Obesity Cancer Research Results

Obesity, Obesity: Click to Expand ⟱
Source:
Type:
Obesity
Scientific Papers found: Click to Expand⟱
7839- AO,  ISQ,    The Protective Effects of Acer okamotoanum and Isoquercitrin on Obesity and Amyloidosis in a Mouse Model
- in-vivo, AD, NA - in-vivo, Obesity, NA
*Dose↝, *Obesity↓, *Leptin↓, *adiP↑, *hepatoP↑, *PSEN1/PS1↓, *PSEN2/PS-2↓, *BACE/β-secretase↓, *eff↑,
5633- BCA,    Mechanisms Behind the Pharmacological Application of Biochanin-A: A review
- Review, Var, NA - Review, AD, NA
*AntiDiabetic↑, *neuroP↑, *toxicity↓, *CYP19↓, p‑Akt↓, mTOR↓, TumCCA↑, P21↑, Casp3↑, Bcl-2↑, Apoptosis↑, E-cadherin↓, TumMeta↓, eff↑, GSK‐3β↓, β-catenin/ZEB1↓, RadioS↑, ROS↑, Casp1↑, MMP2↓, MMP9↓, EGFR↓, ChemoSen↑, PI3K↓, MMPs↓, Hif1a↓, VEGF↓, *ROS↓, *Obesity↓, *cardioP↑, *NRF2↑, *NF-kB↓, *Inflam↓, *lipid-P↓, *hepatoP↑, *AST↓, *ALP↓, *Bacteria↓, *neuroP↑, *SOD↑, *GPx↑, *AChE↓, *BACE/β-secretase↓, *memory↑, *BioAv↓,
5872- CA,    Nrf2/ARE-Mediated Antioxidant Actions of Pro-Electrophilic Drugs
- Review, Nor, NA
*NRF2↑, *GSH↑, *neuroP↑, *Inflam↓, *cardioP↑, *Obesity↓, *angioG↓, chemoP↑, *NF-kB↓,
5861- CAP,    Anticancer Properties of Capsaicin Against Human Cancer
- Review, Var, NA
*antiOx↑, *Inflam↓, *Obesity↓, chemoPv↑, Apoptosis↑, selectivity↑, TRPV1↑, Ca+2↑, mtDam↑, Cyt‑c↑, P53↑, SIRT1↓, TumCCA↑, P21↑, CDK4↓, CDK6↓, cycE/CCNE↓, angioG↓, TumMeta↓,
5858- CAP,    Capsaicin as a Microbiome Modulator: Metabolic Interactions and Implications for Host Health
- Review, Nor, NA - Review, AD, NA
*BBB↓, *GutMicro↑, Obesity↓, *Inflam↓, *AntiCan↑, *TRPV1↑, *Ca+2↑, *antiOx↑, *cardioP↑, *BioAv↓, *Half-Life↓, *BioAv↝, *BioAv↑, *neuroP↑, Apoptosis↑, p38↑, ROS↑, MMP↓, MPT↑, Cyt‑c↑, Casp↑, TRIB3↑, NADH↓, SIRT1↓, TumCG↓, TumCMig↓, TOP1↓, TOP2↓, β-catenin/ZEB1↓, *ROS↓, *Aβ↓,
5854- CAP,    Pharmacological activity of capsaicin: Mechanisms and controversies (Review)
- Review, Var, NA - Review, AD, NA
Obesity↓, Half-Life↓, antiOx↑, TRPV1↑, STAT3↓, Ca+2↑, ROS↑, MMP↓, *neuroP↑, *tau↓, *Inflam↓, *ROS?,
5881- CAR,    Carvacrol—A Natural Phenolic Compound with Antimicrobial Properties
- Review, Nor, NA
*Bacteria↓, *Inflam↓, *SOD↑, *GPx↑, *GSR↑, *Catalase↑, *toxicity↓, *Pain↓, *other↑, *cardioP↑, *RenoP↑, *neuroP↑, *antiOx↑, *AntiDiabetic↑, *hepatoP↑, *Obesity↓, *AntiAg↑, *BioAv↓, BioAv↝, *OS↑, MMP↓, ROS↑, *MDA↓, *lipid-P↓, *COX2/PTGS2↓, *Dose↝,
5888- CAR,    Therapeutic application of carvacrol: A comprehensive review
- Review, Var, NA - Review, Stroke, NA - Review, Diabetic, NA - Review, Park, NA
*antiOx↑, *AntiCan↑, *AntiDiabetic↑, *cardioP↑, *Obesity↓, *hepatoP↑, *AntiAg↑, *Bacteria↓, *Imm↑, MMP2↓, MMP9↓, Apoptosis↓, MMP↓, ERK↓, PI3K↓, ALAT↓, *ROS↓, *Catalase↑, *SOD↑, *GPx↑, *AST↓, *LDH↓, *necrosis↓, ROS↑, TumCCA↑, CDK4↓, cycD1/CCND1↓, NOTCH↓, IL6↓, chemoP↑, *Pain↓, *neuroP↑, *TRPM7↓, *motorD↑, *NF-kB↓, *COX2/PTGS2↓, *MDA↓,
6650- Cen,    Therapeutic Potential of Centella asiatica and Its Triterpenes: A Review
- Review, AD, NA
*BioAv↝, *BioAv↝, *MDA↓, *GSH↑, *SOD↑, *AChE↓, *memory↑, *Ki-67↑, *Catalase↑, *PI3K↑, *BDNF↑, *NGF↑, *ROS↓, *NRF2↑, *HO-1↑, *NQO1↑, *ATP↑, *OCR↑, *TNF-α↓, *PP2A↑, *GSK‐3β↓, *Bcl-2↑, *TrkB↑, *NOTCH1↑, *SOX2↑, *Nestin↑, *MDA↓, *MAOA↓, *MAOB↓, *GPx↑, *cognitive↑, *ROS↓, *neuroP↑, *glucose↓, *ALAT↓, *AST↓, *PFK↓, *Weight↓, *Inflam↓, *AntiDiabetic↑, *Obesity↓, *Wound Healing↑, *cardioP↑, *GutMicro↑, *Sepsis↓, *BioAv↑,
6022- CGA,    Chlorogenic Acid: Recent Advances on Its Dual Role as a Food Additive and a Nutraceutical against Metabolic Syndrome
