Imm Cancer Research Results

Imm, immunostimulatory: Click to Expand ⟱
Source:
Type:
Enhance the immune response in patients.
Scientific Papers found: Click to Expand⟱
5444- AG,    A Systematic Review of Phytochemistry, Pharmacology and Pharmacokinetics on Astragali Radix: Implications for Astragali Radix as a Personalized Medicine
- Review, Var, NA
*Imm↑, *antiOx↑, *Inflam↓, AntiTum↑, eff↑, chemoP↑, Dose↝, TumCMig↓, TumCP↓, Akt↓, GSK‐3β↓, MMP2↓, MMP9↓, EMT↓, PI3K↓, Akt↓, NF-kB↓, Inflam↓, TGF-β1↓, TNF-α↓, IL6↓, Fas↓, FasL↓, NOTCH1↓, JNK↓, TumCG↓,
7402- Amla,    Traditional knowledge to clinical trials: A review on therapeutic actions of Emblica officinalis
- Review, Var, NA
*Synergy↑, *antiOx↑, *AntiCan↑, *Imm↑, *Inflam↓, *AntiArt↑, *Dose↝, *VitC↑, radioP↑, *cardioP↑, *GastroP↑, *Wound Healing↑, *Diar↓, eff↑, NK cell↑, BAX↑, Bcl-2↓, TumCCA↑, Dose↝,
6401- ANE,    Anethole and Its Role in Chronic Diseases
- Review, Var, NA - Review, PSA, NA
*BioAv↝, *other↝, CompStab↓, TNF-α↓, IL10↑, CXCR4↓, MMP2↓, MMP9↓, TIMP1↑, NF-kB↓, AP-1↓, STAT↓, JNK↓, ERK↓, MAPK↓, PI3K↓, Akt↓, JAK↓, *AntiDiabetic↓, *neuroP↑, *Imm↑, chemoP↑, *AntiThr↑, *AntiAg↑, *antiOx↑, *SOD↑, *GSH↑, *Wound Healing↑, chemoPv↑, *GSTs↑, *NF-kB↓,
4814- ASTX,    Chemopreventive and therapeutic efficacy of astaxanthin against cancer: A comprehensive review
- Review, Var, NA
Apoptosis↑, EMT↓, AntiCan↑, *cardioP↑, *neuroP↑, TumCG↓, *antiOx↑, *Bacteria↓, *Imm↑, *hepatoP↑, *AntiDiabetic↑, ROS↓, *chemoPv↑,
5365- AV,    Aloe Vera Polysaccharides as Therapeutic Agents: Benefits Versus Side Effects in Biomedical Applications
- Review, Nor, NA - Review, IBD, NA - Review, Diabetic, NA
*Wound Healing↑, *Imm↑, *antiOx↑, *AntiDiabetic↑, *AntiCan↑, *Inflam↓, *NF-kB↓, *COX2/PTGS2↓, *5LO↓, *IL1β↓, *IL6↓, *TNF-α↓, *IL10↑, *other↓, *ROS↓, *SOD↑, *Catalase↑, *GPx↑, *lipid-P↓, *DNAdam↓, *GutMicro↑, *ZO-1↑, AntiTum↑, Casp3↑, Casp9↑, angioG↓, MMPs↓, VEGF↓, NK cell↑,
5371- AV,    Assessment of the immunomodulatory effect of Aloe vera polysaccharides extracts on macrophages functions
- Study, Nor, NA
*eff↑, *IL6↑, *toxicity↓, *Imm↑,
5573- B-Gluc,    Continuous Exposure to Non-Soluble β-Glucans Induces Trained Immunity in M-CSF-Differentiated Macrophages
- in-vitro, Nor, NA
*Dectin1↑, *Imm↑, *TNF-α↓,
5574- B-Gluc,    Beta Glucan: Health Benefits in Obesity and Metabolic Syndrome
- Review, Obesity, NA
*BioAv↑, *toxicity↓, *Imm↑, *eff↑, *Risk↓, *Weight↓, *eff↝, *BP↓, *GutMicro↑, *eff↓,
2775- Bos,    The journey of boswellic acids from synthesis to pharmacological activities
- Review, Var, NA - Review, AD, NA - Review, PSA, NA
ROS↑, ER Stress↑, TumCG↓, Apoptosis↑, Inflam↓, ChemoSen↑, Casp↑, ERK↓, cl‑PARP↑, AR↓, cycD1/CCND1↓, VEGFR2/KDR/Flk1↓, CXCR4↓, radioP↑, NF-kB↓, VEGF↓, P21↑, Wnt↓, β-catenin/ZEB1↓, Cyt‑c↑, MMP2↓, MMP1↓, MMP9↓, PI3K↓, MAPK↓, JNK↑, *5LO↓, *NRF2↑, *HO-1↑, *MDA↓, *SOD↑, *hepatoP↑, *ALAT↓, *AST↓, *LDH↑, *CRP↓, *COX2/PTGS2↓, *GSH↑, *ROS↓, *Imm↑, *Dose↝, *eff↑, *neuroP↑, *cognitive↑, *IL6↓, *TNF-α↓, *AntiArt↑, *AntiDiabetic↑, *antiAll↑,
5708- Brut,    Clinical application of bergamot (Citrus bergamia) for reducing high cholesterol and cardiovascular disease markers
- Review, Nor, NA
*Imm↑, *cardioP↑, *LDL↓, toxicity↓,
6542- BSB,    Health Benefits, Pharmacological Effects, Molecular Mechanisms, and Therapeutic Potential of α-Bisabolol
- Review, Var, NA - Review, Park, NA - Review, AD, NA
