CRP Cancer Research Results

CRP, C-reactive protein: Click to Expand ⟱
Source:
Type:
C-Reactive Protein (CRP) is a protein produced by the liver in response to inflammation in the body.
C-reactive protein is an acute-phase reactant synthesized by the liver in response to IL-6–driven inflammation.

In oncology, it serves as a host-response biomarker, not a tumor marker.

An elevated CRP integrates multiple cancer-relevant processes:
-Tumor-associated inflammation and necrosis
-Cytokine signaling (especially IL-6)
-Infection or treatment-related tissue injury
-Cachexia and systemic catabolism

Because it aggregates these signals, CRP is a powerful global severity indicator.

Prognosis (Primary Use)
-Higher baseline CRP correlates with shorter overall survival across many cancers.
-Rising CRP often precedes clinical decline.

Treatment Tolerance & Risk
-Elevated CRP predicts poor chemotherapy tolerance, higher complication rates, and inferior immunotherapy outcomes in several settings.


Scientific Papers found: Click to Expand⟱
3972- ACNs,    Recent Research on the Health Benefits of Blueberries and Their Anthocyanins
- Review, AD, NA - Review, Park, NA
*cardioP↑, *neuroP↑, *Inflam↓, *antiOx↓, *GutMicro↑, *Half-Life↑, *LDL↓, *adiP↓, *HDL↑, *CRP↓, *IL1β↓, *Risk↓, *Risk↓, *cognitive↑, *memory↑, *other↑, *BOLD↑, *NO↓, *MDA↓, *GSH↑, *VitC↑, *SOD↑, *GPx↑, *eff↓, *eff↓, *eff↓, *eff↝, *Risk↓,
7407- Amla,    Functional and Nutraceutical Significance of Amla (Phyllanthus emblica L.): A Review
- Review, Nor, NA
*Inflam↓, *antiOx↑, *GSH↑, *GPx↑, *SOD↑, *Catalase↑, *lipid-P↓, *ROS↓, *cardioP↑, *AntiDiabetic↑, *neuroP↑, *GastroP↑, *COX2/PTGS2↓, *MDA↓, *BAX↓, *TG/TAG↓, *HDL↑, *LDL↓, *HMG-CoA↓, *Dose↝, *CRP↓, DNAdam↑, Casp3↑, Casp7↑, Casp8↑, Fas↑, TumCI↓, selectivity↑,
7401- Amla,    The impact of Emblica Officinalis (Amla) on lipid profile, glucose, and C-reactive protein: A systematic review and meta-analysis of randomized controlled trials
- Review, Nor, NA
*CRP↓, *glucose↓, *LDL↓, Dose↑,
3676- Ash,    Effect of Withania somnifera (Ashwagandha) root extract on amelioration of oxidative stress and autoantibodies production in collagen-induced arthritic rats
- in-vivo, Arthritis, NA
*CRP↓, *ROS↓, *lipid-P↓, *GSTs↓, *GSH↑, *antiOx↑, *Inflam↓,
4274- BBR,    Berberine exerts antidepressant effects in vivo and in vitro through the PI3K/AKT/CREB/BDNF signaling pathway
- in-vivo, AD, NA
*IL1β↓, *IL6↓, *TNF-α↓, *CRP↓, *CREB↑, *BDNF↑,
4625- Bor,    Boron and Inflammation
- Review, Arthritis, NA - Review, ostP, NA