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiDiabetic↑, *Obesity↓, *Wound Healing↑, *BP↓, *Dose↝, *ROS↓, *Fas↓, *HMG-CoA↓, *GutMicro↑,
6011- CGA,    Chlorogenic Acid’s Role in Metabolic Health: Mechanisms and Therapeutic Potential
- Review, Nor, NA
*BioAv↓, *antiOx↑, *Inflam↓, *Bacteria↓, *hepatoP↑, *cardioP↑, *neuroP↑, *ROS↓, *NF-kB↓, *NRF2↑, *Obesity↓, *GutMicro↑, *AntiAg↑, *cardioP↑, *AntiDiabetic↑, *NLRP3↓, *OCLN↓, *VEGF↓, BioAv↝,
6023- CGA,    Pharmacological advances of the chlorogenic acids family: current insights and future research directions
- Review, AD, NA - Review, Park, NA - Review, IBD, NA
*Aβ↓, *neuroP↑, *cardioP↑, *GastroP↑, *RenoP↑, *hepatoP↑, *Obesity↓, *Bacteria↓, *BioAv↑, *BioAv↑, *BioAv↑, *ROS↓, *GutMicro↑, *IBI↑, *MCT1↓, *NF-kB↓, *DNMT1↓,
6025- Chit,    Glycated chitosan as a new non-toxic immunological stimulant
- vitro+vivo, Var, HeLa
*Imm↑, *BioAv↑, eff↑, *toxicity↓, *TNF-α↑, *Obesity↓,
6001- Chit,    Recent advances in engineering chitosan-based nanoplatforms in biotherapeutic multi-delivery for multi-targeted disease treatments: Promises and outlooks
- Review, Var, HepG2 - Review, AD, NA
TumVol↓, toxicity↓, Half-Life↑, eff↑, selectivity↑, Dose↝, *BDNF↑, *NRF2↑, *ROS↓, *neuroP↑, *memory↑, *cognitive↑, *Obesity↓,
5998- Chit,    Trial: Chitosan can help reduce AGE levels in patients with prostate cancer.
- Trial, Pca, NA
AGEs↓, Wound Healing↑, Obesity↓,
6081- CHL,    Enhancing Health Benefits through Chlorophylls and Chlorophyll-Rich Agro-Food: A Comprehensive Review
- Review, Nor, NA
*antiOx↑, *toxicity↓, *BioAv↓, *BioAv↑, *neuroP↑, *Obesity↓, *AntiCan↑, *TumCP↓, *PhotoS↑, *neuroP↑,
6093- CHOC,    The relevance of theobromine for the beneficial effects of cocoa consumption
- Review, Nor, NA - NA, Asthma, NA
*toxicity↓, *eff↑, *Half-Life↑, *eff↑, *Inflam↓, *HDL↑, *Obesity↓,
6084- CHOC,    Cocoa Polyphenols and Their Potential Benefits for Human Health
- Review, Nor, NA - Review, Stroke, NA - Review, IBD, NA
*lipid-P↓, *ROS↓, *Inflam↓, *BP↓, *cardioP↑, *chemoPv↑, *BioAv⇅, *antiOx↑, *Risk↓, *5LO↓, *AntiAg↑, *Imm↑, *NF-kB↓, *other↓, CYP1A1↓, COX2/PTGS2↓, *Obesity↓, *cognitive↑,
6626- Cic,  Ech,    Chicoric Acid Ameliorated Beta-Amyloid Pathology and Enhanced Expression of Synaptic-Function-Related Markers via L1CAM in Alzheimer’s Disease Models
- in-vivo, Nor, NA
*antiOx↑, *Obesity↓, *memory↑, *Aβ↓, *MAPK↓, *NF-kB↓, *iNOS↓, *COX2/PTGS2↓, *IL1β↓, *TNF-α↓, *NF-kB↓,
6632- Cic,    Chicoric Acid Ameliorates Lipopolysaccharide-Induced Oxidative Stress via Promoting the Keap1/Nrf2 Transcriptional Signaling Pathway in BV-2 Microglial Cells and Mouse Brain
- vitro+vivo, Nor, NA
*antiOx↑, *Obesity↓, *NRF2↑, *HO-1↑, *NQO1↑, *ROS↓, *GSH↑, *Catalase↑, *SOD↑, *ATP↑, *COX2/PTGS2↓, *iNOS↓, *neuroP↑,
6520- CRV,    Health Benefits and Pharmacological Properties of Carvone
- Review, Nor, NA
*Bacteria↓, *AntiFungal↑, *antiOx↑, *Inflam↓, AntiCan↑, *AntiDiabetic↑, *Obesity↓, TumCCA↑, *AntiArt↑, Imm↑, *P450↓, *GSR↑, GSTs↑, GSH↑, BAX↑, Casp3↑, TumCP↓, TumCMig↓, Apoptosis↑,
6207- CUR,    Enhancing the Bioavailability and Bioactivity of Curcumin for Disease Prevention and Treatment
- Review, Var, NA - Review, AD, NA
*AntiCan↑, *Obesity↓, *Inflam↓, *lipid-P↓, *BioAv↓, *BioAv↑, *BioAv↑, *BioAv↑, *BioAv↑, *BioAv↑, *ROS↓, *mt-SOD↑, *MDA↓, *BBB↓, *Aβ↓, *GSK‐3β↓, *tau↓, *neuroG↑, *memory↑, cardioP↑,
6710- dietF,    The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on fermented foods
