Sepsis Cancer Research Results

Sepsis, Sepsis: Click to Expand ⟱
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Type:
Sepsis is a life-threatening medical condition that occurs when the body’s response to an infection causes widespread inflammation. This uncontrolled inflammatory response can lead to tissue damage, organ failure, and, in severe cases, death.

-Treatment options PKM2, Glycolysis and HIF1α inhibitors.

-Chemotherapy, radiation therapy, and immunosuppressive drugs can further weaken the immune system, making patients more susceptible to infections that can lead to sepsis.

-AgNPs have demonstrated antimicrobial effects against a wide range of pathogens including bacteria, fungi, and viruses. Since infections are the primary trigger for sepsis, their ability to reduce microbial loads has been of significant interest.
Scientific Papers found: Click to Expand⟱
3456- ALA,    Renal-Protective Roles of Lipoic Acid in Kidney Disease
- Review, Nor, NA
*RenoP↑, *ROS↓, *antiOx↑, *Inflam↓, *Sepsis↓, *IronCh↑, *BUN↓, *creat↓, *TNF-α↓, *IL6↓, *IL1β↓, *MDA↓, *NRF2↑, *HO-1↑, *NQO1↑, *chemoP↑, *eff↑, *NF-kB↓,
2348- CAP,    Recent advances in analysis of capsaicin and its effects on metabolic pathways by mass spectrometry
- Analysis, Nor, NA
Warburg↓, *PKM2↓, *COX2/PTGS2↓, *Inflam↓, *Sepsis↓, *AMPK↑, *PKA↑, *mitResp↑, *FAO↑, *FASN↓, *PGM1?, *ATP↑, *ROS↓,
2347- CAP,    Capsaicin ameliorates inflammation in a TRPV1-independent mechanism by inhibiting PKM2-LDHA-mediated Warburg effect in sepsis
- in-vivo, Nor, NA - in-vitro, Nor, RAW264.7
*PKM2↓, *LDHA↓, *Warburg↓, *COX2/PTGS2↓, *Sepsis↓, *Inflam↓, *ECAR↓, *OCR↑,
3869- Carno,    Carnosine, Small but Mighty—Prospect of Use as Functional Ingredient for Functional Food Formulation
- Review, AD, NA - Review, Stroke, NA
*ROS↓, *IronCh↑, *AntiAge↑, *antiOx↑, *Inflam↓, *neuroP↑, *lipid-P↓, *toxicity↓, *NOX4↓, *SOD↑, *HNE↓, *IL6↓, *TNF-α↓, *IL1β↓, *Sepsis↓, *Stroke↓, *GABA↝, *Aβ↓, Glycolysis↓, AntiTum↑, p‑Akt↓, TumCCA↑, angioG↓, VEGFR2/KDR/Flk1↓, NF-kB↓,
6650- Cen,    Therapeutic Potential of Centella asiatica and Its Triterpenes: A Review
- Review, AD, NA
*BioAv↝, *BioAv↝, *MDA↓, *GSH↑, *SOD↑, *AChE↓, *memory↑, *Ki-67↑, *Catalase↑, *PI3K↑, *BDNF↑, *NGF↑, *ROS↓, *NRF2↑, *HO-1↑, *NQO1↑, *ATP↑, *OCR↑, *TNF-α↓, *PP2A↑, *GSK‐3β↓, *Bcl-2↑, *TrkB↑, *NOTCH1↑, *SOX2↑, *Nestin↑, *MDA↓, *MAOA↓, *MAOB↓, *GPx↑, *cognitive↑, *ROS↓, *neuroP↑, *glucose↓, *ALAT↓, *AST↓, *PFK↓, *Weight↓, *Inflam↓, *AntiDiabetic↑, *Obesity↓, *Wound Healing↑, *cardioP↑, *GutMicro↑, *Sepsis↓, *BioAv↑,