*Risk↓, *eff↑, *SOD↑, *NF-kB↓, *Risk↓, *CRP↓, *TNF-α↓, *Wound Healing↑,
2775- Bos,    The journey of boswellic acids from synthesis to pharmacological activities
- Review, Var, NA - Review, AD, NA - Review, PSA, NA
ROS↑, ER Stress↑, TumCG↓, Apoptosis↑, Inflam↓, ChemoSen↑, Casp↑, ERK↓, cl‑PARP↑, AR↓, cycD1/CCND1↓, VEGFR2/KDR/Flk1↓, CXCR4↓, radioP↑, NF-kB↓, VEGF↓, P21↑, Wnt↓, β-catenin/ZEB1↓, Cyt‑c↑, MMP2↓, MMP1↓, MMP9↓, PI3K↓, MAPK↓, JNK↑, *5LO↓, *NRF2↑, *HO-1↑, *MDA↓, *SOD↑, *hepatoP↑, *ALAT↓, *AST↓, *LDH↑, *CRP↓, *COX2/PTGS2↓, *GSH↑, *ROS↓, *Imm↑, *Dose↝, *eff↑, *neuroP↑, *cognitive↑, *IL6↓, *TNF-α↓, *AntiArt↑, *AntiDiabetic↑, *antiAll↑,
5926- CAR,    An Updated Review of Research into Carvacrol and Its Biological Activities
- Review, Nor, NA - Review, AD, NA - Review, Asthma, NA
*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↑, *toxicity↓, *Pain↓, *TRPV3↑, *NRF2↑, *Ca+2↑, *ATP↑, *5LO↓, *COX2/PTGS2↓, PGE2↓, *hepatoP↑, *AntiAg↑, *Diar↓, *cardioP↑, *other↝, *chemoPv↑, *cognitive↑, *AChE↓, *GastroP↑, *Synergy↑, *BChE↓, *CRP↓, *antiAll↑,
9138- CC,    Tropical fruit camu-camu (Myrciaria dubia) has anti-oxidative and anti-inflammatory properties
- Study, Nor, NA
*Ingr↝, *Dose?, *8-oxo-dG↓, *ROS↓, *Inflam↓, *CRP↓, *IL6?, *IL8?, *eff↑, *antiOx↑,
5943- Cela,    Celastrol: A Spectrum of Treatment Opportunities in Chronic Diseases
- Review, Arthritis, NA - Review, IBD, NA - Review, AD, NA - Review, Park, NA
*other↝, *other↝, *CRP↓, *eff↝, *other↑, *CXCR4↓, *IL1β↓, *IL6↓, *IL17↓, *IL18↓, *TNF-α↓, *MMP9↓, *PGE2↓, *COX1↓, *COX2/PTGS2↓, *PI3K↓, *Akt↓, *other↑, TumCCA↑, Apoptosis↑, ROS↑, JNK↑, TumAuto↑, Hif1a↓, BNIP3↝, HSP90↓, Fas↑, FasL↑, ETC↓, VEGF↓, angioG↓, RadioS↑, *neuroP↑, *HSP70/HSPA5↑, *ROS↓, *MMP↑, *Cyt‑c↓, *Casp3↓, *Casp9↓, *MAPK↓, *Dose⇅, *HSPs↑, BioAv↓, Dose↝,
6216- CUR,    Role of Turmeric and Curcumin in Prevention and Treatment of Chronic Diseases: Lessons Learned from Clinical Trials
- Review, Var, NA
TumCG↓, angioG↓, EMT↓, TumCI↓, TumMeta↓, *GutMicro↑, *BioAv↓, *HO-1↑, *ROS↓, *COX2/PTGS2↓, *iNOS↓, PKCδ↓, EGFR↓, NF-kB↓, cJun↓, cFos↓, cMyc↓, Akt↓, PI3K↓, CDK4↓, *TNF-α↓, *CRP↓, *IL6↓, MMP9↓, VEGF↓, JAK↓, STAT↓, IL1↓, IL2↓, IL6↓, IL8↓, IL12↓, MCP1/CCL2↓, Apoptosis↑, ER Stress↑, 5LO↓, XO↓, *NRF2↑, *HO-1↑, *AChE↓, *neuroP↑, *glucose↓, *GLUT2↑, *GLUT3↑, *GLUT4↑, *GlucoseCon↑, *AMPK↑, *BMD↑, *MDA↓, *Synergy↑, Synergy↑, P53↑, BAX↑, DNAdam↑, Bcl-2↓, CSCs↓, ALDH↓, CD133↑,
9037- CV,  SP,    Chlorella and Arthrospira (Spirulina) as Multi-Pathway Biological Response Modulators: Molecular Mechanisms, Signaling Pathways and Clinical Evidence
