fascin↓, 1,   ITGB1↓, 2,   ITGB6↓, 1,   Ki-67↓, 3,   KRAS↓, 1,   MMP2↓, 4,   MMP9↓, 3,   MMPs↓, 4,   N-cadherin↓, 2,   ROCK1↓, 1,   Smad1↑, 1,   Snail↓, 1,   TGF-β↓, 1,   TIMP1↑, 1,   TJ↓, 1,   TumCA↓, 1,   TumCI↓, 8,   TumCI↑, 1,   TumCMig↓, 8,   TumCMig↑, 1,   TumCP↓, 27,   TumCP↑, 2,   TumCP⇅, 1,   TumMeta↓, 12,   Vim↓, 3,   Vim↑, 1,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 12,   EGFR↓, 7,   EPR↑, 5,   HIF-1↓, 2,   Hif1a↓, 5,   Hypoxia↓, 1,   PDI↑, 2,   VEGF↓, 5,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 2,   CellMemb↑, 3,   CTR1↝, 1,   GLUT1↓, 1,   P-gp/ABCB1↓, 2,   sonoP↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD25+↓, 1,   CD4+↓, 1,   COX2/PTGS2↓, 8,   COX2/PTGS2↑, 1,   FoxP3+↓, 1,   GM-CSF↓, 1,   HMGB1↓, 1,   ICAM-1↓, 1,   IFN-γ↑, 1,   IL10↓, 1,   IL10↑, 1,   IL1α↓, 1,   IL1β↓, 2,   IL2↑, 1,   IL6↓, 3,   IL6↑, 1,   IL8↓, 1,   IL8↑, 1,   Imm↑, 7,   Inflam↓, 3,   JAK2↓, 1,   NF-kB↓, 11,   NK cell↑, 3,   NK cell⇅, 1,   PGE2↓, 2,   PSA↓, 2,   TLR4↓, 1,   TNF-α↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

pH∅, 1,   e-pH↓, 1,   e-pH↑, 1,   i-pH↓, 1,   Temp∅, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

GABA↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↝, 1,   testos∅, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 5,   BioAv↑, 13,   BioAv↝, 6,   BioEnh↑, 1,   ChemoSen↓, 3,   ChemoSen↑, 21,   ChemoSen∅, 1,   CYP1A2↑, 1,   CYP2A3/CYP2A6↓, 1,   DDS↑, 3,   Dose↓, 5,   Dose↑, 3,   Dose↝, 40,   eff↓, 18,   eff↑, 55,   eff↝, 17,   eff∅, 1,   Half-Life↓, 2,   Half-Life↑, 2,   Half-Life↝, 1,   MDR1↓, 1,   P450↓, 2,   RadioS↓, 1,   RadioS↑, 5,   RadioS↝, 1,   selectivity?, 1,   selectivity↑, 21,   TET2↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AR↝, 1,   AST↓, 1,   CA125∅, 1,   CTC↓, 1,   EGFR↓, 7,   Ferritin↑, 1,   GutMicro↑, 2,   Hcy/homoC↓, 1,   HER2/EBBR2↓, 2,   hTERT/TERT↓, 1,   IL6↓, 3,   IL6↑, 1,   Ki-67↓, 3,   KRAS↓, 1,   NOS2↓, 1,   PSA↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiCan↓, 2,   AntiCan↑, 12,   AntiDiabetic↑, 1,   antiNeop↑, 1,   AntiTum↓, 1,   AntiTum↑, 6,   chemoP↑, 8,   chemoPv↑, 2,   ChemoSideEff↓, 1,   fatigue↓, 1,   hepatoP↑, 2,   MusCon↓, 1,   Obesity↑, 1,   OS↑, 11,   Pin1↓, 1,   QoL↑, 5,   Remission↑, 2,   Risk↓, 12,   Risk↑, 4,   Risk↝, 1,   Risk∅, 1,   toxicity↓, 11,   toxicity↑, 2,   toxicity⇅, 1,   toxicity↝, 9,   TumVol↓, 8,   TumVol↑, 1,   TumW↓, 3,   Weight↑, 1,   Weight∅, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

Inf↑, 1,   Sepsis↑, 1,  
Total Targets: 379

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 3,   antiOx↑, 10,   GPx↑, 1,   GPx1↑, 1,   GSH↑, 2,   lipid-P↓, 3,   MDA↓, 1,   NRF2↑, 2,   ROS↓, 8,   ROS↑, 1,   selenoP↑, 2,   SOD↑, 3,   SOD1↑, 1,   SOD2↑, 1,   VitC↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ETC↝, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

glucose↓, 1,  

Cell Death(tgid=5) ⓘ

Casp1↓, 1,   iNOS↓, 1,   JNK↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

HCAR2↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

BowelM↑, 1,   cJun↓, 1,   other↑, 1,   other↝, 5,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1,   cl‑eIF2α↑, 1,   GRP78/BiP↑, 1,   p‑PERK↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