AntiCan↑, *neuroP↑, *cardioP↑, *AntiBio↑, *BioAv↑, *toxicity↓, *BioAv↑, *motorD↑, *SOD↑, *Catalase↑, *Keap1↑, *MDA↓, *GSH↑, *IL1β↓, *IL6↓, *TNF-α↓, *iNOS↓, *COX2/PTGS2↓, *lipid-P↓, *Cyt‑c↓, *ROS↓, *MMP↑, *antiOx↑, *AChE↓, *Apoptosis↓, *BAX↓, *Casp3↓, *Bcl-2↑, *BACE/β-secretase↓, *BChE↓, *eff↑, *Aβ↓, *ATP↑, RadioS↑, Cyt‑c↑, Casp3↑, Casp8↑, Casp9↑, Apoptosis↑, PARP↑, BAX↑, BID↑, NF-kB↑, Fas↑, EGFR↑, TIMP2↑, XIAP↓, COX2/PTGS2↓, Bak↓, Bcl-2↓, P53↑, HER2/EBBR2↓, FGF↓, CEA↓, Akt↓, TumCCA↑, *Imm↑, *CD4+↑, *CD8+↑, *BBB↑, *Pain↓, *cardioP↑, *TBARS↓, *SOD↑, *Catalase↑, *GSH↑, *AntiBio↑, *AntiFungal↑, *GastroP↑, *RenoP↑, *creat↓, *uricA↓, *Inflam↓, *iNOS↓, *COX2/PTGS2↓, *TNF-α↓, *IL6↑, *MMP13↓,
5755- CA,    Caffeic Acid as a Promising Natural Feed Additive: Advancing Sustainable Aquaculture
- Review, Nor, NA
*Imm↑, *Inflam↓, *Bacteria↓, *eff↑, *ROS↓, *MDA↓, *Catalase↑, *GSH↑, *TAC↑, *NF-kB↓, *NLRP3↓, *Synergy↑, *AST↓, *ALAT↓, *SOD↑, *GSTA1↑,
5772- CAPE,    The Pluripotent Activities of Caffeic Acid Phenethyl Ester
- Review, Var, NA
*Bacteria↓, *AntiCan↑, *Imm↑, *Wound Healing↑, *NF-kB↓, *5LO↓, *AntiDiabetic↑, ChemoSen↑, selectivity↑, chemoPv↑,
5770- CAPE,    Caffeic acid phenethyl ester is a potent and specific inhibitor of activation of nuclear transcription factor NF-kappa B
- in-vitro, Nor, NA
*NF-kB↓, *Imm↑, *Inflam↓,
5888- CAR,    Therapeutic application of carvacrol: A comprehensive review
- Review, Var, NA - Review, Stroke, NA - Review, Diabetic, NA - Review, Park, NA
*antiOx↑, *AntiCan↑, *AntiDiabetic↑, *cardioP↑, *Obesity↓, *hepatoP↑, *AntiAg↑, *Bacteria↓, *Imm↑, MMP2↓, MMP9↓, Apoptosis↓, MMP↓, ERK↓, PI3K↓, ALAT↓, *ROS↓, *Catalase↑, *SOD↑, *GPx↑, *AST↓, *LDH↓, *necrosis↓, ROS↑, TumCCA↑, CDK4↓, cycD1/CCND1↓, NOTCH↓, IL6↓, chemoP↑, *Pain↓, *neuroP↑, *TRPM7↓, *motorD↑, *NF-kB↓, *COX2/PTGS2↓, *MDA↓,
5913- Cats,    Cat's claw inhibits TNFalpha production and scavenges free radicals: role in cytoprotection
- Review, Nor, NA
*Inflam↓, *NF-kB↓, *DPPH↓, *TNF-α↓, *Imm↑,
6254- CBC/D,    Cynanchum auriculatum Royle ex Wight., Cynanchum bungei Decne. and Cynanchum wilfordii (Maxim.) Hemsl.: Current Research and Prospects
- Review, Var, NA
*neuroP↑, *Imm↑, *Inflam↓, CSCs↓, HH↓, Gli↓, AST↓, ALAT↓, MDA↓, hepatoP↑, *NRF2↑, *HO-1↑, NF-kB?, GSK‐3β↓, β-catenin/ZEB1↓, COX2/PTGS2↓, MMP2↑, MMP9↓, BioAv↑,
6662- Cen,    Assessment report on Centella asiatica (L.) Urban, herba
- Review, Nor, NA
*cognitive↑, *Inflam↓, *AntiBio↑, *Imm↑, *antiOx↑, *Wound Healing↑, *cardioP↑, *SOD↑, *Catalase↑, *GPx↑, *GSTs↑, *MDA↓, *lipid-P↓, *ROS↓, *memory↑, *GABA↑, *antiPs↑, *BioAv↝,
6661- Cen,    Centella asiatica - A review of its medicinal uses and pharmacological effects
- Review, AD, NA - Review, Var, NA
*memory↑, *BioAv↑, *Wound Healing↑, TumCP↓, selectivity↑, *Imm↑,
6648- Cen,    Centella asiatica (L.) Urban: From Traditional Medicine to Modern Medicine with Neuroprotective Potential
- Review, AD, NA
*neuroP↑, *Aβ↓, *ROS↓, *Wound Healing↑, *memory↑, *Inflam↓, *hepatoP↑, *Imm↑, *cardioP↑, *AntiDiabetic↑, *AntiFungal↑, *antiOx↑, *Dose↝, *AChE↓, *BChE↓, *Tyro3↓, *lipid-P↓,
6021- CGA,    Chlorogenic acid for cancer prevention and therapy: Current status on efficacy and mechanisms of action
- in-vitro, Var, NA
*hepatoP↑, *Bacteria↓, *Imm↑, *antiOx↑, *AntiDiabetic↓, *AntiCan↑, TumCCA↑, Apoptosis↑, TumCP↓,
6025- Chit,    Glycated chitosan as a new non-toxic immunological stimulant
- vitro+vivo, Var, HeLa