- Review, Nor, NA
*NRF2↑, *NF-kB↓, *antiOx↑, *BP↝, *GutMicro↑, *Ingr?, *Synergy↑, *antiOx↑, *ROS↓, *toxicity↝, *MMP↑, *ATP↑, *MitoP↑, *lipid-P↓, *MDA↓, *SOD↑, *GPx↑, *TAC↑, *NK cell↑, *IFN-γ↑, *CRP↓, *SCFAs↑, *TC↓, *LDL↓, *TG/TAG↓, *toxicity↝, AntiTum↑, Ki-67↓, ER-α36↓, P53↑, P21↑, TumCCA↑, Bax:Bcl2↑, Apoptosis↑, Synergy↑,
6716- dietF,    Current Research in Fermented Foods: Bridging Tradition and Science
- Review, Nor, NA
*GutMicro↑, *Inflam↓, *BP↓, *LDL↓, *HDL↑, *CRP↓, *IL6↓, *TNF-α↓, *Obesity↓, *AntiDiabetic↑, *cardioP↑, *GutMicro↑, *neuroP↑, *cognitive↑,
5069- dietSTF,    The Role of Intermittent Fasting in the Activation of Autophagy Processes in the Context of Cancer Diseases
- Review, Var, NA
Risk↓, ChemoSen↑, RadioS↑, *Dose↝, *Dose↝, *Dose↝, *LDL↓, *CRP↓, *TNF-α↓, TumAuto↓, GLUT1↓, GLUT2↓, glucose↓, IGF-1↓, Insulin↓, mTOR↓, mTORC1↓, AMPK↑, Warburg↓, OXPHOS↑, ROS↑, DNAdam↑, JAK1↓, STAT↓, TumCP↓, QoL↑,
6803- EA,    Effects of Ellagic Acid on Oxidative Stress Index, Inflammatory Markers and Quality of Life in Patients With Irritable Bowel Syndrome: Randomized Double-blind Clinical Trial
- Trial, IBD, NA
*Dose↝, *MDA↓, *TAC↑, *CRP↓, *IL6↓, *Inflam↓, *ROS↓, *QoL↑, *toxicity↓,
6574- EU,    Effects of Eurycoma longifolia Jack on chronic cerebral hypoperfusion-induced oxidative damage and memory deficit in rats
- in-vivo, Nor, NA
*cognitive↑, *antiOx↓, *MDA↓, *CRP↓, *neuroP↑, *Inflam↓,
8584- FS,    Anti-Oxidant and Anti-Cancer Properties of Flaxseed
- Review, Nor, NA
*Ingr↝, *cardioP↑, *LDL↓, *lipidLev↓, *AntiDiabetic↑, *hepatoP↑, *AntiCan↑, *Analgesic↑, *AntiArt↑, *CRP↓, *TNF-α↓, *Inflam↓, *toxicity↝, *neuroP↑, *Ingr↝, *Ingr↝, *AntiViral↑, Risk↓, *Ingr↝, *hs-CRP↓, *GutMicro↑, *TJ↑, *OCLN↝, *MLC2/MYL9↝, *VCAM-1↓, *Akt2↓, *IKKα↓, *NF-kB↓, Synergy↑, HER2/EBBR2↓, MAPK↓, PI3K↓, Akt↓, EGFR↓, TumCG↓, TumMeta↓, IGF-1↓, COX2/PTGS2↓, PGE2↓, CDK4↓, TNF-α↓, IL1β↓, lipid-P↑, P53↑, MDM2↑, cl‑Casp3↑, cl‑PARP↑, cl‑Casp7↑, BAX↑, Bcl-2↓, Bax:Bcl2↑, Cyt‑c↑, Casp9↑, Ki-67↓, CYP1A1↑, p38↑, ERK↑, Synergy↑, ChemoSen↑, *BioAv↑, eff↝, Ingr↝,
8585- FS,    Dietary flaxseed: Cardiometabolic benefits and its role in promoting healthy aging
- Review, Nor, NA
*cardioP↑, *Obesity↓, *lipidLev↓, *BP↓, *Inflam↓, *CRP↓, *IL6↓, *ROS↓, *hepatoP↑, *Ingr↝, *GutMicro↑, *Dose↑, *Ingr↝, *Ingr?, *CompStab↝, *MDA↓, *hs-CRP↓, *TNF-α↓, *AntiDiabetic↑, *ALAT↓, *AST↓, *GGT/CD224↓, *TG/TAG↓, *LDL↓, *HDL∅, *TC↓, *glucose↓, *Insulin↓, *SIRT1↑, *Dose↝, *Dose?,