6421- CUR,    Curcumin simultaneously improves mitochondrial dynamics and myocardial cell bioenergy after sepsis via the SIRT1-DRP1/PGC-1α pathway
- in-vivo, Nor, NA
*SIRT1↓, *PGC-1α↑, *NRF2↑, *DRP1/DNM1L↓, *Sepsis↓, *OS↑, *cardioP↑,
6282- DL,    Limonene Exerts Anti-Inflammatory Effect on LPS-Induced Jejunal Injury in Mice by Inhibiting NF-κB/AP-1 Pathway
- in-vivo, IBD, NA
*RenoP↑, *creat↓, *Inflam↓, *TNF-α↓, *IL1β↓, *COX2/PTGS2↓, *ROS↓, *NRF2↑, *GastroP↑, *TLR4↓, *NF-kB↓, *AP-1↓, *Sepsis↓,
7228- EGb 761,    Current Perspectives on the Beneficial Role of Ginkgo biloba in Neurological and Cerebrovascular Disorders
- Review, AD, NA
*Dose↝, *PAF↑, *AntiAg↑, *BloodF↑, *Inflam↓, *neuroP↑, *Stroke↓, *Dose↝, *Sepsis↓, *memory↑,
6877- FA,    The protective role of ferulic acid on sepsis-induced oxidative damage in Wistar albino rats
- in-vivo, Nor, NA
*antiOx↑, *Inflam↓, *AntiCan↑, *hepatoP↑, *DNAdam↓, *Sepsis↓, *MDA↓, *GSH↑, *GPx↑, *ROS↓,
7482- H2,    Molecular Hydrogen Therapy: Mechanisms, Delivery Methods, Preventive, and Therapeutic Application
- Review, Var, NA - Review, IBD, NA - Review, Stroke, NA - Review, Sepsis, NA - Review, AD, NA
Dose↝, *Inflam↓, *IL1β↓, *IL6↓, *TNF-α↓, *neuroP↑, *mTOR↓, *IL10↑, *TGF-β↑, *Sepsis↓, *NRF2↑, *antiOx↑, *Catalase↑, *SOD↑, *GPx↑, *ROS↓, *HO-1↑, *PI3K↑, *Akt↑, *hepatoP↑, *MPO↓, *cardioP↑, CDK4↓, CDK6↑, CD47↓, PI3K↓, Akt↓, Hif1a↓, selectivity↑, *MMP↑, *ATP↑, *ER Stress↓, *CHOP/DDIT3↓, *Casp12↓, *GRP78/BiP↓, *p38↓, *p‑JNK↓, *LC3‑Ⅱ/LC3‑Ⅰ↑, *p‑eIF2α↓, *ATF4↓, *XBP-1↓, *Imm↑, *IFN-γ↓, *IL4↓, *GranB/GZMB↓, NK cell↑, radioP↑, *CD4+↑, CD8+↑, *Dose↝, *other↑, *Dose↝, *antiPs↑, *BioAv↝, *GutMicro↑, Dose↝, *IBI↑, TumCP↓, TumCI↓, TumCMig↓, CD8+↑, PGC-1α↑, Akt↓, SCD1↓, *MDA↓, Synergy↑, *APP↓, *BACE/β-secretase↓, *Aβ↓, *cognitive↑, *neuroP↑, NP/CIPN↓, *Stroke↓, *NLRP3↓, *ALAT↓, *AST↓, *LPS↓, *hepatoP↑, chemoP↑, *creat↓, *Urea↓, *RenoP↑, *eff↑, Apoptosis↑, XIAP↓, IAP2/BIRC3↓, TumVol↓, MALAT1↓, EZH2↓, miR-124-3p↓, eff↑, ChemoSen↑, *compII↑, *compIII↑, *LDL↓, *Obesity↓, QoL↑, PFS↑, *antiAll↑,
7927- H2,    Hydrogen gas (XEN) inhalation ameliorates airway inflammation in asthma and COPD patients
- Human, Asthma, NA
*IL8↓, *IL4↓, *IL6↓, *Inflam↓, *Sepsis↓, *Stroke↓, *antiOx↑, *toxicity↓, *antiAll↑,
3787- H2,    Hydrogen, a Novel Therapeutic Molecule, Regulates Oxidative Stress, Inflammation, and Apoptosis
- Review, AD, NA
*Inflam↓, *antiOx↑, *ROS↓, *other↝, *NF-kB↓, *IL2↓, *IL6↓, *TNF-α↓, *HO-1↑, Apoptosis↑, TumAuto↑, *Sepsis↓, *NLRP3↓, Pyro↑,
3770- H2,    Role of Molecular Hydrogen in Ageing and Ageing-Related Diseases
- Review, AD, NA - Review, Park, NA