*Imm↑, *BioAv↑, Synergy↑, *toxicity↓, *TNF-α↑, *Obesity↓,
5987- Chit,    Chitin, Chitosan, and Glycated Chitosan Regulate Immune Responses: The Novel Adjuvants for Cancer Vaccine
- Review, Var, NA
other↝, other↝, *Weight↝, *toxicity↓, *Bacteria↓, *BioAv↑, DDS↑, *Wound Healing↑, *other↝, *Imm↑, eff↑, *BioAv↝, *BioAv↑, eff↑, NK cell↑, IL2↑, IFN-γ↑, IL10↑,
5994- Chit,    Anticancer Activity of Chitosan, Chitosan Derivatives, and Their Mechanism of Action
- Review, Var, NA
angioG↓, *Imm↑, *antiOx↑, selectivity↑, other↝, toxicity↓, BioAv↑, eff↝, Half-Life↑, MPT↑, MMP9↓, lipid-P↑, EPR↑, NK cell↑, Casp3↑, Casp8↑, TumCCA↑, ROS↑, DDS↑, VEGF↓, TIMP1↑, ChemoSen↑, eff↑,
5990- Chit,    Chitosan Nanoparticles for Targeted Cancer Therapy: A Review of Stimuli-Responsive, Passive, and Active Targeting Strategies
- Review, Var, NA
DDS↑, eff↓, *Bacteria↓, *antiOx↑, *Wound Healing↑, *Imm↑, TumCP↓, TumMeta↓, angioG↓, Apoptosis↑, ROS↑, ER Stress↑, BioAv↑, Half-Life↑, eff↑, EPR↑, ChemoSen↑, eff↑,
6071- CHL,    First-in-human clinical trial of high-dose sodium copper chlorophyllin: Pharmacology and efficacy as a dual immunomodulatory/antiviral agent
- Trial, Nor, NA
*Dose↑, *toxicity↓, *Imm↑,
6084- CHOC,    Cocoa Polyphenols and Their Potential Benefits for Human Health
- Review, Nor, NA - Review, Stroke, NA - Review, IBD, NA
*lipid-P↓, *ROS↓, *Inflam↓, *BP↓, *cardioP↑, *chemoPv↑, *BioAv⇅, *antiOx↑, *Risk↓, *5LO↓, *AntiAg↑, *Imm↑, *NF-kB↓, *other↓, CYP1A1↓, COX2/PTGS2↓, *Obesity↓, *cognitive↑,
7433- Chy,    Evaluation of Cyavanaprāśa on Health and Immunity related Parameters in Healthy Children: A Two Arm, Randomized, Open Labeled, Prospective, Multicenter, Clinical Study
- Trial, Nor, NA
*Dose↝, *QoL↑, *Imm↑,
7436- Chy,  Amla,    A Review on the Role of Amla and Chyawanprash in Immunity Enhancement and Disease Prevention
- Review, Nor, NA
*VitC↑, *memory↑, *Imm↑, *NK cell↑, *antiOx↑, *neuroP↑, *cognitive↑,
7435- Chy,    Golden Ager Chyawanprash with Meager Evidential Base from Human Clinical Trials
- Review, Nor, NA
*Dose↝, *antiOx↑, *Inflam↓, *Imm↑, *QoL↑, *Dose↑, *Dose↝,
6627- Cic,    Determination of Cichoric Acid as a Biomarker in Echinacea Purpurea Cultivated in Iran Using High Performance Liquid Chromatography
- Study, Nor, NA
*Imm↑, *eff↑, *Dose↝,
6370- CPLE,    Delving into the Therapeutic Potential of Carica papaya Leaf against Thrombocytopenia
- Review, Var, NA
CIT↓, *Imm↑, *AntiDiabetic↑, *AntiCan↑, angioG↓, *Bacteria↓, *antiOx↑,
6202- Cuc,    Cucurbitacins as potential anticancer agents: new insights on molecular mechanisms
- Review, Var, NA
*Inflam↓, *antiOx↑, *hepatoP↑, AntiTum↑, AntiCan↑, *chemoPv↑, *AntiDiabetic↑, *Imm↑, Hif1a↓, P-gp/ABCB1↓, mTORC1↓, ERK↓, Akt↓, Casp3↑, Casp7↑, ATP↓, RadioS↑, ChemoSen↑,
9091- CV,    Chlorella vulgaris as a functional food and nutraceutical: bioactive composition, health-promoting mechanisms, applications, and current challenges
- Review, Nor, NA
*Ingr↝, *antiOx↑, *AntiBio↑, *Inflam↓, *Imm↑,
9109- CV,    Salivary secretory immunoglobulin A secretion increases after 4-weeks ingestion of chlorella-derived multicomponent supplement in humans: a randomized cross over study
- Trial, Nor, NA
*Dose↝, *IgA↑, *Imm↑,
6663- DFE,    Nutraceuticals of Phoenix dactylifera L.: Physicochemistry, Nutritional Value and Therapeutic Potential
- Review, Nor, NA - Review, AD, NA