8603- FSO,    Flaxseed oil supplementation decreases C-reactive protein levels in chronic hemodialysis patients
- Trial, Nor, NA
*Dose↝, *CRP↓,
8468- Mg,    The effect of long-term magnesium intake on inflammatory markers in patients with metabolic syndrome: a systematic review and meta-analysis of randomized controlled trials
- Trial, Obesity, NA
*CRP↓,
8469- Mg,    Unlocking the Power of Magnesium: A Systematic Review and Meta-Analysis Regarding Its Role in Oxidative Stress and Inflammation
- Review, Nor, NA
*CRP↓, *ROS∅, *Inflam↓,
8470- Mg,  Z,    The Effects of Magnesium and Zinc Co-Supplementation on Biomarkers of Inflammation and Oxidative Stress, and Gene Expression Related to Inflammation in Polycystic Ovary Syndrome: a Randomized Controlled Clinical Trial
- Trial, Nor, NA
*Dose?, *CRP↓, *PCO↓, *TAC↑, *IL1↓, *TNF-α↓,
8475- Mg,    Magnesium supplementation improves indicators of low magnesium status and inflammatory stress in adults older than 51 years with poor quality sleep
- Trial, Nor, NA
*Dose↝, *Obesity↓, *CRP↓,
3347- QC,    Recent Advances in Potential Health Benefits of Quercetin
- Review, Var, NA - Review, AD, NA
*antiOx↑, *ROS↓, *Inflam↓, TumCP↓, Apoptosis↑, *cardioP↑, *BP↓, TumMeta↓, MDR1↓, NADPH↓, ChemoSen↑, MMPs↓, TIMP2↑, *NLRP3↓, *IFN-γ↑, *COX2/PTGS2↓, *NF-kB↓, *MAPK↓, *CRP↓, *IL6↓, *TNF-α↓, *IL1β↓, *TLR4↑, *PKCδ↓, *AP-1↓, *ICAM-1↓, *NRF2↑, *HO-1↑, *lipid-P↓, *neuroP↑, *Synergy↑, *memory↑, *cognitive↑, *AChE↓, *BioAv↑, *BioAv↑, *BioAv↑, *BioAv↑, *BioAv↑,
4603- SeNPs,    Therapeutic applications of selenium nanoparticles
- Review, Var, NA
AntiCan↑, Imm↑, *AntiDiabetic↑, *antiOx↑, *Inflam↓, ROS↑, ER Stress↑, DNAdam↑, *toxicity↓, *eff↑, *BioAv↑, selectivity↑, TumCCA↑, Risk↓, *lipid-P↓, *TNF-α↓, *CRP↓, TumMeta↓, angioG↓, selectivity↑, Synergy↑, *Synergy↑,
4601- SeNPs,  AgNPs,    Antioxidant and hepatoprotective role of selenium against silver nanoparticles
- in-vivo, Nor, NA
*TAC↑, *CRP↓, *AST↓, *ALAT↓, *toxicity↓, *GSH↑, *SOD↑, *Catalase↑, *hepatoP↑,
4498- SSE,    Selenium in Human Health and Gut Microflora: Bioavailability of Selenocompounds and Relationship With Diseases
- Review, Var, NA - Review, AD, NA - Review, IBD, NA
*Imm↑, *GutMicro↑, *BioAv↑, *Risk↓, *Dose↝, Risk↓, *CRP↓, *GPx↓, *Inflam↓, *selenoP↑, *Dose↝, *ROS↓, *MDA↓, *SOD↑, *GPx↑, *IL1↓, *MCP1/CCL2↓, *IL6↓, *TNF-α↓, Risk↓, *neuroP↑, *memory↑,
4494- SSE,    Advances in the study of selenium and human intestinal bacteria
- Review, IBD, NA - Review, Var, NA
*Risk↓, OS↑, *CRP↓, *GPx↑, *Inflam↓, *ROS↓, *GutMicro↑, *selenoP↑, *other↓,
