NOD1 Cancer Research Results

NOD1, Nucleotide-binding oligomerization domain-containing protein 1: Click to Expand ⟱
Source:
Type:

NOD1 is a cytosolic pattern-recognition receptor in the NOD-like receptor family. It detects bacterial peptidoglycan fragments, particularly γ-D-glutamyl-meso-diaminopimelic acid, and signals mainly through RIPK2, activating NF-κB and MAPK pathways. It can also influence autophagy, inflammation, antimicrobial defence and cell death.
Scientific Papers found: Click to Expand⟱
6848- EVO,    Evodiamine: A Extremely Potential Drug Development Candidate of Alkaloids from Evodia rutaecarpa
- Review, Nor, NA
AntiTum↑, cardioP↑, Inflam↓, TumCP↓, TumCCA↑, Apoptosis↑, TumAuto↑, BioAv↓, toxicity↑, NF-kB↓, MAPK↓, NOD1↓, p‑Akt↓, BAX↑, cl‑Casp3↑, γH2AX↑, cl‑PARP↑, ROS↑, BBB↑, neuroP↑, BioAv↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

NOD1↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

ROS↑, 1,  

Cell Death(tgid=5) ⓘ

p‑Akt↓, 1,   Apoptosis↑, 1,   BAX↑, 1,   cl‑Casp3↑, 1,   MAPK↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

cl‑PARP↑, 1,   γH2AX↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 1,  

Migration(tgid=13) ⓘ

TumCP↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Inflam↓, 1,   NF-kB↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiTum↑, 1,   cardioP↑, 1,   neuroP↑, 1,   toxicity↑, 1,  
Total Targets: 21

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: NOD1, Nucleotide-binding oligomerization domain-containing protein 1
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:1533  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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