chemoP Cancer Research Results
chemoP, ChemoProtective: Click to Expand ⟱
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| Type: |
Protects normal cells against the effect of Chemo.
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Scientific Papers found: Click to Expand⟱
Apoptosis↑, TumCP↓, MAPK↓, PI3K↓, Akt↓, NF-kB↓, AntiCan↑, ChemoSen↑, TumCCA↑, Apoptosis↑, BioAv↑, selectivity↑, TGF-β↓, ROS↑, DNAdam↑, p‑P53↑, P21↑, cycD1/CCND1↓, cycE/CCNE↓, CDK4↓, CDK6↓, MMP↓, NF-kB↑, BAX↑, Bcl-2↓, ER Stress↑, Casp↑, AIF↑, Fas↑, Casp8↑, Cyt‑c↑, cl‑PARP↑, Ca+2↑, *NRF2↑, *chemoP↑, *GutMicro↑, CycB/CCNB1↑, H2S↑, HIF-1↓, RadioS↑,
*RenoP↑, *ROS↓, *antiOx↑, *Inflam↓, *Sepsis↓, *IronCh↑, *BUN↓, *creat↓, *TNF-α↓, *IL6↓, *IL1β↓, *MDA↓, *NRF2↑, *HO-1↑, *NQO1↑, *chemoP↑, *eff↑, *NF-kB↓,
*hs-CRP↓, *TNF-α↓, *SOD↑, *Catalase↑, *GPx↑, *cognitive↑, *memory↑, *Risk↓, *SAM-e↑, *NAD↝, *ATP↝, *Ca+2↝, HDAC↓, TumVol↓, IGF-1↓, PSA↓, Cyc↓, TumCMig↓, *serineP↓, HIF-1↓, *ChemoSideEff↓, *VitD↑, *Mag↑, *Synergy↑, Risk↓, *Inflam↓, *neuroP↑, *Calcium↑, *BMD↑, *chemoP↑, AntiCan↑, *Dose↑, *Dose↝, *BMPs↑, *testos↑, angioG↓, Apoptosis↑, *selectivity↑, *chemoPv↑,
*cardioP↑, *chemoP↑, *antiOx↑, *ROS↓, *toxicity↓, *DNAdam↓, *lipid-P↓, *ER Stress↓,
Apoptosis↑, TumCCA↑, TumMeta↓, TumCP↓, MAPK↓, PI3K↓, Akt↓, mTOR↓, eff↑, *Inflam↓, *antiOx↑, AXL↓, MDA↑, Casp3↑, Bcl-2↓, MMP2↓, MMP9↓, p‑JNK↑, BAX↑, MDA↓, TRPM7↓, MMP↓, Cyt‑c↑, Casp↑, cl‑PARP↑, ROS↑, CDK4↓, P21↑, F-actin↓, GSH↓, *SOD↑, *Catalase↑, *GPx↑, *GSR↑, *GSH↑, *lipid-P↓, *AST↓, *ALAT↓, *ALP↓, *LDH↓, DNAdam↑, AFP↓, VEGF↓, Weight↑, *chemoP↑, ROS↑,
AntiCan↑, *chemoP↑, TNF-α↓, COX2/PTGS2↓, IL6↓, eff↑, PD-L1↓, *cognitive↓, *Aβ↓, *TAC↑, *SOD↑, *eff↑, *eff↑, ChemoSen↑, tumCV↓, Apoptosis↑, ERK↓, chemoP↑, *GPx↑, *GSTs↑, *GSH↑, *SOD↑, *Catalase↑, *ROS↓, *lipid-P↓, *MDA↓, *Casp3↓, *HO-1↓, cardioP↑, radioP↑,
*FIS1↓, *SIRT3↑, *PTEN↓, *chemoP↑,
tumCV↓, selectivity↑, Ferroptosis↑, lipid-P↑, mt-ROS↑, ChemoSen↑, *toxicity↓, TumCG↓, Synergy↑, Synergy↑, Dose↝, mtDam↑, *Inflam↓, *chemoP↑, Dose↑,
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Review, |
Var, |
NA |
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- |
Review, |
AD, |
NA |
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- |
Review, |
Stroke, |
NA |