*antiOx↑, *NRF2↑, *HO-1↑, *Inflam↓, *neuroP↑, *cardioP↑, *other↓, *ROS↓, *NADPH↓, *Catalase↑, *GPx1↑, *NO↓, *mt-ROS↓, *SIRT3↑, *SIRT1↑, *TLR4↓, *mTOR↓, *cognitive↑, *Sepsis↓, *PTEN↓, *Akt↓, *NLRP3↓, *AntiAg↑, *IL6↓, *TNF-α↓, *IL1β↓, *MDA↓, *memory↑, *FOXO3↑, TumCG↓, *LDL↓,
3773- H2,    Role and mechanism of molecular hydrogen in the treatment of Parkinson’s diseases
- Review, Park, NA
*neuroP↑, *antiOx↑, *Inflam↓, *ROS↓, *NADPH↓, *NRF2↑, *BBB↑, *IL1β↓, *IL6↓, *TNF-α↓, *NF-kB↓, *NLRP3↓, *Sepsis↓, *p‑mTOR↓, *AMPK↑, *SIRT1↑, *HO-1↑,
2515- H2,    Recent Advances in Studies of Molecular Hydrogen against Sepsis
- Review, Sepsis, NA
*Sepsis↓, *Inflam↓, *antiOx↑, *ROS↓, *NADPH↓,
2508- H2,    Molecular hydrogen is a promising therapeutic agent for pulmonary disease
- Review, Var, NA - Review, Sepsis, NA
*ROS↓, eff↝, *Inflam↓, *NRF2↑, *HO-1↑, *SOD↑, *Catalase↑, *MPO↑, *ASK1↓, *NADPH↓, *Sepsis↓, *HMGB1↓, ROS↑, NLRP3↑, GSDMD↑, chemoP↑, eff↑, *antiAll↑,
7567- HYP,    Hyperoside: A review on its sources, biological activities, and molecular mechanisms
- Review, Var, NA
*AntiCan↑, *Bacteria↓, *AntiViral↑, *antiD↓, *RenoP↑, *hepatoP↑, *eff↑, *Sepsis↓, *AntiArt↑, *Stroke↓, TumCMig↓, TumCI↓, MTA1↓, TIMP2↓, MMP2↓, MMP↓, Cyt‑c↑, Akt↓, mTOR↓, P70S6K↓, TumAuto↑, PD-L1↓, TNF-α↓, IL1β↓, IL6↓, IL8↓, Bcl-2↓, Bcl-xL↓, BAX↑, BAD↑, Bak↑, VEGF↓, Casp3↑, Casp8↑, P53↑, GSH↓, SOD↓, Catalase↓, TAC↓, XIAP↓, ROS↓, NF-kB↓, TLR4↓, P-gp/ABCB1↓, LRP1↓, Fas↑, p27/CDKN1B↑, *cardioP↑, *AntiThr↑, *PAI-1/SERPINE1↓, *BUN↓, *ALAT↓, *AST↓, *neuroP?,
8135- LF,    Lactoferrin-A Regulator of Iron Homeostasis and Its Implications in Cancer
- Review, Var, NA - Review, AD, NA
IronCh↑, ROS↓, Imm↑, Inflam↓, *BBB↑, Iron↝, *Fenton↓, *ROS↓, *TAC↑, *SOD↑, *GPx↑, *GSH↑, *TBARS↓, *PTEN↓, *tau↓, *MAPK↓, *Aβ42↓, *Apoptosis↓, *Casp3↓, *Akt↑, *GutMicro↑, *Sepsis↓, *anemia↓, *IL6↓, *FPN↑, *TfR1/CD71↑, *Ferritin↓, *HemoG↑, *RBC↑, *eff↑, *BioAv↓, *BioAv↑, *BioAv↝, *ChemoSen↑, *BioAv↑, Ferroptosis↑,
8377- LT,    Luteolin: exploring its therapeutic potential and molecular mechanisms in pulmonary diseases
- Review, Asthma, NA
*PI3K↑, *Akt↑, *Inflam↓, *ROS↓, *BioAv↓, *RenoP↑, *cardioP↑, *neuroP↑, *antiAll↑, *AntiDiabetic↑, *hepatoP↑, *AntiThr↑, *toxicity↓, *IL10↓, *Sepsis↓, *TNF-α↓, *ROS↓, *GSH↑, *Catalase↑, *SOD↑, *MDA↓, *lipid-P↓, *IL4↓, *IL5↓, *PGE2↓, *PI3K↑, *Akt↑, *mTOR↑, *Beclin-1/ATG6↓, *Mucositis↓, *PLA2↓, STAT3↓, PD-L1↓, miR-34a↓, Casp3↑, Casp9↑, Bcl-2↓, BAX↑, Bax:Bcl2↑, Apoptosis↑, ROS↑, EMT↓, E-cadherin↓, DR5↑, LIMK1↓, Pain↓,
8728- M-Blu,    Neurometabolic mechanisms for memory enhancement and neuroprotection of methylene blue
- Review, AD, NA