*antiOx↑, *Inflam↓, *AntiBio↑, *AntiDiabetic↑, *AntiCan↑, *AntiArt↑, *neuroP↑, *hepatoP↑, *GastroP↑, *other↝, *cardioP↑, *cognitive↑, *ROS↓, *memory↑, *other↝, *SOD↑, *Catalase↑, *GSH↑, *GA↑, *Catechins↑, *FA↑, *QC↑, Api↑, *CA↑, *Imm↑, *Phen↑, *IL1β↓, *TGF-β↓, *COX1↓, *COX2/PTGS2↓, TumCP↓, Casp3↑, TumMeta↓, *GutMicro↑,
6667- DFE,    Immunostimulant effect of dates (Phoenix dactylifera) on humoral and cellular immunity cells and their functions
- in-vivo, Nor, NA
*Imm↑, *Inflam↓, *Flav↑,
6710- dietF,    The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on fermented foods
- Review, Nor, NA
*other↝, *toxicity↓, *toxicity↓, *Obesity↓, *AntiDiabetic↑, *cardioP↑, *GutMicro↑, *Imm↑,
6711- dietF,    Gut-microbiota-targeted diets modulate human immune status
- Trial, Nor, NA
*GutMicro↑, *Inflam↓, *Imm↑, *Obesity↓, *AntiDiabetic↑, *AntiCan↑, *cardioP↑, *IL6↓, *IL10↓, *IL12↓,
6715- dietF,    Are Fermented Foods Effective against Inflammatory Diseases?
- Review, Nor, NA
*Imm↑, *GastroP↑, *Inflam↓, AntiCan↑, *AntiBio↑, *hepatoP↑, *CD4+↑, *IFN-γ↓, *IL17↓, *GutMicro↑, *antiOx↑, *AST↓, *ALAT↓, *HDL↑, *LDL↓, *ROS↓, *lipid-P↓, *Inflam↓, *Aβ↓,
6288- DL,    From Citrus to Clinic: Limonene’s Journey Through Preclinical Research, Clinical Trials, and Formulation Innovations
- Review, Var, NA - Review, AD, NA
other↑, DDS↑, *antiOx↑, *Inflam↓, *AntiDiabetic↑, *neuroP↑, *Imm↑, *Wound Healing↑, *other↑, *BioAv↑, *ROS↓, *SOD↑, *Catalase↑, *GSH↑, *DNAdam↓, *AntiDiabetic↑, Casp3↑, Casp9↑, BAX↑, Bcl-2↓, *AChE↓, *BChE↓, *Aβ↓, *ROS↓, *toxicity?,
6348- DRE,    New prospects in oncotherapy: bioactive compounds from Taraxacum officinale
- Review, Var, NA
Ingr↝, TumCP↓, toxicity↓, *AntiDiabetic↑, *antiOx↑, *hepatoP↑, *diuretic↑, *Inflam↓, *neuroP↑, *Imm↑, eff↑, Apoptosis↑, tumCV↓, selectivity↑, TumCMig↓, EMT↓, MMP2↓, MMP9↓, Wnt↓, β-catenin/ZEB1↓, PI3K↓, Akt↓, JNK↓, ERK↓,
6357- DRE,    New Perspectives on the Effect of Dandelion, Its Food Products and Other Preparations on the Cardiovascular System and Its Diseases
- Review, Nor, NA
*cardioP↑, *Ingr↝, *Ingr↝, *toxicity∅, *toxicity↓, *BP↓, *Inflam↓, *Bacteria↓, *Imm↑, *lipid-P↓, *AST↓, *ALAT↓, *AntiAg↑, *ROS↓, *AntiThr↑,
6365- DRE,    AN OVERVIEW OF THERAPEUTIC POTENTIALS OF TARAXACUM OFFICINALE (DANDELION): A TRADITIONALLY VALUABLE HERB WITH A REACH HISTORICAL BACKGROUND
- Review, Var, NA
*Inflam↓, *AntiTum↑, *Imm↑, *antiOx↑, *AntiDiabetic↑, *diuretic↑, *RenoP↑, *hepatoP↑, *neuroP↑, AntiTum↑, TNF-α↑, IL1β↑, Apoptosis↑, MMP2↓, MMP9↑, Synergy↑, Diff↑, *ROS↓, *HO-1↑, *NRF2↑, *lipid-P↓,
6362- DRE,    Taraxacum spp. in vitro and in vivo anticancer activity – A review
- Review, Var, NA
tumCV↓, *AntiDiabetic↑, *Imm↑,
6366- DRE,    A comprehensive review of the benefits of Taraxacum officinale on human health
- Review, Var, NA
*diuretic↑, *hepatoP↑, *Imm↑, *Bacteria↓, *AntiArt↑, *AntiDiabetic↑, *Obesity↓, *antiOx↓, *AntiCan↑, Dose?,
6769- Ech,    Echinacea
- Review, Nor, NA
*Imm↑,
6616- Ech,    Natural killer cells from aging mice treated with extracts from Echinacea purpurea are quantitatively and functionally rejuvenated
- in-vivo, Nor, NA
*NK cell↑, *Imm↑,
6614- Ech,    Echinacea: a Miracle Herb against Aging and Cancer? Evidence In vivo in Mice
- in-vivo, Var, NA
*Imm↑, *AntiAge↑, OS↑, NK cell↑, PGE2↓, 5LO↓, COX2/PTGS2↓, Dose↝, Synergy↑,
6612- Ech,    Safety and Efficacy Profile of Echinacea purpurea to Prevent Common Cold Episodes: A Randomized, Double-Blind, Placebo-Controlled Trial
- Trial, Nor, NA
*Imm↑, Dose↝, eff↑,

