glucose Cancer Research Results

glucose, glucose: Click to Expand ⟱
Source:
Type:
Glucose
Scientific Papers found: Click to Expand⟱
3971- ACNs,    Blueberry Supplementation Improves Memory in Older Adults
- Human, AD, NA
*antiOx↑, *Inflam↓, *memory↑, *neuroP↑, *cognitive↑, *Mood↑, *glucose↓,
4549- AgNPs,    Silver nanoparticles: Synthesis, medical applications and biosafety
- Review, Var, NA - Review, Diabetic, NA
ROS↑, eff↑, other↝, DNAdam↑, EPR↑, eff↑, eff↑, TumMeta↓, angioG↓, *Bacteria↓, *eff↑, *AntiViral↑, *AntiFungal↑, eff↑, eff↑, TumCP↓, tumCV↓, P53↝, HIF-1↓, TumCCA↑, lipid-P↑, ATP↓, Cyt‑c↑, MMPs↓, PI3K↓, Akt↓, *Wound Healing↑, *Inflam↓, *Bone Healing↑, *glucose↓, *AntiDiabetic↑, *BBB↑,
7401- Amla,    The impact of Emblica Officinalis (Amla) on lipid profile, glucose, and C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
- Review, Nor, NA
*CRP↓, *glucose↓, *LDL↓, Dose↑,
3505- Bor,    Mineral requirements for mitochondrial function: A connection to redox balance and cellular differentiation
- Review, Nor, NA
*glucose↓, *creat↓, *SOD↑, *MMP↑, *ROS↓,
5842- CAP,    Capsaicin: Current Understanding of Its Mechanisms and Therapy of Pain and Other Pre-Clinical and Clinical Uses
- Review, Nor, NA - Review, Diabetic, NA
*Pain↓, *TRPV1↑, AMPK↑, ROS↑, TumCP↑, Apoptosis↑, TumCCA↑, Casp3↑, BAX↑, Bak↑, cl‑PARP↑, Bcl-2↓, RNS↑, *glucose↓, *Insulin↑, *BP↓, *AntiAg↑, ER Stress↑, Hif1a↓, chemoPv↑,
5824- CAP,    Pharmacokinetic and the effect of capsaicin in Capsicum frutescens on decreasing plasma glucose level
- Study, Diabetic, NA
*glucose↓, *Insulin↑, *Dose↑, *AntiDiabetic↑,
6650- Cen,    Therapeutic Potential of Centella asiatica and Its Triterpenes: A Review
- Review, AD, NA
*BioAv↝, *BioAv↝, *MDA↓, *GSH↑, *SOD↑, *AChE↓, *memory↑, *Ki-67↑, *Catalase↑, *PI3K↑, *BDNF↑, *NGF↑, *ROS↓, *NRF2↑, *HO-1↑, *NQO1↑, *ATP↑, *OCR↑, *TNF-α↓, *PP2A↑, *GSK‐3β↓, *Bcl-2↑, *TrkB↑, *NOTCH1↑, *SOX2↑, *Nestin↑, *MDA↓, *MAOA↓, *MAOB↓, *GPx↑, *cognitive↑, *ROS↓, *neuroP↑, *glucose↓, *ALAT↓, *AST↓, *PFK↓, *Weight↓, *Inflam↓, *AntiDiabetic↑, *Obesity↓, *Wound Healing↑, *cardioP↑, *GutMicro↑, *Sepsis↓, *BioAv↑,
6002- CGA,    Chlorogenic Acid: A Systematic Review on the Biological Functions, Mechanistic Actions, and Therapeutic Potentials