- Review, Nor, NA
*other↝, *toxicity↓, *toxicity↓, *Obesity↓, *AntiDiabetic↑, *cardioP↑, *GutMicro↑, *Imm↑,
6711- dietF,    Gut-microbiota-targeted diets modulate human immune status
- Trial, Nor, NA
*GutMicro↑, *Inflam↓, *Imm↑, *Obesity↓, *AntiDiabetic↑, *AntiCan↑, *cardioP↑, *IL6↓, *IL10↓, *IL12↓,
6714- dietF,    Effects of Fermented Kimchi Consumption on Anthropometric and Blood Cardiometabolic Indicators: A Systematic Review and Meta-Analysis of Intervention Studies and Prospective Cohort Studies
- Review, Var, NA
Risk↓, *Obesity↓,
6716- dietF,    Current Research in Fermented Foods: Bridging Tradition and Science
- Review, Nor, NA
*GutMicro↑, *Inflam↓, *BP↓, *LDL↓, *HDL↑, *CRP↓, *IL6↓, *TNF-α↓, *Obesity↓, *AntiDiabetic↑, *cardioP↑, *GutMicro↑, *neuroP↑, *cognitive↑,
6281- DL,    Applications of Limonene in Neoplasms and Non-Neoplastic Diseases
- Review, Var, NA - Review, AD, NA - Review, Diabetic, NA
*antiOx↑, AntiTum↑, *AntiDiabetic↑, *neuroP↑, *GastroP↑, *ROS↓, *toxicity↓, *BioAv↑, ChemoSen↑, BAX↑, P53↓, Bcl-2↓, iNOS↓, COX2/PTGS2↓, eff↑, ROS↑, TumCCA↑, cycD1/CCND1↓, CycB/CCNB1↓, TumCMig↓, *lipid-P↓, *GSH↑, *SOD↑, *GPx↑, *hepatoP↑, *glucose↓, *AGEs↓, *Obesity↓, *Aβ↓, *AChE↓,
6366- DRE,    A comprehensive review of the benefits of Taraxacum officinale on human health
- Review, Var, NA
*diuretic↑, *hepatoP↑, *Imm↑, *Bacteria↓, *AntiArt↑, *AntiDiabetic↑, *Obesity↓, *antiOx↓, *AntiCan↑, Dose?,
6784- EGCG,    Dietary (−)-Epigallocatechin Gallate (EGCG): State-of-the-Art Advances in Bioactivities, Bioavailability Enhancement Strategies, and Applications in Nutrition and Health
- Review, Nor, NA
*antiOx↑, *Inflam↓, *AntiCan↑, *cardioP↑, *neuroP↑, *GutMicro↑, *AntiBio↑, *ROS↓, *TNF-α↓, *IL6↓, TumCP↓, *LDL↓, *NO↓, *Obesity↓, *p‑tau↓, *Aβ↓, *NRF2↑, *SOD↑, *Catalase↑, *GPx↑, *NLRP3↓, *mTOR↓, TumCCA↑, NRF2↓, Apoptosis↑, SIRT1↓, miR-25-5p↓, PARP↑, Casp3↑, Casp9↑, ER Stress↑, TumAuto↑, EMT↓, TumCI↓, TumCMig↓, TGF-β↓, Smad1↓, STAT3↓, VEGF↓, angioG↓, Imm↑, EGFR↓, *GutMicro↑, *Bacteria↓, *AntiViral↑, *BioAv↓, *BioAv↑, *eff↑, *BioAv↑, eff↑, ChemoSen↑, *toxicity↝,
6825- EMD,    Advances in the pharmacological effects and molecular mechanisms of emodin in the treatment of metabolic diseases
- Review, Nor, NA
*Inflam↓, *AntiTum↑, *Bacteria↓, *Imm↑, *glucose↓, *RenoP↑, *TLR4↓, *MyD88↓, *NLRP3↓, *NF-kB↓, *PI3K↓, *mTOR↓, *GSK‐3β↓, *Hif1a↓, *VEGF↓, *GutMicro↑, *Obesity↓, *AntiDiabetic↑, *AMPK↑, *PPARγ↑, *PPARγ↓, *toxicity↝, *hepatoP↑, *AST↓, *ALAT↓,
6981- Form,    Formononetin: a review of its source, pharmacology, drug combination, toxicity, derivatives, and drug delivery systems
- Review, Var, NA - Review, AD, NA - Review, PSA, NA
BioAv↝, *memory↑, *ROS↓, *AChE↓, *NF-kB↓, *Keap1↝, *NRF2↑, *Inflam↓, *PGC-1α↝, *HO-1↓, *p‑tau↓, *cognitive↑, *BDNF↑, *5HT↑, *Stroke↓, *PARP1↓, *AIF↓, *Casp3↓, NP/CIPN↓, *neuroP↑, *NGF↑, *TNF-α↓, *IL1β↓, *IL18↓, *IL6↓, *VCAM-1↓, *pol-M2 MC↑, *hepatoP↑, *AST↓, *ALAT↓, *LC3II↑, *Beclin-1/ATG6↑, *p62↑, *COX2/PTGS2↑, *MMP↑, *ATP↑, *GSH↑, *Catalase↑, *GPx↑, *MDA↓, *antiPs↑, *AntiDiabetic↑, *glucose↓, *Insulin↑, *GutMicro↑, *Obesity↓, COX2/PTGS2↓, cycD1/CCND1↓, TumCCA↑, EGFR↓, GSK‐3β↑, Mcl-1↓, *toxicity↓, TumCP↓, Hif1a↓, VEGF↓, ERK↓, LAMs↓, Cyt‑c↑, Casp9↑, Casp3↑, PARP↑, TumCD↑, mitA↑, BACH1↓, P53↓, ROS↑, PD-1↓, NF-kB↓, *Bacteria↓, *AntiViral↑, *mt-ROS?, *PI3K↓, *chemoP↑, ChemoSen↑, eff↑, *toxicity↓, *BioAv↑, *BioAv↑, *eff↑,
