Stroke Cancer Research Results

Stroke, Stroke: Click to Expand ⟱
Source:
Type:

Stroke: A stroke, sometimes referred to as a brain attack arises if the blood flow is obstructed to a particular region of the brain or if the blood vessels in the brain rupture.



Scientific Papers found: Click to Expand⟱
7228- EGb 761,    Current Perspectives on the Beneficial Role of Ginkgo biloba in Neurological and Cerebrovascular Disorders
- Review, AD, NA
*Dose↝, *PAF↑, *AntiAg↑, *BloodF↑, *Inflam↓, *neuroP↑, *Stroke↓, *Dose↝, *Sepsis↓, *memory↑,
7236- EGb 761,    Neuroprotective effects of bilobalide, a component of the Ginkgo biloba extract (EGb 761), in gerbil global brain ischemia
- in-vivo, Stroke, NA
*Dose↑, *Stroke↓,
7196- EGb 761,    Ginkgo biloba extract EGb 761 in patients with dementia and a history of cerebral infarction-meta-analysis of pooled data from randomised clinical trials
- Review, AD, NA - Review, Stroke, NA
*neuroP↑, *cognitive↑, *Stroke↓, *toxicity↓, Dose↝,
6925- Flav,    Important Flavonoids and Their Role as a Therapeutic Agent
- Review, Nor, NA
AntiCan↑, *antiOx↑, *Inflam↓, *AntiViral↑, *neuroP↑, *cardioP↑, *AChE↓, *cognitive↑, Risk↓, *Stroke↓, *AntiDiabetic↑, *AntiFungal↑,
6981- Form,    Formononetin: a review of its source, pharmacology, drug combination, toxicity, derivatives, and drug delivery systems
- Review, Var, NA - Review, AD, NA - Review, PSA, NA
BioAv↝, *memory↑, *ROS↓, *AChE↓, *NF-kB↓, *Keap1↝, *NRF2↑, *Inflam↓, *PGC-1α↝, *HO-1↓, *p‑tau↓, *cognitive↑, *BDNF↑, *5HT↑, *Stroke↓, *PARP1↓, *AIF↓, *Casp3↓, NP/CIPN↓, *neuroP↑, *NGF↑, *TNF-α↓, *IL1β↓, *IL18↓, *IL6↓, *VCAM-1↓, *pol-M2 MC↑, *hepatoP↑, *AST↓, *ALAT↓, *LC3II↑, *Beclin-1↑, *p62↑, *COX2/PTGS2↑, *MMP↑, *ATP↑, *GSH↑, *Catalase↑, *GPx↑, *MDA↓, *antiPs↑, *AntiDiabetic↑, *glucose↓, *Insulin↑, *GutMicro↑, *Obesity↓, COX2/PTGS2↓, cycD1/CCND1↓, TumCCA↑, EGFR↓, GSK‐3β↑, Mcl-1↓, *toxicity↓, TumCP↓, Hif1a↓, VEGF↓, ERK↓, LAMs↓, Cyt‑c↑, Casp9↑, Casp3↑, PARP↑, TumCD↑, mitA↑, BACH1↓, P53↓, ROS↑, PD-1↓, NF-kB↓, *Bacteria↓, *AntiViral↑, *mt-ROS?, *PI3K↓, *chemoP↑, ChemoSen↑, eff↑, *toxicity↓, *BioAv↑, *BioAv↑, *eff↑,
7028- GA,    Gallic acid: Pharmacological activities and molecular mechanisms involved in inflammation-related diseases
- Review, Nor, NA
*toxicity↓, *Inflam↓, *NF-kB↓, AntiTum↑, Bacteria↓, *AntiDiabetic↑, *Obesity↓, *AntiBio↑, *Stroke↓, *NO↓, *PGE2↓, *IL6↓, *MAPK↓, *TNF-α↓, *IL1β↓, *MCP1/CCL2↓, *ICAM-1↓, *TIMP1↓,