3960- Taur,    Versatile Triad Alliance: Bile Acid, Taurine and Microbiota
- Review, AD, NA - Review, Stroke, NA
*ROS↓, *Inflam↓, *GABA↑, *memory↑, *cognitive↑, *iNOS↓, *CRP↓, *HO-1↑, *Prx↑, *Trx↑, *NRF2↑, *GSH↑, *SOD↑, *Catalase↑, *lipid-P↓, *MDA↓, *eff↝, *GutMicro↑, other↑,
3409- TQ,    Thymoquinone therapy remediates elevated brain tissue inflammatory mediators induced by chronic administration of food preservatives
- in-vivo, Nor, NA
*MDA↓, *TGF-β↓, *CRP↓, *NF-kB↓, *TNF-α↓, *IL1β↓, *Casp3↓, *GSH↑, *NRF2↑, *IL10↑, *neuroP↑, *ROS↓, *Apoptosis↓, *Inflam↓,
3422- TQ,    Thymoquinone, as a Novel Therapeutic Candidate of Cancers
- Review, Var, NA
selectivity↑, P53↑, PTEN↑, NF-kB↓, PPARγ↓, cMyc↓, Casp↑, *BioAv↓, CompStab↝, Synergy↑, survivin↓, Bcl-xL↓, Bcl-2↓, Akt↓, BAX↑, cl‑PARP↑, CXCR4↓, MMP9↓, VEGFR2/KDR/Flk1↓, Ki-67↓, COX2/PTGS2↓, JAK2↓, cSrc↓, Apoptosis↑, p‑STAT3↓, cycD1/CCND1↓, Casp3↑, Casp7↑, Casp9↑, N-cadherin↓, Vim↓, Twist↓, E-cadherin↑, ChemoSen↑, Synergy↑, EMT↓, ROS↑, DNMT1↓, Synergy↑, EZH2↓, hepatoP↑, Zeb1↓, RadioS↑, HDAC↓, HDAC1↓, HDAC2↓, HDAC3↓, *NAD↑, *SIRT1↑, SIRT1↓, *Inflam↓, *CRP↓, *TNF-α↓, *IL6↓, *IL1β↓, *Synergy↑, *MDA↓, *NO↓, *GSH↑, *SOD↑, *Catalase↑, *GPx↑, PI3K↓, mTOR↓,
3559- TQ,    Molecular signaling pathway targeted therapeutic potential of thymoquinone in Alzheimer’s disease
- Review, AD, NA - Review, Var, NA
*antiOx↑, *Inflam↓, *AChE↓, AntiCan↑, *cardioP↑, *RenoP↑, *neuroP↑, *hepatoP↑, TumCG↓, Apoptosis↑, PI3K↓, Akt↑, TumCCA↑, angioG↓, *NF-kB↓, *TLR2↓, *TLR4↓, *MyD88↓, *TRIF↓, *IRF3↓, *IL1β↓, *IL6↓, *IL12↓, *NRF2↑, *COX2/PTGS2↓, *VEGF↓, *MMP9↓, *cMyc↓, *cycD1/CCND1↓, *TumCP↓, *TumCI↓, *MDA↓, *TGF-β↓, *CRP↓, *Casp3↓, *GSH↑, *IL10↑, *iNOS↑, *lipid-P↓, *SOD↑, *H2O2↓, *ROS↓, *LDH↓, *Catalase↑, *GPx↑, *AChE↓, *cognitive↑, *MAPK↑, *JNK↑, *BAX↓, *memory↑, *Aβ↓, *MMP↑,
4869- Uro,    Urolithin A in Central Nervous System Disorders: Therapeutic Applications and Challenges
- Review, AD, NA - Review, Park, NA - Review, Stroke, NA
*MitoP↑, *Inflam↓, *antiOx↑, *Risk↓, *Aβ↓, *p‑tau↓, *p62↓, *PARK2↑, *MMP↑, *ROS↓, *Strength↑, *CRP↓, *IL1β↓, *IL6↓, *TNF-α↓, *AMPK↑, *NF-kB↓, *MAPK↓, *p62↑, *NRF2↑, *SOD↑, *Catalase↑, *HO-1↑, *Ferroptosis↓, *lipid-P↓, *Cartilage↑, *PI3K↓, *Akt↓, *mTOR↓, *Apoptosis↓, *neuroP↑, *Bcl-2↓, *BAX↑, *Casp3↑, *ATP↑, *Synergy↑, *motorD↑, *NLRP3↓, *radioP↑, *BBB↑,
3112- VitC,    Antioxidative and Anti-Inflammatory Activity of Ascorbic Acid
- Review, Nor, NA
*ROS↓, *antiOx↑, *SOD↑, *Catalase↑, *GPx↑, *NRF2↑, *AP-1↑, *Inflam↓, *CRP↓, IFN-γ↓,