7028- GA,    Gallic acid: Pharmacological activities and molecular mechanisms involved in inflammation-related diseases
- Review, Nor, NA
*toxicity↓, *Inflam↓, *NF-kB↓, AntiTum↑, Bacteria↓, *AntiDiabetic↑, *Obesity↓, *AntiBio↑, *Stroke↓, *NO↓, *PGE2↓, *IL6↓, *MAPK↓, *TNF-α↓, *IL1β↓, *MCP1/CCL2↓, *ICAM-1↓, *TIMP1↓,
7094- GAR,    A multi-targeted approach of garcinol for obesity intervention: Mechanistic insights and possible clinical applications
- Review, Nor, NA
*Obesity↓, *Appetite↓, *GutMicro↑, BioAv↝,
7205- GBE,    Exploring the multifaceted role of ginkgolides and bilobalide from Ginkgo biloba in mitigating metabolic disorders
- Review, AD, NA
*antiOx↑, *Inflam↓, *neuroP↑, *ROS↓, *cardioP↑, *Obesity↓, *BioAv↓,
6571- Ger,    Unlocking the therapeutic potential of Geraniol: an alternative perspective for metabolic disease management
- Review, Obesity, NA
*lipidLev↓, *antiOx↓, Inflam↓, *ROS↓, *BioAv↑, *AntiDiabetic↑, *Obesity↓,
7482- H2,    Molecular Hydrogen Therapy: Mechanisms, Delivery Methods, Preventive, and Therapeutic Application
- Review, Var, NA - Review, IBD, NA - Review, Stroke, NA - Review, Sepsis, NA - Review, AD, NA
Dose↝, *Inflam↓, *IL1β↓, *IL6↓, *TNF-α↓, *neuroP↑, *mTOR↓, *IL10↑, *TGF-β↑, *Sepsis↓, *NRF2↑, *antiOx↑, *Catalase↑, *SOD↑, *GPx↑, *ROS↓, *HO-1↑, *PI3K↑, *Akt↑, *hepatoP↑, *MPO↓, *cardioP↑, CDK4↓, CDK6↑, CD47↓, PI3K↓, Akt↓, Hif1a↓, selectivity↑, *MMP↑, *ATP↑, *ER Stress↓, *CHOP/DDIT3↓, *Casp12↓, *GRP78/BiP↓, *p38↓, *p‑JNK↓, *LC3‑Ⅱ/LC3‑Ⅰ↑, *p‑eIF2α↓, *ATF4↓, *XBP-1↓, *Imm↑, *IFN-γ↓, *IL4↓, *GranB/GZMB↓, NK cell↑, radioP↑, *CD4+↑, CD8+↑, *Dose↝, *other↑, *Dose↝, *antiPs↑, *BioAv↝, *GutMicro↑, Dose↝, *IBI↑, TumCP↓, TumCI↓, TumCMig↓, CD8+↑, PGC-1α↑, Akt↓, SCD1↓, *MDA↓, eff↑, *APP↓, *BACE/β-secretase↓, *Aβ↓, *cognitive↑, *neuroP↑, NP/CIPN↓, *Stroke↓, *NLRP3↓, *ALAT↓, *AST↓, *LPS↓, *hepatoP↑, chemoP↑, *creat↓, *Urea↓, *RenoP↑, *eff↑, Apoptosis↑, XIAP↓, IAP2/BIRC3↓, TumVol↓, MALAT1↓, EZH2↓, miR-124-3p↓, eff↑, ChemoSen↑, *compII↑, *compIII↑, *LDL↓, *Obesity↓, QoL↑, PFS↑,
7487- H2,    A comprehensive review of molecular hydrogen as a novel nutrition therapy in relieving oxidative stress and diseases: Mechanisms and perspectives
- Review, Nor, NA
*Inflam↓, *antiOx↓, *Stress↓, *Dose↝, *cardioP↑, *GastroP↑, *BBB↑, *eff↑, *toxicity↓, *Dose↝, *hepatoP↑, *ROS↓, *SOD↑, *TBARS↓, *HDL↑, *LDL↓, *Obesity↓, *GSH↑, *TNF-α↓, *GutMicro↑, *DNAdam↓, *γH2AX↓, *p‑p38↓, *NF-kB↓,
7638- Ins,    d-Chiro-Inositol in Clinical Practice: A Perspective from the Experts Group on Inositol in Basic and Clinical Research (EGOI)
- Review, Nor, NA
*Insulin↝, *CYP19↓, *Dose↝, *Dose↝, *other↝, *Insulin↓, *IRes↓, *Obesity↓, *BioAv↝,
7917- IVT,    A review on the pharmacological effects of vitexin and isovitexin
- Review, Nor, NA - Review, AD, NA
*antiOx↑, *AntiCan↑, *Inflam↓, *neuroP↑, *AChE↓, *BChE↓, *BACE/β-secretase↓, *Stroke↓, *AntiAg↓, *AntiDiabetic↑, *AGEs↓, *IL1β↓, *IL6↓, *IL8↓, *TNF-α↓, *Obesity↓, *BioAv↝, *BioAv↓,
8108- L-Orn,    Safety assessment of L-ornithine oral intake in healthy subjects: a systematic review
- Review, Nor, NA
*toxicity↓, *toxicity↓, *GH↑, *Obesity↓, *NH3↓, *hepatoP↑, *Sleep↑, *fatigue↓,
8155- lamb,    Ethanol extract of Pinus koraiensis leaves containing lambertianic acid exerts anti-obesity and hypolipidemic effects by activating adenosine monophosphate-activated protein kinase (AMPK)
- vitro+vivo, Nor, 3T3
*p‑AMPK↑, *PPARγ↓, *CEBPA↓, *adiP↓, *Fas↓, *SREBP1/SREBF1↓, *HMGCR↓, *lipidLev↓, *TG/TAG↓, *Weight↓, *LDL↓, *Obesity↓,