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*antiOx↑, *Inflam↓, *Apoptosis↓, *Imm↝, *BioAv↝, *Half-Life↝, *PKCδ↓, *TGF-β1↓, *PPARγ↓, *CEBPA↓, *FABP4↓, *AMPKα↑, *MCP1/CCL2↓, *IL6↓, *TNF-α↓, *Akt↑, *Inflam↓, *TMAO↓, *SREBF2⇅, *memfluid↑, *GutMicro↑, *Obesity↓, *hepatoP↑, *neuroP↑, *AntiAg↓, *Stroke↓, *AntiAg↓, *HDAC↑, *IL1β↓, *IL6↓, *iNOS↓, *IL4↑, *IL10↑, *Synergy↑, *compI↑, *ROS↓, *AChE↓, *BChE↓, *MAOA↓, *MAOB↓, *cognitive↑, *Analgesic↑, *Pain↓, *BDNF↑, *TrkB↑, *Akt↑, *antiOx↑, *Apoptosis↓, *cardioP↑, *chemoP↑, *AntiThr↑, *uPA↑, *NRF2↑, *ARE↑, *HO-1↑, *Bacteria↓, *TOP1↓, *AntiFungal↑, *AntiViral↑, *radioP↑, *Synergy↑, *hepatoP↑, *Diar↓, *ChemoSen↑, *Telomerase↓, *BioAv↓,
AntiCan↑, ChemoSen↑, Dose↝, *ROS↓, Apoptosis↑, selectivity↑, *toxicity↓, *chemoP↑, eff↓, ROS↑,
*antiOx↑, *Inflam↓, *Apoptosis↓, *NF-kB↓, *Cyt‑c↓, *DNAdam↓, *GSH↑, *SOD↑, *ALB↝, *creat↓, *BUN↓, *RenoP↑, *lipid-P↓, *TNF-α↓, *Casp3↓, *Casp9↓, *chemoP↑,
*antiOx↑, *AntiCan↑, TumCMig↓, angioG↓, ChemoSen↑, RadioS↑, *chemoP↑, *BioAv↓, eff↓, selectivity↑, MMP2↓, MMP9↓, VEGF↓, TumCCA↑, Apoptosis↑, ROS↑, BioAv↑,
AntiCan↑, *antiOx↑, *chemoP↑, *Inflam↓, TumCP↓, TumMeta↓, TumCCA↑, MAPK↑, BAX↑, Casp↑, ROS↑, *BioAv↓, other↝, TumCI↓, EMT↓, TumCG↑, Apoptosis↑, TumCP↑, MMP2↓, Casp3↑, ChemoSen↑, PI3K↓, Akt↓, Cyt‑c↑, cl‑PARP↑, MMP↓, Warburg↓, HK2↓, PKM2↓, LDHA↓, mtDam↑, Apoptosis↑, N-cadherin↓, Vim↓, E-cadherin↑, eff↑, eff↑, eff↑, toxicity↝, toxicity↑,
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Review, |
Var, |
NA |
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Review, |
AD, |
NA |
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Review, |
PSA, |
NA |
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BioAv↝, *memory↑, *ROS↓, *AChE↓, *NF-kB↓, *Keap1↝, *NRF2↑, *Inflam↓, *PGC-1α↝, *HO-1↓, *p‑tau↓, *cognitive↑, *BDNF↑, *5HT↑, *Stroke↓, *PARP1↓, *AIF↓, *Casp3↓, NP/CIPN↓, *neuroP↑, *NGF↑, *TNF-α↓, *IL1β↓, *IL18↓, *IL6↓, *VCAM-1↓, *pol-M2 MC↑, *hepatoP↑, *AST↓, *ALAT↓, *LC3II↑, *Beclin-1/ATG6↑, *p62↑, *COX2/PTGS2↑, *MMP↑, *ATP↑, *GSH↑, *Catalase↑, *GPx↑, *MDA↓, *antiPs↑, *AntiDiabetic↑, *glucose↓, *Insulin↑, *GutMicro↑, *Obesity↓, COX2/PTGS2↓, cycD1/CCND1↓, TumCCA↑, EGFR↓, GSK‐3β↑, Mcl-1↓, *toxicity↓, TumCP↓, Hif1a↓, VEGF↓, ERK↓, LAMs↓, Cyt‑c↑, Casp9↑, Casp3↑, PARP↑, TumCD↑, mitA↑, BACH1↓, P53↓, ROS↑, PD-1↓, NF-kB↓, *Bacteria↓, *AntiViral↑, *mt-ROS?, *PI3K↓, *chemoP↑, ChemoSen↑, Synergy↑, *toxicity↓, *BioAv↑, *BioAv↑, *Synergy↑, *antiAll↑,
*Inflam↓, *ROS↓, *BioAv↓, *GutMicro↑, *neuroP↑, *glucose↝, *AntiThr↑, *chemoP↑, *Half-Life↝, *BBB∅, *AntiAge↑, Risk↑,
