anemia Cancer Research Results

anemia, anemia: Click to Expand ⟱
Source:
Type:

Anemia

Type: Clinical phenotype / hematologic outcome

Function: Anemia is a reduction in the oxygen-carrying capacity of blood, typically reflected by decreased hemoglobin concentration, hematocrit, and/or red blood cell count. It can result from impaired erythropoiesis, nutritional deficiency, chronic inflammation, blood loss, hemolysis, bone marrow suppression, renal dysfunction, or treatment toxicity.

Cancer: ↑ Anemia is common in cancer and may result from the malignancy itself, chronic inflammation, nutritional deficiency, marrow infiltration, renal dysfunction, bleeding, chemotherapy, or radiotherapy. Increased anemia is associated with fatigue, reduced functional status, treatment intolerance, and in some settings poorer prognosis.

Favorable Direction: ↓ Anemia is favorable. When measured using laboratory variables, ↑ hemoglobin, ↑ hematocrit, and restoration of red blood cell count toward the normal range generally indicate improvement.

***"Most studies have shown similar or superior efficacy of bLF to traditionally used therapy (ferrous sulfate and ferric hydroxide) in restoring iron deficiency, with significantly fewer gastrointestinal side effects"
Scientific Papers found: Click to Expand⟱
7125- Ge-132,    A review of public and environmental consequences of organic germanium
- Review, Nor, NA
*toxicity↓, other↝, Imm↑, anemia↓,
8135- LF,    Lactoferrin-A Regulator of Iron Homeostasis and Its Implications in Cancer
- Review, Var, NA - Review, AD, NA
IronCh↑, ROS↓, Imm↑, Inflam↓, *BBB↑, Iron↝, *Fenton↓, *ROS↓, *TAC↑, *SOD↑, *GPx↑, *GSH↑, *TBARS↓, *PTEN↓, *tau↓, *MAPK↓, *Aβ42↓, *Apoptosis↓, *Casp3↓, *Akt↑, *GutMicro↑, *Sepsis↓, *anemia↓, *IL6↓, *FPN↑, *TfR1/CD71↑, *Ferritin↓, *HemoG↑, *RBC↑, *eff↑, *BioAv↓, *BioAv↑, *BioAv↝, *ChemoSen↑, *BioAv↑, Ferroptosis↑,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

anemia↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

Ferroptosis↑, 1,   Iron↝, 1,   ROS↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Cell Death(tgid=5) ⓘ

Ferroptosis↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

other↝, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Imm↑, 2,   Inflam↓, 1,  
Total Targets: 9

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

anemia↓, 1,   Aβ42↓, 1,   FPN↑, 1,   RBC↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

Fenton↓, 1,   GPx↑, 1,   GSH↑, 1,   ROS↓, 1,   SOD↑, 1,   TAC↑, 1,   TBARS↓, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   TfR1/CD71↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↑, 1,   Apoptosis↓, 1,   Casp3↓, 1,   MAPK↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

PTEN↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

IL6↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

tau↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 2,   BioAv↝, 1,   ChemoSen↑, 1,   eff↑, 1,  

Clinical Biomarkers(tgid=22) ⓘ

Ferritin↓, 1,   GutMicro↑, 1,   HemoG↑, 1,   IL6↓, 1,  

Functional Outcomes(tgid=23) ⓘ

toxicity↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

Sepsis↓, 1,  
Total Targets: 32

Scientific Paper Hit Count for: anemia, anemia
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:1582  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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