Showing Research Papers: 1 to 34 of 34

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 34

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

lipid-P↑, 1,   ROS↑, 5,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

ETC↓, 1,   Insulin↓, 1,   OXPHOS↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 1,   AMPK↑, 1,   glucose↓, 1,   NADPH↓, 1,   SIRT1↓, 1,   Warburg↓, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 7,   BAX↑, 3,   Bax:Bcl2↑, 2,   Bcl-2↓, 3,   Bcl-xL↓, 1,   BNIP3↝, 1,   Casp↑, 2,   Casp3↑, 2,   cl‑Casp3↑, 1,   Casp7↑, 2,   cl‑Casp7↑, 1,   Casp8↑, 1,   Casp9↑, 2,   Cyt‑c↑, 2,   Fas↑, 2,   FasL↑, 1,   MDM2↑, 1,   p38↑, 1,   survivin↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 3,   Akt↑, 1,   cSrc↓, 1,   EGFR↓, 2,   ERK↓, 1,   ERK↑, 1,   HER2/EBBR2↓, 1,   JAK↓, 1,   JAK1↓, 1,   JAK2↓, 1,   JNK↑, 2,   MAPK↓, 2,   mTOR↓, 2,   PI3K↓, 5,   PKCδ↓, 1,   PTEN↑, 1,   STAT↓, 2,   p‑STAT3↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

cJun↓, 1,   cMyc↓, 2,   DNMT1↓, 1,   EZH2↓, 1,   HDAC↓, 1,   HDAC1↓, 1,   HDAC2↓, 1,   HDAC3↓, 1,   other↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↑, 3,   HSP90↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

TumAuto↓, 1,   TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 4,   P53↑, 4,   cl‑PARP↑, 3,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK4↓, 2,   cycD1/CCND1↓, 2,   Ki-67↓, 3,   P21↑, 2,   TumCCA↑, 4,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

