chemoPv Cancer Research Results
chemoPv, ChemoPreventive: Click to Expand ⟱
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| Type: |
Chemopreventive: An agent that lowers the probability of cancer development or delays progression from premalignant states.
Mechanisms
-Reduce DNA damage / mutagenesis
-Enhance detoxification or repair
-Modulate hormones or inflammation
-Promote differentiation or apoptosis of abnormal cells
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Scientific Papers found: Click to Expand⟱
*GutMicro∅, *chemoPv↑,
*p‑PPARγ↓, *cardioP↑, *AMPK↑, *BioAv↝, *Half-Life↝, *Half-Life↝, *Dose↑, *chemoPv↑, IL6↓, STAT3↓, ROS↓, OXPHOS↓, PCNA↓, LDH↓, AMPK↑, TumCCA↑, NOTCH3↓, Akt↓, Bcl-2↓, Casp3↑, Apoptosis↑, Synergy↑, NF-kB↓, CSCs↓, HSP90↓, PI3K↓, FOXO3↑, β-catenin/ZEB1↓, N-cadherin↓, EMT↓, FASN↓, ACLY↓, ROS↑, NRF2↑, HO-1↑, NQO1↑, JNK↑, mTOR↓, neuroP↑, *TNF-α↓, *IL1β↓, *IL6↓, *IL8↓, *IL18↓, RadioS↑, ChemoSen↑,
Apoptosis↑, EMT↓, AntiCan↑, *cardioP↑, *neuroP↑, TumCG↓, *antiOx↑, *Bacteria↓, *Imm↑, *hepatoP↑, *AntiDiabetic↑, ROS↓, *chemoPv↑,
*hs-CRP↓, *TNF-α↓, *SOD↑, *Catalase↑, *GPx↑, *cognitive↑, *memory↑, *Risk↓, *SAM-e↑, *NAD↝, *ATP↝, *Ca+2↝, HDAC↓, TumVol↓, IGF-1↓, PSA↓, Cyc↓, TumCMig↓, *serineP↓, HIF-1↓, *ChemoSideEff↓, *VitD↑, *Mag↑, *Synergy↑, Risk↓, *Inflam↓, *neuroP↑, *Calcium↑, *BMD↑, *chemoP↑, AntiCan↑, *Dose↑, *Dose↝, *BMPs↑, *testos↑, angioG↓, Apoptosis↑, *selectivity↑, *chemoPv↑,
*antiOx↑, *chemoPv↑, ROS↑, MMP2↓, MMP9↓, BioAv↓, eff↑, *Inflam↓, AMPK↑, lipid-P↑, Synergy↑, ChemoSen↑, *memory↑, *ROS↓,
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Review, |
Nor, |
NA |
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Review, |
AD, |
NA |
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- |
Review, |
Asthma, |
NA |
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*Inflam↓, *antiOx↑, *neuroP↑, *BioAv↑, *toxicity↓, *Pain↓, *TRPV3↑, *NRF2↑, *Ca+2↑, *ATP↑, *5LO↓, *COX2/PTGS2↓, PGE2↓, *hepatoP↑, *AntiAg↑, *Diar↓, *cardioP↑, *other↝, *chemoPv↑, *cognitive↑, *AChE↓, *GastroP↑, *Synergy↑, *BChE↓, *CRP↓, *antiAll↑,
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Review, |
Var, |
NA |
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Review, |
AD, |
NA |
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Review, |
Diabetic, |
NA |
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antiOx↑, *Bacteria↓, AntiCan↑, *Inflam↓, *cardioP↑, *AntiDiabetic↑, *GutMicro↑, *eff↑, *eff↑, *ROS↓, *IronCh↑, *neuroP↑, *AChE↓, *BChE↓, *chemoPv↑, *BioAv⇅,