*Dose↝, *antiOx↑, *mitResp↑, *neuroP↑, *memory↑, *CellMemb↑, *BBB↑, *other↝, *compV↑, *OCR↑, *ROS↓, *Sepsis↓, *NO↓, *RNS↓, *memory↑, *tau↓, *CX43/GJA1↑, *THBD↑, *CARTPT↑,
3257- PBG,    The Potential Use of Propolis as a Primary or an Adjunctive Therapy in Respiratory Tract-Related Diseases and Disorders: A Systematic Scoping Review
- Review, Var, NA
CDK4↓, CDK6↓, pRB↓, ROS↓, TumCCA↑, P21↑, PI3K↓, Akt↓, EMT↓, E-cadherin↑, Vim↓, *COX2/PTGS2↓, *MPO↓, *MDA↓, *TNF-α↓, *IL6↓, *Catalase↑, *SOD↑, *AST↓, *ALAT↓, *IL1β↓, *IL10↓, *GPx↓, *TLR4↓, *Sepsis↓, *IFN-γ↑, *GSH↑, *NRF2↑, *α-SMA↓, *TGF-β↓, *IL5↓, *IL6↓, *IL8↓, *PGE2↓, *NF-kB↓, *MMP9↓,
3349- QC,    Sepsis_via_Inhibition_of_Reactive_Oxygen_Species_ROS_and_Downregulation_of_High_Mobility_Group_Box_1_HMGB1_Protein_Expression">Quercetin Exerted Protective Effects in a Rat Model of Sepsis via Inhibition of Reactive Oxygen Species (ROS) and Downregulation of High Mobility Group Box 1 (HMGB1) Protein Expression
- in-vivo, Sepsis, NA
*Sepsis↓, *ROS↓, *SOD↑, *Catalase↑, *HMGB1↓, *Inflam↓, *TAC↑,
3365- QC,    Quercetin attenuates sepsis-induced acute lung injury via suppressing oxidative stress-mediated ER stress through activation of SIRT1/AMPK pathways
- in-vivo, Sepsis, NA
*ER Stress↓, *PDI↓, *CHOP/DDIT3↓, *GRP78/BiP↓, *ATF6↓, *PERK↓, *IRE1↓, *MMP↑, *SOD↑, *ROS↓, *MDA↓, *SIRT1↑, *AMPK↑, *Sepsis↓,
2339- QC,    Quercetin protects against LPS-induced lung injury in mice via SIRT1-mediated suppression of PKM2 nuclear accumulation
- in-vivo, Nor, NA
*Inflam↓, *antiOx↑, *NLRP3↓, *Sepsis↓, *PKM2↓, *SIRT1↓,
3021- RosA,    Rosmarinic acid ameliorates septic-associated mortality and lung injury in mice via GRP78/IRE1α/JNK pathway
- in-vivo, Sepsis, NA
*eff↑, *SOD↑, *MDA↓, *GRP78/BiP↓, *IRE1↓, *JNK↓, *Sepsis↓,
3023- RosA,    Rosmarinic acid alleviates septic acute respiratory distress syndrome in mice by suppressing the bronchial epithelial RAS-mediated ferroptosis
- in-vivo, Sepsis, NA
*GPx4↑, *Inflam↓, *ER Stress↓, *Ferroptosis↓, *Sepsis↓, *GRP78/BiP↓, *IRE1↓, JNK↓,
3024- RosA,    rmMANF prevents sepsis-associated lung injury via inhibiting endoplasmic reticulum stress-induced ferroptosis in mice
- in-vivo, Sepsis, NA
*Ferroptosis↓, *GRP78/BiP↓, *PERK↓, *ATF4↓, *Sepsis↓, *GSH↑, *SOD↑, *Catalase↑,
4607- SeNPs,  AgNPs,    A Review on synthesis and their antibacterial activity of Silver and Selenium nanoparticles against biofilm forming Staphylococcus aureus
- Review, Var, NA
*Bacteria↓, *eff↑, ROS↑, *Dose↝, *eff↑, toxicity↝, *Sepsis↓, *other↝, eff↑,
2354- SK,    PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation
- in-vivo, Sepsis, NA
PKM2↓, *PKM2↓, *IL1β↓, *IL18↓, *HMGB1↓, *Casp1↓, *NLRP3↓, *AIM2↓, *p‑eIF2α↓, *Sepsis↓,