*other↑, *PCNA↑, *SOD↑, *lipid-P↓, *NRF2↑, *Keap1↓, *chemoP↑,
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in-vitro, |
BC, |
MCF7 |
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in-vitro, |
Nor, |
MCF10 |
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ChemoSen↑, tumCV↓, Apoptosis↑, selectivity↑, *ROS↓, Synergy↑, *chemoP↑, Dose↝,
*ROS↓, *antiOx↑, *Inflam↓, *chemoP↑, AntiCan↑, ChemoSen↑, chemoP↑, *BUN↓, *creat↓, *TUNEL↓, *MDA↓, *SOD↑, *Catalase↑, *NRF2↑, *BNP↓, *AST↓, *ALAT↓, *TNF-α↓, *IL1β↓, *IL6↓, *Casp3↓, *Casp9↓, *GPx↑, *E-cadherin↑, *Vim↓, *α-SMA↓, *COL1↓, *cardioP↑, *hepatoP↑, *p‑mTOR↓, *EMT↓, eff∅, *LPS↓, *TLR4↓, radioP↑,
*Half-Life↓, *ROS↓, *selectivity↑, *SOD↑, *HO-1↑, *NRF2↑, *chemoP↑, *radioP↑, ROS↑, *Inflam↓, eff↑, *TNF-α↓, *IL6↓, *cl‑Casp8↑, *Bax:Bcl2↓, *Apoptosis↓, *cardioP↑, *hepatoP↑, *RenoP↑, *chemoP↑, eff↝, chemoP↑, radioP↑, Synergy↑, TumCG↓, Ki-67↓, VEGF↓, selectivity↑,
Dose↝, *chemoP↑,
*chemoP↑, *Apoptosis↓, *Inflam↓, *RenoP↑, *lipidLev↓, *PGC-1α↑, *PPARα↑, *CPT1A↑, *FAO↑,
*antiOx↑, *RenoP↑, *chemoP↑, *SIRT1↑, *SIRT6↑, *NRF2↑, *HO-1↑, *NQO1↑, *NOX4↓, *ROS↓, *MPO↓, *MDA↓, *SOD↑, *GSH↑,
*BioAv↑, *chemoP↑, *ROS↓, *cardioP↑, *AntiDiabetic↑, *Dose↝, *antiAll↑,
*ROS↓, *NO↓, *chemoP↑, *MAPK↓, *Bax:Bcl2↓, *Apoptosis↓, *RenoP↑,
*Dose↝, *ROS↓, *Inflam↓, *Apoptosis↓, *eff↑, *chemoP↑, *ER Stress↓,
*Dose↝, *GSSG↓, *GGT/CD224↓, *NF-kB↓, *GSH↑, *GPx↑, *GSR↑, *GSTA1↑, *chemoP↑,
*chemoP↑,
*antiOx↑, *AntiTum↑, HMGB1↓, COX2/PTGS2↓, PGE2↓, TumCP↓, TumCCA↑, Synergy↑, MMP↓, p‑P53↑, BAX↑, cl‑PARP↑, proCasp3↑, proCasp8↑, proCasp9↑, ROS↑, TumAuto↑, MMP9↓, TumMeta↓, PI3K↓, Akt↓, eff↑, *chemoP↑, *NRF2↑, *NF-kB↓,
*Ingr↝, *AntiCan↑, *AntiDiabetic↑, *AntiBio↑, *Inflam↓, *antiAll↑, *hepatoP↑, *cough?, *SoreThr?, *toxicity↝, *cardioP↑, *BioAv↝, *PGE2↓, *COX2/PTGS2↓, *AntiAg↑, *ROS↓, *NLRP3↓, *NF-kB↓, *AP-1↓, TumCCA↑, Apoptosis↑, TumMeta↑, *Dose↝, *Dose↝, Ingr↝, TumAuto↑, LC3II↑, PI3K↓, Akt↓, mTOR↓, *cognitive↑, *BloodF↑, ChemoSen↑, ROS↓, *chemoP↑, ROS↑, tumCV↓, MMP↓, *AntiBio↑, *toxicity↝,
Dose↝, toxicity↓, INF-γ↝, other↑, *ROS↓, Imm↑, WBC↑, Neut↑, T-Cell↑, *antiOx↑, *GSH↑, *chemoP↑, *RenoP↑, *hepatoP↑, BUN↓, creat↓, ALAT↓, AST↓, RBC↑, PC↑, Mucositis↓, *AntiBio↑, *AntiViral↑, *AntiFungal↑, *Inflam↓,
RenoP↑, Dose↝, *TLR4↓, *MyD88↓, *TRIF↓, *TNF-α↓, *IL1β↓, *IL6↓, *NF-kB↓, *chemoP↑, *Casp3↓, *Casp9↓, *BAX↓, *Bcl-2↑, ChemoSen↑, *cardioP?, *hepatoP↑, *Apoptosis↓, *antiOx↑, *Inflam↓, *ROS↓, *BUN?, *creat↓, *GSH↑, *SOD↑, *Catalase↑, *MDA↓, *NADPH↓, *NRF2↑, *HO-1↑,
