APG Cancer Research Results

APG, Adenomatous Polyp Growth: Click to Expand ⟱
Source:
Type:

Adenomatous Polyp Growth

Alternative Names: Colorectal adenoma growth, adenoma burden, intestinal adenomatous polyp development

Type: Precancerous lesion / disease-progression phenotype / tumorigenesis outcome

Function: Adenomatous polyps are premalignant epithelial lesions of the colon and rectum that can accumulate additional genetic and epigenetic alterations and progress toward colorectal carcinoma. Experimental studies commonly assess adenoma number, size, volume, multiplicity, or overall tumor burden as measures of intestinal tumorigenesis.

Cancer: ↑ Increased adenomatous polyp formation or growth is unfavorable and reflects increased colorectal tumor initiation and/or progression. Adenomas are established precursor lesions in the adenoma-carcinoma sequence, although not every adenoma progresses to invasive cancer.

Favorable Direction in Cancer Prevention: ↓ Reduced adenoma formation, number, size, growth, or total polyp burden is favorable and indicates suppression of precancerous colorectal tumorigenesis.
Scientific Papers found: Click to Expand⟱
8123- LF,    Effect of orally administered bovine lactoferrin on the growth of adenomatous colorectal polyps in a randomized, placebo-controlled clinical trial
- Trial, CRC, NA
AntiCan↑, Dose↝, APG↓,
8124- LF,    Inhibition of intestinal polyp growth by oral ingestion of bovine lactoferrin and immune cells in the large intestine
- Trial, CRC, NA
Risk↓, Dose↝, NK cell↑, Neut↑, CD4+↑, Imm↑, APG↓,

Showing Research Papers: 1 to 2 of 2

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 2

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

APG↓, 2,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   Imm↑, 1,   Neut↑, 1,   NK cell↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose↝, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   Risk↓, 1,  
Total Targets: 8

Pathway results for Effect on Normal Cells:


Total Targets: 0

Scientific Paper Hit Count for: APG, Adenomatous Polyp Growth
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:1764  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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