8151- lamb,    Suppression of STAT3 Phosphorylation and RelA/p65 Acetylation Mediated by MicroRNA134 Plays a Pivotal Role in the Apoptotic Effect of Lambertianic Acid
- in-vitro, BC, MCF7 - in-vitro, Pca, DU145 - in-vitro, Pca, PC3 - in-vitro, BC, MDA-MB-231
TumCCA↑, cl‑PARP↑, p‑STAT3↓, NF-kB↓, XIAP?, survivin↓, Bcl-2↓, Bcl-xL↓, VEGF↓, COX2/PTGS2↓, cMyc↓, IL6↓, TNF-α↓, ac‑p65↑, Obesity↓, miR-134↑,
8150- lamb,    Reactive oxygen species dependent phosphorylation of the liver kinase B1/AMP activated protein kinase/ acetyl-CoA carboxylase signaling is critically involved in apoptotic effect of lambertianic acid in hepatocellular carcinoma cells
- in-vitro, HCC, HepG2 - in-vitro, HCC, SK-HEP-1
lipidLev↓, TumCCA↑, cl‑Casp3↑, cl‑PARP↑, AMPK↑, Akt↓, mTOR↓, Bcl-2↓, Bcl-xL↓, COX2/PTGS2↓, ROS↑, eff↓, p‑STK11/LKB1↑, p‑ACC↑, *Obesity↓, *Stress↓, *antiAll↑, tumCV↓, selectivity↑, TumCP↓,
8156- lamb,    A review on chemistry, source and therapeutic potential of lambertianic acid
- Review, Var, NA
*Obesity↓, *AntiCan↑, *AMPK↑, *β-HEX↓, NA↑, TumCCA↑, AMPK↑, ACC↑, p‑Akt↓, FOXM1↓, CycB/CCNB1↓, XIAP↓, Bcl-2↓, p‑STAT3↓, p‑NF-kB↓, Bcl-xL↓, survivin↓, VEGF↓, COX2/PTGS2↓, cMyc↓, IL6↓, TNF-α↓, ROS↑, STK11/LKB1↑, cl‑Casp3↑, cl‑PARP↑, eff↑, AR↓, TumCP↓, p‑P53↓, P21↓, p27/CDKN1B↓, cycD1/CCND1↓, CDK4↓, PSA↓, STAT3↓, ac‑p65↓, *antiAll↑,
8234- LCA,    Licochalcone A: A Potential Multitarget Drug for Alzheimer’s Disease Treatment
- Review, AD, NA
*neuroP↑, *PTP1B↓, *cognitive↑, *BDNF↑, *TrkB↝, *cJun↓, *p‑tau↓, *AChE↓, *Ach↑, *Aβ↓, *antiOx↑, *NRF2↑, *AntiViral↑, *Obesity↓, *PI3K↑, *Akt↑, *mTOR↑, *memory↑, *BBB↑,
8229- LCA,    Licochalcone A: a review of its pharmacology activities and molecular mechanisms
- Review, Nor, NA
*Inflam↓, *NO↓, *NF-kB↓, *TAC↑, Apoptosis?, TumCCA↑, TumCI↓, TumMeta↓, TumCP↓, MAPK↓, Akt↓, IL6↓, IL8↓, VEGFR2/KDR/Flk1↓, LC3II↑, PI3K↓, mTOR↓, mtDam↑, MMP↓, *NRF2↑, *PGE2↓, *Obesity↓, *SIRT1↑, *AMPK↑, *AntiFungal↑, *AntiP↑, *BMD↑, *GastroP↑,
1791- LEC,    Vegetable lecithins: A review of their compositional diversity, impact on lipid metabolism and potential in cardiometabolic disease prevention
- Review, Nor, NA
*BioEnh↑, *antiOx↑, *BioEnh↑, *LDL↓, *HDL∅, *Obesity↓, eff↑, GutMicro↝,
6767- Thyme,    Thymol, thyme, and other plant sources: Health and potential uses
- Review, Nor, NA
*AntiBio↑, *Inflam↓, *Imm↑, *other↝, *Half-Life↝, *Obesity↓, *GutMicro↑,
5904- TV,    Pharmacological Properties and Molecular Mechanisms of Thymol: Prospects for Its Therapeutic Potential and Pharmaceutical Development
- Review, Var, NA - Review, Stroke, NA - Review, Diabetic, NA - Review, Obesity, NA - Review, AD, NA - Review, Arthritis, NA
*antiOx↑, *ROS↓, *Inflam↓, *Bacteria↓, AntiTum↑, IronCh↑, *HDL↑, *LDL↓, *BioAv↝, *Half-Life↝, *BioAv↑, *SOD↑, *GPx↑, *GSTs↑, *eff↑, radioP↑, *MDA↓, *other↑, *COX1↓, *COX2/PTGS2↓, *AntiAg↑, *RNS↓, *NO↓, *H2O2↓, *NOS2↓, *NADH↓, *Imm↑, Apoptosis↑, TumCP↓, angioG↓, TumCMig↓, Ca+2↑, TumCCA↑, DNAdam↑, BAX↑, Casp9↑, Casp8↑, Casp3↑, cl‑PARP↑, AIF↑, i-ROS↑, MMP↓, Cyt‑c↑, APAF1↑, Ca+2↑, MMP9↓, MMP2↓, PKCδ↓, ERK↓, H2O2↑, BAX↑, Bcl-2↓, DNAdam↑, lipid-P↑, ChemoSen↑, chemoP↑, *cardioP↑, *SOD↑, *Catalase↑, *GPx↑, *GSH↑, *BP↓, *AntiDiabetic↑, *Obesity↓, RenoP↑, *GastroP↑, hepatoP↑, *AChE↓, *cognitive↑, *BChE↓, *other↓, *BioAv↑,
3146- VitC,    Vitamin C protects against hypoxia, inflammation, and ER stress in primary human preadipocytes and adipocytes
- in-vivo, Nor, NA
*Obesity↓, *ER Stress↓, *Inflam↓, Hif1a↓, VEGF↓, GLUT1↓, GRP78/BiP↓,