7218- GBE,    Efficacy and Safety of Ginkgo biloba in Patients with Acute Ischemic Stroke: A Systematic Review and Meta-Analysis
- Review, Stroke, NA
*Stroke↓, *eff↑, *toxicity↓, *other?,
1188- GBE,    The potential of Ginkgo biloba in the treatment of human diseases and the relationship to Nrf2-mediated antioxidant protection
- Review, Stroke, NA
*NRF2↑, *ROS↓, *Stroke↓,
7199- GGB,    Ginkgolide B Promotes Angiogenesis After Oxygen-Glucose Deprivation by Regulating AKT1 in bEnd.3 Cells
- in-vitro, Stroke, NA
*neuroP↑, *VEGF↑, *AKT1↑, *angioG↑, *Stroke↓,
7140- GI,    Benefits of Ginger and Its Constituent 6-Shogaol in Inhibiting Inflammatory Processes
- Review, Var, NA
*Dose↝, *Inflam↓, *COX2/PTGS2↓, *iNOS↓, *NF-kB↓, *MAPK?, *HO-1↑, *PGE2↓, *TNF-α↓, *IL6↓, *IL1β↓, *IFN-γ↓, *MCP1/CCL2↓, *MIP2↓, *RANTES↓, *MPO↓, *NO↓, *Stroke↓, *BrainVol↑, *MDA↓, *ROS↓, *GSH↑, *NRF2↑, *antiOx↑, NLRP3↓, HDAC1↓,
7251- Gink,    Ginkgetin: A Promising Multitarget Agent for Diverse Diseases
- Review, Var, NA
*Inflam↓, *antiOx↓, AntiCan↑, *neuroP↑, *cardioP↑, *Bacteria↓, *ROS↓, *lipid-P↓, *NRF2↓, *Keap1↓, *NF-kB↓, *MAPK↓, MMP2↓, M2 MC↓, JAK2↓, STAT3↓, TumCP↓, Casp↑, ChemoSen↑, *BMD↑, *Aβ↓, *Stroke↓, *BioAv↓,
7260- Gink,    Ginkgetin: A natural biflavone with versatile pharmacological activities
- Review, Var, NA - Review, Stroke, NA - Review, AD, NA
*AntiCan↑, *Inflam↓, *AntiBio↑, *neuroP↑, *TumCCA↑, Apoptosis↑, TumAuto↑, iNOS↓, COX2/PTGS2↓, PGE2↓, NF-kB↓, PLA2↓, *neuroP↑, *Stroke↓, *AntiFungal↓, *Bacteria↓, Bcl-xL↓, Bcl-2↓, Casp9↑, Casp3↑, cl‑PARP↑, IL6↓, STAT3↓, JAK1↓, survivin↓, COX2/PTGS2↓, IAP1↓, MMP2↓, MMP9↓, PTEN↑, SHP1↑, eff↑, TumVol↓, TumW↓, *toxicity↓, *ROS↓,
7267- Gink,    Neuroprotective Potential of Biflavone Ginkgetin: A Review
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*neuroP↑, *ROS↓, *Aβ↓, *Inflam↓, *Dose↝, *cardioP↑, TumCCA↑, Apoptosis↑, TumAuto↑, STAT↓, *Stroke↓,
7256- Gink,    Neuroprotective effect of ginkgetin in experimental cerebral ischemia/reperfusion via apoptosis inhibition and PI3K/Akt/mTOR signaling pathway activation
- in-vivo, Stroke, NA
*Stroke↓, *Apoptosis↓, *Casp3↓, *BAX↓, *Bcl-2↑, *p‑Akt↑, *p‑mTOR↑,
7330- GSE,    Free radicals and grape seed proanthocyanidin extract: importance in human health and disease prevention
- Review, Var, NA
*BioAv↑, *ROS↓, AntiCan↑, selectivity↑, RenoP↑, *hepatoP↑, *DNAdam↓, *Stroke↓, *Bcl-2↑, cMyc↓,
7482- H2,    Molecular Hydrogen Therapy: Mechanisms, Delivery Methods, Preventive, and Therapeutic Application