- Review, Var, NA - Review, Diabetic, NA - Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*neuroP↑, *Inflam↓, *antiOx↑, *cardioP↑, *NRF2↑, *AMPK↑, *SOD↑, *Catalase↑, *GSH↑, *GPx↑, *ROS↓, *TNF-α↓, *IL6↓, *NF-kB↓, *COX2/PTGS2↓, *glucose↓, *TRPC1↓, *Ca+2↓, *HO-1↑, *NF-kB↓, *PPARα↝, *Hif1a↓, *JNK↓, *BP↓, *AntiDiabetic↑, *hepatoP↑, *TLR4↓, *NRF2↑, *Casp↓, *neuroP↑, *Aβ↓, *LDH↓, *MDA↓, *memory↑, *AChE↓, *Stroke↓, EMT↝, N-cadherin↓, E-cadherin↑, TumCCA↑, ROS↑, p‑P53↑, HO-1↑, NRF2↑, ChemoSen↑, mtDam↑, Casp3↑, Casp9↑, PARP↑, Bax:Bcl2↑, TumCG↓, cycD1/CCND1↓, cMyc↓, CDK2↓, mitResp↓, Glycolysis↓, Hif1a↓, PCNA↓, p‑GSK‐3β↓, VEGF↓, PI3K↓, Akt↓, mTOR↓, OS↑,
6166- Cin,    Cinnamaldehyde--a potential antidiabetic agent
- in-vivo, Diabetic, NA
*glucose↓,
6216- CUR,    Role of Turmeric and Curcumin in Prevention and Treatment of Chronic Diseases: Lessons Learned from Clinical Trials
- Review, Var, NA
TumCG↓, angioG↓, EMT↓, TumCI↓, TumMeta↓, *GutMicro↑, *BioAv↓, *HO-1↑, *ROS↓, *COX2/PTGS2↓, *iNOS↓, PKCδ↓, EGFR↓, NF-kB↓, cJun↓, cFos↓, cMyc↓, Akt↓, PI3K↓, CDK4↓, *TNF-α↓, *CRP↓, *IL6↓, MMP9↓, VEGF↓, JAK↓, STAT↓, IL1↓, IL2↓, IL6↓, IL8↓, IL12↓, MCP1/CCL2↓, Apoptosis↑, ER Stress↑, 5LO↓, XO↓, *NRF2↑, *HO-1↑, *AChE↓, *neuroP↑, *glucose↓, *GLUT2↑, *GLUT3↑, *GLUT4↑, *GlucoseCon↑, *AMPK↑, *BMD↑, *MDA↓, *Synergy↑, Synergy↑, P53↑, BAX↑, DNAdam↑, Bcl-2↓, CSCs↓, ALDH↓, CD133↑,
8624- dietKeto,    Impact of ketogenic diets on cancer patient outcomes: a systematic review and meta-analysis
- Review, Var, NA
*Weight↓, *Insulin↓, *glucose↓, *fatigue↓, *Sleep↑, *LDL↓, *TC↓, *BHB↑, *ketosis↑, eff↑, CRP↓, Inflam↓, angioG↓,
2270- dietMet,    Methionine-restricted diet inhibits growth of MCF10AT1-derived mammary tumors by increasing cell cycle inhibitors in athymic nude mice
- in-vivo, Var, NA
Weight↓, TumVol↓, P21↑, p27/CDKN1B↑, *adiP↑, *glucose↓, *IGF-1↓, *FGF21↑, *OS↑, Ki-67↓, Casp3↑, cycD1/CCND1↓,
2269- dietMet,    Mechanisms of Increased In Vivo Insulin Sensitivity by Dietary Methionine Restriction in Mice
- in-vivo, Nor, NA
*adiP↑, *FGF↑, *Insulin↓, *glucose↓, *Akt↑, *GSH↓, *PTEN↓, *FGF21↑, *PIP3↑,
5068- dietSTF,    mTOR-autophagy axis regulation by intermittent fasting promotes skeletal muscle growth and differentiation
- in-vivo, Nor, NA
*glucose↓, ROS↑, LC3B↑, p62↓, p‑mTOR↓, p‑AMPK↑,
5071- dietSTF,    Unraveling the impact of intermittent fasting in cancer prevention, mitigation, and treatment: A narrative review
- Review, Var, NA - Review, AD, NA
Risk↓, TumCMig↓, IGF-1↓, TumAuto↑, Inflam↓, ChemoSen↑, Apoptosis↑, chemoP↑, *glucose↓, *AntiDiabetic↑, *cardioP↑, *LDL↓, *BP↓, *neuroP↑, *cognitive↑, *memory↑, *OS↑, *QoL↑, Imm↑, TumCG↓, ChemoSideEff↓, QoL↑,
3708- dietSTF,    Fasting as a Therapy in Neurological Disease