Showing Research Papers: 1 to 50 of 83
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* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 83

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

H2O2↑, 1,   lipid-P↑, 2,   MDA↓, 1,   ROS↓, 1,   ROS↑, 10,   i-ROS↑, 1,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

PGC-1α↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 1,   ALAT↓, 2,   ATP↓, 1,   GSK‐3β↓, 3,   SCD1↓, 1,  

Cell Death(tgid=5) ⓘ

AIF↑, 1,   APAF1↑, 1,   Apoptosis↓, 1,   Apoptosis↑, 13,   Bak↓, 1,   BAX↓, 1,   BAX↑, 5,   Bax:Bcl2↑, 1,   Bcl-2↓, 6,   Bcl-xL↓, 1,   BID↑, 1,   BIM↑, 1,   Casp↑, 4,   Casp3↑, 8,   Casp7↑, 1,   Casp8↑, 4,   Casp9↑, 5,   Cyt‑c↑, 4,   Fas?, 1,   Fas↓, 1,   Fas↑, 1,   FasL↓, 1,   IAP1↓, 1,   IAP2/BIRC3↓, 2,   survivin↓, 2,   XIAP↓, 3,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 10,   p‑Akt↓, 1,   EGFR↑, 1,   ERK↓, 6,   p‑ERK↓, 1,   HER2/EBBR2↓, 1,   JAK↓, 1,   JAK3↓, 1,   JNK↓, 3,   JNK↑, 1,   MAPK↓, 2,   mTOR↓, 1,   p‑mTOR↓, 1,   PI3K↓, 8,   PKCδ↓, 1,   PTEN↑, 2,   STAT↓, 1,   STAT3↓, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

