Inflam Cancer Research Results

Inflam, inflammation: Click to Expand ⟱
Source:
Type:
Cancer and inflammation are closely linked, with chronic inflammation contributing to the development and progression of cancer. Various inflammatory mediators and cells are involved in this process.


Scientific Papers found: Click to Expand⟱
6703- DFC,    Molecular docking of anti-inflammatory drug diclofenac with metabolic targets: Potential applications in cancer therapeutics.
- Analysis, Var, NA
*Inflam?, *COX1↓, *COX2/PTGS2↓, GLUT1↓, MCT4↓, LDHA↓, ABCG2↓, MDM2↓, MRP1/ABCC1↓, SOD2↓, Myc↓, β-catenin/ZEB1↓, VEGF↓, IKKα↓, cJun↓, E2Fs↓,
6824- EMD,    Neuroprotective, Anti-Inflammatory and Antifibrillogenic Offerings by Emodin against Alzheimer’s Dementia: A Systematic Review
- Review, AD, NA
*Inflam?, *antiOx↑, *tau↓, *Aβ↓, *neuroP↑, *ROS↓, *memory↑, *cognitive↑, *other↝, *AChE↓, *BACE/β-secretase↓, *LC3II↓, *Beclin-1/ATG6↓, *p‑tau↓, *CREB↑, *HNE↓, *BioAv↓, *BioAv↝, *BioAv↑, *BioAv↑, *BioAv↑, *BioAv↑, BioAv↑, *HO-1↑, *PKCδ↑, *Akt↑, *NLRP3↓, *NF-kB↓, *TLR3↓,
8580- FS,    Anti-Cancer Properties of Flaxseed Proteome
- Review, Var, NA
TumCP↓, Apoptosis↑, TumMeta↑, *Inflam?, *ROS?, *TNF-α?, *IL6?, TumCCA↑, Imm↑, ChemoSen↑, Synergy↑,
7845- ISQ,    Isoquercitrin, ingredients in Tetrastigma hemsleyanum Diels et Gilg, inhibits hepatocyte growth factor/scatter factor-induced tumor cell migration and invasion
- vitro+vivo, Bladder, NBT-II
p‑MET↓, TumCMig↓, TumCI↓, EMT↓, *Inflam?, *antiOx↑, *ROS↓, *lipid-P↓, *neuroP↑,
8531- Matr,    Matrine: A review of its pharmacology, pharmacokinetics, toxicity, clinical application and preparation researches
- Review, Nor, NA
*AntiCan?, *Inflam?, *Bacteria↓,
2196- SK,    Research progress in mechanism of anticancer action of shikonin targeting reactive oxygen species
- Review, Var, NA
*ALAT↓, *AST↓, *Inflam?, *EMT↑, ROS?, TrxR1↓, PERK↑, eIF2α↑, ATF4↑, CHOP/DDIT3↑, IRE1↑, JNK↑, eff↝, DR5↑, Glycolysis↓, PKM2↓, ChemoSen↑, GPx4↓, HO-1↑,

Showing Research Papers: 1 to 6 of 6

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 6

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

GPx4↓, 1,   HO-1↑, 1,   ROS?, 1,   SOD2↓, 1,   TrxR1↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

Glycolysis↓, 1,   LDHA↓, 1,   MCT4↓, 1,   PKM2↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 1,   DR5↑, 1,   MDM2↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

IKKα↓, 1,   JNK↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF4↑, 1,   cJun↓, 1,   Myc↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1,   eIF2α↑, 1,   IRE1↑, 1,   PERK↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

E2Fs↓, 1,   TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

TumCP↓, 1,  

Migration(tgid=13) ⓘ

EMT↓, 1,   p‑MET↓, 1,   TumCI↓, 1,   TumCMig↓, 1,   TumMeta↑, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

GLUT1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Imm↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ABCG2↓, 1,   BioAv↑, 1,   ChemoSen↑, 2,   eff↝, 1,   MRP1/ABCC1↓, 1,   Synergy↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

Myc↓, 1,  
Total Targets: 40

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 2,   HNE↓, 1,   HO-1↑, 1,   lipid-P↓, 1,   ROS?, 1,   ROS↓, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↑, 1,   CREB↑, 1,   PKCδ↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↝, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,   LC3II↓, 1,  

Migration(tgid=13) ⓘ

EMT↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 1,   COX2/PTGS2↓, 1,   IL6?, 1,   Inflam?, 6,   NF-kB↓, 1,   NLRP3↓, 1,   TLR3↓, 1,   TNF-α?, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,   BACE/β-secretase↓, 1,   tau↓, 1,   p‑tau↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 4,   BioAv↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AST↓, 1,   IL6?, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan?, 1,   cognitive↑, 1,   memory↑, 1,   neuroP↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,  
Total Targets: 38

Scientific Paper Hit Count for: Inflam, inflammation
1 Diclofenac
1 Emodin
1 Flaxseed/Linseed
1 isoquercitrin
1 Matrine
1 Shikonin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:953  State#:%  Dir#:0
wNotes=0 sortOrder:rid,rpid

 

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