*ROS↓, *antiOx↑, *chemoP↑, *Inflam↓,
tumCV↓, Dose↝, Apoptosis↑, ROS↑, i-Iron↓, *Ca+2↓, *Iron↑, *chemoP↑, ROS↓, ChemoSen↑, selectivity↑,
*neuroP↑, *Inflam↓, *antiOx↑, *chemoP↑, *NRF2↑, *HO-1↑, *SOD↑, *Catalase↑, *GPx↑, *GSH↑, *ROS↓, *MDA↓, *NO↓, *TLR4↓, *NF-kB↓, *ERK↓, *TNF-α↓, *IL1β↓, *IL6↓, *iNOS↓, *COX2/PTGS2↓, *NLRP3↓,
*Inflam↓, *antiOx↑, *Dose↝, *Urea↓, *creat↓, *ROS↓, *NRF2↑, *HO-1↑, *NR1H4↑, *RenoP↑, *TNF-α↓, *IL6↓, *ERK↓, *VCAM-1↓, *NF-kB↓, *chemoP↑,
*antiOx↑, *Inflam↓, *Apoptosis↓, *Dose?, *SOD↑, *GPx↑, *NRF2↑, *HO-1↑, *MDA↓, *other↑, *Ferroptosis↓, *Iron↓, *ROS↓, *other↓, ChemoSen↑, *chemoP↑, *selectivity↑,
*Dose?, *lipid-P↓, *SOD↑, *Catalase↑, *GPx↑, *testos↑, *GPx4↓, *chemoP↑,
TumCCA↑, Apoptosis↑, ER Stress↑, UPR↑, CHOP/DDIT3↑, ROS↑, Bcl-2↓, NOX4↑, Hif1a↓, MMP2↓, MMP↓, VEGF↓, Akt↓, NF-kB↓, p65↓, SIRT3↓, mTOR↓, Catalase↓, SOD2↓, FASN↓, STAT3↓, HDAC2↓, HDAC3↓, BAD↑, BAX↑, Bak↑, Casp3↑, Casp9↑, PARP↑, P53↑, P21↑, p27/CDKN1B↑, Half-Life↝, BioAv↓, BioAv↓, selectivity↑, RadioS↑, *ROS↓, *GSH↑, *MDA↓, *SOD↑, *Catalase↑, *NRF2↑, *chemoP↑, *Inflam↓, PPARγ↑,
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Review, |
Var, |
NA |
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Review, |
AD, |
NA |
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*antiOx↑, *ROS↓, *chemoP↑, TumCG↓, *cognitive↑, *MMPs↓, *PGE2↓, *AP-1↓, *5LO↓, *COX1↓, *other↑, *other↑, *other↑, *SOD↑, *Catalase↑, *GSTs↑, *GSR↑, *other↑, *Weight↓, *BioEnh↑, *BioAv↑, *Synergy↑, *CYP3A2↓, *neuroP↑, *BP↓, *other↑,
*Dose↝, *BioAv↓, *BioAv↓, *BioAv↓, *BioAv↓, *BioAv↝, TumCP↓, Risk↓, *radioP↑, chemoPv↑, TumCCA↑, GSK‐3β↑, Wnt↓, β-catenin/ZEB1↓, ROS↑, BAX↑, Casp3↑, Casp8↑, Casp9↑, PARP↑, Beclin-1/ATG6↑, ATG5↑, LC3II↑, DNMT1↓, P21↑, CDK1↑, CycB/CCNB1↓, TNF-α↑, VEGF↓, IL1β↓, NF-kB↓, AP-1↓, MYCN↓, AMPK↑, MAPK↓, PI3K↓, Akt↓, cMET↓, P-gp/ABCB1↓, MRP1/ABCC1↓, ABCG2↓, MMPs↓, TNF-α↓, iNOS↓, COX2/PTGS2↓, angioG↓, STAT3↓, *chemoP↑, *ROS↓, *MDA↓, *P53↓, *Casp3↓, *Casp9↓, *JNK↓, *TNF-α↓, *p38↓, *MAPK↓, GSH↓, ChemoSen↑, *hepatoP↑, *COX1↓, *COX2/PTGS2↓, *15-LOX/ALOX15↓, RenoP↑, *toxicity↓,
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Review, |
Nor, |
NA |
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Review, |
IBD, |
NA |