- Review, Nor, NA
*PGC-1α↑, *AMPK↑, *adiP↑, *glucose↓, *Insulin↓, *mTOR↓, *IL6↓, *TNF-α↓, *cognitive↑, *Inflam↓, *eff↑, *neuroP↑, ChemoSen↑, eff↓, chemoP↑, *eff↑,
6281- DL,    Applications of Limonene in Neoplasms and Non-Neoplastic Diseases
- Review, Var, NA - Review, AD, NA - Review, Diabetic, NA
*antiOx↑, AntiTum↑, *AntiDiabetic↑, *neuroP↑, *GastroP↑, *ROS↓, *toxicity↓, *BioAv↑, ChemoSen↑, BAX↑, P53↓, Bcl-2↓, iNOS↓, COX2/PTGS2↓, eff↑, ROS↑, TumCCA↑, cycD1/CCND1↓, CycB/CCNB1↓, TumCMig↓, *lipid-P↓, *GSH↑, *SOD↑, *GPx↑, *hepatoP↑, *glucose↓, *AGEs↓, *Obesity↓, *Aβ↓, *AChE↓,
3205- EGCG,    The Role of Epigallocatechin-3-Gallate in Autophagy and Endoplasmic Reticulum Stress (ERS)-Induced Apoptosis of Human Diseas
- Review, Var, NA - Review, AD, NA
Beclin-1/ATG6↑, ROS↑, Apoptosis↑, ER Stress↑, *Inflam↓, *cardioP↑, *antiOx↑, *LDL↓, *NF-kB↓, *MPO↓, *glucose↓, *ROS↓, ATG5↑, LC3B↑, MMP↑, lactateProd↓, VEGF↓, Zeb1↑, Wnt↑, IGF-1R↑, Fas↑, Bak↑, BAD↑, TP53↓, Myc↓, Casp8↓, LC3II↑, NOTCH3↓, Synergy↑, p‑Akt↓, PARP↑, *Cyt‑c↓, *BAX↓, *memory↑, *neuroP↑, *Ca+2?, GRP78/BiP↑, CHOP/DDIT3↑, ATF4↑, Casp3↑, Casp8↑, UPR↑,
6825- EMD,    Advances in the pharmacological effects and molecular mechanisms of emodin in the treatment of metabolic diseases
- Review, Nor, NA
*Inflam↓, *AntiTum↑, *Bacteria↓, *Imm↑, *glucose↓, *RenoP↑, *TLR4↓, *MyD88↓, *NLRP3↓, *NF-kB↓, *PI3K↓, *mTOR↓, *GSK‐3β↓, *Hif1a↓, *VEGF↓, *GutMicro↑, *Obesity↓, *AntiDiabetic↑, *AMPK↑, *PPARγ↑, *PPARγ↓, *toxicity↝, *hepatoP↑, *AST↓, *ALAT↓,
6323- Eug,    Eugenol: An Insight Into the Anticancer Perspective and Pharmacological Aspects
- Review, Var, NA - Review, Arthritis, NA
*AntiCan↑, *AntiDiabetic↑, *cardioP↑, *toxicity↝, *GutMicro↑, *neuroP↑, *BioAv⇅, *BioAv↝, *antiOx↑, *Inflam↑, *AntiArt↑, *TNF-α↓, *IL6↓, *IL10↓, *GSH↑, *GPx↑, *Catalase↑, *MDA↓, *TAC↑, TumCMig↓, TumCI↓, Akt↑, FOXO3↑, Casp3↑, Casp9↑, P21↑, angioG↓, TumCI↓, Apoptosis↑, NF-kB↓, Synergy↑, Synergy↑, ChemoSen↑, NA↑, Casp3↑, Casp9↑, *AntiDiabetic↑, *glucose↓, *ROS↓, *Inflam↓, *MDA↓, *GSH↑, *BioAv↑,
6981- Form,    Formononetin: a review of its source, pharmacology, drug combination, toxicity, derivatives, and drug delivery systems
- Review, Var, NA - Review, AD, NA - Review, PSA, NA