cMyc↓, 1,   EZH2↓, 1,   FOXO1↑, 1,   FOXO3↑, 1,   FOXO4↑, 1,   HES1↓, 1,   miR-124-3p↓, 1,   miR-21↓, 1,   other↑, 1,   other↝, 4,   tumCV↓, 2,  

Protein Folding & ER Stress(tgid=8) ⓘ

ER Stress↑, 2,   HSP70/HSPA5↑, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

Beclin-1/ATG6↑, 1,   LC3B-II↑, 1,   p62↓, 1,   TumAuto↑, 2,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↑, 3,   P53↑, 2,   PARP↑, 2,   cl‑PARP↑, 2,   cl‑PARP1↑, 1,  

Cell Cycle & Senescence(tgid=11) ⓘ

CDK2↓, 1,   CDK4↓, 2,   CDK6↑, 1,   cycD1/CCND1↓, 2,   cycE/CCNE↓, 1,   P21↑, 2,   TumCCA↑, 7,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

CSCs↓, 1,   Diff↑, 1,   FGF↓, 1,   Gli↓, 1,   HH↓, 1,   JAG1↓, 1,   mTORC1↓, 1,   NOTCH↓, 1,   NOTCH1↓, 2,   TumCG↓, 4,   TumCG↑, 1,   TumCP↓, 11,   Wnt↓, 3,  

Migration(tgid=13) ⓘ

AP-1↓, 2,   Ca+2↑, 2,   COL1↓, 1,   E-cadherin↑, 2,   EMT↓, 4,   MALAT1↓, 1,   MMP1↓, 1,   MMP2↓, 10,   MMP2↑, 1,   MMP9↓, 13,   MMP9↑, 1,   MMPs↓, 1,   Slug↓, 1,   Snail↓, 1,   TGF-β1↓, 1,   TIMP1↑, 2,   TIMP2↓, 1,   TIMP2↑, 1,   TumCI↓, 4,   TumCMig↓, 6,   TumMeta↓, 4,   TumMeta↑, 1,   uPA↓, 1,   Vim↓, 2,   β-catenin/ZEB1↓, 4,  

Angiogenesis & Vasculature(tgid=14) ⓘ

angioG↓, 6,   Hif1a↓, 2,   VEGF↓, 4,   VEGFR2/KDR/Flk1↓, 1,  

Barriers & Transport(tgid=15) ⓘ

EPR↑, 2,   MMP↓, 4,   MPT↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD47↓, 1,   CD59↑, 1,   CD8+↑, 2,   COX2/PTGS2↓, 5,   CXCR4↓, 2,   IFN-γ↓, 1,   IFN-γ↑, 1,   IL10↑, 2,   IL1β↓, 1,   IL1β↑, 1,   IL2↓, 1,   IL2↑, 1,   IL4↑, 1,   IL6↓, 2,   Inflam↓, 2,   NF-kB?, 1,   NF-kB↓, 4,   NF-kB↑, 1,   NK cell↑, 6,   PGE2↓, 2,   TNF-α↓, 3,   TNF-α↑, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

AR↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↑, 3,   BioAv↝, 1,   ChemoSen↑, 10,   CompStab↓, 1,   CYP1A1↓, 1,   DDS↑, 4,   Dose?, 1,   Dose↑, 1,   Dose↝, 7,   eff↓, 1,   eff↑, 10,   eff↝, 1,   Half-Life↑, 2,   MDR1↓, 1,   P-gp/ABCB1↓, 1,   RadioS↑, 3,   selectivity↑, 7,   Synergy↑, 6,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 2,   AR↓, 1,   AST↓, 1,   CEA↓, 1,   CIT↓, 1,   EGFR↑, 1,   EZH2↓, 1,   HER2/EBBR2↓, 1,   IL6↓, 2,  

Functional Outcomes(tgid=23) ⓘ

AntiArt↑, 1,   AntiCan↑, 8,   antiD↑, 1,   AntiTum↑, 8,   cachexia↓, 1,   chemoP↑, 7,   chemoPv↑, 2,   hepatoP↑, 2,   NP/CIPN↓, 1,   OS↑, 1,   PFS↑, 1,   QoL↑, 1,   radioP↑, 5,   RenoP↑, 1,   Risk↓, 4,   toxicity↓, 3,   toxicity↝, 1,   TumVol↓, 1,  

