NOD1 Cancer Research Results

NOD1, Nucleotide-binding oligomerization domain-containing protein 1: Click to Expand ⟱
Source:
Type:

NOD1 is a cytosolic pattern-recognition receptor in the NOD-like receptor family. It detects bacterial peptidoglycan fragments, particularly γ-D-glutamyl-meso-diaminopimelic acid, and signals mainly through RIPK2, activating NF-κB and MAPK pathways. It can also influence autophagy, inflammation, antimicrobial defence and cell death.
Scientific Papers found: Click to Expand⟱
7874- isoO,    Isoorientin protects lipopolysaccharide-induced acute lung injury in mice via modulating Keap1/Nrf2-HO-1 and NLRP3 inflammasome pathways
- in-vivo, Nor, NA
*ROS↓, *IL6↓, *NRF2↑, *HO-1↑, *Keap1↓, *NOD1↓, *NLRP3↓, *Casp1↓, *ASC↓, *IL1β↓, *Apoptosis↓,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

HO-1↑, 1,   Keap1↓, 1,   NRF2↑, 1,   ROS↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 1,   ASC↓, 1,   Casp1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

IL1β↓, 1,   IL6↓, 1,   NLRP3↓, 1,   NOD1↓, 1,  

Clinical Biomarkers(tgid=22) ⓘ

IL6↓, 1,  
Total Targets: 12

Scientific Paper Hit Count for: NOD1, Nucleotide-binding oligomerization domain-containing protein 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:1533  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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