Showing Research Papers: 1 to 29 of 29

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 29

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

Catalase↓, 1,   GSH↓, 1,   Iron↝, 1,   ROS↓, 3,   ROS↑, 3,   SOD↓, 1,   TAC↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

PGC-1α↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

Glycolysis↓, 1,   PKM2↓, 1,   SCD1↓, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 3,   BAD↑, 1,   Bak↑, 1,   BAX↑, 2,   Bax:Bcl2↑, 1,   Bcl-2↓, 2,   Bcl-xL↓, 1,   Casp3↑, 2,   Casp8↑, 1,   Casp9↑, 1,   Cyt‑c↑, 1,   DR5↑, 1,   Fas↑, 1,   Ferroptosis↑, 1,   GSDMD↑, 1,   IAP2/BIRC3↓, 1,   Pyro↑, 1,   XIAP↓, 2,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 4,   p‑Akt↓, 1,   JNK↓, 1,   LIMK1↓, 1,   mTOR↓, 1,   P70S6K↓, 1,   PI3K↓, 2,   STAT3↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

EZH2↓, 1,   miR-124-3p↓, 1,   miR-34a↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

TumAuto↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

P53↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK4↓, 2,   CDK6↓, 1,   CDK6↑, 1,   P21↑, 1,   p27/CDKN1B↑, 1,   pRB↓, 1,   TumCCA↑, 2,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

TumCG↓, 1,   TumCP↓, 1,  

Migration(tgid=13) ⓘ

E-cadherin↓, 1,   E-cadherin↑, 1,   EMT↓, 2,   LRP1↓, 1,   MALAT1↓, 1,   MMP2↓, 1,   MTA1↓, 1,   TIMP2↓, 1,   TumCI↓, 2,   TumCMig↓, 2,   Vim↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   Hif1a↓, 1,   VEGF↓, 1,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

MMP↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD47↓, 1,   CD8+↑, 2,   IL1β↓, 1,   IL6↓, 1,   IL8↓, 1,   Imm↑, 1,   Inflam↓, 1,   NF-kB↓, 2,   NK cell↑, 1,   NLRP3↑, 1,   PD-L1↓, 2,   TLR4↓, 1,   TNF-α↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

ChemoSen↑, 1,   Dose↝, 2,   eff↑, 3,   eff↝, 1,   P-gp/ABCB1↓, 1,   selectivity↑, 1,   Synergy↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

EZH2↓, 1,   IL6↓, 1,   PD-L1↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiTum↑, 1,   chemoP↑, 2,   NP/CIPN↓, 1,   Pain↓, 1,   PFS↑, 1,   QoL↑, 1,   radioP↑, 1,   toxicity↝, 1,   TumVol↓, 1,  
Total Targets: 101