BioAv↝, *memory↑, *ROS↓, *AChE↓, *NF-kB↓, *Keap1↝, *NRF2↑, *Inflam↓, *PGC-1α↝, *HO-1↓, *p‑tau↓, *cognitive↑, *BDNF↑, *5HT↑, *Stroke↓, *PARP1↓, *AIF↓, *Casp3↓, NP/CIPN↓, *neuroP↑, *NGF↑, *TNF-α↓, *IL1β↓, *IL18↓, *IL6↓, *VCAM-1↓, *pol-M2 MC↑, *hepatoP↑, *AST↓, *ALAT↓, *LC3II↑, *Beclin-1/ATG6↑, *p62↑, *COX2/PTGS2↑, *MMP↑, *ATP↑, *GSH↑, *Catalase↑, *GPx↑, *MDA↓, *antiPs↑, *AntiDiabetic↑, *glucose↓, *Insulin↑, *GutMicro↑, *Obesity↓, COX2/PTGS2↓, cycD1/CCND1↓, TumCCA↑, EGFR↓, GSK‐3β↑, Mcl-1↓, *toxicity↓, TumCP↓, Hif1a↓, VEGF↓, ERK↓, LAMs↓, Cyt‑c↑, Casp9↑, Casp3↑, PARP↑, TumCD↑, mitA↑, BACH1↓, P53↓, ROS↑, PD-1↓, NF-kB↓, *Bacteria↓, *AntiViral↑, *mt-ROS?, *PI3K↓, *chemoP↑, ChemoSen↑, Synergy↑, *toxicity↓, *BioAv↑, *BioAv↑, *Synergy↑, *antiAll↑,
8585- FS,    Dietary flaxseed: Cardiometabolic benefits and its role in promoting healthy aging
- Review, Nor, NA
*cardioP↑, *Obesity↓, *lipidLev↓, *BP↓, *Inflam↓, *CRP↓, *IL6↓, *ROS↓, *hepatoP↑, *Ingr↝, *GutMicro↑, *Dose↑, *Ingr↝, *Ingr?, *CompStab↝, *MDA↓, *hs-CRP↓, *TNF-α↓, *AntiDiabetic↑, *ALAT↓, *AST↓, *GGT/CD224↓, *TG/TAG↓, *LDL↓, *HDL∅, *TC↓, *glucose↓, *Insulin↓, *SIRT1↑, *Dose↝, *Dose?,
8604- FSO,  VitD3,    An 8-Week Triple-Blind, Randomized, Placebo-Controlled Trial Evaluating High-Dose Vitamin D3 and Flaxseed Oil for Inflammation and Metabolic Health in Elderly Patients With Type 2 Diabetes: Implications for Clinical Management
- Trial, Diabetic, NA
*TAC↑, *Weight↓, *glucose↓, *Insulin↓, *TG/TAG↓, *TC↓, *QoL↑, *Pain↓, *toxicity↓, *Dose↝,
7341- Hne,    Preclinical evaluation of safety and potential of black hellebore extracts for cancer treatment
- Review, Var, NA
angioG↓, TumCP↓, *Inflam↓, *Bacteria↓, *glucose↓, *neuroP↓, *hepatoP↓, *Imm↝,
4005- K+,    Potassium
- Review, Nor, NA - Review, Stroke, NA
*Risk↓, *Dose↝, *Risk↓, *BMD↑, *glucose↓,
8295- lign,    Distribution, biosynthesis and therapeutic potential of lignans
- Review, Var, NA
*Ingr?, *BioAv↝, *antiOx↑, *AntiCan↑, *Inflam↓, *other?, Dose↝, AntiTum↑, pS2/TFF1↓, Bcl-2↓, IGF-1R↓, *radioP↑, *HO-1↑, GSTM1↑, NQO1↑, ChemoSen↑, *AntiDiabetic↑, *glucose↓, *GSH↑, *SOD↑, *MDA↓, *NO↓, *Bacteria↓, *AntiFungal↑,
4529- MAG,    Effectiveness of Magnolol, a Lignan from Magnolia Bark, in Diabetes, Its Complications and Comorbidities—A Review
- Review, Diabetic, NA
*AntiDiabetic↑, *glucose↓, *SOD↑, *Catalase↑, *ROS↓, *MDA↓, *GPx↑, *CYP2E1↓, *AGEs↓, *IL10↑, *neuroP↑, *GutMicro↑,
8556- Matr,    Matrine alleviates spatial learning and memory impairment in diabetic mice by inhibiting endoplasmic reticulum stress and through modulation of PK2/PKRs pathway
- in-vivo, AD, NA - in-vivo, Diabetic, NA
*AntiTum↑, *AntiDiabetic↑, *cardioP↑, *neuroP↑, *glucose↓, *Learn↑, *memory↑, *ER Stress↓, *GRP78/BiP↓, *CHOP/DDIT3↓, *ATF6↓, *Casp12↓, *PROK2↑, *PROKR1↑, *PROKR2↑,