ALDH↓, 1,   CD133↑, 1,   cFos↓, 1,   CSCs↓, 1,   IGF-1↓, 2,   Ki-67↓, 3,   mTORC1↓, 1,   TumCG↓, 4,   TumCP↓, 2,   Wnt↓, 1,  

Migration(tgid=13) ⓘ

E-cadherin↑, 1,   EMT↓, 2,   MMP1↓, 1,   MMP2↓, 1,   MMP9↓, 3,   MMPs↓, 1,   N-cadherin↓, 1,   TIMP2↑, 1,   TumCI↓, 2,   TumMeta↓, 4,   Twist↓, 1,   Vim↓, 1,   Zeb1↓, 1,   β-catenin/ZEB1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 4,   Hif1a↓, 1,   VEGF↓, 3,   VEGFR2/KDR/Flk1↓, 2,  

Barriers & Transport(tgid=15) ⓘ

GLUT1↓, 1,   GLUT2↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 2,   CXCR4↓, 2,   IFN-γ↓, 1,   IL1↓, 1,   IL12↓, 1,   IL1β↓, 1,   IL2↓, 1,   IL6↓, 1,   IL8↓, 1,   Imm↑, 1,   Inflam↓, 1,   MCP1/CCL2↓, 1,   NF-kB↓, 3,   PGE2↓, 2,   TNF-α↓, 1,  

Protein Aggregation(tgid=19) ⓘ

XO↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 1,   ER-α36↓, 1,   PPARγ↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   ChemoSen↑, 5,   CompStab↝, 1,   CYP1A1↑, 1,   Dose↑, 1,   Dose↝, 1,   eff↝, 1,   MDR1↓, 1,   RadioS↑, 3,   selectivity↑, 4,   Synergy↑, 8,  

Clinical Biomarkers(tgid=22) ⓘ

AR↓, 1,   EGFR↓, 2,   EZH2↓, 1,   HER2/EBBR2↓, 1,   IL6↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 2,   AntiTum↑, 1,   hepatoP↑, 1,   OS↑, 1,   QoL↑, 1,   radioP↑, 1,   Risk↓, 5,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr↝, 1,  
Total Targets: 142

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 2,   antiOx↑, 11,   Catalase↑, 7,   GPx↓, 1,   GPx↑, 8,   GSH↑, 9,   GSTs↓, 1,   H2O2↓, 1,   HDL↑, 3,   HDL∅, 1,   HO-1↑, 6,   lipid-P↓, 8,   MDA↓, 13,   NRF2↑, 10,   PCO↓, 1,   Prx↑, 1,   ROS↓, 17,   ROS∅, 1,   selenoP↑, 2,   SOD↑, 12,   TAC↑, 4,   Trx↑, 1,   VitC↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

Insulin↓, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 2,   adiP↓, 1,   ALAT↓, 3,   AMPK↑, 2,   ATP↑, 3,   glucose↓, 3,   GlucoseCon↑, 1,   HMG-CoA↓, 1,   LDL↓, 8,   lipidLev↓, 2,   NAD↑, 1,   SCFAs↑, 1,   SIRT1↑, 2,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 2,   BAX↓, 2,   BAX↑, 1,   Bcl-2↓, 1,   Casp3↓, 3,   Casp3↑, 1,   Casp9↓, 1,   Cyt‑c↓, 1,   Ferroptosis↓, 1,   iNOS↓, 2,   iNOS↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 2,   Akt2↓, 1,   CREB↑, 1,   IKKα↓, 1,   JNK↑, 1,   MAPK↓, 3,   MAPK↑, 1,   mTOR↓, 1,   PI3K↓, 2,   PKCδ↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

cMyc↓, 1,   other↓, 1,   other↑, 3,   other↝, 3,  

Protein Folding & ER Stress(tgid=8) ⓘ

HSP70/HSPA5↑, 1,   HSPs↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

MitoP↑, 2,   p62↓, 1,   p62↑, 1,   PARK2↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