*eff↑, *chemoPv↑, *other↝,
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Review, |
Nor, |
NA |
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Review, |
Stroke, |
NA |
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Review, |
IBD, |
NA |
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*lipid-P↓, *ROS↓, *Inflam↓, *BP↓, *cardioP↑, *chemoPv↑, *BioAv⇅, *antiOx↑, *Risk↓, *5LO↓, *AntiAg↑, *Imm↑, *NF-kB↓, *other↓, CYP1A1↓, COX2/PTGS2↓, *Obesity↓, *cognitive↑,
selectivity↑, TumCP↓, p‑Akt↓, NF-kB↓, TumCG↓, *BioAv↑, *chemoPv↑,
*chemoPv↑, *ROS↓, *Inflam↓,
TumCP↓, Apoptosis↑, Casp↑, PCNA↓, p38↑, NF-kB↑, DNAdam↑, XIAP↓, Cyt‑c↑, Casp3↑, Akt↓, SCF↓, hTERT/TERT↓, COX2/PTGS2↓, *Inflam↓, *antiOx↑, *chemoPv↑, AR-V7?, CYP19?,
*neuroP↑, *Inflam↓, *ROS↓, NF-kB↓, *PCNA↓, *COX2/PTGS2↓, ChemoSen↑, Hif1a↓, angioG↓, *chemoPv↑, PDGF↓, *memory↑, *RenoP↑, *PPARα↑, *lipidLev↓, *hepatoP↑, *cardioP⇅, *BioAv↓,
*chemoPv↑, *antiOx↑, Apoptosis↑, TumCP↓, Diff↑, TumCCA↑, TumCG↓, TOP2↓, hTERT/TERT↓, Inflam↓, IL1β↓, TNF-α↓, Casp8↑, BAX↑, Cyt‑c↑, ChemoSen↑, RadioS↑, Apoptosis↑, cycD1/CCND1↓, P21↑, p27/CDKN1B↑, Bcl-2↓, Bax:Bcl2↑, Casp9↑, EMT↓, E-cadherin↑, β-catenin/ZEB1↓, N-cadherin↓,
*Inflam↓, *antiOx↑, *hepatoP↑, AntiTum↑, AntiCan↑, *chemoPv↑, *AntiDiabetic↑, *Imm↑, Hif1a↓, P-gp/ABCB1↓, mTORC1↓, ERK↓, Akt↓, Casp3↑, Casp7↑, ATP↓, RadioS↑, ChemoSen↑,
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in-vitro, |
Pca, |
DU145 |
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in-vitro, |
Pca, |
PC3 |
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miR-143↑, PDK1 / PDPK1↓, FOXD3↑, TumCP↓, TumCMig↓, *Inflam↓, *antiOx↑, *chemoPv↑, RadioS↑, ChemoSen↑,
*chemoPv↑, *Dose↝, *Half-Life?, *BioAv↝, NA↑, CYP1A2↑, 2/16-OHE1↑, AR↝, BioAv↑,
COX2/PTGS2↓, *GSH↑, *GPx↑, *Catalase↑, Bcl-2↓, BAX↑, *chemoPv↑, *Inflam↓, *ROS↓, *RAS↓,
*eff↑, *BioAv↝, *CompStab↝, *BioAv↑, *antiOx↑, *AntiAg↑, *Inflam↓, *AntiBio↑, *MAOA↓, *neuroP↑, *ROS↓, *RNS↓, *Synergy↑, NF-kB↓, PGE2↓, COX2/PTGS2↓, TumCCA↑, Apoptosis↑, TumCMig↓, TumCI↓, tumCV↓, PI3K↓, Akt↓, MMPs↓, ChemoSen↑, ALDH↓, *Pain↓, *VGSC↓, *IL1β↓, *IL6↓, *TNF-α↓, *iNOS↓, *5LO↓, *chemoPv↑, *antiAll↑,
*chemoPv↑, *neuroP↑, *antiOx↑, *GSH↑, *HO-1↑, *NRF2↑, angioG↓, TumCG↓, uPA↓, MMP1↓, tumCV↓, PTEN↑, PI3K↓, p‑Akt↓, AMPK↑, mTOR↓, EGFR↓, NF-kB↓, COX2/PTGS2↓, PGE2↓, Wnt↓, β-catenin/ZEB1↓, TCF↓, cycD1/CCND1↓, MMP7↓, RadioS↑, PSA↓, Securin↓, TumCCA↑, XIAP↓, *ERK↑, *p‑CREB↑, *memory↑, *GSH↑, *Inflam↓, *5LO↓,
