NF-kB Cancer Research Results
NF-kB, Nuclear factor kappa B: Click to Expand ⟱
| Source: HalifaxProj(inhibit) |
| Type: |
NF-kB signaling
Nuclear factor kappa B (NF-κB) is a transcription factor that plays a crucial role in regulating immune response, inflammation, cell proliferation, and survival.
NF-κB is often found to be constitutively active in many types of cancer cells. This persistent activation can promote tumorigenesis by enhancing cell survival, proliferation, and metastasis.
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Scientific Papers found: Click to Expand⟱
| - |
Review, |
IBD, |
NA |
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Review, |
Colon, |
NA |
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AntiCan↑, TumAuto↑, AIF↑, tumCV↓, TumCCA↑, *NF-kB?, ROS↑, TumCP↓, TumMeta↓, P53↑, BAX↑,
Showing Research Papers: 1 to 1 of 1
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress(tgid=1) ⓘ
ROS↑, 1,
Cell Death(tgid=5) ⓘ
AIF↑, 1, BAX↑, 1,
Transcription & Epigenetics(tgid=7) ⓘ
tumCV↓, 1,
Autophagy & Lysosomes(tgid=9) ⓘ
TumAuto↑, 1,
DNA Damage & Repair(tgid=10) ⓘ
P53↑, 1,
Cell Cycle & Senescence(tgid=11) ⓘ
TumCCA↑, 1,
Proliferation, Differentiation & Cell State(tgid=12) ⓘ
TumCP↓, 1,
Migration(tgid=13) ⓘ
TumMeta↓, 1,
Functional Outcomes(tgid=23) ⓘ
AntiCan↑, 1,
Total Targets: 10
Pathway results for Effect on Normal Cells:
Immune & Inflammatory Signaling(tgid=16) ⓘ
NF-kB?, 1,
Total Targets: 1
Scientific Paper Hit Count for: NF-kB, Nuclear factor kappa B
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:1 prod#:% Target#:214 State#:% Dir#:0
wNotes=0 sortOrder:rid,rpid
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