- Review, Var, NA - Review, IBD, NA - Review, Stroke, NA - Review, Sepsis, NA - Review, AD, NA
Dose↝, *Inflam↓, *IL1β↓, *IL6↓, *TNF-α↓, *neuroP↑, *mTOR↓, *IL10↑, *TGF-β↑, *Sepsis↓, *NRF2↑, *antiOx↑, *Catalase↑, *SOD↑, *GPx↑, *ROS↓, *HO-1↑, *PI3K↑, *Akt↑, *hepatoP↑, *MPO↓, *cardioP↑, CDK4↓, CDK6↑, CD47↓, PI3K↓, Akt↓, Hif1a↓, selectivity↑, *MMP↑, *ATP↑, *ER Stress↓, *CHOP/DDIT3↓, *Casp12↓, *GRP78/BiP↓, *p38↓, *p‑JNK↓, *LC3‑Ⅱ/LC3‑Ⅰ↑, *p‑eIF2α↓, *ATF4↓, *XBP-1↓, *Imm↑, *IFN-γ↓, *IL4↓, *GranB/GZMB↓, NK cell↑, radioP↑, *CD4+↑, CD8+↑, *Dose↝, *other↑, *Dose↝, *antiPs↑, *BioAv↝, *GutMicro↑, Dose↝, *IBI↑, TumCP↓, TumCI↓, TumCMig↓, CD8+↑, PGC-1α↑, Akt↓, SCD1↓, *MDA↓, eff↑, *APP↓, *BACE↓, *Aβ↓, *cognitive↑, *neuroP↑, NP/CIPN↓, *Stroke↓, *NLRP3↓, *ALAT↓, *AST↓, *LPS↓, *hepatoP↑, chemoP↑, *creat↓, *Urea↓, *RenoP↑, *eff↑, Apoptosis↑, XIAP↓, IAP2/BIRC3↓, TumVol↓, MALAT1↓, EZH2↓, miR-124-3p↓, eff↑, ChemoSen↑, *compII↑, *compIII↑, *LDL↓, *Obesity↓, QoL↑, PFS↑,
7560- HYP,    Hyperoside: A Review of Its Structure, Synthesis, Pharmacology, Pharmacokinetics and Toxicity
- Review, Nor, NA - Review, AD, NA
*RenoP↓, Casp3↑, Casp8↑, MDA↑, GSH↓, SOD↓, Catalase↓, VEGF↓, Bcl-2↓, TumCG↓, p‑Akt↓, PI3K↓, TumCCA↑, TumCP↓, BMP7/OP1↓, *ZO-1↑, *BBB↝, *p‑Akt↑, *GSK‐3β↑, *SOD↑, *Catalase↑, *GSH↑, *SIRT1↑, *NF-kB↓, *IL1β↓, *IL6↓, *IL8↓, *TNF-α↓, *ROS↓, *MDA↓, *BAX↓, *Casp3↓, *Bcl-2↑, *BDNF↑, *TrkB↑, *NGF↑, *Apoptosis↓, *cardioP↑, *AST↓, *hepatoP↑, *AST↓, *ALAT↓, *MDA↓, *BACH1↓, *neuroP↑, *Stroke↓, *ICAM-1↓, *VCAM-1↓, *TLR4↓, *COX2/PTGS2↓, *RenoP↑, *NLRP3↓, *Casp1↓, *ASC↓, *BioAv↓, *BioAv↑, *toxicity↓,
7567- HYP,    Hyperoside: A review on its sources, biological activities, and molecular mechanisms
- Review, Var, NA
*AntiCan↑, *Bacteria↓, *AntiViral↑, *antiD↓, *RenoP↑, *hepatoP↑, *eff↑, *Sepsis↓, *AntiArt↑, *Stroke↓, TumCMig↓, TumCI↓, MTA1↓, TIMP2↓, MMP2↓, MMP↓, Cyt‑c↑, Akt↓, mTOR↓, P70S6K↓, TumAuto↑, PD-L1↓, TNF-α↓, IL1β↓, IL6↓, IL8↓, Bcl-2↓, Bcl-xL↓, BAX↑, BAD↑, Bak↑, VEGF↓, Casp3↑, Casp8↑, P53↑, GSH↓, SOD↓, Catalase↓, TAC↓, XIAP↓, ROS↓, NF-kB↓, TLR4↓, P-gp↓, LRP1↓, Fas↑, p27/CDKN1B↑, *cardioP↑, *AntiThr↑, *PAI-1/SERPINE1↓, *BUN↓, *ALAT↓, *AST↓, *neuroP?,
7495- MEL,    Melatonin: a promising neuroprotective agent for cerebral ischemia-reperfusion injury
- Review, Stroke, NA
*other↓, *neuroP↑, *Stroke↓, *Dose↝, *Risk↓, *cognitive↑,
6880- Phen,    Network Pharmacology of Natural Polyphenols for Stroke: A Bioinformatic Approach to Drug Design
- Study, Nor, NA
*neuroP↑, *other↝, *Stroke↓,