8707- MET,    Metformin in therapeutic applications in human diseases: its mechanism of action and clinical study
- Review, Var, NA - Review, AD, NA
*BioAv↝, *cardioP↑, *Obesity↓, *neuroP↑, *toxicity↝, *Dose↝, *GutMicro↑, *AMPK↑, *glucose↓, *NLRP3↑, *Inflam↓, *Stroke↓, *Cartilage↑, FOXP3↑, TumAuto↑, mTOR↓, PD-L1↓, RadioS↑, ChemoSen↑, ROS↓, OXPHOS↓, compI↓, Glycolysis↝, TumCP↓, *BioAv↝, *AntiAge↑, *SIRT1↑, *cognitive↑, *Risk↓, Ki-67↓, Synergy↝, PFS∅, OS∅,
2492- MET,    The Metformin Mechanism on Gluconeogenesis and AMPK Activation: The Metabolite Perspective
- Review, Nor, NA
*glucose↓, *glucoNG↓, *AMPK↑,
2491- MET,    Metformin suppresses gluconeogenesis by inhibiting mitochondrial glycerophosphate dehydrogenase
- in-vivo, Nor, NA
*glucoNG↓, *glucose↓, *mitResp↓,
5795- MET,    Metformin: A Review of Potential Mechanism and Therapeutic Utility Beyond Diabetes
- Review, AD, NA - Review, Park, NA - Review, Diabetic, NA
*AntiDiabetic↑, *AMPK↑, *glyC↓, *ROS↓, *cardioP↑, *neuroP↑, *Half-Life↝, *toxicity↝, *BioAv↑, *glucose↓, *AGEs↓, AntiCan↑, Risk↓, TumCP↓, Apoptosis↑, TumCCA↑, cycD1/CCND1↓, pRB↓, p27/CDKN1B↓, mTOR↓, Casp↑, ROS↑, MMP↓, ChemoSen↑, *hepatoP↑, *CRM↑, *Insulin↓,
8922- MP,    A Comprehensive Review of the Therapeutic Potential of Mucuna Pruriens
- Review, Park, NA
*Inflam↓, *AntiBio↑, *neuroP?, *Ingr↝, *Ingr↝, *AntiDiabetic↑, *hepatoP↑, *Imm↑, *Dose?, *neuroP↑, *glucose↓,
2333- RES,    Resveratrol regulates insulin resistance to improve the glycolytic pathway by activating SIRT2 in PCOS granulosa cells
- in-vitro, Nor, NA
*glucose↓, *Insulin↓, *IGFR↓, *IGF-1↓, *LDHA↑, *HK2↑, *PKM2↑, *Glycolysis↝, *SIRT2↑,
4446- SeNPs,    Antioxidant and Hepatoprotective Effects of Moringa oleifera-mediated Selenium Nanoparticles in Diabetic Rats.
- in-vivo, Diabetic, NA
*glucose↓, *antiOx↑, *GPx↑, *Catalase↑, *SOD↑, *ROS↓, *cardioP↑, *HDL↑, *LDL↓, *hepatoP↑, *TNF-α↓, *IL6↓, *IL1β↓, *lipid-P↓, *Inflam↓, *ALAT↓, *AST↓, *ALP↓, *Dose↝, *Dose↝,
3294- SIL,    Silymarin: a review on paving the way towards promising pharmacological agent
- Review, Nor, NA - Review, Arthritis, NA
*hepatoP↑, *Inflam↓, *chemoP↑, *glucose↓, *antiOx↑, *ROS↓, *ACC↓, *FASN↓, *radioP↑, *NF-kB↓, *TGF-β↓, *AST↓, *α-SMA↝, *Synergy↑, *neuroP↑, Synergy↑, ROS↓,
3150- VitC,    Vitamin C: A Review on its Role in the Management of Metabolic Syndrome
- Review, Obesity, NA
*glucose↓, *BG↓, *antiOx↑, *ROS↓,