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 11,   Catalase↑, 8,   Fenton↓, 1,   GPx↓, 1,   GPx↑, 4,   GPx1↑, 1,   GPx4↑, 1,   GSH↑, 6,   HNE↓, 1,   HO-1↑, 7,   lipid-P↓, 2,   MDA↓, 10,   MPO↓, 2,   MPO↑, 1,   NOX4↓, 1,   NQO1↑, 2,   NRF2↑, 9,   RNS↓, 1,   ROS↓, 19,   mt-ROS↓, 1,   SOD↑, 11,   TAC↑, 2,   TBARS↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   FPN↑, 1,   IronCh↑, 2,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compII↑, 1,   compIII↑, 1,   compV↑, 1,   DRP1/DNM1L↓, 1,   mitResp↑, 2,   OCR↑, 3,   PGC-1α↑, 1,   SIRT3↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 4,   AMPK↑, 3,   ATP↑, 3,   ECAR↓, 1,   FAO↑, 1,   FASN↓, 1,   glucose↓, 1,   GSK‐3β↓, 1,   LDHA↓, 1,   LDL↓, 2,   NADPH↓, 4,   PFK↓, 1,   PGM1?, 1,   PKM2↓, 4,   PLA2↓, 1,   SIRT1↓, 2,   SIRT1↑, 3,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 1,   ASK1↓, 1,   Bcl-2↑, 1,   Casp1↓, 1,   Casp12↓, 1,   Casp3↓, 1,   Ferroptosis↓, 2,   GranB/GZMB↓, 1,   p38↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   Akt↑, 4,   JNK↓, 1,   p‑JNK↓, 1,   MAPK↓, 1,   mTOR↓, 2,   mTOR↑, 1,   p‑mTOR↓, 1,   PI3K↑, 4,   PKA↑, 1,   PP2A↑, 1,   PTEN↓, 2,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 2,   ATF4↓, 2,   FOXO3↑, 1,   other↓, 1,   other↑, 1,   other↝, 3,   SOX2↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↓, 1,   CHOP/DDIT3↓, 2,   p‑eIF2α↓, 2,   ER Stress↓, 3,   GRP78/BiP↓, 5,   IRE1↓, 3,   PDI↓, 1,   PERK↓, 2,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↓, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

Ki-67↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

Ki-67↑, 1,   Nestin↑, 1,   NOTCH1↑, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 2,   AP-1↓, 1,   MMP9↓, 1,   PAI-1/SERPINE1↓, 1,   TGF-β↓, 1,   TGF-β↑, 1,   α-SMA↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↓, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 3,   CellMemb↑, 1,   CX43/GJA1↑, 1,   GastroP↑, 1,   IBI↑, 1,   MMP↑, 2,   THBD↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

AIM2↓, 1,   CD4+↑, 1,   COX2/PTGS2↓, 4,   HMGB1↓, 3,   IFN-γ↓, 1,   IFN-γ↑, 1,   IL10↓, 2,   IL10↑, 1,   IL18↓, 1,   IL1β↓, 8,   IL2↓, 1,   IL4↓, 3,   IL5↓, 2,   IL6↓, 10,   IL8↓, 2,   Imm↑, 1,   Inflam↓, 19,   LPS↓, 1,   NF-kB↓, 5,   NLRP3↓, 6,   PAF↑, 1,   PGE2↓, 2,   TLR4↓, 3,   TNF-α↓, 10,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,   BDNF↑, 1,   CARTPT↑, 1,   GABA↝, 1,   MAOA↓, 1,   MAOB↓, 1,   NGF↑, 1,   TrkB↑, 1,  

Protein Aggregation(tgid=19) ⓘ

APP↓, 1,   Aβ↓, 2,   Aβ42↓, 1,   BACE/β-secretase↓, 1,   tau↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2,   BioAv↑, 3,   BioAv↝, 4,   ChemoSen↑, 1,   Dose↝, 6,   eff↑, 7,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 4,   anemia↓, 1,   AST↓, 4,   BloodF↑, 1,   BUN↓, 2,   creat↓, 3,   Ferritin↓, 1,   HemoG↑, 1,   IL6↓, 10,   RBC↑, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   antiAll↑, 4,   AntiArt↑, 1,   AntiCan↑, 2,   antiD↓, 1,   AntiDiabetic↑, 2,   antiPs↑, 1,   cardioP↑, 6,   chemoP↑, 1,   cognitive↑, 3,   hepatoP↑, 5,   memory↑, 5,   Mucositis↓, 1,   neuroP?, 1,   neuroP↑, 9,   Obesity↓, 2,   OS↑, 1,   RenoP↑, 5,   Stroke↓, 5,   toxicity↓, 3,   Weight↓, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 1,   Bacteria↓, 2,   GutMicro↑, 3,   Sepsis↓, 29,  
Total Targets: 192

Scientific Paper Hit Count for: Sepsis, Sepsis
7 Hydrogen Gas
3 Quercetin
3 Rosmarinic acid
2 Capsaicin
1 Alpha-Lipoic-Acid
1 Carnosine
1 Centella asiatica / Gotu kola → asiaticoside
1 Curcumin
1 D-limonene
1 Ginkgo biloba-EGb 761
1 Ferulic acid
1 Hyperoside
1 Lactoferrin/Talactoferrin
1 Luteolin
1 Methylene blue
1 Propolis -bee glue
1 Selenium NanoParticles
1 Silver-NanoParticles
1 Shikonin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:1264  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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