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*antiOx↑, *antiAll↑, *Inflam↓, *AntiTum↑, *Bacteria↓, *AntiViral↑, *BioAv↓, *AntiArt↑, *PLA2↓, *chemoP↑, *ROS↓, *Casp3↓, *TNF-α↓, *NF-kB↓, *cardioP↑, *Stroke↓, *TG/TAG↓, *FFA/NEFA↓, *LDL↓, *HDL↑, *AntiDiabetic↑, *MPO↓, *NF-kB↓, *BioAv↓, *BioAv↝,
*GSH↑, *MDA↑, *other?, *other?, *chemoP↑,
*NRF2↑, *antiOx↑, *chemoP↑, *Inflam↓, *BioAv↑, Synergy↑, *NQO1↑, TNF-α↓, IL6↓, *GSH↑, *ROS↓, *MDA↓, Synergy↑, *hepatoP↑, *GPx↑, *SOD↑, *Catalase↑, *HO-1↑, *neuroP↑,
*antiOx↑, *chemoP↑, *NRF2↑,
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Review, |
Nor, |
NA |
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Review, |
Arthritis, |
NA |
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*hepatoP↑, *Inflam↓, *chemoP↑, *glucose↓, *antiOx↑, *ROS↓, *ACC↓, *FASN↓, *radioP↑, *NF-kB↓, *TGF-β↓, *AST↓, *α-SMA↝, *Synergy↑, *neuroP↑, Synergy↑, ROS↓,
ROS⇅, *antiOx↑, *SOD↑, *MPO↑, *neuroP↑, *chemoP↑, *radioP↑, NF-kB↓, IAP1↓, IAP2/BIRC3↓, XIAP↓, Bcl-xL↓, survivin↓, COX2/PTGS2↓, MMP9↓, VEGF↓, ROS↑, P21↑, HDAC↓, GSH↓, GADD45A↑, AIF↑, STAT3↓,
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Review, |
AD, |
NA |
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- |
Review, |
Stroke, |
NA |
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- |
Review, |
ostP, |
NA |
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Review, |
IBD, |
NA |
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*MitoP↓, *Strength↑, *PINK1↑, *PARK2↑, *Inflam↓, *COX2/PTGS2↓, *IL1β↓, *IL6↓, *TNF-α↓, *OS↑, *cardioP↑, *memory↑, *neuroG↑, *neuroP↑, *Cartilage↑, *Inflam↓, *RenoP↑, *BioAv↑, *Dose↝, *Half-Life↑, *NRF2↑, *GutMicro↑, *chemoP↑,
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Review, |
AD, |
NA |
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Review, |
Var, |
NA |
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*antiOx↑, *Inflam↓, *AntiCan↑, *Bacteria↓, *neuroP↑, *Obesity↓, *cardioP↑, *ROS↓, *MMP↑, *ATP↑, *MFN2↑, *DRP1/DNM1L↓, *FOXO3↑, *NRF2↑, *Ferroptosis↓, *GPx4↑, TumCP↓, HMGB1↓, PI3K↓, Akt↓, Hif1a↓, CDK1↓, CycB/CCNB1↓, TumCCA↑, Apoptosis↑, P53↑, NF-kB↓, ERK↓, p‑PI3K↓, miR-34a↑, Apoptosis↑, CSCs?, *MAPK↓, *HO-1↑, *hepatoP↑, *AMPK↑, *Akt↑, *GSK‐3β↑, *chemoP↑, *Casp3↓, *IRes↝, *GlucoseCon↑, ChemoSen↑, *GSH↑, *SOD↑, *ATF2↑, *GPx↑, *GSTs↑, *AntiAge↑, *Stroke↓, *AChE↓, *ACE/ACE1↓, *ACE2↓, *GutMicro↑, *MPO↓, *H+/K+-ATPase↓, *AntiDiabetic↑, *GLUT4↑, *Obesity↓, *HH↓, *RenoP↑, *BioAv↓, *BioAv↝, *BioAv↑,
