TK1 Cancer Research Results

TK1, thymidine kinase 1: Click to Expand ⟱
Source:
Type:
Scientific Papers found: Click to Expand⟱
6563- Ger,  5-FU,    Geraniol, a component of plant essential oils, modulates DNA synthesis and potentiates 5-fluorouracil efficacy on human colon tumor xenografts
- vitro+vivo, Colon, SW-620 - in-vitro, Colon, Caco-2
TS↓, TK1↓, ChemoSen↑, TumVol↓, OS↑,
8097- KAE,    The Phenolic compound Kaempferol overcomes 5-fluorouracil resistance in human resistant LS174 colon cancer cells
- in-vitro, CRC, LS174T
ChemoSen↑, tumCV↓, Apoptosis↑, TumCCA↑, ROS↓, Casp3↑, Casp9↑, cl‑PARP↑, p‑STAT3↓, Akt↓, FOXO3↓, NF-kB↓, VEGF↓, TS↓, TK1↓,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1)

ROS↓, 1,  

Core Metabolism/Glycolysis(tgid=4)

TS↓, 2,  

Cell Death(tgid=5)

Akt↓, 1,   Apoptosis↑, 1,   Casp3↑, 1,   Casp9↑, 1,  

Transcription & Epigenetics(tgid=7)

tumCV↓, 1,  

DNA Damage & Repair(tgid=10)

cl‑PARP↑, 1,  

Cell Cycle & Senescence(tgid=11)

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12)

FOXO3↓, 1,   p‑STAT3↓, 1,   TK1↓, 2,  

Angiogenesis & Vasculature(tgid=14)

VEGF↓, 1,  

Immune & Inflammatory Signaling(tgid=16)

NF-kB↓, 1,  

Drug Metabolism & Resistance(tgid=21)

ChemoSen↑, 2,  

Functional Outcomes(tgid=23)

OS↑, 1,   TumVol↓, 1,  
Total Targets: 17

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: TK1, thymidine kinase 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:1503  State#:%  Dir#:1
wNotes=0 sortOrder:rid,rpid

 

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