Showing Research Papers: 1 to 50 of 51
Page 1 of 2 Next

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 51

Pathway results for Effect on Cancer / Diseased Cells:


NA, unassigned(tgid=0) ⓘ

CD47↓, 1,   miR-124-3p↓, 1,   miR-134↑, 1,   NA↑, 1,   PFS↑, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 1,   CYP1A1↓, 1,   GSH↑, 1,   GSTs↑, 1,   H2O2↑, 1,   lipid-P↑, 1,   NADH↓, 1,   NRF2↓, 1,   ROS↑, 9,   i-ROS↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↑, 1,   MMP↓, 6,   MPT↑, 1,   mtDam↑, 2,   PGC-1α↑, 1,   XIAP?, 1,   XIAP↓, 2,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ACC↑, 1,   p‑ACC↑, 1,   ALAT↓, 1,   AMPK↑, 2,   cMyc↓, 2,   lipidLev↓, 1,   SCD1↓, 1,   SIRT1↓, 3,   STK11/LKB1↑, 1,   p‑STK11/LKB1↑, 1,  

Cell Death(tgid=5) ⓘ

Akt↓, 4,   p‑Akt↓, 2,   APAF1↑, 1,   Apoptosis?, 1,   Apoptosis↓, 1,   Apoptosis↑, 7,   BAX↑, 4,   Bcl-2↓, 5,   Bcl-2↑, 1,   Bcl-xL↓, 3,   Casp↑, 1,   Casp1↑, 1,   Casp3↑, 5,   cl‑Casp3↑, 2,   Casp8↑, 1,   Casp9↑, 3,   Cyt‑c↑, 4,   IAP2/BIRC3↓, 1,   iNOS↓, 1,   MAPK↓, 1,   Mcl-1↓, 1,   p27/CDKN1B↓, 1,   p38↑, 1,   survivin↓, 2,   TRPV1↑, 2,   TumCD↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

miR-25-5p↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

EZH2↓, 1,   tumCV↓, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↑, 1,   GRP78/BiP↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

