toxicity Cancer Research Results

toxicity, toxicity: Click to Expand ⟱
Source:
Type:
Toxicity


Scientific Papers found: Click to Expand⟱
1602- Cu,    A simultaneously GSH-depleted bimetallic Cu(ii) complex for enhanced chemodynamic cancer therapy†
- in-vitro, BC, MCF7 - in-vitro, BC, 4T1 - in-vitro, Lung, A549 - in-vitro, Liver, HepG2
eff↑, GSH↓, H2O2↑, ROS↑, *BioAv↑, selectivity↑, TumCCA↑, Apoptosis↑, Fenton↑, *toxicity?,
6288- DL,    From Citrus to Clinic: Limonene’s Journey Through Preclinical Research, Clinical Trials, and Formulation Innovations
- Review, Var, NA - Review, AD, NA
other↑, DDS↑, *antiOx↑, *Inflam↓, *AntiDiabetic↑, *neuroP↑, *Imm↑, *Wound Healing↑, *other↑, *BioAv↑, *ROS↓, *SOD↑, *Catalase↑, *GSH↑, *DNAdam↓, *AntiDiabetic↑, Casp3↑, Casp9↑, BAX↑, Bcl-2↓, *AChE↓, *BChE↓, *Aβ↓, *ROS↓, *toxicity?,
7598- HPT,  Rad,  Chemo,    The role of capacitive hyperthermia as an adjunct treatment in oncology: a systematic review of randomized phase III trials
- Review, Var, NA
OS↑, TR↑, LC↑, *toxicity?,
8793- mCHEMO,    Metronomic Chemotherapy in Breast Cancer as a Strategy to Deliver More Sustainable and Less Toxic Treatments: Time to Debunk the Myth?
- Review, Var, NA
*toxicity?, eff↝, other↝,
3457- MF,    Cellular stress response to extremely low‐frequency electromagnetic fields (ELF‐EMF): An explanation for controversial effects of ELF‐EMF on apoptosis
- Review, Var, NA
Apoptosis↑, H2O2↑, ROS↑, RadioS↑, eff↑, Ca+2↑, MAPK↑, *Catalase↑, *SOD1↑, *GPx1↑, *GPx4↑, *NRF2↑, TumAuto↑, ER Stress↑, HSPs↑, SIRT3↑, ChemoSen↑, UPR↑, other↑, PI3K↓, JNK↑, p38↑, eff↓, *toxicity?,
7382- MFrot,    Inhibition of mitochondrial NADH:ubiquinone oxidoreductase by spinning oscillating magnetic fields causes toxicity in cancer cells
- vitro+vivo, GBM, NA
ROS↑, compI↓, DNAdam↑, TumCCA↑, Casp↓, Apoptosis↑, mt-NADH↓, selectivity?, *toxicity?,

Showing Research Papers: 1 to 6 of 6

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 6

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

Fenton↑, 1,   GSH↓, 1,   H2O2↑, 2,   mt-NADH↓, 1,   ROS↑, 3,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↓, 1,   SIRT3↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 3,   BAX↑, 1,   Bcl-2↓, 1,   Casp↓, 1,   Casp3↑, 1,   Casp9↑, 1,   p38↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

JNK↑, 1,   MAPK↑, 1,   PI3K↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 2,   other↝, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↑, 1,   HSPs↑, 1,   UPR↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 2,  

Migration(tgid=13) ⓘ

Ca+2↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ChemoSen↑, 1,   DDS↑, 1,   eff↓, 1,   eff↑, 2,   eff↝, 1,   RadioS↑, 1,   selectivity?, 1,   selectivity↑, 1,  

Functional Outcomes(tgid=23) ⓘ

LC↑, 1,   OS↑, 1,   TR↑, 1,  
Total Targets: 37

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   Catalase↑, 2,   GPx1↑, 1,   GPx4↑, 1,   GSH↑, 1,   NRF2↑, 1,   ROS↓, 2,   SOD↑, 1,   SOD1↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Imm↑, 1,   Inflam↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,   BChE↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiDiabetic↑, 2,   neuroP↑, 1,   toxicity?, 6,   Wound Healing↑, 1,  
Total Targets: 21

Scientific Paper Hit Count for: toxicity, toxicity
1 Copper and Cu NanoParticles
1 D-limonene
1 Hyperthermia
1 Radiotherapy/Radiation
1 Chemotherapy
1 MCT, metronomic chemo
1 Magnetic Fields
1 Magnetic Field Rotating
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:1025  State#:%  Dir#:0
wNotes=0 sortOrder:rid,rpid

 

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