Showing Research Papers: 1 to 37 of 37

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 37

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NA↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

HO-1↑, 1,   lipid-P↑, 1,   NQO1↑, 1,   NRF2↑, 1,   RNS↑, 1,   ROS↓, 2,   ROS↑, 8,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↓, 1,   mitResp↓, 1,   mtDam↑, 1,   OXPHOS↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 1,   AMPK↑, 1,   p‑AMPK↑, 1,   ATP↓, 1,   Glycolysis↓, 1,   Glycolysis↝, 1,   GSK‐3β↑, 1,   p‑GSK‐3β↓, 1,   lactateProd↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 6,   BAD↑, 1,   Bak↑, 2,   BAX↑, 3,   Bax:Bcl2↑, 1,   Bcl-2↓, 4,   Casp↑, 1,   Casp3↑, 7,   Casp8↓, 1,   Casp8↑, 1,   Casp9↑, 4,   Cyt‑c↑, 2,   Fas↑, 1,   iNOS↓, 1,   Mcl-1↓, 1,   pS2/TFF1↓, 1,   TumCD↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 3,   Akt↑, 1,   p‑Akt↓, 1,   EGFR↓, 2,   ERK↓, 1,   IGF-1R↓, 1,   IGF-1R↑, 1,   JAK↓, 1,   mTOR↓, 3,   p‑mTOR↓, 1,   PI3K↓, 3,   PKCδ↓, 1,   STAT↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

ATF4↑, 1,   cJun↓, 1,   cMyc↓, 2,   FOXO3↑, 1,   Myc↓, 1,   other↝, 1,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↑, 1,   ER Stress↑, 3,   GRP78/BiP↑, 1,   UPR↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

ATG5↑, 1,   Beclin-1/ATG6↑, 1,   LC3B↑, 2,   LC3II↑, 1,   p62↓, 1,   TumAuto↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 2,   P53↓, 2,   P53↑, 1,   P53↝, 1,   p‑P53↑, 1,   PARP↑, 3,   cl‑PARP↑, 1,   PCNA↓, 1,   TP53↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 1,   CycB/CCNB1↓, 1,   cycD1/CCND1↓, 5,   Ki-67↓, 2,   mitA↑, 1,   P21↑, 2,   p27/CDKN1B↓, 1,   p27/CDKN1B↑, 1,   pRB↓, 1,   TumCCA↑, 6,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 1,   CD133↑, 1,   cFos↓, 1,   CSCs↓, 1,   IGF-1↓, 1,   Ki-67↓, 2,   NOTCH3↓, 1,   TumCG↓, 3,   TumCP↓, 5,   TumCP↑, 1,   Wnt↑, 1,  