Infection & Microbiome(tgid=24) ⓘ

Sepsis↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

Api↑, 1,   Ingr↝, 1,  
Total Targets: 202

Pathway results for Effect on Normal Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

antiOx↓, 3,   antiOx↑, 33,   Catalase↓, 1,   Catalase↑, 10,   DPPH↓, 1,   GPx↓, 1,   GPx↑, 7,   GSH↓, 1,   GSH↑, 8,   GSTs↑, 3,   H2O2↓, 1,   HDL↑, 2,   HO-1↑, 4,   hyperG↓, 1,   Keap1↑, 1,   lipid-P↓, 8,   MDA↓, 9,   MPO↓, 1,   NADH↓, 1,   NRF2↑, 4,   RNS↓, 1,   ROS↓, 22,   selenoP↑, 2,   SOD↓, 1,   SOD↑, 15,   TAC↑, 2,   TBARS↓, 1,   uricA↓, 1,   VitC↑, 2,  

Metal & Cofactor Biology(tgid=2) ⓘ

IronCh↑, 1,  

Mitochondria & Bioenergetics(tgid=3) ⓘ

compII↑, 1,   compIII↑, 1,  

Core Metabolism/Glycolysis(tgid=4) ⓘ

5LO↓, 4,   5LO↝, 1,   ALAT↓, 6,   AMPK↑, 1,   ATP↑, 2,   glucose↓, 2,   GSK‐3β↓, 1,   LDL↓, 4,  

Cell Death(tgid=5) ⓘ

Apoptosis↓, 2,   BAX↓, 1,   Bcl-2↑, 1,   Casp12↓, 1,   Casp3↓, 1,   Cyt‑c↓, 1,   GranB/GZMB↓, 1,   iNOS↓, 2,   necrosis↓, 1,   p38↓, 1,  

Kinase & Signal Transduction(tgid=6) ⓘ

Akt↓, 1,   Akt↑, 2,   p‑Akt↑, 1,   p‑JNK↓, 1,   mTOR↓, 3,   mTOR↑, 1,   PI3K↓, 2,   PI3K↑, 2,   STAT3↑, 1,   p‑STAT3↑, 1,  

Transcription & Epigenetics(tgid=7) ⓘ

AntiThr↑, 2,   ATF4↓, 1,   HOTAIR↑, 1,   other↓, 4,   other↑, 3,   other↝, 10,  

Protein Folding & ER Stress(tgid=8) ⓘ

CHOP/DDIT3↓, 1,   p‑eIF2α↓, 1,   ER Stress↓, 1,   GRP78/BiP↓, 1,   XBP-1↓, 1,  

Autophagy & Lysosomes(tgid=9) ⓘ

LC3‑Ⅱ/LC3‑Ⅰ↑, 1,  

DNA Damage & Repair(tgid=10) ⓘ

DNAdam↓, 2,  

Migration(tgid=13) ⓘ

AntiAg↑, 6,   MMP13↓, 1,   TGF-β↓, 1,   TGF-β↑, 1,   Tyro3↓, 1,  

Angiogenesis & Vasculature(tgid=14) ⓘ

Hif1a↓, 1,   NO↓, 1,   VEGF↓, 1,  

Barriers & Transport(tgid=15) ⓘ

BBB↑, 3,   GastroP↑, 5,   IBI↑, 1,   MMP↑, 2,   TRPM7↓, 1,   ZO-1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

CD4+↑, 4,   CD8+↑, 1,   COX1↓, 3,   COX2/PTGS2↓, 10,   Dectin1↑, 1,   IFN-γ↓, 2,   IgA↑, 1,   IL1↓, 1,   IL10↓, 1,   IL10↑, 2,   IL12↓, 1,   IL17↓, 1,   IL1β↓, 5,   IL4↓, 1,   IL6↓, 8,   IL6↑, 2,   IL8↓, 1,   Imm↑, 83,   Inflam↓, 48,   LPS↓, 1,   MCP1/CCL2↓, 1,   MyD88↓, 1,   Neut↑, 1,   NF-kB↓, 9,   NK cell↑, 7,   NLRP3↓, 3,   PGE2↓, 1,   Th1 response↑, 1,   TLR4↓, 1,   TNF-α↓, 10,   TNF-α↑, 2,  

Synaptic & Neurotransmission(tgid=18) ⓘ

AChE↓, 6,   ADAM10↑, 1,   BChE↓, 4,   BDNF↑, 1,   proBDNF↑, 1,   GABA↑, 1,   NGF↑, 1,  

Protein Aggregation(tgid=19) ⓘ

APOE4↓, 1,   APP↓, 1,   cl‑APP↑, 1,   Aβ↓, 7,   BACE/β-secretase↓, 4,   PSEN1/PS1↑, 1,   p‑tau↓, 1,  