PCNA↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   CLDN1↑, 1,   ZO-1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   EPR↑, 1,   NO↓, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   P-gp/ABCB1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

HCAR2↑, 1,   IL1↓, 1,   IL6↓, 2,   Imm↑, 3,   Inflam↓, 11,   NF-kB↓, 1,   p65↓, 1,   TNF-α↓, 2,  

Synaptic & Neurotransmission(tgid=18) ⓘ

tau↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 2,   NLRP3↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

testos↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 3,   BioAv↑, 8,   BioAv↝, 2,   Dose↑, 1,   Dose↝, 3,   eff↓, 1,   eff↑, 6,   Half-Life↓, 1,   Half-Life↝, 2,   TET2↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

GutMicro↑, 3,   IL6↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   AntiDiabetic↑, 1,   Bone Healing↑, 1,   cardioP↓, 1,   cardioP↑, 1,   chemoP↑, 1,   cognitive↑, 2,   hepatoP↑, 1,   memory↑, 3,   motorD↑, 1,   neuroP↑, 4,   Pain↓, 1,   radioP↑, 1,   toxicity↓, 8,   toxicity↑, 1,   toxicity↝, 5,   Weight↑, 1,   Weight↝, 1,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 2,   AntiViral↑, 2,   Bacteria↓, 6,  
Total Targets: 86

Scientific Paper Hit Count for: other, other
8 Vitamin C (Ascorbic Acid)
7 Silver-NanoParticles
7 itraconazole
6 Chemotherapy
6 Selenium
6 Curcumin
5 chitosan
5 Hydrogen Gas
5 Selenite (Sodium)
4 Choline
4 Electrical Pulses
3 Radiotherapy/Radiation
3 Anti-oxidants
3 Aspirin
3 borneol
3 Cynara scolymus/Globe Artichoke/Artichoke Extract
3 Polyphenols
3 EGCG (Epigallocatechin Gallate)
3 Fisetin
3 Magnetic Fields
2 Allicin (mainly Garlic)
2 Artemisinin
2 bempedoic acid
2 Bufalin/Huachansu
2 Boron
2 Butyrate
2 Carnosic acid
2 chaetocin
2 Coenzyme Q10
2 Diclofenac
2 diet Methionine-Restricted Diet
2 Echinacea
2 5-fluorouracil
2 Emodin
2 Geldanamycin
2 Formononetin
2 Ginkgolic acids
2 Germanium Organic/Ge-132 / propagermanium (organogermanium)
2 IP6 (Inositol 1,2,3,4,5,6-hexakisphosphate)
2 Lactoferrin/Talactoferrin
2 Magnetic Field Rotating
2 Phenylbutyrate
2 Phenethyl isothiocyanate
2 Selenium NanoParticles
1 2-DeoxyGlucose
1 5-Aminolevulinic acid
1 Photodynamic Therapy
1 Annona atemoya Seed Extract
1 Auranofin
1 Astragalus
1 Ajoene (compound of Garlic)
1 Alpha-Lipoic-Acid
1 Vitamin A, Retinoic Acid
1 Atorvastatin
1 Berberine
1 Biochanin A
1 Brucea javanica
1 brusatol
1 Bacopa monnieri
1 Bortezomib
1 Capsaicin
1 Cannabidiol
1 Celastrol
1 Vitamin B12
1 Folic Acid, Vit B9
1 Citric Acid
1 Carica papaya leaf extract
1 Camptothecin
1 irinotecan
1 Copper and Cu NanoParticles
1 CUSP9
1 Cynaropicrin
1 Dasatinib/Phyrago
1 Dichloroacetate
1 Deguelin
1 Dandelion Root
1 Disulfiram
1 Ellagic acid
1 doxorubicin
1 Ginkgo biloba-EGb 761
1 Eugenol
1 Radicicol/monorden
1 Shilajit/Fulvic Acid
1 Genistein (soy isoflavone)
1 Resveratrol
1 Sulforaphane (mainly Broccoli)
1 Geraniol
1 Ginkgolide B
1 Ginger/6-Shogaol/Gingerol
1 Gossypol/AT-101
1 Graviola
1 Hibiscus sabdariffa
1 High-Ozonide Oil
1 Inositol
1 iodine
1 isoflavones
1 Ivermectin
1 Juglone
1 Lactobacillus
1 Laetrile B17 Amygdalin
1 Licochalcone A
1 Luteolin
1 Magnesium
1 Methylglyoxal
1 Nimbolide
1 Peppermint
1 Parthenolide
1 Ramucirumab (CYRAMZA)
1 Radio Frequency
1 EMF
1 salinomycin
1 SonoDynamic Therapy UltraSound
1 Oxygen, Hyperbaric
1 Shikonin
1 Terpinen-4-ol / Tea Tree Oil
1 Urolithin
1 diet Short Term Fasting
1 glucose deprivation
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:0  prod#:%  Target#:767  State#:%  Dir#:4
  wNotes=0  sortOrder:rid,rpid

 

Home Page