*neuroP↑, *cardioP↑, *chemoPv↑, *AntiDiabetic↑, *Inflam↓, *ROS↓, *BioAv↓, *BioAv↑, *eff↑, *Half-Life↓,
*BioAv↝, *Dose↝, *Inflam↓, *antiOx↑, *chemoPv↑, Wnt↓, β-catenin/ZEB1↓, ERK↓, PI3K↓, Akt↓, NF-kB↓, STAT3↓, TumCP↓, antiNeop↑, ChemoSen↑, chemoP↑,
*Dose↝, *other↓, *chemoPv↑,
*ROS?, *IronCh↑, *chemoPv↑,
*GSH↑, *GSTs↑, *chemoPv↑,
TumCG↓, Apoptosis↑, BAX↑, cl‑Casp3↑, cl‑PARP↑, Cyt‑c↑, TumAuto↑, LC3II↑, ATG3↑, ATG5↑, Beclin-1/ATG6↑, ER Stress↑, IRE1↑, XBP-1↑, CHOP/DDIT3↑, GRP78/BiP↑, *chemoPv↑,
CRP↓, AFP↓, CEA↓, CA19-9↓, Ki-67↓, Apoptosis↑, Casp3↑, cl‑Casp3↑, BAX↑, Bcl-2↓, *ROS↓, *Inflam↓, *Catalase↑, *SOD↑, *GSH↑, *MDA↓, *IL1β↓, *TNF-α↓, *IL6↓, *IL10↓, *COX2/PTGS2↓, *NF-kB↓, *NLRP3↓, *GutMicro↑, *chemoPv↑, *Dose↝, Ki-67↓,
*antiOx↑, *Inflam↓, *AntiCan↑, *chemoPv↑, *Ingr↝, *AntiDiabetic↑, *hepatoP↑, *Bacteria↓, *AntiFungal↑, Apoptosis↑, ROS↑, DNAdam↑, Casp3↑, TumCCA↑, ROS↓, chemoP↑,
*CYP2E1↓, *chemoPv↑,
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in-vitro, |
Pca, |
LNCaP |
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in-vitro, |
Pca, |
PC3 |
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Risk↓, miR-194↑, TumCI↓, MMP2↓, MMP9↓, BMP2↓, *chemoPv↑,
*AMPK↑, *P21↑, *Dose↓, *chemoPv↑,
*Inflam↓, *antiOx↑, *AntiAg↑, *chemoPv↑, ChemoSen↑, BioAv↑, Half-Life↝, COX2/PTGS2↓, cycD1/CCND1↓, CDK2↓, CDK4↓, CDK6↓, P21↑, MMP9↓, NF-kB↓, Telomerase↓, PSA↓, MAPK↑, P53↑,
*antiOx↑, *Inflam↓, *chemoPv↑, CSCs↓, Wnt↓, β-catenin/ZEB1↓, NOTCH↓, PI3K↓, Akt↓, mTOR↓, GSK‐3β↝, Snail↓, HH↓, p‑GSK‐3β↓, N-cadherin↓, EMT↓, CD133↓, CD44↓, ALDH1A1↓, OCT4↓, SOX4↓, Shh↓, Smo↓, Gli1↓, GLI2↓,
*chemoPv↑, Apoptosis↑, Casp↑, MMP↓, Cyt‑c↑, TumCCA↑, TumCG↓,
*ROS↓, *chemoPv↑, ROS↑, ROS⇅, MUC4↓, selectivity↑, AR↓, cycD1/CCND1↓, Bcl-2↓, Bcl-xL↓, survivin↓, Mcl-1↓, VEGF↓, cl‑PARP↑, ROS↑, HSP70/HSPA5↑, P53↑, miR-34a↑, Rac1↓, TumCCA↑, NOTCH↓, NF-kB↓, IκB↓, p‑p65↓, IAP1↓, IAP2/BIRC3↑, XIAP↓, TNF-α↓, COX2/PTGS2↓, Inflam↓, α-tubulin↓, Twist↓, EMT↓, mTOR↓, PI3K↓, Akt↓, BioAv↓, ChemoSen↑, CompStab↑, PTEN↑, chemoPv↑, RadioS↑, *Half-Life↝, *BioAv↝,
Showing Research Papers: 1 to 35 of 35
* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 35
Pathway results for Effect on Cancer / Diseased Cells:
NA, unassigned(tgid=0) ⓘ
NA↑, 1,
Redox & Oxidative Stress(tgid=1) ⓘ
antiOx↑, 1, HO-1↑, 1, lipid-P↑, 1, NQO1↑, 1, NRF2↑, 1, ROS↓, 3, ROS↑, 5, ROS⇅, 1,
Mitochondria & Bioenergetics(tgid=3) ⓘ
