Urea Cancer Research Results

Urea, Urea: Click to Expand ⟱
Source:
Type: Biomarker

Urea is the principal nitrogenous waste product formed in the liver through the urea cycle from ammonia generated during amino-acid metabolism. It is transported in blood and excreted mainly by the kidneys. Urea is a metabolite and clinical biomarker, not a molecular signalling target. Its direction is context-dependent: increased serum urea may indicate renal impairment, dehydration, protein catabolism, or treatment toxicity, while reduced urea may reflect impaired hepatic synthesis, malnutrition, or altered nitrogen metabolism. Reference.



Scientific Papers found: Click to Expand⟱
8904- MOR,    A 13-week subchronic toxicity study of dietary administered morin in F344 rats
- in-vivo, Nor, NA
*Dose?, *ALAT↓, *ALP↓, *creat↑, *Urea↑, *toxicity↝,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Total Targets: 0

Pathway results for Effect on Normal Cells:


Core Metabolism/Glycolysis(tgid=4) ⓘ

ALAT↓, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

Dose?, 1,  

Clinical Biomarkers(tgid=22) ⓘ

ALAT↓, 1,   ALP↓, 1,   creat↑, 1,   Urea↑, 1,  

Functional Outcomes(tgid=23) ⓘ

toxicity↝, 1,  
Total Targets: 7

Scientific Paper Hit Count for: Urea, Urea
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells
Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:1535  State#:%  Dir#:2
wNotes=0 sortOrder:rid,rpid

 

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