DCells Cancer Research Results

DCells, dendritic Cells: Click to Expand ⟱
Source:
Type:
Dendritic cells (DCs) are central regulators of the adaptive immune response, and as such are necessary for T cell-mediated cancer immunity.
DC subsets are often classified by developmental origin as conventional DC [including type 1 conventional DC (cDC1) and type 2 conventional DC (cDC2)], monocyte-derived DC (MoDC), plasmacytoid DC (pDC) as well as the emerging appreciation of a population, termed DC3.

Dendritic cells play a vital role in the immune response to cancer, and their presence and functional status in the tumor microenvironment can significantly impact prognosis. Generally, a higher density of activated dendritic cells is associated with better clinical outcomes across various cancer types.
Scientific Papers found: Click to Expand⟱
5988- Chit,    Chitosan immunomodulation: insights into mechanisms of action on immune cells and signaling pathways
- Review, Var, NA
DDS↑, *Cartilage↑, *Wound Healing↑, Imm↑, cGAS–STING↑, STAT1↑, NLRP3↑, *DCells↑, *IL10↓, *TGF-β1↓, *TNF-α↓, IL1β↓, ROS↑,

Showing Research Papers: 1 to 1 of 1

* indicates research on normal cells as opposed to diseased cells
Total Research Paper Matches: 1

Pathway results for Effect on Cancer / Diseased Cells:


Redox & Oxidative Stress(tgid=1) ⓘ

ROS↑, 1,  

Proliferation, Differentiation & Cell State(tgid=12) ⓘ

STAT1↑, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

cGAS–STING↑, 1,   IL1β↓, 1,   Imm↑, 1,   NLRP3↑, 1,  

Drug Metabolism & Resistance(tgid=21) ⓘ

DDS↑, 1,  
Total Targets: 7

Pathway results for Effect on Normal Cells:


Migration(tgid=13) ⓘ

Cartilage↑, 1,   TGF-β1↓, 1,  

Immune & Inflammatory Signaling(tgid=16) ⓘ

DCells↑, 1,   IL10↓, 1,   TNF-α↓, 1,  

Functional Outcomes(tgid=23) ⓘ

Wound Healing↑, 1,  
Total Targets: 6

Scientific Paper Hit Count for: DCells, dendritic Cells
Query results interpretion may depend on "conditions" listed in the research papers.
Such Conditions may include : 
  -low or high Dose
  -format for product, such as nano of lipid formations
  -different cell line effects
  -synergies with other products 
  -if effect was for normal or cancerous cells

Filter Conditions: Pro/AntiFlg:%  IllCat:%  CanType:%  Cells:1  prod#:%  Target#:572  State#:%  Dir#:2
  wNotes=0  sortOrder:rid,rpid

 

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