Migration(tgid=13) ⓘ

BACH1↓, 1,   E-cadherin↑, 1,   EMT↓, 1,   EMT↝, 1,   LAMs↓, 1,   MMP9↓, 1,   MMPs↓, 1,   N-cadherin↓, 1,   TumCI↓, 3,   TumCMig↓, 3,   TumMeta↓, 2,   Zeb1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 5,   HIF-1↓, 1,   Hif1a↓, 3,   VEGF↓, 4,  

Barriers & Transport(tgid=15) ⓘ

EPR↑, 1,   MMP↓, 1,   MMP↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 2,   FOXP3↑, 1,   IL1↓, 1,   IL12↓, 1,   IL2↓, 1,   IL6↓, 1,   IL8↓, 1,   Imm↑, 1,   Inflam↓, 2,   MCP1/CCL2↓, 1,   NF-kB↓, 3,   PD-1↓, 1,   PD-L1↓, 1,  

Protein Aggregation(tgid=19) ⓘ

XO↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↝, 1,   ChemoSen↑, 9,   Dose↑, 1,   Dose↝, 1,   eff↓, 1,   eff↑, 7,   GSTM1↑, 1,   RadioS↑, 1,   Synergy↑, 6,   Synergy↝, 1,  

Clinical Biomarkers(tgid=22) ⓘ

CRP↓, 1,   EGFR↓, 2,   IL6↓, 1,   Myc↓, 1,   PD-L1↓, 1,   TP53↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiTum↑, 2,   chemoP↑, 2,   chemoPv↑, 1,   ChemoSideEff↓, 1,   NP/CIPN↓, 1,   OS↑, 1,   OS∅, 1,   PFS∅, 1,   QoL↑, 1,   Risk↓, 2,   TumVol↓, 1,   Weight↓, 1,  
Total Targets: 161

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 9,   Catalase↑, 6,   GPx↑, 7,   GSH↓, 1,   GSH↑, 7,   HDL↑, 1,   HDL∅, 1,   HO-1↓, 1,   HO-1↑, 5,   Keap1↝, 1,   lipid-P↓, 2,   MDA↓, 10,   MPO↓, 1,   NQO1↑, 1,   NRF2↑, 5,   ROS↓, 15,   mt-ROS?, 1,   SOD↑, 7,   TAC↑, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

Insulin↓, 7,   Insulin↑, 3,   mitResp↓, 1,   OCR↑, 1,   PGC-1α↑, 1,   PGC-1α↝, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACC↓, 1,   adiP↑, 3,   ALAT↓, 5,   AMPK↑, 7,   ATP↑, 2,   BHB↑, 1,   CRM↑, 1,   FASN↓, 1,   glucoNG↓, 2,   glucose↓, 37,   GlucoseCon↑, 1,   glyC↓, 1,   Glycolysis↝, 1,   GSK‐3β↓, 2,   HK2↑, 1,   LDHA↑, 1,   LDL↓, 6,   lipidLev↓, 1,   PFK↓, 1,   PIP3↑, 1,   PKM2↑, 1,   SIRT1↑, 2,   SIRT2↑, 1,  

Cell Death(tgid=5) ⓘ

AIF↓, 1,   BAX↓, 1,   Bcl-2↑, 1,   Casp↓, 1,   Casp12↓, 1,   Casp3↓, 1,   Cyt‑c↓, 1,   iNOS↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↑, 1,   IGFR↓, 1,   JNK↓, 1,   mTOR↓, 2,   PI3K↓, 2,   PI3K↑, 1,   PP2A↑, 1,   PROKR1↑, 1,   PROKR2↑, 1,   PTEN↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other?, 1,   SOX2↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ATF6↓, 1,   CHOP/DDIT3↓, 1,   ER Stress↓, 1,   GRP78/BiP↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↑, 1,   LC3II↑, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

PARP1↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

Ki-67↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

FGF↑, 1,   IGF-1↓, 2,   Ki-67↑, 1,   Nestin↑, 1,   NOTCH1↑, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   Ca+2?, 1,   Ca+2↓, 1,   Cartilage↑, 1,   PROK2↑, 1,   TGF-β↓, 1,   α-SMA↝, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