8-oxo-dG↓, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

TumCP↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↑, 1,   AP-1↓, 1,   AP-1↑, 1,   Ca+2↑, 1,   Cartilage↑, 1,   MLC2/MYL9↝, 1,   MMP9↓, 2,   TGF-β↓, 2,   TumCI↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

NO↓, 2,   VCAM-1↓, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   GastroP↑, 2,   GLUT2↑, 1,   GLUT3↑, 1,   GLUT4↑, 1,   MMP↑, 4,   OCLN↝, 1,   TJ↑, 1,   TRPV3↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX1↓, 1,   COX2/PTGS2↓, 7,   CXCR4↓, 1,   ICAM-1↓, 1,   IFN-γ↑, 2,   IL1↓, 2,   IL10↑, 2,   IL12↓, 1,   IL17↓, 1,   IL18↓, 1,   IL1β↓, 8,   IL6?, 1,   IL6↓, 12,   IL8?, 1,   Imm↑, 2,   Inflam↓, 21,   IRF3↓, 1,   MCP1/CCL2↓, 1,   MyD88↓, 1,   NF-kB↓, 7,   NK cell↑, 1,   NLRP3↓, 2,   PGE2↓, 1,   TLR2↓, 1,   TLR4↓, 1,   TLR4↑, 1,   TNF-α↓, 16,   TRIF↓, 1,  

Cellular Microenvironment(tgid=17) ⓘ

GGT/CD224↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 5,   BChE↓, 1,   BDNF↑, 1,   GABA↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 2,   p‑tau↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 2,   BioAv↑, 9,   CompStab↝, 1,   Dose?, 3,   Dose↑, 1,   Dose⇅, 1,   Dose↝, 11,   eff↓, 3,   eff↑, 4,   eff↝, 3,   Half-Life↑, 1,   Synergy↑, 7,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 3,   AST↓, 3,   BMD↑, 1,   BP↓, 3,   BP↝, 1,   CRP↓, 34,   hs-CRP↓, 2,   IL6?, 1,   IL6↓, 12,   LDH↓, 1,   LDH↑, 1,   TC↓, 2,   TG/TAG↓, 3,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 1,   antiAll↑, 2,   AntiArt↑, 2,   AntiCan↑, 1,   AntiDiabetic↑, 6,   BOLD↑, 1,   cardioP↑, 8,   chemoPv↑, 1,   cognitive↑, 8,   hepatoP↑, 6,   memory↑, 5,   motorD↑, 1,   neuroP↑, 14,   Obesity↓, 3,   Pain↓, 1,   QoL↑, 1,   radioP↑, 1,   RenoP↑, 1,   Risk↓, 8,   Strength↑, 1,   toxicity↓, 4,   toxicity↝, 3,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiViral↑, 1,   Diar↓, 1,   GutMicro↑, 10,  

Ingredients & Constituents(tgid=25) ⓘ

Ingr?, 2,   Ingr↝, 7,  
Total Targets: 180

Scientific Paper Hit Count for: CRP, C-reactive protein
4 Magnesium
3 Thymoquinone
2 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
2 Flaxseed/Linseed
2 Selenium NanoParticles
2 Selenite (Sodium)
1 Anthocyanins
1 Ashwagandha(Withaferin A)
1 Berberine
1 Boron
1 Boswellia (frankincense)
1 Carvacrol
1 Camu camu
1 Celastrol
1 Curcumin
1 Chlorella (Chlorella vulgaris)
1 Spirulina(Arthrospira/Limnospira)
1 diet Fermented Foods
1 diet Short Term Fasting
1 Ellagic acid
1 Eurycomanone
1 Flaxseed Oil
1 Zinc
1 Quercetin
1 Silver-NanoParticles
1 Taurine
1 Urolithin
1 Vitamin C (Ascorbic Acid)
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:884  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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