Showing Research Papers: 1 to 20 of 20

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 20

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

BMP7/OP1↓, 1,   CD47↓, 1,   miR-124-3p↓, 1,   MTA1↓, 1,   PFS↑, 1,   PLA2↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

Catalase↓, 2,   GSH↓, 2,   MDA↑, 1,   ROS↓, 1,   ROS↑, 1,   SOD↓, 2,   TAC↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

MMP↓, 1,   PGC-1α↑, 1,   XIAP↓, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

cMyc↓, 1,   SCD1↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 3,   p‑Akt↓, 1,   Apoptosis↑, 3,   BAD↑, 1,   Bak↑, 1,   BAX↑, 1,   Bcl-2↓, 3,   Bcl-xL↓, 2,   Casp↑, 1,   Casp3↑, 4,   Casp8↑, 2,   Casp9↑, 2,   Cyt‑c↑, 2,   Fas↑, 1,   IAP1↓, 1,   IAP2/BIRC3↓, 1,   iNOS↓, 1,   Mcl-1↓, 1,   p27/CDKN1B↑, 1,   survivin↓, 1,   TumCD↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

EZH2↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

TumAuto↑, 3,  

DNA Damage & Repair(tgid=10) ⓘ

P53↓, 1,   P53↑, 1,   PARP↑, 1,   cl‑PARP↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK4↓, 1,   cycD1/CCND1↓, 1,   mitA↑, 1,   TumCCA↑, 3,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ERK↓, 1,   GSK‐3β↑, 1,   HDAC1↓, 1,   mTOR↓, 1,   P70S6K↓, 1,   PI3K↓, 2,   PTEN↑, 1,   SHP1↑, 1,   STAT↓, 1,   STAT3↓, 2,   TumCG↓, 1,  

Migration(tgid=13) ⓘ

BACH1↓, 1,   LAMs↓, 1,   LRP1↓, 1,   MALAT1↓, 1,   MMP2↓, 3,   MMP9↓, 1,   TIMP2↓, 1,   TumCI↓, 2,   TumCMig↓, 2,   TumCP↓, 4,  

Angiogenesis & Vasculature(tgid=14) ⓘ

EGFR↓, 1,   Hif1a↓, 2,   VEGF↓, 3,  

Barriers & Transport(tgid=15) ⓘ

P-gp↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 3,   IL1β↓, 1,   IL6↓, 2,   IL8↓, 1,   JAK1↓, 1,   JAK2↓, 1,   M2 MC↓, 1,   NF-kB↓, 3,   NK cell↑, 1,   PD-1↓, 1,   PD-L1↓, 1,   PGE2↓, 1,   TLR4↓, 1,   TNF-α↓, 1,  

Protein Aggregation(tgid=19) ⓘ

NLRP3↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CDK6↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↝, 1,   ChemoSen↑, 3,   Dose↝, 3,   eff↑, 4,   selectivity↑, 2,  

Clinical Biomarkers(tgid=22) ⓘ

EGFR↓, 1,   EZH2↓, 1,   IL6↓, 2,   PD-L1↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 3,   AntiTum↑, 1,   chemoP↑, 1,   NP/CIPN↓, 2,   QoL↑, 1,   radioP↑, 1,   RenoP↑, 1,   Risk↓, 1,   TumVol↓, 2,   TumW↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,   CD8+↑, 2,  
Total Targets: 111