Hif1a↓, 2,   NO↓, 1,   VCAM-1↓, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   GastroP↑, 1,   GLUT2↑, 1,   GLUT3↑, 1,   GLUT4↑, 1,   ketosis↑, 1,   MMP↑, 2,   TRPC1↓, 1,   TRPV1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 2,   COX2/PTGS2↑, 1,   IL10↓, 1,   IL10↑, 1,   IL18↓, 1,   IL1β↓, 2,   IL6↓, 7,   Imm↑, 2,   Imm↝, 1,   Inflam↓, 16,   Inflam↑, 1,   pol-M2 MC↑, 1,   MyD88↓, 1,   NF-kB↓, 6,   NLRP3↓, 1,   NLRP3↑, 1,   TLR4↓, 2,   TNF-α↓, 8,  

Cellular Microenvironment(tgid=17) ⓘ

GGT/CD224↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,   AChE↓, 5,   BDNF↑, 2,   MAOA↓, 1,   MAOB↓, 1,   NGF↑, 2,   TrkB↑, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 3,   Aβ↓, 2,   p‑tau↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

FGF21↑, 2,   PPARα↝, 1,   PPARγ↓, 1,   PPARγ↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 6,   BioAv⇅, 1,   BioAv↝, 6,   CompStab↝, 1,   CYP2E1↓, 1,   Dose?, 2,   Dose↑, 2,   Dose↝, 6,   eff↑, 3,   Half-Life↝, 1,   Synergy↑, 3,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 5,   ALP↓, 1,   AST↓, 6,   BG↓, 1,   BMD↑, 2,   BP↓, 4,   creat↓, 1,   CRP↓, 3,   hs-CRP↓, 1,   IL6↓, 7,   LDH↓, 1,   TC↓, 3,   TG/TAG↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiAge↑, 1,   antiAll↑, 1,   AntiArt↑, 1,   AntiCan↑, 2,   AntiDiabetic↑, 16,   antiPs↑, 1,   AntiTum↑, 2,   Bone Healing↑, 1,   cardioP↑, 10,   chemoP↑, 2,   cognitive↑, 6,   fatigue↓, 1,   hepatoP↓, 1,   hepatoP↑, 9,   Learn↑, 1,   memory↑, 7,   Mood↑, 1,   neuroP?, 1,   neuroP↓, 1,   neuroP↑, 17,   Obesity↓, 6,   OS↑, 2,   Pain↓, 2,   QoL↑, 2,   radioP↑, 2,   RenoP↑, 1,   Risk↓, 3,   Sleep↑, 1,   Stroke↓, 3,   toxicity↓, 4,   toxicity↝, 4,   Weight↓, 3,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↑, 1,   AntiFungal↑, 2,   AntiViral↑, 2,   Bacteria↓, 5,   GutMicro↑, 8,   Sepsis↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr?, 2,   Ingr↝, 4,  
Total Targets: 201

Scientific Paper Hit Count for: glucose, glucose
4 Metformin
3 diet Short Term Fasting
2 Capsaicin
2 diet Methionine-Restricted Diet
1 Anthocyanins
1 Silver-NanoParticles
1 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
1 Boron
1 Centella asiatica / Gotu kola → asiaticoside
1 Chlorogenic acid
1 Cinnamon
1 Curcumin
1 diet Ketogenic
1 D-limonene
1 EGCG (Epigallocatechin Gallate)
1 Emodin
1 Eugenol
1 Formononetin
1 Flaxseed/Linseed
1 Flaxseed Oil
1 Vitamin D3
1 Helleborus niger extracts – Christmas Rose
1 Potassium
1 SDG/lignans
1 Magnolol
1 Matrine
1 Mucuna pruriens/Velvet Bean
1 Resveratrol
1 Selenium NanoParticles
1 Silymarin (Milk Thistle) silibinin
1 Vitamin C (Ascorbic Acid)
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:1278  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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