Hormonal & Nuclear Receptors(tgid=20) ⓘ

PPARγ↓, 1,   PPARγ↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

BioAv↓, 1,   BioAv↑, 14,   BioAv⇅, 1,   BioAv↝, 6,   Dose?, 1,   Dose↓, 1,   Dose↑, 2,   Dose↝, 17,   eff↓, 1,   eff↑, 12,   eff↝, 1,   GSTA1↑, 1,   Half-Life↓, 1,   Half-Life↝, 2,   Synergy↑, 4,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 6,   AST↓, 7,   BP↓, 4,   creat↓, 2,   CRP↓, 2,   IL6↓, 8,   IL6↑, 2,   LDH↓, 1,   LDH↑, 1,   NOS2↓, 1,   Urea↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Analgesic↑, 1,   AntiAge↑, 2,   antiAll↑, 2,   AntiArt↑, 4,   AntiCan↑, 14,   antiD↑, 1,   AntiDiabetic↓, 2,   AntiDiabetic↑, 22,   antiPs↑, 2,   AntiTum↑, 6,   ANXi↓, 1,   cardioP↑, 17,   chemoPv↑, 3,   cognitive↑, 11,   diuretic↑, 3,   hepatoP↑, 21,   Learn↑, 1,   memory↑, 8,   Mood↑, 1,   motorD↑, 2,   neuroP?, 1,   neuroP↑, 22,   Obesity↓, 10,   Pain↓, 4,   QoL↑, 2,   radioP↑, 1,   RenoP↑, 5,   Risk↓, 3,   Sleep↑, 2,   Stroke↓, 2,   toxicity?, 1,   toxicity↓, 13,   toxicity↝, 2,   toxicity∅, 1,   Weight↓, 1,   Weight↝, 1,   Wound Healing↑, 12,  

Infection & Microbiome(tgid=24) ⓘ

AntiBio↓, 1,   AntiBio↑, 12,   AntiFungal↑, 3,   AntiViral↑, 6,   Bacteria↓, 15,   Bacteria↑, 1,   Dectin1↑, 1,   Diar↓, 1,   GutMicro↑, 11,   Inf↓, 1,   Sepsis↓, 1,  

Ingredients & Constituents(tgid=25) ⓘ

CA↑, 1,   Catechins↑, 1,   FA↑, 1,   Flav↑, 1,   GA↑, 1,   Ingr↝, 7,   Phen↑, 1,   QC↑, 1,  
Total Targets: 216

Scientific Paper Hit Count for: Imm, immunostimulatory
9 Echinacea
5 Dandelion Root
4 chitosan
3 Centella asiatica / Gotu kola → asiaticoside
3 Chyawanprash
3 Cichoric acid / Chicoric acid
3 diet Fermented Foods
3 Lactoferrin/Talactoferrin
2 Phyllanthus emblica/Emblica officinalis/Amla / Indian Gooseberry
2 Aloe anthraquinones
2 beta-glucans
2 Caffeic Acid Phenethyl Ester (CAPE)
2 Chlorella (Chlorella vulgaris)
2 Date Fruit Extract
2 Phycocyanin
2 Selenite (Sodium)
1 Astragalus
1 Anethole/trans-Anethole
1 Astaxanthin
1 Boswellia (frankincense)
1 Bruteridin(bergamot juice)
1 α-Bisabolol / Chamomile oil
1 Caffeic acid
1 Carvacrol
1 Cat’s Claw
1 Cynanbungeigenin C (CBC) and D (CBD)
1 Chlorogenic acid
1 Chlorophyllin
1 Chocolate
1 Carica papaya leaf extract
1 Cucurbitacin
1 D-limonene
1 EGCG (Epigallocatechin Gallate)
1 Emodin
1 Germanium Organic/Ge-132 / propagermanium (organogermanium)
1 Ginger/6-Shogaol/Gingerol
1 Hydrogen Gas
1 Indole-3-carbinol
1 Matrine
1 Mung Bean Sprouts
1 Isovitexin
1 Vitexin
1 Magnetic Fields
1 Moringa oleifera
1 Mucuna pruriens/Velvet Bean
1 Mushroom Lion’s Mane, Hericium erinaceus
1 Mushroom Maitake
1 Nasturtium, Indian Cress
1 Isothiocyanates
1 Neem
1 Nimbolide
1 Peppermint
1 Piperine
1 Selenium NanoParticles
1 Thyme
1 Thymol-Thymus vulgaris
1 Zerumbone
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:1332  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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