LC3II↑, 1,   TumAuto↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 2,   P53↓, 2,   P53↑, 1,   p‑P53↓, 1,   PARP↑, 2,   cl‑PARP↑, 4,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK4↓, 4,   CycB/CCNB1↓, 2,   cycD1/CCND1↓, 4,   cycE/CCNE↓, 1,   mitA↑, 1,   P21↓, 1,   P21↑, 2,   TumCCA↑, 12,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

EMT↓, 1,   ERK↓, 3,   FOXM1↓, 1,   GSK‐3β↓, 1,   GSK‐3β↑, 1,   mTOR↓, 3,   NOTCH↓, 1,   PI3K↓, 4,   STAT3↓, 3,   p‑STAT3↓, 2,   TOP1↓, 1,   TOP2↓, 1,   TumCG↓, 1,  

Migration(tgid=13) ⓘ

BACH1↓, 1,   Ca+2↑, 4,   E-cadherin↓, 1,   LAMs↓, 1,   MALAT1↓, 1,   MMP2↓, 3,   MMP9↓, 3,   MMPs↓, 1,   PKCδ↓, 1,   Smad1↓, 1,   TGF-β↓, 1,   TRIB3↑, 1,   TumCI↓, 3,   TumCMig↓, 6,   TumCP↓, 8,   TumMeta↓, 3,   β-catenin/ZEB1↓, 2,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 3,   EGFR↓, 3,   Hif1a↓, 4,   VEGF↓, 6,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

GLUT1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

COX2/PTGS2↓, 6,   IL6↓, 4,   IL8↓, 1,   Imm↑, 2,   Inflam↓, 1,   NF-kB↓, 2,   p‑NF-kB↓, 1,   NK cell↑, 1,   ac‑p65↓, 1,   ac‑p65↑, 1,   PD-1↓, 1,   PSA↓, 1,   TNF-α↓, 2,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 1,   CDK6↓, 1,   CDK6↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↝, 4,   ChemoSen↑, 6,   Dose?, 1,   Dose↝, 3,   eff↓, 1,   eff↑, 10,   Half-Life↓, 1,   Half-Life↑, 1,   RadioS↑, 1,   selectivity↑, 4,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   AR↓, 1,   EGFR↓, 3,   EZH2↓, 1,   FOXM1↓, 1,   GutMicro↝, 1,   IL6↓, 4,   PSA↓, 1,   TRIB3↑, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 1,   AntiTum↑, 3,   cardioP↑, 1,   chemoP↑, 4,   chemoPv↑, 1,   hepatoP↑, 1,   NP/CIPN↓, 2,   Obesity↓, 4,   QoL↑, 1,   radioP↑, 2,   RenoP↑, 1,   Risk↓, 1,   toxicity↓, 1,   TumVol↓, 2,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

Bacteria↓, 1,   CD8+↑, 2,  
Total Targets: 169

Pathway results for Effect on Normal Cells:


NA, unassigned(tgid=0) ⓘ

antiAll↑, 2,   AntiArt↑, 2,   AntiBio↑, 3,   AntiP↑, 1,   compII↑, 1,   diuretic↑, 1,   IRes↓, 1,   PSEN1/PS1↓, 1,   PSEN2/PS-2↓, 1,   Stress↓, 2,   Stroke↓, 4,   β-HEX↓, 1,  

Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 3,   antiOx↑, 19,   Catalase↑, 8,   GPx↑, 10,   GSH↑, 7,   GSR↑, 2,   GSTs↑, 1,   H2O2↓, 1,   HDL↑, 4,   HDL∅, 1,   HO-1↓, 1,   HO-1↑, 3,   Keap1↝, 1,   lipid-P↓, 5,   MDA↓, 8,   MPO↓, 1,   NADH↓, 1,   NQO1↑, 2,   NRF2↑, 11,   RNS↓, 1,   ROS?, 1,   ROS↓, 20,   mt-ROS?, 1,   SOD↑, 11,   mt-SOD↑, 1,   TAC↑, 1,   TBARS↓, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

AIF↓, 1,   ATP↑, 4,   compIII↑, 1,   Insulin↓, 1,   Insulin↑, 1,   Insulin↝, 1,   MMP↑, 2,   OCR↑, 1,   PGC-1α↝, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

adiP↓, 1,   adiP↑, 1,   ALAT↓, 4,   AMPK↑, 3,   p‑AMPK↑, 1,   glucose↓, 4,   HMG-CoA↓, 1,   LDH↓, 1,   LDL↓, 7,   lipidLev↓, 2,   NH3↓, 1,   PFK↓, 1,   PPARγ↓, 2,   PPARγ↑, 1,   SIRT1↑, 1,   SREBP1/SREBF1↓, 1,  

Cell Death(tgid=5) ⓘ

Akt↑, 2,   Bcl-2↑, 1,   Casp12↓, 1,   Casp3↓, 1,   Fas↓, 2,   GranB/GZMB↓, 1,   iNOS↓, 2,   p‑JNK↓, 1,   MAPK↓, 2,   MCT1↓, 1,   necrosis↓, 1,   p38↓, 1,   p‑p38↓, 1,   TRPV1↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