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in-vitro, |
Nor, |
RAW264.7 |
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*iNOS↓, *COX2/PTGS2↓, *EP2↓, TumCP↓, selectivity↑, Apoptosis↑, *chemoP↑, *Inflam↓,
Showing Research Papers: 1 to 49 of 49
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 49
Pathway results for Effect on Cancer / Diseased Cells:
Redox & Oxidative Stress(tgid=1) ⓘ
Catalase↓, 1, GSH↓, 3, i-Iron↓, 1, lipid-P↑, 1, MDA↓, 1, MDA↑, 1, NOX4↑, 1, ROS↓, 3, ROS↑, 14, ROS⇅, 1, mt-ROS↑, 1, SOD2↓, 1,
Mitochondria & Bioenergetics(tgid=3) ⓘ
mtDam↑, 2, SIRT3↓, 1,
Core Metabolism/Glycolysis(tgid=4) ⓘ
ALAT↓, 1, AMPK↑, 1, FASN↓, 1, GSK‐3β↑, 2, H2S↑, 1, HK2↓, 1, LDHA↓, 1, PKM2↓, 1, Warburg↓, 1,
Cell Death(tgid=5) ⓘ
AIF↑, 2, Apoptosis↑, 16, BAD↑, 1, Bak↑, 1, BAX↑, 6, Bcl-2↓, 3, Bcl-xL↓, 1, Casp↑, 3, Casp3↑, 5, proCasp3↑, 1, Casp8↑, 2, proCasp8↑, 1, Casp9↑, 3, proCasp9↑, 1, Cyt‑c↑, 4, Fas↑, 1, Ferroptosis↑, 1, IAP1↓, 1, IAP2/BIRC3↓, 1, iNOS↓, 1, Mcl-1↓, 1, survivin↓, 1, TumCD↑, 1, XIAP↓, 1,
Kinase & Signal Transduction(tgid=6) ⓘ
Akt↓, 8, cMET↓, 1, EGFR↓, 1, ERK↓, 3, p‑JNK↑, 1, MAPK↓, 3, MAPK↑, 1, mTOR↓, 3, PI3K↓, 7, p‑PI3K↓, 1, STAT3↓, 3,
Transcription & Epigenetics(tgid=7) ⓘ
DNMT1↓, 1, HDAC↓, 2, HDAC2↓, 1, HDAC3↓, 1, miR-34a↑, 1, MYCN↓, 1, other↑, 1, other↝, 1, tumCV↓, 5,
Protein Folding & ER Stress(tgid=8) ⓘ
CHOP/DDIT3↑, 1, ER Stress↑, 2, UPR↑, 1,
Autophagy & Lysosomes(tgid=9) ⓘ
ATG5↑, 1, Beclin-1/ATG6↑, 1, LC3II↑, 2, TumAuto↑, 2,
DNA Damage & Repair(tgid=10) ⓘ
DNAdam↑, 2, P53↓, 1, P53↑, 2, p‑P53↑, 2, PARP↑, 3, cl‑PARP↑, 4,
Cell Cycle & Senescence(tgid=11) ⓘ
CDK1↓, 1, CDK1↑, 1, CDK4↓, 2, CDK6↓, 1, Cyc↓, 1, CycB/CCNB1↓, 2, CycB/CCNB1↑, 1, cycD1/CCND1↓, 2, cycE/CCNE↓, 1, GADD45A↑, 1, Ki-67↓, 1, mitA↑, 1, P21↑, 5, p27/CDKN1B↑, 1, TumCCA↑, 10,
Proliferation, Differentiation & Cell State(tgid=12) ⓘ
CSCs?, 1, IGF-1↓, 1, Ki-67↓, 1, TumCG↓, 3, TumCG↑, 1, TumCP↓, 8, TumCP↑, 1, Wnt↓, 1,
Migration(tgid=13) ⓘ
AP-1↓, 1, AXL↓, 1, BACH1↓, 1, Ca+2↑, 1, E-cadherin↑, 1, EMT↓, 1, F-actin↓, 1, LAMs↓, 1, MMP2↓, 4, MMP9↓, 4, MMPs↓, 1, N-cadherin↓, 1, TGF-β↓, 1, TumCI↓, 1, TumCMig↓, 2, TumMeta↓, 3, TumMeta↑, 1, Vim↓, 1, β-catenin/ZEB1↓, 1,
Angiogenesis & Vasculature(tgid=14) ⓘ
angioG↓, 3, HIF-1↓, 2, Hif1a↓, 3, VEGF↓, 7,
Barriers & Transport(tgid=15) ⓘ
MMP↓, 6, TRPM7↓, 1,
Immune & Inflammatory Signaling(tgid=16) ⓘ