OXPHOS↓, 1,
Core Metabolism/Glycolysis(tgid=4) ⓘ
ACLY↓, 1, AMPK↑, 3, ATP↓, 1, FASN↓, 1, GSK‐3β↝, 1, p‑GSK‐3β↓, 1, PDK1 / PDPK1↓, 1,
Cell Death(tgid=5) ⓘ
Apoptosis↑, 11, BAX↑, 4, Bax:Bcl2↑, 1, Bcl-2↓, 5, Bcl-xL↓, 1, Casp↑, 2, Casp3↑, 5, cl‑Casp3↑, 2, Casp7↑, 1, Casp8↑, 1, Casp9↑, 1, Cyt‑c↑, 4, IAP1↓, 1, IAP2/BIRC3↑, 1, Mcl-1↓, 1, p38↑, 1, survivin↓, 1, XIAP↓, 3,
Kinase & Signal Transduction(tgid=6) ⓘ
Akt↓, 7, p‑Akt↓, 2, EGFR↓, 1, ERK↓, 2, FOXD3↑, 1, IκB↓, 1, JNK↑, 1, MAPK↑, 1, mTOR↓, 4, PI3K↓, 6, PTEN↑, 2, STAT3↓, 2,
Transcription & Epigenetics(tgid=7) ⓘ
FOXO3↑, 1, HDAC↓, 1, miR-143↑, 1, miR-194↑, 1, miR-34a↑, 1, OCT4↓, 1, SOX4↓, 1, tumCV↓, 2,
Protein Folding & ER Stress(tgid=8) ⓘ
CHOP/DDIT3↑, 1, ER Stress↑, 1, GRP78/BiP↑, 1, HSP70/HSPA5↑, 1, HSP90↓, 1, IRE1↑, 1, XBP-1↑, 1,
Autophagy & Lysosomes(tgid=9) ⓘ
ATG3↑, 1, ATG5↑, 1, Beclin-1/ATG6↑, 1, LC3II↑, 1, TumAuto↑, 1,
DNA Damage & Repair(tgid=10) ⓘ
DNAdam↑, 2, hTERT/TERT↓, 2, P53↑, 2, cl‑PARP↑, 2, PCNA↓, 2, Telomerase↓, 1, TOP2↓, 1,
Cell Cycle & Senescence(tgid=11) ⓘ
CDK2↓, 1, CDK4↓, 1, CDK6↓, 1, Cyc↓, 1, cycD1/CCND1↓, 4, Ki-67↓, 2, P21↑, 2, p27/CDKN1B↑, 1, Securin↓, 1, TumCCA↑, 7,
Proliferation, Differentiation & Cell State(tgid=12) ⓘ
ALDH↓, 1, ALDH1A1↓, 1, BMP2↓, 1, CD133↓, 1, CSCs↓, 2, Diff↑, 1, Gli1↓, 1, HH↓, 1, IGF-1↓, 1, Ki-67↓, 2, mTORC1↓, 1, NOTCH↓, 2, NOTCH3↓, 1, SCF↓, 1, Shh↓, 1, Smo↓, 1, TumCG↓, 6, TumCP↓, 5, Wnt↓, 3,
Migration(tgid=13) ⓘ
E-cadherin↑, 1, EMT↓, 5, GLI2↓, 1, MMP1↓, 1, MMP2↓, 2, MMP7↓, 1, MMP9↓, 3, MMPs↓, 1, MUC4↓, 1, N-cadherin↓, 3, PDGF↓, 1, Rac1↓, 1, Snail↓, 1, TumCI↓, 2, TumCMig↓, 3, Twist↓, 1, uPA↓, 1, α-tubulin↓, 1, β-catenin/ZEB1↓, 5,
Angiogenesis & Vasculature(tgid=14) ⓘ
angioG↓, 3, HIF-1↓, 1, Hif1a↓, 2, VEGF↓, 1,
Barriers & Transport(tgid=15) ⓘ
MMP↓, 1,
Immune & Inflammatory Signaling(tgid=16) ⓘ
CD44↓, 1, COX2/PTGS2↓, 7, IL1β↓, 1, IL6↓, 1, Inflam↓, 2, NF-kB↓, 8, NF-kB↑, 1, p‑p65↓, 1, PGE2↓, 3, PSA↓, 3, TCF↓, 1, TNF-α↓, 2,
Hormonal & Nuclear Receptors(tgid=20) ⓘ
2/16-OHE1↑, 1, AR↓, 1, AR↝, 1, AR-V7?, 1, CYP19?, 1,
Drug Metabolism & Resistance(tgid=21) ⓘ
BioAv↓, 2, BioAv↑, 2, ChemoSen↑, 10, CompStab↑, 1, CYP1A1↓, 1, CYP1A2↑, 1, eff↑, 1, Half-Life↝, 1, P-gp/ABCB1↓, 1, RadioS↑, 6, selectivity↑, 2, Synergy↑, 2,
Clinical Biomarkers(tgid=22) ⓘ
AFP↓, 1, AR↓, 1, AR↝, 1, CA19-9↓, 1, CEA↓, 1, CRP↓, 1, EGFR↓, 1, hTERT/TERT↓, 2, IL6↓, 1, LDH↓, 1, PSA↓, 3,
Functional Outcomes(tgid=23) ⓘ