Ach↑, 1,   cJun↓, 1,   other↓, 2,   other↑, 3,   other↝, 3,   PhotoS↑, 1,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   p‑eIF2α↓, 1,   ER Stress↓, 2,   GRP78/BiP↓, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↑, 1,   LC3‑Ⅱ/LC3‑Ⅰ↑, 1,   LC3II↑, 1,   p62↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,   DNMT1↓, 1,   PARP1↓, 1,   γH2AX↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CEBPA↓, 1,   GH↑, 1,   GSK‐3β↓, 3,   HMGCR↓, 1,   mTOR↓, 3,   mTOR↑, 1,   Nestin↑, 1,   neuroG↑, 1,   NOTCH1↑, 1,   PI3K↓, 2,   PI3K↑, 3,   SOX2↑, 1,   TRPM7↓, 1,  

Migration(tgid=13) ⓘ

5LO↓, 1,   AntiAg↓, 1,   AntiAg↑, 5,   APP↓, 1,   Ca+2↑, 1,   Ki-67↑, 1,   PTP1B↓, 1,   TGF-β↑, 1,   TIMP1↓, 1,   TumCP↓, 1,   VCAM-1↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 1,   ATF4↓, 1,   Hif1a↓, 1,   NO↓, 4,   VEGF↓, 2,  

Barriers & Transport(tgid=15) ⓘ

BBB↓, 2,   BBB↑, 2,   GastroP↑, 5,   IBI↑, 2,   OCLN↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 1,   COX1↓, 1,   COX2/PTGS2↓, 5,   COX2/PTGS2↑, 1,   CRP↓, 1,   ICAM-1↓, 1,   IFN-γ↓, 1,   IL10↓, 1,   IL10↑, 1,   IL12↓, 1,   IL18↓, 1,   IL1β↓, 5,   IL4↓, 1,   IL6↓, 7,   IL8↓, 1,   Imm↑, 10,   Inflam↓, 27,   LPS↓, 1,   pol-M2 MC↑, 1,   MCP1/CCL2↓, 1,   MyD88↓, 1,   NF-kB↓, 13,   PGE2↓, 2,   TLR4↓, 1,   TNF-α↓, 9,   TNF-α↑, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

5HT↑, 1,   AChE↓, 7,   BChE↓, 2,   BDNF↑, 4,   MAOA↓, 1,   NGF↑, 2,   tau↓, 2,   p‑tau↓, 3,   TrkB↑, 1,   TrkB↝, 1,  

Protein Aggregation(tgid=19) ⓘ

AGEs↓, 2,   Aβ↓, 8,   BACE/β-secretase↓, 4,   MAOB↓, 1,   NLRP3↓, 4,   PP2A↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

CYP19↓, 2,   Leptin↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 9,   BioAv↑, 20,   BioAv⇅, 1,   BioAv↝, 7,   BioEnh↑, 2,   Dose↝, 9,   eff↑, 8,   Half-Life↓, 1,   Half-Life↑, 1,   Half-Life↝, 2,   P450↓, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 4,   ALP↓, 1,   AST↓, 6,   BMD↑, 1,   BP↓, 4,   creat↓, 1,   CRP↓, 1,   GutMicro↑, 17,   IL6↓, 7,   Ki-67↑, 1,   LDH↓, 1,   NOS2↓, 1,   TG/TAG↓, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

AntiCan↑, 9,   AntiDiabetic↑, 18,   antiPs↑, 2,   AntiTum↑, 1,   Appetite↓, 1,   cardioP↑, 18,   chemoP↑, 1,   chemoPv↑, 1,   cognitive↑, 8,   fatigue↓, 1,   hepatoP↑, 14,   memory↑, 7,   motorD↑, 1,   neuroP↑, 23,   Obesity↓, 46,   OS↑, 1,   Pain↓, 2,   RenoP↑, 4,   Risk↓, 1,   Sleep↑, 1,   toxicity↓, 14,   toxicity↝, 2,   Weight↓, 2,   Wound Healing↑, 2,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 2,   AntiViral↑, 3,   Bacteria↓, 11,   Sepsis↓, 2,  
Total Targets: 228

Scientific Paper Hit Count for: Obesity, Obesity
4 diet Fermented Foods
4 lambertianic acid
3 Capsaicin
3 Chlorogenic acid
3 chitosan
2 Carvacrol
2 Chocolate
2 Cichoric acid / Chicoric acid
2 Hydrogen Gas
2 Isovitexin
2 Licochalcone A
1 Acer okamotoanum
1 isoquercitrin
1 Biochanin A
1 Carnosic acid
1 Centella asiatica / Gotu kola → asiaticoside
1 Chlorophyllin
1 Echinacea
1 Carvone
1 Curcumin
1 D-limonene
1 Dandelion Root
1 EGCG (Epigallocatechin Gallate)
1 Emodin
1 Formononetin
1 Gallic acid
1 Garcinol
1 Ginkgo biloba
1 Geraniol
1 Inositol
1 L-ornithine
1 Lecithin
1 Thyme
1 Thymol-Thymus vulgaris
1 Vitamin C (Ascorbic Acid)
1 Vitexin
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:930  State#:%  Dir#:1
  wNotes=0  sortOrder:rid,rpid

 

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