ChemoSen Cancer Research Results

ChemoSen, chemo-sensitization: Click to Expand ⟱
Source:
Type:
The effectiveness of chemotherapy by increasing cancer cell sensitivity to the drugs used to treat them, which is known as “chemo-sensitization”.

Possible Chemo-Sensitizers:
-Curcumin
-Resveratrol
-EGCG
-Quercetin
-Genistein
-Berberine
-Piperine: alkaloid from black pepper
-Ginsenosides: active components of ginseng
-Silymarin
-Allicin
-Lycopene
-Ellagic acid
-Caffeic acid phenethyl ester
-flavopiridol
-oleandrin
-Ursolic acid
-butein
-Betulinic acid



Scientific Papers found: Click to Expand⟱
5355- AL,    Mini-review: The health benefits and applications of allicin
- Review, Var, NA
*BioAv↑, *cardioP↑, *hepatoP↑, *RenoP↑, *Half-Life↝, *BioAv↓, *neuroP↑, *cognitive↑, *ROS↓, *lipid-P↓, *DNArepair↑, *ChemoSen↑,
1425- Bos,    Protective Effect of Boswellic Acids against Doxorubicin-Induced Hepatotoxicity: Impact on Nrf2/HO-1 Defense Pathway
- in-vivo, Nor, NA
*ChemoSen↑, *NRF2↑, *HO-1↑, *ROS↓, *lipid-P↓, *DNAdam↓,
8844- DIM,  I3C,    Unveiling the Multifaceted Pharmacological Actions of Indole-3-Carbinol and Diindolylmethane: A Comprehensive Review
- Review, Var, NA - Review, AD, NA - Review, Stroke, NA
*antiOx↑, *Inflam↓, *Apoptosis↓, *Imm↝, *BioAv↝, *Half-Life↝, *PKCδ↓, *TGF-β1↓, *PPARγ↓, *CEBPA↓, *FABP4↓, *AMPKα↑, *MCP1/CCL2↓, *IL6↓, *TNF-α↓, *Akt↑, *Inflam↓, *TMAO↓, *SREBF2⇅, *memfluid↑, *GutMicro↑, *Obesity↓, *hepatoP↑, *neuroP↑, *AntiAg↓, *Stroke↓, *AntiAg↓, *HDAC↑, *IL1β↓, *IL6↓, *iNOS↓, *IL4↑, *IL10↑, *Synergy↑, *compI↑, *ROS↓, *AChE↓, *BChE↓, *MAOA↓, *MAOB↓, *cognitive↑, *Analgesic↑, *Pain↓, *BDNF↑, *TrkB↑, *Akt↑, *antiOx↑, *Apoptosis↓, *cardioP↑, *chemoP↑, *AntiThr↑, *uPA↑, *NRF2↑, *ARE↑, *HO-1↑, *Bacteria↓, *TOP1↓, *AntiFungal↑, *AntiViral↑, *radioP↑, *Synergy↑, *hepatoP↑, *Diar↓, *ChemoSen↑, *Telomerase↓, *BioAv↓,
8135- LF,    Lactoferrin-A Regulator of Iron Homeostasis and Its Implications in Cancer
- Review, Var, NA - Review, AD, NA
IronCh↑, ROS↓, Imm↑, Inflam↓, *BBB↑, Iron↝, *Fenton↓, *ROS↓, *TAC↑, *SOD↑, *GPx↑, *GSH↑, *TBARS↓, *PTEN↓, *tau↓, *MAPK↓, *Aβ42↓, *Apoptosis↓, *Casp3↓, *Akt↑, *GutMicro↑, *Sepsis↓, *anemia↓, *IL6↓, *FPN↑, *TfR1/CD71↑, *Ferritin↓, *HemoG↑, *RBC↑, *eff↑, *BioAv↓, *BioAv↑, *BioAv↝, *ChemoSen↑, *BioAv↑, Ferroptosis↑,
8414- Lyco,    Exploring the Therapeutic Potential of Lycopene: Mechanisms, Biological Activities, and Health Benefits
- Review, Var, NA - Review, AD, NA
*ROS↓, *Inflam↓, *hepatoP↑, *cardioP↑, *neuroP↑, *AntiArt↑, *Obesity↓, *Wound Healing↑, *BioAv↑, *GSTs↑, *Trx1↑, *SOD↑, *Catalase↑, *ALAT↓, *LDH↓, *AST↓, *MDA↓, *cognitive↑, *memory↑, *NeuroI↓, *Aβ↓, *LRP1↑, *RAGE↓, *NRF2↑, *HO-1↑, tumCV?, Bax:Bcl2↑, DNAdam↑, Apoptosis↑, β-catenin/ZEB1↓, cMyc↓, cycD1/CCND1↓, ROS↓, TumCCA↑, Akt↓, *Synergy↑, *MDA↓, *NF-kB↓, *TGF-β↓, *Casp3↓, *Catalase↑, *GSH↑, *Bcl-2↑, *IL10↑, *MUC1↑, *IBI↑, *RenoP↑, *ChemoSen↑, *Synergy↑, *Synergy↑, *BMD↑,