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

AntiArt↑, 1,   AntiBio↑, 2,   antiD↓, 1,   compII↑, 1,   PAF↑, 1,   Stroke↓, 20,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 1,   antiOx↑, 3,   Catalase↑, 3,   GPx↑, 2,   GSH↑, 3,   HO-1↓, 1,   HO-1↑, 2,   Keap1↓, 1,   Keap1↝, 1,   lipid-P↓, 1,   MDA↓, 5,   MPO↓, 2,   NRF2↓, 1,   NRF2↑, 4,   ROS↓, 9,   mt-ROS?, 1,   SOD↑, 2,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↓, 1,   ATP↑, 2,   compIII↑, 1,   Insulin↑, 1,   MMP↑, 2,   PGC-1α↝, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

AKT1↑, 1,   ALAT↓, 4,   BUN↓, 1,   glucose↓, 1,   LDL↓, 1,   SIRT1↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↑, 1,   p‑Akt↑, 2,   Apoptosis↓, 2,   BAX↓, 2,   Bcl-2↑, 3,   Casp1↓, 1,   Casp12↓, 1,   Casp3↓, 3,   GranB/GZMB↓, 1,   iNOS↓, 1,   p‑JNK↓, 1,   MAPK?, 1,   MAPK↓, 2,   p38↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   other?, 1,   other↓, 1,   other↑, 1,   other↝, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   p‑eIF2α↓, 1,   ER Stress↓, 1,   GRP78/BiP↓, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3II↑, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,   PARP1↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

TumCCA↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

GSK‐3β↑, 1,   mTOR↓, 1,   p‑mTOR↑, 1,   PI3K↓, 1,   PI3K↑, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   APP↓, 1,   BACH1↓, 1,   PAI-1/SERPINE1↓, 1,   TGF-β↑, 1,   TIMP1↓, 1,   VCAM-1↓, 2,   ZO-1↑, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↑, 1,   ATF4↓, 1,   NO↓, 2,   VEGF↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↝, 1,   IBI↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

ASC↓, 1,   CD4+↑, 1,   COX2/PTGS2↓, 2,   COX2/PTGS2↑, 1,   ICAM-1↓, 2,   IFN-γ↓, 2,   IL10↑, 1,   IL18↓, 1,   IL1β↓, 5,   IL4↓, 1,   IL6↓, 5,   IL8↓, 1,   Imm↑, 1,   Inflam↓, 9,   LPS↓, 1,   pol-M2 MC↑, 1,   MCP1/CCL2↓, 2,   MIP2↓, 1,   NF-kB↓, 5,   PGE2↓, 2,   RANTES↓, 1,   TLR4↓, 1,   TNF-α↓, 5,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,   AChE↓, 2,   BDNF↑, 2,   BrainVol↑, 1,   NGF↑, 2,   p‑tau↓, 1,   TrkB↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 3,   BACE↓, 1,   NLRP3↓, 2,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2,   BioAv↑, 4,   BioAv↝, 1,   Dose↑, 1,   Dose↝, 7,   eff↑, 4,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 4,   AST↓, 5,   BloodF↑, 1,   BMD↑, 1,   creat↓, 1,   GutMicro↑, 2,   IL6↓, 5,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 2,   AntiDiabetic↑, 3,   antiPs↑, 2,   cardioP↑, 6,   chemoP↑, 1,   cognitive↑, 5,   hepatoP↑, 6,   memory↑, 2,   neuroP?, 1,   neuroP↑, 14,   Obesity↓, 3,   RenoP↓, 1,   RenoP↑, 3,   Risk↓, 1,   toxicity↓, 7,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↓, 1,   AntiFungal↑, 1,   AntiViral↑, 3,   Bacteria↓, 4,   Sepsis↓, 3,  
Total Targets: 152

Scientific Paper Hit Count for: Stroke, Stroke
4 Ginkgetin
3 Ginkgo biloba-EGb 761
2 Ginkgo biloba
2 Hyperoside
1 flavonoids
1 Formononetin
1 Gallic acid
1 Ginkgolide B
1 Ginger/6-Shogaol/Gingerol
1 Grapeseed extract
1 Hydrogen Gas
1 Melatonin
1 Phenolic Acids
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:1534  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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