AntiCan↑, 4, antiNeop↑, 1, AntiTum↑, 1, chemoP↑, 2, chemoPv↑, 1, neuroP↑, 1, Risk↓, 2, TumVol↓, 1,
Total Targets: 175
Pathway results for Effect on Normal Cells:
Redox & Oxidative Stress(tgid=1) ⓘ
antiOx↑, 14, Catalase↑, 3, GPx↑, 2, GSH↑, 5, GSTs↑, 1, HO-1↑, 1, lipid-P↓, 1, MDA↓, 1, NRF2↑, 2, RNS↓, 1, ROS?, 1, ROS↓, 10, SAM-e↑, 1, SOD↑, 2,
Metal & Cofactor Biology(tgid=2) ⓘ
IronCh↑, 2,
Core Metabolism/Glycolysis(tgid=4) ⓘ
5LO↓, 4, AMPK↑, 2, ATP↑, 1, ATP↝, 1, lipidLev↓, 1, NAD↝, 1,
Cell Death(tgid=5) ⓘ
iNOS↓, 1,
Kinase & Signal Transduction(tgid=6) ⓘ
p‑CREB↑, 1, ERK↑, 1, RAS↓, 1,
Transcription & Epigenetics(tgid=7) ⓘ
other↓, 2, other↝, 2,
DNA Damage & Repair(tgid=10) ⓘ
PCNA↓, 1,
Cell Cycle & Senescence(tgid=11) ⓘ
P21↑, 1,
Proliferation, Differentiation & Cell State(tgid=12) ⓘ
BMPs↑, 1,
Migration(tgid=13) ⓘ
AntiAg↑, 4, Ca+2↑, 1, Ca+2↝, 1, serineP↓, 1,
Barriers & Transport(tgid=15) ⓘ
GastroP↑, 1, TRPV3↑, 1, VGSC↓, 1,
Immune & Inflammatory Signaling(tgid=16) ⓘ
COX2/PTGS2↓, 3, IL10↓, 1, IL18↓, 1, IL1β↓, 3, IL6↓, 3, IL8↓, 1, Imm↑, 3, Inflam↓, 19, NF-kB↓, 2, NLRP3↓, 1, TNF-α↓, 4, VitD↑, 1,
Synaptic & Neurotransmission(tgid=18) ⓘ
AChE↓, 2, BChE↓, 2, MAOA↓, 1,
Hormonal & Nuclear Receptors(tgid=20) ⓘ
PPARα↑, 1, p‑PPARγ↓, 1, testos↑, 1,
Drug Metabolism & Resistance(tgid=21) ⓘ
BioAv↓, 2, BioAv↑, 4, BioAv⇅, 2, BioAv↝, 5, CompStab↝, 1, CYP2E1↓, 1, Dose↓, 1, Dose↑, 2, Dose↝, 5, eff↑, 5, Half-Life?, 1, Half-Life↓, 1, Half-Life↝, 3, selectivity↑, 1, Synergy↑, 3,
Clinical Biomarkers(tgid=22) ⓘ
BMD↑, 1, BP↓, 1, Calcium↑, 1, CRP↓, 1, hs-CRP↓, 1, IL6↓, 3, Mag↑, 1, VitD↑, 1,
Functional Outcomes(tgid=23) ⓘ
antiAll↑, 2, AntiCan↑, 1, AntiDiabetic↑, 5, cardioP↑, 6, cardioP⇅, 1, chemoP↑, 1, chemoPv↑, 35, ChemoSideEff↓, 1, cognitive↑, 3, hepatoP↑, 5, memory↑, 4, neuroP↑, 8, Obesity↓, 1, Pain↓, 2, RenoP↑, 1, Risk↓, 2, toxicity↓, 1,
Infection & Microbiome(tgid=24) ⓘ
AntiBio↑, 1, AntiFungal↑, 1, Bacteria↓, 3, Diar↓, 1, GutMicro↑, 2, GutMicro∅, 1,
Ingredients & Constituents(tgid=25) ⓘ
Ingr↝, 1,
Total Targets: 102
Scientific Paper Hit Count for: chemoPv, ChemoPreventive
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include :
-low or high Dose
-format for product, such as nano of lipid formations
-different cell line effects
-synergies with other products
-if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:% IllCat:% CanType:% Cells:1 prod#:% Target#:1417 State#:% Dir#:2
wNotes=0 sortOrder:rid,rpid
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