COX2/PTGS2↓, 5, HMGB1↓, 2, IL1β↓, 1, IL6↓, 2, Imm↑, 1, INF-γ↝, 1, Neut↑, 1, NF-kB↓, 6, NF-kB↑, 1, p65↓, 1, PD-1↓, 1, PD-L1↓, 1, PGE2↓, 1, PSA↓, 1, T-Cell↑, 1, TNF-α↓, 3, TNF-α↑, 1,
Hormonal & Nuclear Receptors(tgid=20) ⓘ
PPARγ↑, 1,
Drug Metabolism & Resistance(tgid=21) ⓘ
ABCG2↓, 1, BioAv↓, 2, BioAv↑, 2, BioAv↝, 1, ChemoSen↑, 15, Dose↑, 1, Dose↝, 7, eff↓, 2, eff↑, 7, eff↝, 1, eff∅, 1, Half-Life↝, 1, MRP1/ABCC1↓, 1, P-gp/ABCB1↓, 1, RadioS↑, 3, selectivity↑, 9, Synergy↑, 9,
Clinical Biomarkers(tgid=22) ⓘ
AFP↓, 1, ALAT↓, 1, AST↓, 1, BUN↓, 1, creat↓, 1, EGFR↓, 1, IL6↓, 2, PC↑, 1, PD-L1↓, 1, PSA↓, 1, RBC↑, 1, WBC↑, 1,
Functional Outcomes(tgid=23) ⓘ
AntiCan↑, 6, cardioP↑, 1, chemoP↑, 3, chemoPv↑, 1, Mucositis↓, 1, NP/CIPN↓, 1, radioP↑, 3, RenoP↑, 2, Risk↓, 2, Risk↑, 1, toxicity↓, 1, toxicity↑, 1, toxicity↝, 1, TumVol↓, 1, Weight↑, 1,
Ingredients & Constituents(tgid=25) ⓘ
Ingr↝, 1,
Total Targets: 191
Pathway results for Effect on Normal Cells:
Redox & Oxidative Stress(tgid=1) ⓘ
antiOx↑, 24, ARE↑, 1, Catalase↑, 11, GPx↑, 11, GPx4↓, 1, GPx4↑, 1, GSH↑, 13, GSR↑, 3, GSSG↓, 1, GSTs↑, 3, HDL↑, 1, HO-1↓, 2, HO-1↑, 10, Iron↓, 1, Iron↑, 1, Keap1↓, 1, Keap1↝, 1, lipid-P↓, 6, MDA↓, 11, MDA↑, 1, MPO↓, 3, MPO↑, 1, NOX4↓, 1, NQO1↑, 3, NRF2↑, 18, ROS↓, 28, mt-ROS?, 1, SAM-e↑, 1, SOD↑, 18, TAC↑, 1,
Metal & Cofactor Biology(tgid=2) ⓘ
IronCh↑, 1,
Mitochondria & Bioenergetics(tgid=3) ⓘ
compI↑, 1, DRP1/DNM1L↓, 1, FIS1↓, 1, Insulin↑, 1, MFN2↑, 1, PGC-1α↑, 1, PGC-1α↝, 1, PINK1↑, 1, SIRT3↑, 1,
Core Metabolism/Glycolysis(tgid=4) ⓘ
15-LOX/ALOX15↓, 1, 5LO↓, 1, ACC↓, 1, ALAT↓, 3, AMPK↑, 1, ATP↑, 2, ATP↝, 1, CPT1A↑, 1, FABP4↓, 1, FAO↑, 1, FASN↓, 1, FFA/NEFA↓, 1, glucose↓, 2, glucose↝, 1, GlucoseCon↑, 1, GSK‐3β↑, 1, LDL↓, 1, lipidLev↓, 1, NAD↝, 1, NADPH↓, 1, PLA2↓, 1, SIRT1↑, 1, SREBF2⇅, 1,
Cell Death(tgid=5) ⓘ
AIF↓, 1, Apoptosis↓, 9, BAX↓, 1, Bax:Bcl2↓, 2, Bcl-2↑, 1, Casp3↓, 8, cl‑Casp8↑, 1, Casp9↓, 4, Cyt‑c↓, 1, Ferroptosis↓, 2, iNOS↓, 3, p38↓, 1, TUNEL↓, 1,
Kinase & Signal Transduction(tgid=6) ⓘ
Akt↑, 3, AMPKα↑, 1, ERK↓, 2, JNK↓, 1, MAPK↓, 3, p‑mTOR↓, 1, PI3K↓, 1, PKCδ↓, 1, PTEN↓, 1,
Transcription & Epigenetics(tgid=7) ⓘ
AntiThr↑, 2, ATF2↑, 1, FOXO3↑, 1, HDAC↑, 1, other?, 2, other↓, 1, other↑, 7,
Protein Folding & ER Stress(tgid=8) ⓘ
ER Stress↓, 2,
Autophagy & Lysosomes(tgid=9) ⓘ
Beclin-1/ATG6↑, 1, LC3II↑, 1, MitoP↓, 1, p62↑, 1, PARK2↑, 1,
DNA Damage & Repair(tgid=10) ⓘ
DNAdam↓, 2, P53↓, 1, PARP1↓, 1, PCNA↑, 1, SIRT6↑, 1, Telomerase↓, 1, TOP1↓, 1,