Showing Research Papers: 1 to 5 of 5

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 5

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

Iron↝, 1,   ROS↓, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↑, 1,   Bax:Bcl2↑, 1,   Ferroptosis↑, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

cMyc↓, 1,   tumCV?, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

cycD1/CCND1↓, 1,   TumCCA↑, 1,  

Migration(tgid=13) ⓘ

β-catenin/ZEB1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

Imm↑, 1,   Inflam↓, 1,  
Total Targets: 15

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↑, 2,   ARE↑, 1,   Catalase↑, 2,   Fenton↓, 1,   GPx↑, 1,   GSH↑, 2,   GSTs↑, 1,   HO-1↑, 3,   lipid-P↓, 2,   MDA↓, 2,   NRF2↑, 3,   ROS↓, 5,   SOD↑, 2,   TAC↑, 1,   TBARS↓, 1,   Trx1↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

Ferritin↓, 1,   FPN↑, 1,   TfR1/CD71↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compI↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,   FABP4↓, 1,   SREBF2⇅, 1,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 3,   Bcl-2↑, 1,   Casp3↓, 2,   iNOS↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↑, 3,   AMPKα↑, 1,   MAPK↓, 1,   PKCδ↓, 1,   PTEN↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 1,   HDAC↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 1,   DNArepair↑, 1,   Telomerase↓, 1,   TOP1↓, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CEBPA↓, 1,  

Migration(tgid=13) ⓘ

AntiAg↓, 2,   LRP1↑, 1,   MUC1↑, 1,   TGF-β↓, 1,   TGF-β1↓, 1,   uPA↑, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 1,   IBI↑, 1,   memfluid↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

IL10↑, 2,   IL1β↓, 1,   IL4↑, 1,   IL6↓, 3,   Imm↝, 1,   Inflam↓, 3,   MCP1/CCL2↓, 1,   NeuroI↓, 1,   NF-kB↓, 1,   RAGE↓, 1,   TNF-α↓, 1,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 1,   BChE↓, 1,   BDNF↑, 1,   MAOA↓, 1,   MAOB↓, 1,   TrkB↑, 1,  

Protein Aggregation(tgid=19) ⓘ

Aβ↓, 1,   Aβ42↓, 1,   tau↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

PPARγ↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 3,   BioAv↑, 4,   BioAv↝, 2,   ChemoSen↑, 5,   eff↑, 1,   Half-Life↝, 2,   Synergy↑, 5,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   anemia↓, 1,   AST↓, 1,   BMD↑, 1,   Ferritin↓, 1,   HemoG↑, 1,   IL6↓, 3,   LDH↓, 1,   RAGE↓, 1,   RBC↑, 1,   TMAO↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 1,   AntiArt↑, 1,   cardioP↑, 3,   chemoP↑, 1,   cognitive↑, 3,   hepatoP↑, 4,   memory↑, 1,   neuroP↑, 3,   Obesity↓, 2,   Pain↓, 1,   radioP↑, 1,   RenoP↑, 2,   Stroke↓, 1,   Wound Healing↑, 1,  

Infection & Microbiome(tgid=24) ⓘ

AntiFungal↑, 1,   AntiViral↑, 1,   Bacteria↓, 1,   Diar↓, 1,   GutMicro↑, 2,   Sepsis↓, 1,  
Total Targets: 107

Scientific Paper Hit Count for: ChemoSen, chemo-sensitization
1 Allicin (mainly Garlic)
1 Boswellia (frankincense)
1 Diindolylmethane
1 Indole-3-carbinol
1 Lactoferrin/Talactoferrin
1 Lycopene
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:1106  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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