Proliferation, Differentiation & Cell State(tgid=12) ⓘ
BMPs↑, 1, CEBPA↓, 1, EP2↓, 1, HH↓, 1, neuroG↑, 1,
Migration(tgid=13) ⓘ
AntiAg↓, 2, AntiAg↑, 1, AP-1↓, 2, Ca+2↓, 1, Ca+2↝, 1, Cartilage↑, 1, COL1↓, 1, E-cadherin↑, 1, EMT↓, 1, MMPs↓, 1, serineP↓, 1, TGF-β↓, 1, TGF-β1↓, 1, uPA↑, 1, Vim↓, 1, α-SMA↓, 1, α-SMA↝, 1,
Angiogenesis & Vasculature(tgid=14) ⓘ
NO↓, 2, VCAM-1↓, 2,
Barriers & Transport(tgid=15) ⓘ
BBB∅, 1, GLUT4↑, 1, H+/K+-ATPase↓, 1, memfluid↑, 1, MMP↑, 2,
Immune & Inflammatory Signaling(tgid=16) ⓘ
COX1↓, 2, COX2/PTGS2↓, 5, COX2/PTGS2↑, 1, IL10↑, 1, IL18↓, 1, IL1β↓, 7, IL4↑, 1, IL6↓, 10, Imm↝, 1, Inflam↓, 29, LPS↓, 1, pol-M2 MC↑, 1, MCP1/CCL2↓, 1, MyD88↓, 1, NF-kB↓, 12, NLRP3↓, 2, PGE2↓, 2, TLR4↓, 3, TNF-α↓, 13, TRIF↓, 1, VitD↑, 1,
Cellular Microenvironment(tgid=17) ⓘ
GGT/CD224↓, 1,
Synaptic & Neurotransmission(tgid=18) ⓘ
5HT↑, 1, AChE↓, 3, BChE↓, 1, BDNF↑, 2, MAOA↓, 1, MAOB↓, 1, NGF↑, 1, TrkB↑, 1,
Protein Aggregation(tgid=19) ⓘ
Aβ↓, 1, p‑tau↓, 1,
Hormonal & Nuclear Receptors(tgid=20) ⓘ
ACE/ACE1↓, 1, ACE2↓, 1, BNP↓, 1, NR1H4↑, 1, PPARα↑, 1, PPARγ↓, 1, testos↑, 2,
Drug Metabolism & Resistance(tgid=21) ⓘ
BioAv↓, 11, BioAv↑, 7, BioAv↝, 5, BioEnh↑, 1, ChemoSen↑, 1, CYP3A2↓, 1, Dose?, 2, Dose↑, 1, Dose↝, 9, eff↑, 4, GSTA1↑, 1, Half-Life↓, 1, Half-Life↑, 1, Half-Life↝, 2, selectivity↑, 3, Synergy↑, 6,
Clinical Biomarkers(tgid=22) ⓘ
ALAT↓, 3, ALB↝, 1, ALP↓, 1, AST↓, 4, BloodF↑, 1, BMD↑, 1, BP↓, 1, BUN?, 1, BUN↓, 3, Calcium↑, 1, creat↓, 5, hs-CRP↓, 1, IL6↓, 10, IRes↝, 1, LDH↓, 1, Mag↑, 1, TG/TAG↓, 1, TMAO↓, 1, Urea↓, 1, VitD↑, 1,
Functional Outcomes(tgid=23) ⓘ
Analgesic↑, 1, AntiAge↑, 2, antiAll↑, 4, AntiArt↑, 1, AntiCan↑, 3, AntiDiabetic↑, 5, antiPs↑, 1, AntiTum↑, 2, cardioP?, 1, cardioP↑, 9, chemoP↑, 50, chemoPv↑, 1, ChemoSideEff↓, 1, cognitive↓, 1, cognitive↑, 5, cough?, 1, hepatoP↑, 12, memory↑, 3, neuroP↑, 11, Obesity↓, 4, OS↑, 1, Pain↓, 1, radioP↑, 5, RenoP↑, 10, Risk↓, 1, SoreThr?, 1, Strength↑, 1, Stroke↓, 4, toxicity↓, 6, toxicity↝, 2, Weight↓, 1,
Infection & Microbiome(tgid=24) ⓘ
AntiBio↑, 3, AntiFungal↑, 2, AntiViral↑, 4, Bacteria↓, 4, Diar↓, 1, GutMicro↑, 6, Sepsis↓, 1,
Ingredients & Constituents(tgid=25) ⓘ
Ingr↝, 1,
Total Targets: 248
Scientific Paper Hit Count for: chemoP, ChemoProtective
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:1 prod#:% Target#:1171 State#:% Dir#:2
wNotes=0 sortOrder:rid,rpid
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